메뉴 건너뛰기




Volumn 101, Issue 4, 2003, Pages 1316-1323

Autocrine-paracrine VEGF loops potentiate the maturation of megakaryocytic precursors through Flt1 receptor

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; GROWTH FACTOR; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 0037441869     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-07-2184     Document Type: Article
Times cited : (133)

References (56)
  • 1
    • 0029035985 scopus 로고
    • Thrombopoietin: The primary regulator of platelet production
    • Kaushansky K. Thrombopoietin: the primary regulator of platelet production. Blood. 1995;86:419-431.
    • (1995) Blood , vol.86 , pp. 419-431
    • Kaushansky, K.1
  • 2
    • 0029837329 scopus 로고    scopus 로고
    • Effect of thrombopoietin on the development of megakaryocytes and platelets: An ultrastructural analysis
    • Zucker-Franklin D, Kaushansky K. Effect of thrombopoietin on the development of megakaryocytes and platelets: an ultrastructural analysis. Blood. 1996;88:1632-1638.
    • (1996) Blood , vol.88 , pp. 1632-1638
    • Zucker-Franklin, D.1    Kaushansky, K.2
  • 3
    • 0033969732 scopus 로고    scopus 로고
    • Polyploidy: Occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system
    • Zimmet J, Ravid K, Polyploidy: occurrence in nature, mechanisms, and significance for the megakaryocyte-platelet system. Exp Hematol. 2000;28:3-16.
    • (2000) Exp Hematol , vol.28 , pp. 3-16
    • Zimmet, J.1    Ravid, K.2
  • 4
    • 0030982911 scopus 로고    scopus 로고
    • Ultrastructure of platelet formation by human megakaryocytes culture with the Mpl ligand
    • Cramer EM, Norol F, Guichard J, et al. Ultrastructure of platelet formation by human megakaryocytes culture with the Mpl ligand. Blood. 1997;89:2336-2346.
    • (1997) Blood , vol.89 , pp. 2336-2346
    • Cramer, E.M.1    Norol, F.2    Guichard, J.3
  • 6
    • 0032101536 scopus 로고    scopus 로고
    • Thrombopoietin requires additional megakaryocyte-active cytokines for optimal ex vivo expansion of megakaryocyte precursor cells
    • Williams J-L, Pipia G-G, Datta N-S, Long M-W. Thrombopoietin requires additional megakaryocyte-active cytokines for optimal ex vivo expansion of megakaryocyte precursor cells. Blood. 1998;91:4118-4126.
    • (1998) Blood , vol.91 , pp. 4118-4126
    • Williams, J.-L.1    Pipia, G.-G.2    Datta, N.-S.3    Long, M.-W.4
  • 7
    • 0035353204 scopus 로고    scopus 로고
    • SDF-1α increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells
    • Guerriero R, Mattia G, Testa U, et al. SDF-1α increases polyploidization of megakaryocytes generated by human hematopoietic progenitor cells. Blood. 2001;97:2587-2595.
    • (2001) Blood , vol.97 , pp. 2587-2595
    • Guerriero, R.1    Mattia, G.2    Testa, U.3
  • 8
    • 0028276818 scopus 로고
    • Distinct roles of erythropoietin, insulin-like growth factor 1, and stem cell factor in the development of erythroid progenitor cells
    • Muta K, Krantz S-B, Bondurant M-C, Wickrema A. Distinct roles of erythropoietin, insulin-like growth factor 1, and stem cell factor in the development of erythroid progenitor cells. J Clin Invest. 1994;94:34-43.
    • (1994) J Clin Invest , vol.94 , pp. 34-43
    • Muta, K.1    Krantz, S.-B.2    Bondurant, M.-C.3    Wickrema, A.4
  • 9
    • 0032890051 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Molecular and biological aspect
    • Ferrara N. Vascular endothelial growth factor: molecular and biological aspect. Curr Top Microbiol Immunol. 1999;237:1-30.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 1-30
    • Ferrara, N.1
  • 10
    • 0032907687 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) and its receptors
    • Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J. 1999;13:9-22.
