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Volumn 36, Issue 6, 2004, Pages 321-326

Effects of intravenous administration of FR122047 (a selective cyclooxygenase 1 inhibitor) and FR188582 (a selective cyclooxygenase 2 inhibitor) on prostaglandin-E2-induced aqueous flare elevation in pigmented rabbits

Author keywords

Aqueous flare; Cyclooxygenase 1; Cyclooxygenase 2; Prostaglandin E2; Rabbit eyes

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DEXAMETHASONE SODIUM PHOSPHATE; DICLOFENAC; FR 122047; FR 188582; GLASS; MESSENGER RNA; PROSTAGLANDIN E2; UNCLASSIFIED DRUG;

EID: 11244289336     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000081634     Document Type: Article
Times cited : (11)

References (22)
  • 5
    • 0036669379 scopus 로고    scopus 로고
    • Distinct function of COX-1 and COX-2
    • Morita I: Distinct function of COX-1 and COX-2. Prostaglandins Lipid Mediat 2002;68-69:165-175.
    • (2002) Prostaglandins Lipid Mediat , vol.68-69 , pp. 165-175
    • Morita, I.1
  • 6
    • 0036669406 scopus 로고    scopus 로고
    • Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2
    • Loftin CD, Tiano HF, Langenbach R: Phenotypes of the COX-deficient mice indicate physiological and pathophysiological roles for COX-1 and COX-2. Prostaglandins Lipid Mediat 2002;68-69:177-185.
    • (2002) Prostaglandins Lipid Mediat , vol.68-69 , pp. 177-185
    • Loftin, C.D.1    Tiano, H.F.2    Langenbach, R.3
  • 7
    • 0037437765 scopus 로고    scopus 로고
    • Advances in the pathophysiology of constitutive and inducible cyclooxygenases: Two enzymes in the spotlight
    • Parente L, Perretti M: Advances in the pathophysiology of constitutive and inducible cyclooxygenases: Two enzymes in the spotlight. Biochem Pharmacol 2003;65:153-159.
    • (2003) Biochem Pharmacol , vol.65 , pp. 153-159
    • Parente, L.1    Perretti, M.2
  • 8
    • 0009761611 scopus 로고
    • Nonsteroidal anti-inflammatory drugs
    • Albert DM, Jacobiec FA (eds): Philadelphia, Saunders Co
    • To K, Abelson MB, Neufeld A: Nonsteroidal anti-inflammatory drugs; in Albert DM, Jacobiec FA (eds): Principles and Practice of Ophthalmology. Philadelphia, Saunders Co, 1994, pp 1022-1027.
    • (1994) Principles and Practice of Ophthalmology , pp. 1022-1027
    • To, K.1    Abelson, M.B.2    Neufeld, A.3
  • 10
    • 0034629473 scopus 로고    scopus 로고
    • The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models
    • Ochi T, Motoyama Y, Goto T: The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models. Eur J Pharmacol 2000;391:49-54.
    • (2000) Eur J Pharmacol , vol.391 , pp. 49-54
    • Ochi, T.1    Motoyama, Y.2    Goto, T.3
  • 11
    • 0036176669 scopus 로고    scopus 로고
    • Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis
    • Ochi T, Goto T: Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. Br J Pharmacol 2002;135:782-788.
    • (2002) Br J Pharmacol , vol.135 , pp. 782-788
    • Ochi, T.1    Goto, T.2
  • 12
    • 0035079724 scopus 로고    scopus 로고
    • The anti-inflammatory effect of FR188582, a highly selective inhibitor of cyclooxygenase-2, with an ulcerogenic sparing effect in rats
    • Ochi T, Sugiyama AY, Ohkubo Y, Sakane K, Tanaka H: The anti-inflammatory effect of FR188582, a highly selective inhibitor of cyclooxygenase-2, with an ulcerogenic sparing effect in rats. Jpn J Pharmacol 2001;85:175-182.
    • (2001) Jpn J Pharmacol , vol.85 , pp. 175-182
    • Ochi, T.1    Sugiyama, A.Y.2    Ohkubo, Y.3    Sakane, K.4    Tanaka, H.5
  • 13
    • 0023712699 scopus 로고
    • New quantitative method to determine protein concentration and cell number in aqueous in vivo
    • Sawa M, Tsurimaki Y, Tsuru T, Shimizu H: New quantitative method to determine protein concentration and cell number in aqueous in vivo. Jpn J Ophthalmol 1988;32:132-142.
    • (1988) Jpn J Ophthalmol , vol.32 , pp. 132-142
    • Sawa, M.1    Tsurimaki, Y.2    Tsuru, T.3    Shimizu, H.4
  • 14
    • 0034775498 scopus 로고    scopus 로고
    • Constitutive expression and localization of COX-1 and COX-2 in rabbit iris and ciliary body
    • Damm J, Rau T, Maihofner C, Pahl A, Brune K: Constitutive expression and localization of COX-1 and COX-2 in rabbit iris and ciliary body. Exp Eye Res 2001;72:611-621.
    • (2001) Exp Eye Res , vol.72 , pp. 611-621
    • Damm, J.1    Rau, T.2    Maihofner, C.3    Pahl, A.4    Brune, K.5
  • 16
    • 0029888972 scopus 로고    scopus 로고
    • Selective inhibition of cyclooxygenase-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis
    • Anderson GD, Hauser SD, McGarity KL, Bremer ME, Isakson PC, Gregory SA: Selective inhibition of cyclooxygenase-2 reverses inflammation and expression of COX-2 and interleukin 6 in rat adjuvant arthritis. J Clin Invest 1996;97:2672-2679.
    • (1996) J Clin Invest , vol.97 , pp. 2672-2679
    • Anderson, G.D.1    Hauser, S.D.2    McGarity, K.L.3    Bremer, M.E.4    Isakson, P.C.5    Gregory, S.A.6
  • 19
    • 0029809863 scopus 로고    scopus 로고
    • Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: Evidence for post-transcriptional regulation
    • Ristimaki A, Narko K, Hla T: Down-regulation of cytokine-induced cyclo-oxygenase-2 transcript isoforms by dexamethasone: Evidence for post-transcriptional regulation. Biochem J 1996;318:325-331.
    • (1996) Biochem J , vol.318 , pp. 325-331
    • Ristimaki, A.1    Narko, K.2    Hla, T.3
  • 21
    • 0035400078 scopus 로고    scopus 로고
    • Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells
    • Stichtenoth DO, Thoren S, Bian H, Peters-Golden M, Jakobsson PJ, Crofford LJ: Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells. J Immunol 2001;167:469-474.
    • (2001) J Immunol , vol.167 , pp. 469-474
    • Stichtenoth, D.O.1    Thoren, S.2    Bian, H.3    Peters-Golden, M.4    Jakobsson, P.J.5    Crofford, L.J.6
  • 22
    • 0030832266 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids
    • Goppelt-Struebe M: Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids. Biochem Pharmacol 1997;53:1389-1395.
    • (1997) Biochem Pharmacol , vol.53 , pp. 1389-1395
    • Goppelt-Struebe, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.