-
1
-
-
0029099408
-
Assay and expression of mitogen-activated protein-kinase, Map kinase, and raf
-
Alessi, D. R., P. Cohen, A. Ashworth, S. Cowley, S. J. Leever, and C. J. Marshall. 1995. Assay and expression of mitogen-activated protein-kinase, Map kinase, and Raf. Methods Enzymol. 255:279-290.
-
(1995)
Methods Enzymol.
, vol.255
, pp. 279-290
-
-
Alessi, D.R.1
Cohen, P.2
Ashworth, A.3
Cowley, S.4
Leever, S.J.5
Marshall, C.J.6
-
2
-
-
0032518467
-
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
-
Alessi, D. R., M. T. Kozlowski, Q. P. Weng, N. Morrice, and J. Avruch. 1998. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr. Biol. 8:69-81.
-
(1998)
Curr. Biol.
, vol.8
, pp. 69-81
-
-
Alessi, D.R.1
Kozlowski, M.T.2
Weng, Q.P.3
Morrice, N.4
Avruch, J.5
-
3
-
-
0029893702
-
The origin of programmed cell death
-
Ameisen, J. C. 1996. The origin of programmed cell death. Science 272:1278-1279.
-
(1996)
Science
, vol.272
, pp. 1278-1279
-
-
Ameisen, J.C.1
-
4
-
-
0030829750
-
Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids
-
An, S., T. Bleu, W. Huang, O. G. Hallmark, S. R. Coughlin, and E. J. Goetzl. 1997. Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids. FEBS Lett. 417:279-282.
-
(1997)
FEBS Lett.
, vol.417
, pp. 279-282
-
-
An, S.1
Bleu, T.2
Huang, W.3
Hallmark, O.G.4
Coughlin, S.R.5
Goetzl, E.J.6
-
5
-
-
0025739993
-
Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids
-
Buede, R., S. C. Rinker, W. J. Pinto, R. L. Lester, and R. C. Dickson. 1991. Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids. J. Bacteriol. 173:4325-4332.
-
(1991)
J. Bacteriol.
, vol.173
, pp. 4325-4332
-
-
Buede, R.1
Rinker, S.C.2
Pinto, W.J.3
Lester, R.L.4
Dickson, R.C.5
-
6
-
-
0033602281
-
Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast
-
Casamayor, A., P. D. Torrance, T. Kobayashi, J. Thorner, and D. R. Alessi. 1999. Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast. Curr. Biol. 9:186-197.
-
(1999)
Curr. Biol.
, vol.9
, pp. 186-197
-
-
Casamayor, A.1
Torrance, P.D.2
Kobayashi, T.3
Thorner, J.4
Alessi, D.R.5
-
7
-
-
0027476071
-
A pair of putative protein kinase genes (YPK1 and YPK2) is required for cell growth in Saccharomyces cerevisiae
-
Chen, P., K. S. Lee, and D. E. Levin. 1993. A pair of putative protein kinase genes (YPK1 and YPK2) is required for cell growth in Saccharomyces cerevisiae. Mol. Gen. Genet. 236:443-447.
-
(1993)
Mol. Gen. Genet.
, vol.236
, pp. 443-447
-
-
Chen, P.1
Lee, K.S.2
Levin, D.E.3
-
8
-
-
0032544011
-
Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase
-
Cheng, X., Y. Ma, M. Moore, B. A. Hemmings, and S. S. Taylor. 1998. Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase. Proc. Natl. Acad. Sci. USA 95:9849-9854.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9849-9854
-
-
Cheng, X.1
Ma, Y.2
Moore, M.3
Hemmings, B.A.4
Taylor, S.S.5
-
9
-
-
0029996293
-
FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats
-
Chiba, K., Y. Hoshino, C. Suzuki, Y. Masubuchi, Y. Yanagawa, M. Ohtsuki, S. Sasaki, and T. Fujita. 1996. FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats. Transplant. Proc. 28:1056-1059.
-
(1996)
Transplant. Proc.