    • (1999) FASEB J , vol.13 , pp. 9-22
    • Neufeld, G.1    Cohen, T.2    Gengrinovitch, S.3    Poltorak, Z.4
  • 11
    • 0034650802 scopus 로고    scopus 로고
    • Regulation of angiogenesis via vascular endothelial growth factor receptors
    • Veikkola T, Karkkainen M, Claesson-Welsh L, Alitalo K. Regulation of angiogenesis via vascular endothelial growth factor receptors. Cancer Res. 2000;60:203-212.
    • (2000) Cancer Res , vol.60 , pp. 203-212
    • Veikkola, T.1    Karkkainen, M.2    Claesson-Welsh, L.3    Alitalo, K.4
  • 12
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • Gale N-W, Yancopoulos G-D. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev. 1999;13:1055-1066.
    • (1999) Genes Dev , vol.13 , pp. 1055-1066
    • Gale, N.-W.1    Yancopoulos, G.-D.2
  • 13
    • 0032890336 scopus 로고    scopus 로고
    • Structure, expression and receptor-binding properties of placenta growth factor (PIGF)
    • Persico M-G, Vincenti V, Di Palma T. Structure, expression and receptor-binding properties of placenta growth factor (PIGF). Curr Top Microbiol Immunol. 1999;237:31-40.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 31-40
    • Persico, M.-G.1    Vincenti, V.2    Di Palma, T.3
  • 14
    • 0033604614 scopus 로고    scopus 로고
    • Signaling via vascular endothelial growth factor receptors
    • Petrova P-V, Makinen T, Alitalo K. Signaling via vascular endothelial growth factor receptors. Exp Cell Res. 1999;253:117-130.
    • (1999) Exp Cell Res , vol.253 , pp. 117-130
    • Petrova, P.-V.1    Makinen, T.2    Alitalo, K.3
  • 15
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D-W, Cachlanes G, Kuang W-J, Goeddel D, Ferrara N. Vascular endothelial growth factor is a secreted angiogenic mitogen. Science. 1989;246:1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.-W.1    Cachlanes, G.2    Kuang, W.-J.3    Goeddel, D.4    Ferrara, N.5
  • 16
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature. 1992;359:843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 17
    • 0029021660 scopus 로고
    • Role of the Flt1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G-J, Rossant J, Gertsenstein M, Breitman M-L. Role of the Flt1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature. 1995;376:66-70.
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.-J.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.-L.4
  • 18
    • 0030004485 scopus 로고    scopus 로고
    • Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene
    • Ferrara N, Carver-Moore K, Chen H, et al. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature. 1996;380:439-442.
    • (1996) Nature , vol.380 , pp. 439-442
    • Ferrara, N.1    Carver-Moore, K.2    Chen, H.3
  • 19
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P, Ferreira V, Breler G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 1996;380:435-439.
    • (1996) Nature , vol.380 , pp. 435-439
    • Carmeliet, P.1    Ferreira, V.2    Breler, G.3
  • 20
    • 0029006696 scopus 로고
    • Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
    • Shalaby F, Rossant J, Yamaguchi TP, et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature. 1995;376:62-66.
    • (1995) Nature , vol.376 , pp. 62-66
    • Shalaby, F.1    Rossant, J.2    Yamaguchi, T.P.3
  • 21
    • 0030831104 scopus 로고    scopus 로고
    • A requirement for Flk-1 in primitive and definitive hematopoiesis and vasculogenesis
    • Shalaby F, Ho J, Stanford WL, et al. A requirement for Flk-1 in primitive and definitive hematopoiesis and vasculogenesis. Cell. 1997;89:981-990.
