Analysis of the dihydropyridine receptor site of L-type calcium channels by alanine-scanning mutagenesis

Journal of Biological Chemistry

Volumn 272, Issue 30, 1997, Pages 18752-18758

  Peterson, Blaise Z ^a   Johnson, Barry D ^a   Hockerman, Gregory H ^a   Acheson, Matthew ^a   Scheuer, Todd ^a   Catterall, William A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ALANINE; BARIUM; CALCIUM; CALCIUM ANTAGONIST; CALCIUM CHANNEL; DIHYDROPYRIDINE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM TRANSPORT; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CELL LINE; HUMANS; ISRADIPINE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE MAPPING; PROTEIN STRUCTURE, SECONDARY; RABBITS;

MAMMALIA;

EID: 0030855109     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.30.18752     Document Type: Article

References (59)

1. Hofmann, F., Biel, M., and Flockerzi, V. (1994) Annu. Rev. Neurosci. 17, 399-418
2. Birnbaumer, L., Campbell, K. P., Catterall, W. A., Harpold, M. M., Hofmann, F., Horne, W. A., Mori, Y., Schwartz, A., Snutch, T. P., Tanabe, T., and Tsien, R. W. (1994) Neuron 13, 505-506
3. Dunlap, K., Luebke, J. I., and Turner, T. J. (1995) Trends Neurosci. 18, 89-98
4. Gould, R. J., Murphy, K. M., and Snyder, S. H. (1983) Cold Spring Harbor Symp. Quant. Biol. 48, 355-362
5. Glossmann, H., Ferry, D. R., Goll, A., and Rombusch, M. (1984) J. Cardiovasc. Pharmacol. 6, (Suppl.) 508-621
6. Isom, L. L., De Jongh, K. S., and Catterall, W. A. (1994) Neuron 12, 1183-1194
7. Tanabe, T., Takeshima, H., Mikami, A., Flockerzi, V., Takahashi, H., Kangawa, K., Kojima, M., Matsuo, H., Hirose, T., and Numa, S. (1987) Nature 328, 313-318
8. Mikami, A., Imoto, K., Tanabe, T., Niidome, T., Mori, Y., Takeshima, H., Narumiya, S., and Numa, S. (1989) Nature 340, 230-233
9. Koch, W. J., Ellinor, P. T., and Schwartz, A. (1990) J. Biol. Chem. 265, 17786-17791
10. Snutch, T. P., Tomlinson, W. J., Leonard, J. P., and Gilbert, M. M., (1991) Neuron 7, 45-47
11. Williams, M. E., Feldman, D. H., McCue, A. F., Brenner, R., Velicelebi, G., Ellis, S. B., and Harpold, M. M. (1992) Neuron 8, 71-84
12. Seino, S., Chen, L., Seino, M., Blondel, O., Takeda, J., Johnson, J. H., and Bell, G. I. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 584-588
13. Dubel, S. J., Starr, V. B., Hell, J., Ahlijanian, M. K., Enyeart, J. J., Catterall, W. A., and Snutch, T. P. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 5058-5062
14. Starr, T. V. B., Prystay, W., and Snutch, T. P. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 5621-5625
15. Mori, Y., Friedrich, T., Kim, M.-S., Mikami, A., Nakai, J., Ruth, P., Bosse, E., Hofmann, F., Flockerzi, V., Furuichi, T., Mikoshiba, K., Imoto, K., Tanabe, T., and Numa, S. (1991) Nature 350, 398-402
16. Soong, T. W., Stea, A., Hodson, C. D., Dubel, S. J., Vincent, S. R., and Snutch, T. P. (1993) Science 260, 1133-1136
17. Bechem, M., and Schramm, M. (1987) J. Mol. Cell. Cardiol. 19, 63-75
18. McDonald, T. F., Pelzer, S., Trautwein, W., and Pelzer, D. J. (1994) Physiol. Rev 74, 365-707
19. Kass, R. S., and Arena, J. P. (1989) J. Gen. Physiol. 93, 1109-1127
20. Kass, R. S., Arena, J. P., and Chin, S. (1991) J. Gen. Physiol. 98, 63-75
21. Strubing, C., Hering, S., and Glossmann, H. (1993) Br. J. Pharmacol. 108, 884-891
22. Bangalore, R., Baindur, N., Rutledge, A., Triggle, D. J., and Kass, R. S., (1994) Mol. Pharmacol. 46, 660-666
23. Ferry, D. R., Rombusch, M., Goll, A., and Glossmann, H. (1984) FEBS Lett. 169, 112-167
24. Galizzi, J.-P., Borsotto, M., Barhanin, J., Fosset, M., and Lazdunski, M., (1986) J. Biol. Chem. 261, 1393-1397
25. Sharp, A. H., Imagawa, T., Leung, A. T., and Campbell, K. P. (1987) J. Biol. Chem. 262, 12309-12315