, vol.28
, pp. 1056-1059
-
-
Chiba, K.1
Hoshino, Y.2
Suzuki, C.3
Masubuchi, Y.4
Yanagawa, Y.5
Ohtsuki, M.6
Sasaki, S.7
Fujita, T.8
-
10
-
-
0032525049
-
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing
-
Chiba, K., Y. Yanagawa, Y. Masubuchi, H. Kataoka, T. Kawaguchi, M. Ohtsuki, and Y. Hoshino. 1998. FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing. J. Immunol. 160:5037-5044.
-
(1998)
J. Immunol.
, vol.160
, pp. 5037-5044
-
-
Chiba, K.1
Yanagawa, Y.2
Masubuchi, Y.3
Kataoka, H.4
Kawaguchi, T.5
Ohtsuki, M.6
Hoshino, Y.7
-
11
-
-
0028095477
-
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase
-
Cifone, M. G., R. De-Maria, P. Roncaioli, M. R. Rippo, M. Azuma, L. L. Lanier, A. Santoni, and R. Testi. 1994. Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase. J. Exp. Med. 180:1547-1552.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1547-1552
-
-
Cifone, M.G.1
De-Maria, R.2
Roncaioli, P.3
Rippo, M.R.4
Azuma, M.5
Lanier, L.L.6
Santoni, A.7
Testi, R.8
-
12
-
-
0026601458
-
Site-directed mutagenesis of virtually any plasmid by eliminating a unique site
-
Deng, W. P., and J. A. Nickoloff. 1992. Site-directed mutagenesis of virtually any plasmid by eliminating a unique site. Anal. Biochem. 200:81-88.
-
(1992)
Anal. Biochem.
, vol.200
, pp. 81-88
-
-
Deng, W.P.1
Nickoloff, J.A.2
-
13
-
-
0033583076
-
Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta
-
Dong, L. Q., R. B. Zhang, P. Langlais, H. He, M. Clark, L. Zhu, and F. Liu. 1999. Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta. J. Biol. Chem. 274:8117-8122.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8117-8122
-
-
Dong, L.Q.1
Zhang, R.B.2
Langlais, P.3
He, H.4
Clark, M.5
Zhu, L.6
Liu, F.7
-
14
-
-
0030669546
-
Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis
-
Dove, S. K., F. T. Cooke, M. R. Douglas, L. G. Sayers, P. J. Parker, and R. H. Michell. 1997. Osmotic stress activates phosphatidylinositol-3,5-bisphosphate synthesis. Nature 390:187-192.
-
(1997)
Nature
, vol.390
, pp. 187-192
-
-
Dove, S.K.1
Cooke, F.T.2
Douglas, M.R.3
Sayers, L.G.4
Parker, P.J.5
Michell, R.H.6
-
15
-
-
0031028654
-
Fungicidal action of aureobasidin A, a cyclic depsipeptide antifungal antibiotic, against Saccharomyces cerevisiae
-
Endo, M., K. Takesako, I. Kato, and H. Yamaguchi. 1997. Fungicidal action of aureobasidin A, a cyclic depsipeptide antifungal antibiotic, against Saccharomyces cerevisiae. Antimicrob. Agents Chemother. 41:672-676.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 672-676
-
-
Endo, M.1
Takesako, K.2
Kato, I.3
Yamaguchi, H.4
-
16
-
-
0031915430
-
Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid
-
Erickson, J. R., J. J. Wu, J. G. Goddard, G. Tigyi, K. Kawanishi, L. D. Tomei, and M. C. Kiefer. 1998. Edg-2/Vzg-1 couples to the yeast pheromone response pathway selectively in response to lysophosphatidic acid. J. Biol. Chem. 273:1506-1510.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1506-1510
-
-
Erickson, J.R.1
Wu, J.J.2
Goddard, J.G.3
Tigyi, G.4
Kawanishi, K.5
Tomei, L.D.6
Kiefer, M.C.7
-
17
-
-
0028372227
-
Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite
-
Fujita, T., K. Inoue, S. Yamamoto, T. Ikumoto, S. Sasaki, R. Toyama, K. Chiba, Y. Hoshino, and T. Okumoto. 1994. Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J. Antibiot. (Tokyo) 47:208-215.