    • (1997) Cell , vol.89 , pp. 981-990
    • Shalaby, F.1    Ho, J.2    Stanford, W.L.3
  • 22
    • 0028284689 scopus 로고
    • Isolation of tyrosine kinase related genes expressed in the early hematopoietic system
    • Larsson-Blomberg L, Dzierzak E. Isolation of tyrosine kinase related genes expressed in the early hematopoietic system. FEBS Lett. 1994;348:119-125.
    • (1994) FEBS Lett , vol.348 , pp. 119-125
    • Larsson-Blomberg, L.1    Dzierzak, E.2
  • 23
    • 0028880305 scopus 로고
    • Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation
    • Katoh O, Tauchi H, Kawalshi K, Kimura A, Satow Y. Expression of the vascular endothelial growth factor (VEGF) receptor gene, KDR, in hematopoietic cells and inhibitory effect of VEGF on apoptotic cell death caused by ionizing radiation. Cancer Res. 1995;55:5687-5692.
    • (1995) Cancer Res , vol.55 , pp. 5687-5692
    • Katoh, O.1    Tauchi, H.2    Kawalshi, K.3    Kimura, A.4    Satow, Y.5
  • 24
    • 0031892785 scopus 로고    scopus 로고
    • Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells
    • Oyama T, Rau S, Ishida T, et al. Vascular endothelial growth factor affects dendritic cell maturation through the inhibition of nuclear factor-kappa B activation in hemopoietic progenitor cells. J. Immunol. 1998;160:1224-1232.
    • (1998) J Immunol , vol.160 , pp. 1224-1232
    • Oyama, T.1    Rau, S.2    Ishida, T.3
  • 25
    • 0033520341 scopus 로고    scopus 로고
    • KDR receptor: A key marker defining hematopoietic stem cells
    • Ziegler B-L, Valtieri M, Almeida Porada G, et al. KDR receptor: a key marker defining hematopoietic stem cells. Science. 1999;285:1553-1558.
    • (1999) Science , vol.285 , pp. 1553-1558
    • Ziegler, B.-L.1    Valtieri, M.2    Almeida Porada, G.3
  • 26
    • 12944253116 scopus 로고    scopus 로고
    • + cells identifies a population of functional endothelial precursors
    • + cells identifies a population of functional endothelial precursors. Blood. 2000;95:952-958.
    • (2000) Blood , vol.95 , pp. 952-958
    • Peichev, M.1    Naiyer, A.-J.2    Pereira, D.3
  • 27
    • 0036838561 scopus 로고    scopus 로고
    • Identification of the hemangioblast in post-natal life
    • Pelosi E, Valtieri M, Coppola S, et al. Identification of the hemangioblast in post-natal life. Blood. 2002;100:3203-3208.
    • (2002) Blood , vol.100 , pp. 3203-3208
    • Pelosi, E.1    Valtieri, M.2    Coppola, S.3
  • 28
    • 0032427654 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor (VEGF) and placenta-derived growth factor (PIGF) in regulating human haemopoietic cell growth
    • Ratajczak MZ, Ratajczak J, Machalinski B, et al. Role of vascular endothelial growth factor (VEGF) and placenta-derived growth factor (PIGF) in regulating human haemopoietic cell growth. Br J Haematol. 1998;103:969-979.
    • (1998) Br J Haematol , vol.103 , pp. 969-979
    • Ratajczak, M.Z.1    Ratajczak, J.2    Machalinski, B.3
  • 29
    • 0035254646 scopus 로고    scopus 로고
    • Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocytemacrophages in humans
    • Sawano A, Iwai S, Sakurai Y, et al. Flt-1, vascular endothelial growth factor receptor 1, is a novel cell surface marker for the lineage of monocytemacrophages in humans. Blood. 2001;97:785-790.
    • (2001) Blood , vol.97 , pp. 785-790
    • Sawano, A.1    Iwai, S.2    Sakurai, Y.3
  • 30
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via VEGF receptor flt-1
    • Barleon B, Sozzani S, Zhou D, Welch H-A, Mantovani A, Marme D. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via VEGF receptor flt-1. Blood. 1999;87:3336-3343.
