Three-dimensional structure of scorpion toxins: Towards a new model of interaction with potassium channels

Perspectives in Drug Discovery and Design

Volumn 15-16, Issue , 1999, Pages 41-60

  Darbon, H ^a   Blanc, E ^a   Sabatier, J M ^b  

^a Centre National de la Recherche Scientifique   (France)

^b CNRS   (France)

Author keywords

Dipole moment; Neurotoxin; NMR; Potassium channel; Scorpion; Structure

Indexed keywords

AMINO ACID; APAMIN; CHARYBDOTOXIN; KALIOTOXIN; LEIUROTOXIN I; LIGAND; MARGATOXIN; NEUROTOXIN; NOXIUSTOXIN; PEPTIDE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; SCORPION VENOM; VOLTAGE GATED CHANNEL FORMING PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; BINDING KINETICS; CHANNEL GATING; DIPOLE; DISULFIDE BOND; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ION TRANSPORT; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MEMBRANE STRUCTURE; MOLECULAR INTERACTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TOXIN ANALYSIS; TOXIN STRUCTURE;

EID: 0032973257     PISSN: 09282866     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1017070801207     Document Type: Review

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