-
(1994)
J. Antibiot. (Tokyo)
, vol.47
, pp. 208-215
-
-
Fujita, T.1
Inoue, K.2
Yamamoto, S.3
Ikumoto, T.4
Sasaki, S.5
Toyama, R.6
Chiba, K.7
Hoshino, Y.8
Okumoto, T.9
-
18
-
-
0031866963
-
Ceramide and its interconvertible metabolite, sphingosine, the function as indispensable lipid factors involved in the survival and dendritic differentiation of cerebellar Purkinje cells
-
Furuya, S., J. Mitoma, A. Makino, and Y. Hirabayashi. 1998. Ceramide and its interconvertible metabolite, sphingosine, the function as indispensable lipid factors involved in the survival and dendritic differentiation of cerebellar Purkinje cells. J. Neurochem. 71:366-377.
-
(1998)
J. Neurochem.
, vol.71
, pp. 366-377
-
-
Furuya, S.1
Mitoma, J.2
Makino, A.3
Hirabayashi, Y.4
-
19
-
-
0021023293
-
The isolation and characterization of a mutant strain of Saccharomyces cerevisiae that requires a long chain base for growth and for synthesis of phosphosphingolipids
-
Gerald, B., and R. L. Lester. 1983. The isolation and characterization of a mutant strain of Saccharomyces cerevisiae that requires a long chain base for growth and for synthesis of phosphosphingolipids. J. Biol. Chem. 258:10200-10203.
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 10200-10203
-
-
Gerald, B.1
Lester, R.L.2
-
20
-
-
0028670374
-
Fas antigen and sphingomyelin-ceramide turnover-mediated signaling: Role in the life and death of T lymphocytes
-
Gill, B. M., H. Nishikata, G. Chan, T. L. Delovitch, and A. Ochi. 1994. Fas antigen and sphingomyelin-ceramide turnover-mediated signaling: role in the life and death of T lymphocytes. Immunol. Rev. 142:113-125.
-
(1994)
Immunol. Rev.
, vol.142
, pp. 113-125
-
-
Gill, B.M.1
Nishikata, H.2
Chan, G.3
Delovitch, T.L.4
Ochi, A.5
-
21
-
-
0028964917
-
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway
-
Gulbins, E., R. Bissonnette, A. Mahboubi, S. Martin, W. Nishioka, T. Brunner, G. Baier, G. Baier-Bitterlich, C. Byrd, F. Lang, R. Kolesnick, A. Altman, and D. Green. 1995. FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway. Immunity 2:341-351.
-
(1995)
Immunity
, vol.2
, pp. 341-351
-
-
Gulbins, E.1
Bissonnette, R.2
Mahboubi, A.3
Martin, S.4
Nishioka, W.5
Brunner, T.6
Baier, G.7
Baier-Bitterlich, G.8
Byrd, C.9
Lang, F.10
Kolesnick, R.11
Altman, A.12
Green, D.13
-
22
-
-
0025077629
-
Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions
-
Hakomori, S. 1990. Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions. J. Biol. Chem. 265:18713-18716.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 18713-18716
-
-
Hakomori, S.1
-
23
-
-
0027313133
-
Structure and function of sphingoglycolipids in transmembrane signaling and cell-cell interactions
-
Hakomori, S. 1993. Structure and function of sphingoglycolipids in transmembrane signaling and cell-cell interactions. Biochem. Soc. Trans. 21:583-595.
-
(1993)
Biochem. Soc. Trans.