    • (1999) Blood , vol.87 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3    Welch, H.-A.4    Mantovani, A.5    Marme, D.6
  • 31
    • 0031029290 scopus 로고    scopus 로고
    • Constitutive production and thrombininduced release of vascular endothelial growth factor by human megakaryocytes and platelets
    • Möhle R, Green D, Moore MAS, Nachman RL, Rafii S. Constitutive production and thrombininduced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc Natl Acad Sci U S A. 1997;94:663-668.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 663-668
    • Möhle, R.1    Green, D.2    Moore, M.A.S.3    Nachman, R.L.4    Rafii, S.5
  • 32
    • 0035313555 scopus 로고    scopus 로고
    • Erythroblasts are a source of angiogenic factors
    • Tordjman R, Delaire S, Plouet J, et al. Erythroblasts are a source of angiogenic factors. Blood. 2001;97:1968-1974.
    • (2001) Blood , vol.97 , pp. 1968-1974
    • Tordjman, R.1    Delaire, S.2    Plouet, J.3
  • 33
    • 0032512811 scopus 로고    scopus 로고
    • Thrombopoietin stimulates VEGF release from c-mpl-expressing cell lines and haemopoietic progenitors
    • Bobik R, Hong Y, Breier G, Martin JF, Erusalimsky JD. Thrombopoietin stimulates VEGF release from c-mpl-expressing cell lines and haemopoietic progenitors. FEBS Lett. 1998;423:10-14.
    • (1998) FEBS Lett , vol.423 , pp. 10-14
    • Bobik, R.1    Hong, Y.2    Breier, G.3    Martin, J.F.4    Erusalimsky, J.D.5
  • 34
    • 10344230473 scopus 로고    scopus 로고
    • Expression of growth factor receptors in unilineage differentiation culture of purified hematopoietic progenitors
    • Testa U, Fossati C, Samoggla P, et al. Expression of growth factor receptors in unilineage differentiation culture of purified hematopoietic progenitors. Blood. 1996;88:3391-3406.
    • (1996) Blood , vol.88 , pp. 3391-3406
    • Testa, U.1    Fossati, C.2    Samoggla, P.3
  • 35
    • 0029000894 scopus 로고
    • Modulation of retinoblastoma gene in normal adult hematopoiesis: Peak expression and functional role in advanced erythroid differentiation
    • Condorelli GL, Testa U, Valtieri M, et al. Modulation of retinoblastoma gene in normal adult hematopoiesis: peak expression and functional role in advanced erythroid differentiation. Proc Natl Acad Sci U S A. 1995;92:4808-4812.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4808-4812
    • Condorelli, G.L.1    Testa, U.2    Valtieri, M.3
  • 36
    • 0029134556 scopus 로고
    • Multi-level effects of FLT3 ligand on human hematopoiesis: Expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors
    • Gabbianelli M, Pelosi E, Montesoro E, Testa U, Peschle C. Multi-level effects of FLT3 ligand on human hematopoiesis: expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors. Blood. 1995;86:1661-1670.
    • (1995) Blood , vol.86 , pp. 1661-1670
    • Gabbianelli, M.1    Pelosi, E.2    Montesoro, E.3    Testa, U.4    Peschle, C.5
  • 37
    • 0028892291 scopus 로고
    • Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture
    • Guerriero R, Testa U, Gabbianelli M, et al. Unilineage megakaryocytic proliferation and differentiation of purified hematopoietic progenitors in serum-free liquid culture. Blood. 1995;86:3725-3736.
    • (1995) Blood , vol.86 , pp. 3725-3736
    • Guerriero, R.1    Testa, U.2    Gabbianelli, M.3
  • 39
    • 0030042748 scopus 로고    scopus 로고
    • + bone marrow cells) are enriched with megakaryocytes expressing CD4
    • + bone marrow cells) are enriched with megakaryocytes expressing CD4. Blood. 1996;87:1353-1360.
