Isoxazolyl-serine-based agonists of peroxisome proliferator-activated receptor: Design, synthesis, and effects on cardiomyocyte differentiation

Journal of the American Chemical Society

Volumn 126, Issue 51, 2004, Pages 16714-16715

  Wei, Zhi Liang ^a   Petukhov, Pavel A ^a   Bizik, Fero ^a   Teixeira, Joaquim Cabral ^b   Mercola, Mark ^b   Volpe, Eugene A ^c   Glazer, Robert I ^c   Willson, Timothy M ^d   Kozikowski, Alan P ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b BURNHAM INSTITUTE   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^d GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 [3 (4 ACETYL 3 HYDROXY 2 PROPYLPHENOXY)PROPOXY]PHENOXY]ACETIC ACID; [2 METHYL 4 [4 METHYL 2 (4 TRIFLUOROMETHYLPHENYL) 5 THIAZOLYLMETHYLTHIO]PHENOXY]ACETIC ACID; FARGLITAZAR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIRINIXIC ACID; RAGAGLITAZAR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; DRUG STABILITY; DRUG SYNTHESIS; HEART MUSCLE CELL; MOUSE; NONHUMAN; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

ANIMALS; CELL DIFFERENTIATION; COMBINATORIAL CHEMISTRY TECHNIQUES; ISOXAZOLES; LIGANDS; MICE; MODELS, MOLECULAR; MYOCYTES, CARDIAC; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; SERINE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 11244309426     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja046386l     Document Type: Article

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