, vol.21
, pp. 583-595
-
-
Hakomori, S.1
-
24
-
-
0028287960
-
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
-
Haimovitz-Friedman, A., C. C. Kan, D. Ehleiter, R. S. Persaud, M. McLoughlin, Z. Fuks, and R. N. Kolesnick. 1994. Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis. J. Exp. Med. 180:525-535.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 525-535
-
-
Haimovitz-Friedman, A.1
Kan, C.C.2
Ehleiter, D.3
Persaud, R.S.4
McLoughlin, M.5
Fuks, Z.6
Kolesnick, R.N.7
-
25
-
-
0030448021
-
Function of ceramide in coordinating cellular responsed to stress
-
Hannun, Y. A. 1996. Function of ceramide in coordinating cellular responsed to stress. Science 274:1855-1859.
-
(1996)
Science
, vol.274
, pp. 1855-1859
-
-
Hannun, Y.A.1
-
26
-
-
0024541436
-
Functions of sphingolipids and sphingolipid breakdown products in cellular regulation
-
Hannun, Y. A., and R. M. Bell. 1989. Functions of sphingolipids and sphingolipid breakdown products in cellular regulation. Science 243:500-507.
-
(1989)
Science
, vol.243
, pp. 500-507
-
-
Hannun, Y.A.1
Bell, R.M.2
-
27
-
-
0028855405
-
Ceramide: An intracellular signal for apoptosis
-
Hannun, Y. A., and L. M. Obeid. 1995. Ceramide: an intracellular signal for apoptosis. Trends Biochem. Sci. 20:73-77.
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 73-77
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
28
-
-
0018905705
-
The extraction of inositol-containing phospholipids and phosphatidylcholine from Saccharomyces cerevisiae and Neurospora crassa
-
Hanson, B. A., and R. L. Lester. 1981. The extraction of inositol-containing phospholipids and phosphatidylcholine from Saccharomyces cerevisiae and Neurospora crassa. J. Lipid Res. 21:309-315.
-
(1981)
J. Lipid Res.
, vol.21
, pp. 309-315
-
-
Hanson, B.A.1
Lester, R.L.2
-
29
-
-
0027407768
-
Analysis of inositol metabolites produced by Saccharomyces cerevisiae in response to glucose stimulation
-
Hawkins, P. T., L. R. Stephens, and J. R. Piggott. 1993. Analysis of inositol metabolites produced by Saccharomyces cerevisiae in response to glucose stimulation. Biol. Chem. 268:3374-3383.
-
(1993)
Biol. Chem.
, vol.268
, pp. 3374-3383
-
-
Hawkins, P.T.1
Stephens, L.R.2
Piggott, J.R.3
-
30
-
-
0032523042
-
Apoptotic signal of Fas is not mediated by ceramide
-
Heu, S. C., C. C. Wu, T. Y. Luh, C. K. Chou, S. H. Han, and M. Z. Lai. 1998. Apoptotic signal of Fas is not mediated by ceramide. Blood 91:2658-2663.
-
(1998)
Blood
, vol.91
, pp. 2658-2663
-
-
Heu, S.C.1
Wu, C.C.2
Luh, T.Y.3
Chou, C.K.4
Han, S.H.5
Lai, M.Z.6
-
31
-
-
0033566338
-
Sphingosine-1-phosphate: Extracellular mediator or intracellular second messenger?
-
Hla, T., M. J. Lee, N. Ancellin, C. H. Liu, S. Thangada, B. D. Thompson, and M. Kluk. 1999. Sphingosine-1-phosphate: extracellular mediator or intracellular second messenger? Biochem. Pharmacol. 58:201-207.
-
(1999)
Biochem. Pharmacol.
, vol.58
, pp. 201-207
-
-
Hla, T.1
Lee, M.J.2
Ancellin, N.3
Liu, C.H.4
Thangada, S.5
Thompson, B.D.6
Kluk, M.7
-
32
-
-
0025914473
-
Structure of aureobasidin A
-
Ikai, K., K. Takesako, K. Shiomi, M. Moriguchi, Y. Umeda, J. Yamamoto, I. Kato, and H. Naganawa. 1991. Structure of aureobasidin A. J. Antibiot. (Tokyo) 44:925-933.
