Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels

Journal of Biological Chemistry

Volumn 279, Issue 53, 2004, Pages 55211-55217

  Huber, Irene G ^a,b   Wappl Kornherr, Edwin ^a   Sinnegger Brauns, Martina J ^a,b   Hoda, Jean Charles ^a   Walter Bastl, Doris ^a   Striessnig, Jörg ^a,c  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c Institut fur Pharmazie   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BRAIN; CALCIUM; MUTAGENESIS; SATURATION (MATERIALS COMPOSITION); SENSITIVITY ANALYSIS; STERILIZATION (CLEANING);

DIHYDROPYRIDINE; DRUG-CHANNEL COMPLEX; PHENYLALKYLAMINE; STERIC MECHANISM;

MUTAGENS;

BARIUM ION; CALCIUM CHANNEL L TYPE; CALCIUM ION; DEVAPAMIL; DIHYDROPYRIDINE DERIVATIVE; GALLOPAMIL; PHENYLALKYLAMINE; VERAPAMIL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; BRAIN MICROSOME; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENANTIOMER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

ANIMALS; BRAIN; CALCIUM; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CARRIER PROTEINS; CELL MEMBRANE; DIHYDROPYRIDINES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GALLOPAMIL; HOMOZYGOTE; IN SITU HYBRIDIZATION; ISRADIPINE; KINETICS; MICE; MICE, TRANSGENIC; MICROSOMES; MODELS, BIOLOGICAL; MUTATION; OOCYTES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, COMPLEMENTARY; STEROID ISOMERASES; TYROSINE; VERAPAMIL; XENOPUS LAEVIS;

ANIMALIA; XENOPUS LAEVIS;

EID: 11244293529     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409008200     Document Type: Article

References (34)

1. Striessnig, J., Grabner, M., Mitterdorfer, J., Hering, S., Sinnegger, M. J., and Glossmann, H. (1998) Trends Pharmacol. Sci. 19, 108-115
2. Hockerman, G. H., Peterson, B. Z., Johnson, B. D., and Catterall, W. A. (1997) Annu. Rev. Pharmacol. Toxicol. 37, 361-396
3. He, M., Bodi, I., Mikala, G., and Schwartz, A. (1997) J. Biol. Chem. 272, 2629-2633
4. Brauns, T., Prinz, H., Kimball, S. D., Haugland, R. P., Striessnig, J., and Glossmann, H. (1997) Biochemistry 36, 3625-3631
5. Peterson, B. Z., Johnson, B. D., Hockerman, G. H., Acheson, M., Scheuer, T., and Catterall, W. A. (1997) J. Biol. Chem. 272, 18752-18758
6. Hering S., Berjukov, S., Aczel, S., and Timin, E. N. (1998) Trends Pharmacol. Sci. 19, 439-443
7. Glossmann, H., and Striessnig, J. (1990) Rev. Physiol. Biochem. Pharmacol. 114, 1-105
8. Oeken, H.-J., Von Nettelbladt, E., Zimmer, M., Flockerzi, V., Ruth, P., and Hofmann, F. (1986) Eur. J. Biochem. 156, 661-667
9. Moebius, F. F., Burrows, G. G., Striessnig, J., and Glossmarin, H. (1993) Mol. Pharmacol. 43, 139-148
10. Sinnegger-Brauns, M. J., Hetzenauer, A., Huber, I. G., Renstrom, E., Wietzorrek, G., Berjukov, S., Cavalli, M., Walter, D., Koschak, A., Waldschutz, R., Hering, S., Bova, S., Rorsman, P., Pongs, O., Singewald, N., and Striessnig, J. J (2004) J. Clin. Invest. 113, 1430-1439
11. Wappl, E., Mitterdorfer, J., Glossmann, H., and Striessnig, J. (2001) J. Biol. Chem. 276, 12730-12735
12. Huber, I., Wappl, E., Herzog, A., Mitterdorfer, J., Glossmann, H., Langer, T., and Striessnig, J. (2000) Biochem. J. 347, 829-836
13. Lowry, O. H., Rosebrough, N. H., Farr, A. L., and Randall, F. J. (1951) J. Biol. Chem. 193, 265-275
14. Liu, X., Rusch, N. J., Striessnig, J., and Sarna, S. K. (2001) Gastroenterology 120, 480-489
15. Pichler, M., Cassidy, T. N., Reimer, D., Haase, H., Kraus, R., Ostler, D., and Striessnig, J. (1997) J. Biol. Chem. 272, 13877-13882
16. Ferry, D. R., Goll, A., Gadow, C., and Glossmann, H. (1984) Naunyn-Schmiedeberg's Arch. Pharmacol. 327, 183-187
17. DeLean, A., Munson, P. J., and Rodbard, D. (1978) Am. J. Physiol. 4, E97-E102
18. Clark, N. C., Nagano, N., Kuenzi, F. M., Jarolimek, W., Huber, I., Walter, D., Wietzorrek, G., Boyce, S., Kullmann, D. M., Striessnig, J., and Seabrook, G. R. (2003) Neuroscience 120, 435-442
19. Mikami, A., Imoto, K., Tanabe, T., Niidome, T., Mori, Y., Takeshima, H., Narumiya, S., and Numa, S. (1989) Nature 340, 230-233
20. Krieg, P. A., and Melton, D. A. (1984) Nucleic Acids Res. 12, 7057-7070
21. Ruth, P., Roehrkasten, A., Biel, M., Bosse, E., Regulla, S., Meyer, H. E., Flockerzi, V., and Hofmann, F. (1989) Science 245, 1115-1118
22. Ellis, S. B., Williams, M. E., Ways, N. R., Brenner, R., Sharp, A. H., Leung, A. T., Campbell, K. P., McKenna, E., Koch, W. J., Hui, A., Schwartz, A., and Harpold, M. M. (1988) Science 241, 1661-1664
23. Reynolds, I. J., Snowman, A. M., and Snyder, S. H. (1986) J. Pharmacol. Exp. Ther. 237, 731-738
24. Hering, S., Savchenko, A., Strübing, C., Lakitsch, M., and Striessnig, J. (1993) Mol. Pharmacol. 43, 820-826
25. Kwan, Y. W., Bangalore, R., Lakitsh, M., Glossmann, H., and Kass, R. S. (1995) J. Mol. Cell Cardiol. 27, 253-262
26. Strübing, C., Hering, S., and Glossmann, H. (1993) Br. J. Pharmacol. 108, 884-891
27. Hescheler, J., Pelzer, D., Trube, G., and Trautwein, W. (1982) Pflügers Arch. 393, 287-291
28. Koschak, A., Reimer, D., Huber, I., Grabner, M., Glossmann, H., Engel, J., and Striessnig, J. (2001) J. Biol. Chem. 276, 22100-22106
29. Hockerman, G. H., Johnson, B. D., Scheuer, T., and Catterall, W. A. (1995) J. Biol. Chem. 270, 22119-22122
30. Dobrev, D., Milde, A. S., Andreas, K., and Ravens, U. (1999) Br. J. Pharmacol. 127, 576-582
31. Ishibashi, H., Yatani, A., and Akaike, N. (1995) Brain Res. 695, 88-91
32. Zhorov, B. S., Folkman, E. V., and Ananthanarayanan, V. S. (2001) Arch. Biochem. Biophys. 393, 22-41
33. Wang, M. C., Collins, R. F., Ford, R. C., Berrow, N. S., Dolphin, A. C., and Kitmitto, A. (2004) J. Biol. Chem. 279, 7159-7168
34. Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B. T., and MacKinnon, R. (2003) Nature 423, 33-41