Construction of a rhamnose mutation in Bacillus anthracis affects adherence to macrophages but not virulence in guinea pigs

Microbial Pathogenesis

Volumn 38, Issue 1, 2005, Pages 1-12

  Bozue, Joel A ^a   Parthasarathy, Narayanan ^a   Phillips, Lawrence R ^b   Cote, Christopher K ^a   Fellows, Patricia F ^a   Mendelson, Itai ^c   Shafferman, Avigdor ^c   Friedlander, Arthur M ^d  

^a U States Army Med Res Inst I   (United States)

^b Developmental Therapeutics Program   (United States)

^c ISRAEL INSTITUTE FOR BIOLOGICAL RESEARCH   (Israel)

^d UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Anthrax; Bacillus anthracis; Exosporium; Rhamnose; rml genes; Spores

Indexed keywords

CYTOCHALASIN D; RHAMNOSE;

ANIMAL EXPERIMENT; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL SPORE; BACTERIAL STRAIN; BACTERIUM ADHERENCE; CHROMOSOME; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE EXPRESSION; GUINEA PIG; MACROPHAGE; MUTATION; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; VIRULENCE; WILD TYPE;

ANIMALS; ANTHRAX; BACILLUS ANTHRACIS; BACTERIAL ADHESION; CYTOCHALASIN D; DISEASE MODELS, ANIMAL; FEMALE; GUINEA PIGS; MACROPHAGES; MULTIGENE FAMILY; MUTATION; RHAMNOSE; SEQUENCE DELETION; SPORES, BACTERIAL; VIRULENCE;

ANIMALIA; ANTHRAX; BACILLUS ANTHRACIS; CAVIA;

EID: 11844251295     PISSN: 08824010     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micpath.2004.10.001     Document Type: Article

References (41)