-
(1991)
J. Antibiot. (Tokyo)
, vol.44
, pp. 925-933
-
-
Ikai, K.1
Takesako, K.2
Shiomi, K.3
Moriguchi, M.4
Umeda, Y.5
Yamamoto, J.6
Kato, I.7
Naganawa, H.8
-
33
-
-
0020529962
-
Transformation of intact yeast cells treated with alkali cations
-
Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:163-168.
-
(1983)
J. Bacteriol.
, vol.153
, pp. 163-168
-
-
Ito, H.1
Fukuda, Y.2
Murata, K.3
Kimura, A.4
-
34
-
-
0031782969
-
Cell polarity and morphogenesis in budding yeast
-
Kevin, M., and S. Michael. 1998. Cell polarity and morphogenesis in budding yeast. Annu. Rev. Microbiol. 52:687-744.
-
(1998)
Annu. Rev. Microbiol.
, vol.52
, pp. 687-744
-
-
Kevin, M.1
Michael, S.2
-
35
-
-
0026733242
-
Structural basis of the intrasteric regulation of myosin light chain kinases
-
Knighton, D. R., R. B. Pearson, J. M. Sowadski, A. R. Means, E. L. F. Ten, S. S. Taylor, and B. E. Kemp. 1992. Structural basis of the intrasteric regulation of myosin light chain kinases. Science 258:130-135.
-
(1992)
Science
, vol.258
, pp. 130-135
-
-
Knighton, D.R.1
Pearson, R.B.2
Sowadski, J.M.3
Means, A.R.4
Ten, E.L.F.5
Taylor, S.S.6
Kemp, B.E.7
-
36
-
-
0033560707
-
Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2
-
Kobayashi, T., and P. Cohen. 1999. Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2. Biochem. J. 339:319-328.
-
(1999)
Biochem. J.
, vol.339
, pp. 319-328
-
-
Kobayashi, T.1
Cohen, P.2
-
37
-
-
0029143388
-
Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase
-
Kohn, A. D., K. S. Kovacina, and R. A. Roth. 1995. Insulin stimulates the kinase activity of RAC-PK, a pleckstrin homology domain containing ser/thr kinase. EMBO J. 14:4288-4295.
-
(1995)
EMBO J.
, vol.14
, pp. 4288-4295
-
-
Kohn, A.D.1
Kovacina, K.S.2
Roth, R.A.3
-
38
-
-
0027465942
-
The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum
-
Kohno, K., K. Normington, J. Sambrook, M. J. Gething, and K. Mori. 1993. The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Mol. Cell. Biol. 13:877-890.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 877-890
-
-
Kohno, K.1
Normington, K.2
Sambrook, J.3
Gething, M.J.4
Mori, K.5
-
39
-
-
0032103445
-
Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants
-
Lanterman, M. M., and J. D. Saba. 1998. Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. Biochem. J. 332:525-531.
-
(1998)
Biochem. J.
, vol.332
, pp. 525-531
-
-
Lanterman, M.M.1
Saba, J.D.2
-
40
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
Lee, M. J., J. R. Van-Brocklyn, S. Thangada, C. H. Liu, A. R. Hand, R. Menzeleev, S. Spiegel, and T. Hla. 1998. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 279:1552-1555.
-
(1998)
Science
, vol.279
, pp. 1552-1555
-
-
Lee, M.J.1
Van-Brocklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
Menzeleev, R.6
Spiegel, S.7
Hla, T.8
-
41
-
-
0026519030
-
Different G1 cyclins control the timing of cell cycle commitment in mother and daughter cells of the budding yeast S. cerevisiae
-
Lew, D. J., N. J. Marini, and S. I. Reed. 1992. Different G1 cyclins control the timing of cell cycle commitment in mother and daughter cells of the budding yeast S. cerevisiae. Cell 69:317-327.