    • (1996) Blood , vol.87 , pp. 1353-1360
    • Dolzhanskiy, A.1    Basch, R.S.2    Karpatkin, S.3
  • 40
    • 0023947268 scopus 로고    scopus 로고
    • Kinetics of hemopoiesis in a hypoxic culture
    • Ishidowa Y, Ito T. Kinetics of hemopoiesis in a hypoxic culture. Eur J Hematol. 1998;40:126-129.
    • (1998) Eur J Hematol , vol.40 , pp. 126-129
    • Ishidowa, Y.1    Ito, T.2
  • 41
    • 0026543489 scopus 로고
    • Reduced oxygen tension increases hematopoiesis in long-term culture of human stem and progenitor cells from cord blood and bone marrow
    • Keller MR, Bender JG, Miller WM, Papoutsakis ET. Reduced oxygen tension increases hematopoiesis in long-term culture of human stem and progenitor cells from cord blood and bone marrow. Exp Hematol. 1992;20:264-270.
    • (1992) Exp Hematol , vol.20 , pp. 264-270
    • Keller, M.R.1    Bender, J.G.2    Miller, W.M.3    Papoutsakis, E.T.4
  • 42
    • 0033214848 scopus 로고    scopus 로고
    • Multilineage embryonic hematopoiesis requires hypoxic ARNT activity
    • Adelman D-M, Maltepe E, Simon M-C. Multilineage embryonic hematopoiesis requires hypoxic ARNT activity. Genes Dev. 1999;13:2478-2483.
    • (1999) Genes Dev , vol.13 , pp. 2478-2483
    • Adelman, D.-M.1    Maltepe, E.2    Simon, M.-C.3
  • 43
    • 0037071389 scopus 로고    scopus 로고
    • The molecular and cellular biology of thrombopoietin: The primary regulator of platelet production
    • Kaushansky K, Drachman JG. The molecular and cellular biology of thrombopoietin: the primary regulator of platelet production. Oncogene. 2002;21:3359-3367.
    • (2002) Oncogene , vol.21 , pp. 3359-3367
    • Kaushansky, K.1    Drachman, J.G.2
  • 45
    • 0026604637 scopus 로고
    • Comparison of platelet production in two strains of mice with different modal megakaryocyte DNA ploidies after exposure to hypoxia
    • McDonald TP, Cottrel MB, Steward SA, et al. Comparison of platelet production in two strains of mice with different modal megakaryocyte DNA ploidies after exposure to hypoxia. Exp Hematol. 1992;20:51-56.
    • (1992) Exp Hematol , vol.20 , pp. 51-56
    • McDonald, T.P.1    Cottrel, M.B.2    Steward, S.A.3
  • 46
    • 0017360042 scopus 로고
    • Biphasic thrombocytopenic response to severe hypobaric hypoxia
    • Jackson CW, Edwards CC. Biphasic thrombocytopenic response to severe hypobaric hypoxia. Br J Haematol. 1977;35:233-244.
    • (1977) Br J Haematol , vol.35 , pp. 233-244
    • Jackson, C.W.1    Edwards, C.C.2
  • 47
    • 0016259287 scopus 로고
    • Role of iron as a regulator of thrombopoiesis
    • Karpatkin S, Garg SK, Freedman ML. Role of iron as a regulator of thrombopoiesis. Am J Med. 1974;57:521-525.
    • (1974) Am J Med , vol.57 , pp. 521-525
    • Karpatkin, S.1    Garg, S.K.2    Freedman, M.L.3
  • 48
    • 0017851098 scopus 로고
    • Effects of shortterm hypoxia on platelet counts in mice
    • McDonald TP, Cottrel MB, Clift R. Effects of shortterm hypoxia on platelet counts in mice. Blood. 1978;51:165-175.