1. R.J. Manchee, M.G. Broster, J. Melling, R.M. Henstridge, and A.J. Stagg Bacillus anthracis on Gruinard Island Nature 294 1981 254 255
2. J.M. Ross The pathogenesis of anthrax following the administration of spores by the respiratory route J Pathol Bacteriol 73 1957 485 494
3. G. Ruthel, W.J. Ribot, S. Bavari, and T.A. Hoover Time-lapse confocal imaging of development of Bacillus anthracis in macrophages J Infect Dis 189 2004 1313 1316
4. C. Guidi-Rontani, M. Weber-Levy, E. Labruyere, and M. Mock Germination of Bacillus anthracis spores within alveolar macrophages Mol Microbiol 31 1999 9 17
5. P. Gerhardt, and E. Ribi Ultrastructure of the exosporium enveloping spores of Bacillus cereus J Bacteriol 88 1964 1774 1789
6. C. Guidi-Rontani, M. Levy, H. Ohayon, and M. Mock Fate of germinated Bacillus anthracis spores in primary murine macrophages Mol Microbiol 42 2001 931 938
7. L.L. Matz, T.C. Beaman, and P. Gerhardt Chemical composition of exosporium from spores of Bacillus cereus J Bacteriol 101 1970 196 201
8. E. Helgason, O.A. Okstad, D.A. Caugant, H.A. Johansen, A. Fouet, and M. Mock Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis - one species on the basis of genetic evidence Appl Environ Microbiol 66 2000 2627 2630
9. M. Garcia-Patrone, and J.S. Tandecarz A glycoprotein multimer from Bacillus thuringiensis sporangia: dissociation into subunits and sugar composition Mol Cell Biochem 145 1995 29 37
10. L.K. Romana, F.S. Santiago, and P.R. Reeves High level expression and purification of dthymidine diphospho-d-glucose 4,6-dehydratase (rfbB) from Salmonella serovar typhimurium LT2 Biochem Biophys Res Commun 174 1991 846 852
11. R. Munoz, M. Mollerach, R. Lopez, and E. Garcia Molecular organization of the genes required for the synthesis of type 1 capsular polysaccharide of Streptococcus pneumoniae: formation of binary encapsulated pneumococci and identification of cryptic dTDP-rhamnose biosynthesis genes Mol Microbiol 25 1997 79 92
12. I.C. Boels, M.M. Beerthuyzen, M.H. Kosters, M.P. Van Kaauwen, M. Kleerebezem, and W.M. De Vos Identification and functional characterization of the Lactococcus lactis rfb operon, required for dTDP-rhamnose biosynthesis J Bacteriol 186 2004 1239 1248
13. Y. Ma, R.J. Stern, M.S. Scherman, V.D. Vissa, W. Yan, and V.C. Jones Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose Antimicrob Agents Chemother 45 2001 1407 1416
14. M. McNeil, M. Daffe, and P.J. Brennan Evidence for the nature of the link between the arabinogalactan and peptidoglycan of mycobacterial cell walls J Biol Chem 265 1990 18200 18206
15. Y. Ma, F. Pan, and M. McNeil Formation of dTDP-rhamnose is essential for growth of mycobacteria J Bacteriol 184 2002 3392 3395
16. TD. Read, SN. Peterson, N. Tourasse, LW Baillie, IT. Paulsen, and KE. Nelson The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria Nature 423 2003 81 86
17. Glasser P, Kunst F, Arnaud M, Coudart MP, Gonzales W, Hullo MF, et al. Bacillus Subtillis genome project: Cloning and sequencing of the 97 Kb region from 325 degrees to 333 degress. Mol Microbiol. 1993;10:371-84.
18. I. Mendelson, S. Tobery, A. Scorpio, J. Bozue, A. Shafferman, and A.M. Friedlander The NheA component of the non-hemolytic enterotoxin of Bacillus cereus is produced by Bacillus anthracis but is not required for virulence Microb Pathog 37 2004 149 154
19. A. Fox, G.E. Black, K. Fox, and S. Rostovtseva Determination of carbohydrate profiles of Bacillus anthracis and Bacillus cereus including identification of O-methyl methylpentoses by using gas chromatography-mass spectrometry J Clin Microbiol 31 1993 887 894
20. Jansson PE, Kenne L, Liedgren H, Lindberg B, Lonngren J. A Practical Guide to the Methylation Analysis of Carbohydrates. In: Chem Commun (Stockholm); 1976. p. 1-76.
21. P.L. Worsham, and M.R. Sowers Isolation of an asporogenic (spoOA) protective antigen-producing strain of Bacillus anthracis Can J Microbiol 45 1999 1 8
22. F. Kunst, N. Ogasawara, I. Moszer, A.M. Albertini, G. Alloni, and V. Azebedo The complete genome sequence of the gram-positive bacterium Bacillus subtilis Nature 390 1997 249 256
23. A. Fox, G.C. Stewart, L.N. Waller, K.F. Fox, W.M. Harley, and R.L. Price Carbohydrates and glycoproteins of Bacillus anthracis and related bacilli: targets for biodetection J Microbiol Methods 54 2003 143 152
24. N. Kojima, Y. Araki, and E. Ito Structural studies on the acidic polysaccharide of Bacillus cereus AHU 1356 cell walls Eur J Biochem 148 1985 479 484
25. S.J. Todd, A.J. Moir, M.J. Johnson, and A. Moir Genes of Bacillus cereus and Bacillus anthracis encoding proteins of the exosporium J Bacteriol 185 2003 3373 3378
26. P. Sylvestre, E. Couture-Tosi, and M. Mock A collagen-like surface glycoprotein is a structural component of the Bacillus anthracis exosporium Mol Microbiol 45 2002 169 178
27. C. Steichen, P. Chen, J.F. Kearney, and C.L. Turnbough Jr. Identification of the immunodominant protein and other proteins of the Bacillus anthracis exosporium J Bacteriol 185 2003 1903 1910
28. P. Sylvestre, E. Couture-Tosi, and M. Mock Polymorphism in the collagen-like region of the Bacillus anthracis BclA protein leads to variation in exosporium filament length J Bacteriol 185 2003 1555 1563
29. C. Redmond, L.W. Baillie, S. Hibbs, A.J. Moir, and A. Moir Identification of proteins in the exosporium of Bacillus anthracis Microbiology 150 2004 355 363
30. J.M. Daubenspeck, H. Zeng, P. Chen, S. Dong, C.T. Steichen, and N.R. Krishna Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium J Biol Chem 279 2004 30945 30953
31. A. Driks Bacillus subtilis spore coat Microbiol Mol Biol Rev 63 1999 1 20
32. T.J. Leighton, and R.H. Doi The stability of messenger ribonucleic acid during sporulation in Bacillus subtilis J Biol Chem 246 1971 3189 3195
33. S. Bron Plasmids C.R. Harwood Molecular biological methods for Bacillus 1990 Wiley West Sussex, England
34. T. Maniatis, E.F. Fritsch, and J. Sambrook Molecular cloning: a laboratory manual 1982 Cold Spring Harbor Laboratory Cold Spring Harbor, NY
35. B.E. Ivins, S.L. Welkos, G.B. Knudson, and S.F. Little Immunization against anthrax with aromatic compound-dependent (Aro-) mutants of Bacillus anthracis and with recombinant strains of Bacillus subtilis that produce anthrax protective antigen Infect Immun 58 1990 303 308
36. R.M. McCarron, D.K. Goroff, J.E. Luhr, M.A. Murphy, and H.B. Herscowitz Methods for the collection of peritoneal and alveolar macrophages Methods Enzymol 108 1984 274 284
37. I.N. Mbawuike, and H.B. Herscowitz MH-S, a murine alveolar macrophage cell line: morphological, cytochemical, and functional characteristics J Leukoc Biol 46 1989 119 127
38. S. Welkos, A. Friedlander, S. Weeks, S. Little, and I. Mendelson In-vitro characterisation of the phagocytosis and fate of anthrax spores in macrophages and the effects of anti-PA antibody J Med Microbiol 51 2002 821 831
39. B.E. Ivins, P.F. Fellows, and G.O. Nelson Efficacy of a standard human anthrax vaccine against Bacillus anthracis spore challenge in guinea-pigs Vaccine 12 1994 872 874
40. S.F. Little, and G.B. Knudson Comparative efficacy of Bacillus anthracis live spore vaccine and protective antigen vaccine against anthrax in the guinea pig Infect Immun 52 1986 509 512
41. P. Keim, L.B. Price, A.M. Klevytska, K.L. Smith, J.M. Schupp, and R. Okinaka Multiple-locus variable-number tandem repeat analysis reveals genetic relationships within Bacillus anthracis J Bacteriol 182 2000 2928 2936