-
(1992)
Cell
, vol.69
, pp. 317-327
-
-
Lew, D.J.1
Marini, N.J.2
Reed, S.I.3
-
42
-
-
0031892088
-
Sphingosine base 1-phosphate phosphatase: A key regulator of sphingolipid metabolism and the stress response
-
Mandala, S. M., R. Thornton, Z. Tu, M. B. Kurtz, J. Nickels, J. Broach, R. Menzeleev, and S. Spiegel. 1998. Sphingosine base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and the stress response. Proc. Natl. Acad. Sci. USA 95:150-155.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 150-155
-
-
Mandala, S.M.1
Thornton, R.2
Tu, Z.3
Kurtz, M.B.4
Nickels, J.5
Broach, J.6
Menzeleev, R.7
Spiegel, S.8
-
43
-
-
0023769704
-
Isolation of a yeast protein kinase gene by screening with a mammalian protein kinase cDNA
-
Maurer, R. A. 1988. Isolation of a yeast protein kinase gene by screening with a mammalian protein kinase cDNA. DNA 7:469-474.
-
(1988)
DNA
, vol.7
, pp. 469-474
-
-
Maurer, R.A.1
-
44
-
-
0024496181
-
Modulation of protein kinase C and diverse cell functions by sphingosine, a pharmacologically interesting compound linking sphingolipids and signal transduction
-
Merrill, A. H. J., and V. L. Stevens. 1989. Modulation of protein kinase C and diverse cell functions by sphingosine, a pharmacologically interesting compound linking sphingolipids and signal transduction. Biochim. Biophys. Acta 1010:131-139.
-
(1989)
Biochim. Biophys. Acta
, vol.1010
, pp. 131-139
-
-
Merrill, A.H.J.1
Stevens, V.L.2
-
45
-
-
0029075192
-
Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin
-
Miyake, Y., Y. Kozutsumi, S. Nakamura, T. Kujita, and T. Kawasaki. 1995. Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin. Biochem. Biophys. Res. Commun. 211: 396-403.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.211
, pp. 396-403
-
-
Miyake, Y.1
Kozutsumi, Y.2
Nakamura, S.3
Kujita, T.4
Kawasaki, T.5
-
46
-
-
0030970048
-
Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene
-
Nagiec, M. M., E. E. Nagiec, J. A. Baltisberger, G. B. Wells, R. L. Lester, and R. C. Dickson. 1997. Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J. Biol. Chem. 272:9809-9817.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9809-9817
-
-
Nagiec, M.M.1
Nagiec, E.E.2
Baltisberger, J.A.3
Wells, G.B.4
Lester, R.L.5
Dickson, R.C.6
-
47
-
-
0027980277
-
The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis
-
Nagiec, M. M., J. A. Baltisberger, G. B. Wells, R. L. Lester, and R. C. Dickson. 1994. The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis. Proc. Natl. Acad. Sci. USA 91:7899-7902.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 7899-7902
-
-
Nagiec, M.M.1
Baltisberger, J.A.2
Wells, G.B.3
Lester, R.L.4
Dickson, R.C.5
-
48
-
-
0030064134
-
Dual roles of sphingolipids in signaling of the escape from and onset of apoptosis in a mouse cytotoxic T-cell line, CTLL-2
-
Nakamura, S., Y. Kozutsumi, Y. Sun, Y. Miyake, T. Fujita, and T. Kawasaki. 1996. Dual roles of sphingolipids in signaling of the escape from and onset of apoptosis in a mouse cytotoxic T-cell line, CTLL-2. J. Biol. Chem. 271: 1255-1257.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 1255-1257
-
-
Nakamura, S.1
Kozutsumi, Y.2
Sun, Y.3
Miyake, Y.4
Fujita, T.5
Kawasaki, T.6
-
49
-
-
0029915925
-
A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae
-
Nickels, J. T., and J. R. Broach. 1996. A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae. Genes Dev. 10:382-394.
-
(1996)
Genes Dev.
, vol.10
, pp. 382-394
-
-
Nickels, J.T.1
Broach, J.R.2
-
50
-
-
0025003424
-
Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation
-
Okazaki, T., A. Bielawska, R. M. Bell, and Y. A. Hannun. 1990. Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation. J. Biol. Chem. 265(26):15823-15831.
