Disease-Associated Qualitative and Quantitative Trait Loci in Proteoglycan-Induced Arthritis and Collagen-Induced Arthritis

American Journal of the Medical Sciences

Volumn 327, Issue 4, 2004, Pages 188-195

  Glant, Tibor T ^a,b   Adarichev, V A ^a   Nesterovitch, A B ^a   Szanto, S ^a,c   Oswald, J P ^b   Jacobs, J J ^a   Firneisz, G ^a,d   Zhang, J ^a,b   Finnegan, A ^b   Mikecz, K ^a,b  

^a RUSH UNIVERSITY   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF DEBRECEN   (Hungary)

^d SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

Arthritis; Collagen induced arthritis; Genome screen; Proteoglycan induced arthritis; Rheumatoid arthritis

Indexed keywords

COLLAGEN; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CHROMOSOME 10; CHROMOSOME 17; CHROMOSOME 3; CHROMOSOME 5; CONFERENCE PAPER; CYTOKINE PRODUCTION; DISEASE MODEL; DISEASE SEVERITY; FEMALE; GENETIC CROSS; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN LOCALIZATION; QUALITATIVE ANALYSIS; QUANTITATIVE TRAIT LOCUS; RHEUMATOID ARTHRITIS; T LYMPHOCYTE; X CHROMOSOME;

EID: 11144358268     PISSN: 00029629     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000441-200404000-00004     Document Type: Conference Paper

References (47)