    • (1978) Blood , vol.51 , pp. 165-175
    • McDonald, T.P.1    Cottrel, M.B.2    Clift, R.3
  • 49
    • 7144227927 scopus 로고    scopus 로고
    • Increase in serum vascular endothelial growth factor levels during altitude training
    • Asano M, Kaneoka K, Nomura T, et al. Increase in serum vascular endothelial growth factor levels during altitude training. Acta Physiol Scand. 1998;162:455-459.
    • (1998) Acta Physiol Scand , vol.162 , pp. 455-459
    • Asano, M.1    Kaneoka, K.2    Nomura, T.3
  • 50
    • 0033211461 scopus 로고    scopus 로고
    • The effect of high altitude on platelet counts, thrombopoietin and erythropoetin levels in young Bolivian airmen visiting the Andes
    • Hudson JG, Bowen AL, Navia P, et al. The effect of high altitude on platelet counts, thrombopoietin and erythropoetin levels in young Bolivian airmen visiting the Andes. Int J Biometeorol. 1999;43:85-90.
    • (1999) Int J Biometeorol , vol.43 , pp. 85-90
    • Hudson, J.G.1    Bowen, A.L.2    Navia, P.3
  • 51
    • 0030866934 scopus 로고    scopus 로고
    • Sustained activation of the extracellular signal-regulated kinase/mitogen-activated pathway is required for megakaryocytic differentiation of K562
    • Racke F-K, Lewandowska K, Guoeli S, Goldfarb N-J. Sustained activation of the extracellular signal-regulated kinase/mitogen-activated pathway is required for megakaryocytic differentiation of K562. Biol Chem. 1997;272:23366-23370.
    • (1997) Biol Chem , vol.272 , pp. 23366-23370
    • Racke, F.-K.1    Lewandowska, K.2    Guoeli, S.3    Goldfarb, N.-J.4
  • 52
    • 0033566712 scopus 로고    scopus 로고
    • Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: Role in endomitosis
    • Rojnuckarin P, Drachman J-G, Kaushansky K. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis. Blood. 1999;94:1273-1282.
    • (1999) Blood , vol.94 , pp. 1273-1282
    • Rojnuckarin, P.1    Drachman, J.-G.2    Kaushansky, K.3
  • 53
    • 0033199619 scopus 로고    scopus 로고
    • Megakaryocyte growth and development factorinduced proliferation and differentiation are regulated by the mitogen-activated protein kinase pathway in primitive cord blood hematopoietic progenitors
    • Fichelson S, Freyssinier JM, Picard F, et al. Megakaryocyte growth and development factorinduced proliferation and differentiation are regulated by the mitogen-activated protein kinase pathway in primitive cord blood hematopoietic progenitors. Blood. 1999;94:1601-1613.
    • (1999) Blood , vol.94 , pp. 1601-1613
    • Fichelson, S.1    Freyssinier, J.M.2    Picard, F.3
  • 54
    • 0037182861 scopus 로고    scopus 로고
    • VEGF regulates hematopoietic stem cell survival by an internal autocrine loop mechanism
    • Geraber HP, Malik AK, Solar GP, et al. VEGF regulates hematopoietic stem cell survival by an internal autocrine loop mechanism. Nature. 2002;417:954-958.
    • (2002) Nature , vol.417 , pp. 954-958
    • Geraber, H.P.1    Malik, A.K.2    Solar, G.P.3
  • 55
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • Gabrilovich D, Ishida T, Oyama T, et al. Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood. 1998;92:4150-4166.
    • (1998) Blood , vol.92 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3
  • 56
    • 0035821293 scopus 로고    scopus 로고
    • Vascular endothelial growth and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells
    • Hattori K, Dias S, Heissig B, et al. Vascular endothelial growth and angiopoietin-1 stimulate postnatal hematopoiesis by recruitment of vasculogenic and hematopoietic stem cells. J Exp Med. 2001;9:1005-1014.
    • (2001) J Exp Med , vol.9 , pp. 1005-1014
    • Hattori, K.1    Dias, S.2    Heissig, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.