-
(1990)
J. Biol. Chem.
, vol.265
, Issue.26
, pp. 15823-15831
-
-
Okazaki, T.1
Bielawska, A.2
Bell, R.M.3
Hannun, Y.A.4
-
51
-
-
0027371722
-
Sphingosine-1-phosphate as a second messenger in cell proliferation induced by PDGF and FCS mitogens
-
Olivera, A., and S. Spiegel. 1993. Sphingosine-1-phosphate as a second messenger in cell proliferation induced by PDGF and FCS mitogens. Nature 365:557-560.
-
(1993)
Nature
, vol.365
, pp. 557-560
-
-
Olivera, A.1
Spiegel, S.2
-
52
-
-
0026697256
-
Sphingolipid long-chain-hase auxotrophs of Saccharomyces cerevisiae: Genetics, physiology, and a method for their selection
-
Pinto, W. J., B. Srinivasan, S. Shepherd, R. A. Dickson, and R. L. Lester. 1992. Sphingolipid long-chain-hase auxotrophs of Saccharomyces cerevisiae: genetics, physiology, and a method for their selection. J. Bacteriol. 174:2565-2574.
-
(1992)
J. Bacteriol.
, vol.174
, pp. 2565-2574
-
-
Pinto, W.J.1
Srinivasan, B.2
Shepherd, S.3
Dickson, R.A.4
Lester, R.L.5
-
53
-
-
0026629282
-
Characterization of the enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: Mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity
-
Pinto, W. J., G. W. Wells, and R. L. Lester. 1992. Characterization of the enzymatic synthesis of sphingolipid long-chain bases in Saccharomyces cerevisiae: mutant strains exhibiting long-chain-base auxotrophy are deficient in serine palmitoyltransferase activity. J. Bacteriol. 174:2575-2581.
-
(1992)
J. Bacteriol.
, vol.174
, pp. 2575-2581
-
-
Pinto, W.J.1
Wells, G.W.2
Lester, R.L.3
-
54
-
-
0032578998
-
Phosphorylation and activation of p70s6k by PDK1
-
Pullen, N., P. B. Dennis, M. Andjelkovic, A. Dufner, S. C. Kozma, B. A. Hemmings, and G. Thomas. 1998. Phosphorylation and activation of p70s6k by PDK1. Science 279:707-710.
-
(1998)
Science
, vol.279
, pp. 707-710
-
-
Pullen, N.1
Dennis, P.B.2
Andjelkovic, M.3
Dufner, A.4
Kozma, S.C.5
Hemmings, B.A.6
Thomas, G.7
-
55
-
-
0030605378
-
Ceramide: An intraceliular mediator of apoptosis and growth suppression
-
Saba, J. D., L. M. Obeid, and Y. A. Hannun. 1996. Ceramide: an intraceliular mediator of apoptosis and growth suppression. Philos. Trans. R. Soc. Lond. B 351:233-240.
-
(1996)
Philos. Trans. R. Soc. Lond. B
, vol.351
, pp. 233-240
-
-
Saba, J.D.1
Obeid, L.M.2
Hannun, Y.A.3
-
56
-
-
0026458406
-
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
-
Schutze, S., K. Potthoff, T. Machleidt, D. Berkovic, K. Wiegmann, and M. Kronke. 1992. TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71:765-776.
-
(1992)
Cell
, vol.71
, pp. 765-776
-
-
Schutze, S.1
Potthoff, K.2
Machleidt, T.3
Berkovic, D.4
Wiegmann, K.5
Kronke, M.6
-
57
-
-
0031007242
-
Evidence against an early signaling role for ceramide in Fas-mediated apoptosis
-
Sillence, D. J., and D. Allan. 1997. Evidence against an early signaling role for ceramide in Fas-mediated apoptosis. Biochem. J. 324:29-32.
-
(1997)
Biochem. J.
, vol.324
, pp. 29-32
-
-
Sillence, D.J.1
Allan, D.2
-
59
-
-
0033053652
-
Sphingosine 1-phosphate: A prototype of a new class of second messengers
-
Spiegel, S. 1999. Sphingosine 1-phosphate: a prototype of a new class of second messengers. J. Leukoc. Biol. 65:341-344.