1. Ollier WER, Worthington J. New horizons in rheumatoid arthritis genetics. J Rheumatol 1997;24:193.
2. John S, Hajeer A, Marlow A, et al. Investigation of candidate disease susceptibility genes in rheumatoid arthritis: principles and strategies. J Rheumatol 1997;24:199-201.
3. Cornelis F, Faure S, Martinez M, et al. New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study. Proc Natl Acad Sci U S A 1998;95:10746-50.
4. Shiozawa S, Hayashi S, Tsukamoto Y, et al. Identification of the gene loci that predispose to rheumatoid arthritis. Int Immunol 1998;10:1891-5.
5. Bali D, Gourley S, Kostyu DD, et al. Genetic analysis of multiplex rheumatoid arthritis families. Genes Immun 1999;1:28-36.
6. Ota M, Katsuyama Y, Kimura A, et al. A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region. Genomics 2001;71:263-70.
7. MacKay K, Eyre S, Myerscough A, Laval S et al. Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis Rheum 2002;46:632-9.
8. Kawahito Y, Cannon GW, Gulko PS, et al. Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: evidence for genetic factors common to multiple autoimmune diseases. J Immunol 1998;161:4411-9.
9. Cannon GW, Openshaw S, Clayton F, et al. Adjuvant arthritis in rats: Susceptibility to arthritis induced by Mycobacterium butyricum and Mycobacterium tuberculosis. Transplant Proc 1999;31:1590-1.
10. Lorentzen JC, Glaser A, Jacobsson L, et al. Identification of rat susceptibility loci for adjuvant-oil-induced arthritis. Proc Natl Acad Sci U S A 1998;95:6383-7.
11. Jansson ÅM, Jacobsson L, Luthman H, et al. Susceptibility to oil-induced arthritis is linked to Oia2 on chromosome 4 in a DA(DA × PVG. 1AV1) backcross. Transplant Proc 1999;31:1597-9.
12. Vingsbo-Lundberg C, Nordquist N, Olofsson P, et al. Genetic control of arthritis onset, severity and chronicity in a model for rheumatoid arthritis in rats. Nat Genet 1998;20:401-4.
13. Remmers EF, Longman RE, Du Y, et al. A genome scan localizes five non-MHC loci controlling collagen- induced arthritis in rats. Nat Genet 1996;14:82-5.
14. 2 crosses. Immunogenetics 1998;48:335-8.
15. Wilder RL, Griffiths MM, Remmers EF, et al. Localization in rats of genetic loci regulating susceptibility to experimental erosive arthritis and related autoimmune diseases. Transplant Proc 1999;31:1585-8.
16. Gulko PS, Kawahito Y, Remmers EF, et al. Identification of a new non-major histocompatibility complex genetic locus on chromosome 2 that controls disease severity in collagen-induced arthritis in rats. Arthritis Rheum 1998;41:2122-31.
17. Jirholt J, Cook A, Emahazion T, et al. Genetic linkage analysis of collagen-induced arthritis in the mouse. Eur J Immunol 1998;28:3321-8.
18. McIndoe RA, Bohlman B, Chi E, et al. Localization of non-MHC collagen-induced arthritis susceptibility loci in DBA/1j mice. Proc Natl Acad Sci U S A 1999;96:2210-4.
19. Yang H-T, Jirholt J, Svensson L, et al. Identification of genes controlling collagen-induced arthritis in mice: striking homology with susceptibility loci previously identified in the rat. J Immunol 1999;163:2916-21.
20. Griffiths MM, Wang J, Joe B, et al. Identification of four new quantitative trait loci regulating arthritis severity and one new quantitative trait locus regulating autoantibody production in rats with collagen-induced arthritis. Arthritis Rheum 2000;43:1278-89.
21. Joe B, Remmers EF, Dobbins DE, et al. Genetic dissection of collagen-induced arthritis in chromosome 10 quantitative trait locus speed congenic rats: evidence for more than one regulatory locus and sex influences. Immunogenetics 2000;51:930-44.
22. Otto JM, Cs-Szabó G, Gallagher J, et al. Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis. Arthritis Rheum 1999;42:2524-31.
23. Otto JM, Chandrasekaran R, Vermes C, et al. A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis. J Immunol 2000;165:5278-86.
24. Adarichev VA, Bárdos T, Christodoulou S, et al. Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis. Immunogenetics 2002;54:184-92.
25. Adarichev VA, Valdez JC, Bárdos T, et al. Combined autoimmune models of arthritis reveal shared and independent qualitative (binary) and quantitative trait loci. J Immunol 2003;170:2283-92.
26. Vyse TJ, Todd JA. Genetic analysis of autoimmune disease. Cell 1996;85:311-8.
27. Becker KG, Simon RM, Bailey-Wilson JE, et al. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc Natl Acad Sci U S A 1998;95:9979-84.
28. Griffiths MM, Encinas JA, Remmers EF, et al. Mapping autoimmunity genes. Curr Opin Immunol 1999;11:689-700.
29. Lin JP, Cash JM, Doyle SZ, et al. Familial clustering of rheumatoid arthritis with other autoimmune diseases. Hum Genet 1998;103:475-82.
30. Seldin MF, Amos CI, Ward R, et al. The genetics revolution and the assault on rheumatoid arthritis. Arthritis Rheum 1999;42:1071-9.
31. Jawaheer D, Seldin MF, Amos CI, et al. A genome-wide screen in multiplex rheumatoid arthritis families suggests genetic overlap with other autoimmune diseases. Am J Hum Genet 2001;68:927-36.
32. Glant TT, Mikecz K, Arzoumanian A, et al. Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology. Arthritis Rheum 1987;30:201-12.
33. Mikecz K, Glant TT, Poole AR. Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan. Arthritis Rheum 1987;30:306-18.
34. Glant TT, Cs-Szabó G, Nagase H, et al. Progressive poly-arthritis induced in BALB/c mice by aggrecan from human osteoarthritic cartilage. Arthritis Rheum 1998;41:1007-18.
35. Glant TT, Bárdos T, Vermes C, et al. Variations in susceptibility to proteoglycan-induced arthritis and spondylitis among C3H substrains of mice. Evidence of genetically acquired resistance to autoimmune disease. Arthritis Rheum 2001;44:682-92.
36. Trentham DE, Townes AS, Kang AH. Autoimmunity to type II collagen: an experimental model of arthritis. J Exp Med 1977;146:857-68.
37. Courtenay JS, Dallman MJ, Dayan AD, et al. Immunization against heterologous type II collagen induces arthritis in mice. Nature 1980;282:666-8.
38. Catchart ES, Hayes KC, Gonnerman W, et al. Experimental arthritis in a nonhuman primate. Clin Res 1984;32:462a.
39. Wooley PH, Luthra HS, Stuart JM, et al. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J Exp Med 1981;154:688-700.
40. Bárdos T, Mikecz K, Finnegan A, et al. T and B cell recovery in arthritis adoptively transferred to SCID mice: Antigen-specific activation is required for restoration of autopathogenic CD4+ Th1 cells in a syngeneic system. J Immunol 2002;168:6013-21.
41. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning: a laboratory manual. New York: Cold Spring Harbor Laboratory Press; 1989.
42. Manly KF, Cudmore RH Jr, Meer JM. Map Manager QTX, cross-platform software for genetic mapping. Mamm Genome 2001;12:930-2.
43. Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995;11:241-7.
44. Schweizer RC, van Kessel-Welmers BAC, Warringa RAJ, et al. Mechanisms involved in eosinophil migration. Platelet-activating factor-induced chemotaxis and interleukin-5-induced chemokinesis are mediated by different signals. J Leukoc Biol 1996;59:347-56.
45. Glant TT, Mikecz K, Thonar EJMA, et al. Immune responses to cartilage proteoglycans in inflammatory animal models and human diseases. In: Woessner JF, Howell DS, editors. Cartilage Degradation: Basic and Clinical Aspects. New York: Marcel Dekker; 1992. p. 435-73.
46. Johansson AC, Sundler M, Kjellen P, et al. Genetic control of collagen-induced arthritis in a cross with NOD and C57BL/10 mice is dependent on gene regions encoding complement factor 5 and FcgammaRIIb and is not associated with loci controlling diabetes. Eur J Immunol 2001;31:1847-56.
47. Glant TT, Finnegan A, Mikecz K. Proteoglycan-induced arthritis: immune regulation, cellular mechanisms, and genetics. Crit Rev Immunol 2003;23:199-250.