26. Takahashi, M., Seagar, M. J., Jones, J. F., Reber, B. F., and Catterall, W. A. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 5478-5482
27. Vaghy, P. L., Striessnig, J., Miwa, K., Knause, H.-G., Itagaki, K., McKenna, E., Glossmann, H., and Schwartz, A. (1987) J. Biol. Chem. 262, 14337-14342
28. Sieber, M., Nastainczyk, W., Zubor, V., Werner, W., and Hofmann, F. (1987) Eur. J. Biochem. 167, 117-122
29. Hosey, M. M., Barhanin, J., Schmid, A., Vandaele, S., Ptasienski, J., O'Callahan, C., Cooper, C., and Lazdunski, M. (1987) Biochem. Biophys. Res. Commun. 147, 1137-1145
30. Striessnig, J., Murphy, B. J., and Catterall, W. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 10769-10773
31. Nakayama, H., Taki, M., Striessnig, J., Catterall, W. A., and Kanaoka, Y. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 9203-9207
32. Catterall, W. A., and Striessnig, J. (1992) Trends Pharmacol. Sci. 13, 256-262
33. Kalasz, H., Watanabe, T., Yabana, H., Itagaki, K., Naito, K., Nakayama, H., Schwartz, A., and Vaghy, P. L. (1993) FEBS Lett. 331, 177-181
34. Regulla, S., Schneider, T., Nastainczyk, W., Meyer, H. E., and Hofmann, F. (1991) EMBO J. 10, 45-49
35. Grabner, M., Wang, Z. Y., Hering, S., Striessnig, J., and Glossmann, H. (1996) Neuron 16, 207-218
36. Tang, S., Yatani, A., Bahinski, A., Mori, Y., and Schwartz, A. (1993) Neuron 11, 1013-1021
37. Schuster, A., Lacinová, L., Klugbauer, N., Ito, H., Birnbaumer, L., and Hofmann, F. (1996) EMBO J. 15, 2365-2370
38. Peterson, B. Z., Tanada, T. N., and Catterall, W. A. (1996) J. Biol. Chem. 271, 5293-5296
39. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
40. Pragnell, M., Leveille, C. F., Jay, S. D., and Campbell, K. P. (1991) FEBS Lett. 291, 253-257
41. Margolskee, R. F., McHendry-Rinde, B., and Horne, R. (1994) Biotechniques 15, 906-911
42. Blaber, M., Zhang, X. J., and Matthews, B. W. (1993) Science 260, 1637-1640
43. Ragsdale, D. S., Scheuer, T., and Catterall, W. A. (1991) Mol. Pharmacol. 40, 756-765
44. Diochot, S., Richard, S., Baldy-Moulinier, M., Margeot, J., and Valmier, J. (1995) Pflügers Arch. Eur. J. Physiol. 431, 10-19
45. Mitterdorfer, J., Wang, Z., Sinnegger, M. J., Hering, S., Striessnig, J., Grabner, M., and Glossmann, H. (1996) J. Biol. Chem. 271, 30330-30335
46. Zhang, Y., Liang, J.-Y., Haung, S., and Lipscomb, W. N. (1994) J. Mol. Biol. 244, 609-624
47. Kantrowitz, E. R., and Lipscomb, W. N. (1990) Trends Biochem. Sci. 15, 53-59
48. Barford, D., and Johnson, L. N. (1989) Nature 340, 609-616
49. Karlin, A., and Akabas, M. H. (1995) Neuron 15, 1231-1244
50. Tytgat, J., and Hess, P. (1992) Nature 359, 420-423
51. Peterson, B. Z., and Catterall, W. A. (1995) J. Biol. Chem. 270, 18201-18204
52. Mitterdorfer, J., Sinnegger, M. J., Grabner, M., Striessnig, J., and Glossmann, H. (1995) Biochemistry 34, 9350-9355
53. Hockerman, G. H., Johnson, B. D., Scheuer, T., and Catterall, W. A. (1995) J. Biol. Chem. 270, 22119-22122
54. Doring, F., Degtiar, V. E., Grabner, M., Striessnig, J., Hering, S., and Glossmann, H. (1996) J. Biol. Chem. 271, 11745-11749
55. Hering, S., Aczél, S., Grabner, M., Doring, F., Berjukow, S., Mitterdorfer, J., Sinnegger, J., Striessnig, J., Degtiar, V. E., Wang, Z., and Glossmann, H. (1996) J. Biol. Chem. 271, 24471-24475
56. Heschler, J., Pelzer, D., Trube, G., and Trautwein, W. (1982) Pflügers Arch. 393, 287-291
57. Sedyl, K., Kimball, D., and Romanin, C. (1993) Pflügers Arch. 424, 552-554
58. Hering, S., Savchenko, A., Strubing, C., Lakitsch, M., and Striessnig, J. (1993) Mol. Pharmacol. 43, 820-826
59. Hockerman, G. H., Johnson, B. D., Abbott, M. H., Scheuer, T., and Catterall, W. A. (1997) J. Biol. Chem. 272, 18759-18765