-
(1999)
J. Leukoc. Biol.
, vol.65
, pp. 341-344
-
-
Spiegel, S.1
-
60
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
-
Stephens, L., K. Anderson, D. Stokoe, H. Erdjument-Bromage, G. F. Painter, A. B. Holmes, P. R. Gaffney, C. B. Reese, F. McCormick, P. Tempst, J. Coadwell, and P. T. Hawkins. 1998. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279:710-714.
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjument-Bromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
Coadwell, J.11
Hawkins, P.T.12
-
61
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
Stokoe, D., L. R. Stephens, T. Copeland, P. R. Gaffney, C. B. Reese, G. F. Painter, A. B. Holmes, F. McCormick, and P. T. Hawkins. 1997. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science 277:567-570.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
62
-
-
0033556558
-
Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine
-
Troncoso, P., S. M. Stepkowski, M. E. Wang, X. Qu, S. C. Chueh, J. Clark, and B. D. Kahan. 1997. Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine. Transplantation 67:145-151.
-
(1997)
Transplantation
, vol.67
, pp. 145-151
-
-
Troncoso, P.1
Stepkowski, S.M.2
Wang, M.E.3
Qu, X.4
Chueh, S.C.5
Clark, J.6
Kahan, B.D.7
-
63
-
-
0030999989
-
Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume
-
Waldegger, S., P. Barth, G. Raber, and F. Lang. 1997. Cloning and characterization of a putative human serine/threonine protein kinase transcriptionally modified during anisotonic and isotonic alterations of cell volume. Proc. Natl. Acad. Sci. USA 94:4440-4445.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4440-4445
-
-
Waldegger, S.1
Barth, P.2
Raber, G.3
Lang, F.4
-
64
-
-
0030844273
-
Fas-induced apoptosis of T cells occurs independently of ceramide generation
-
Watts, J. D., M. Gu, A. J. Polverino, S. D. Patterson, and R. Aebersold. 1997. Fas-induced apoptosis of T cells occurs independently of ceramide generation. Proc. Natl. Acad. Sci. USA 94:7292-7296.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7292-7296
-
-
Watts, J.D.1
Gu, M.2
Polverino, A.J.3
Patterson, S.D.4
Aebersold, R.5
-
65
-
-
0027534990
-
Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum
-
Webster, M. K., L. Goya, Y. Ge, A. C. Maiyar, and G. L. Firestone. 1993. Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol. Cell. Biol. 13:2031-2040.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2031-2040
-
-
Webster, M.K.1
Goya, L.2
Ge, Y.3
Maiyar, A.C.4
Firestone, G.L.5
-
66
-
-
0026049696
-
Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation
-
Zhang, H., N. N. Desai, A. Olivera, T. Seki, G. Brooker, and S. Spiegel. 1991. Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation. J. Cell Biol. 114:155-167.
-
(1991)
J. Cell Biol.
, vol.114
, pp. 155-167
-
-
Zhang, H.1
Desai, N.N.2
Olivera, A.3
Seki, T.4
Brooker, G.5
Spiegel, S.6
-
67
-
-
0025242245
-
CDC6 mRNA fluctuates periodically in the yeast cell cycle
-
Zhou, C., and A. Jong. 1990. CDC6 mRNA fluctuates periodically in the yeast cell cycle. J. Biol. Chem. 265:19904-19909.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 19904-19909
-
-
Zhou, C.1
Jong, A.2
-
68
-
-
0032031519
-
Sphingosine 1-phosphate signaling through the G-protein-coupled receptor Edg-1
-
Zondag, G. C., F. R. Postma, I. V. Etten, I. Verlaan, and W. H. Moolenaar. 1998. Sphingosine 1-phosphate signaling through the G-protein-coupled receptor Edg-1. Biochem. J. 330:605-609.
-
(1998)
Biochem. J.
, vol.330
, pp. 605-609
-
-
Zondag, G.C.1
Postma, F.R.2
Etten, I.V.3
Verlaan, I.4
Moolenaar, W.H.5
|