Formation of dTDP-rhamnose is essential for growth of mycobacteria

Journal of Bacteriology

Volumn 184, Issue 12, 2002, Pages 3392-3395

  Ma, Yufang ^a   Pan, Fei ^a   McNeil, Michael ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RHAMNOSE; THYMIDINE DIPHOSPHATE; THYMIDINE DIPHOSPHATE RHAMNOSE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; GENE INACTIVATION; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; RMLD GENE;

CARBOHYDRATE DEHYDROGENASES; CULTURE MEDIA; MYCOBACTERIUM SMEGMATIS; NUCLEOSIDE DIPHOSPHATE SUGARS; PLASMIDS; RECOMBINATION, GENETIC; THYMINE NUCLEOTIDES;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

EID: 0036267318     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.12.3392-3395.2002     Document Type: Article

References (22)

1. The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar typhimurium, the second enzyme in the dTDP-L-rhamnose pathway
2. Use of a Mycobacterium tuberculosis H37Rv bacterial artificial chromosome library for genome mapping, sequencing, and comparative genomics
3. 13C-NMR analyses
4. Major structural features of the cell wall arabinogalactans of Mycobacterium, Rhodococcus, and Nocardia spp
5. Biological mechanisms involved in the formation of deoxysugars. I. Preparation of thymidine diphosphate glucose labeled specifically in carbon 3
6. RmlC, the third enzyme of dTDP-L-rhamnose pathway, is a new class of epimerase
7. Overexpression, purification, crystallization and preliminary structural study of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD), the fourth enzyme of the dTDP-L-rhamnose synthesis pathway, from Salmonella enterica serovar typhimurium
8. Characterization of dTDP-4-dehydrorhamnose 3,5-epimerase and dTDP-4-dehydrorhamnose reductase, required for dTDP-L-rhamnose biosynthesis in Salmonella enterica serovar typhimurium LT2
9. Use of biotinylated DNA probes in colony hybridization
10. Construction and use of low-copy number T7 expression vectors for purification of problem proteins: Purification of Mycobacterium tuberculosis RmlD and Pseudomonas aeruginosa LasI and RhlI proteins, and functional analysis of purified RhlI
11. Phosphatidylinositol is an essential phospholipid of mycobacteria
12. Drug targeting Mycobacterium tuberculosis cell wall synthesis: Genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose
13. Evidence for the nature of the link between the arabinogalactan and peptidoglycan components of mycobacterial cell walls
14. Location of the mycolyl ester substituent in the cell walls of mycobacteria
15. The mechanism of 6-deoxyhexose synthesis. I. Intramolecular hydrogen transfer catalyzed by deoxythymidine diphosphate D-glucose oxidoreductase
16. Biosynthesis of the linkage region of the mycobacterial cell wall
17. Biosynthesis of thymidine diphosphate L-rhamnose in Escherichia coli K-12
18. Determination that cell wall galactofuran synthesis is essential for growth of mycobacteria
19. Purification to apparent homogeneity and properties of pig kidney L-fucose kinase
20. GDP-L-fucose pyrophosphorylase. Purification, cDNA cloning, and properties of the enzyme
21. Efficient allelic exchange and transposon mutagenesis in Mycobacterium tuberculosis
22. Isolation and characterization of efficient plasmid transformation mutants of Mycobacterium smegmatis