Neuropsychiatric disorders and GABA

Japanese Journal of Neuropsychopharmacology

Volumn 24, Issue 5, 2004, Pages 265-271

  Fujimori, Sayumi ^a   Yoneda, Yukio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Depression; Epilepsy; GABA; Schizophrenia

Indexed keywords

2 OXOGLUTARIC ACID; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; ALCOHOL; ALKALINE PHOSPHATASE; AMINE OXIDASE (FLAVIN CONTAINING); ANTIDEPRESSANT AGENT; AUTOANTIBODY; BACLOFEN; BENZODIAZEPINE; COCAINE; DIAMORPHINE; DIAZEPAM; GLUTAMATE DECARBOXYLASE; GLUTAMIC ACID; GROWTH HORMONE; MESSENGER RNA; MUSCIMOL; NICOTINE; PYRIDOXAL 5 PHOSPHATE; RECEPTOR SUBUNIT; SEROTONIN UPTAKE INHIBITOR; SUCCINATE SEMIALDEHYDE DEHYDROGENASE; SUCCINIC SEMIALDEHYDE; TRICARBOXYLIC ACID; VIGABATRIN;

ADDICTION; ALCOHOLISM; ANIMAL MODEL; AUTOIMMUNE DISEASE; BLOOD BRAIN BARRIER; BRAIN FUNCTION; DEPRESSION; DRUG DEPENDENCE; EPILEPSY; EPILEPTOGENESIS; HUMAN; MENTAL DISEASE; NEUROLOGIC DISEASE; NEUROTRANSMISSION; NONHUMAN; PREPULSE INHIBITION; RAT; REVIEW; SCHIZOPHRENIA; STIFF MAN SYNDROME; WITHDRAWAL SYNDROME;

CENTRAL NERVOUS SYSTEM DISEASES; GAMMA-AMINOBUTYRIC ACID; HUMANS; MENTAL DISORDERS; SIGNAL TRANSDUCTION;

EID: 11144260088     PISSN: 13402544     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (52)

1. Addolorato, G., Caputo, F., Capristo, E., Colombo, G., Gessa, G. L. and Gasbarrini, G. (2000) Ability of baclofen in reducing alcohol craving and intake. II. Preliminary clinical evidence. Alcohol Clin Exp Res, 24: 67-71.
2. Addolorato, G., Caputo, F., Capristo, E., Domenicali, M., Bernardi, M., Janiri, L., Agabio, R., Colombo, G., Gessa, G. L. and Gasbarrini, G. (2002) Baclofen efficacy in reducing alcohol craving and intake: A preliminary double-blind randomized controlled study. Alcohol Alcohol, 37: 504-508.
3. Akbarian, S., Kim, J. J., Potkin, S, G., Hagman, J. O., Tafazzoli, A., Bunney, W. E. Jr. and Jones, E. G. (1995) Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics. Arch Gen Psychiatry, 52: 258-266.
4. B receptor in γ-vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine. Synapse, 31: 151-153.
5. Awapara, J., Landua, A. J., Fuerst, R. and Seale, B. (1950) Free γ-aminobutyric acid in brain. J Biol Chem, 187: 35-39.
6. A receptor binding in superficial layers of cingulate cortex in schizophrenics. J Neurosci, 12: 924-929.
7. Berrettini, W. H., Umberkoman-Wiita, B., Nurnberger, J. I. Jr., Vogel, W. H., Gershon, E. S. and Post, R. M. (1982) Platelet GABA-transaminase in affective illness. Psychiatry Res, 7: 255-260.
8. Berrettini, W. H., Nurnberger J. I. Jr., Hare, T. A., Simmons-Alling, S., Gershon, E. S. and Post, R. M. (1983) Reduced plasma and CSF γ-aminobutyric acid in affective illness: Effect of lithium carbonate. Biol Psychiatry, 18: 185-194.
9. B receptor agonists reduce operant ethanol self-administration and enhance ethanol sedation in C57BL/6J mice. Psychopharmacology (Berl), 174: 358-366.
10. Bjork, J. M., Moeller, F. G., Kramer, G. L., Kram, M., Suris, A., Rush, A. J. and Petty F. (2001) Plasma GABA levels correlate with aggressiveness in relatives of patients with unipolar depressive disorder. Psychiatry Res, 101: 131-136.
11. Cohen, L. (1966) Stiff-man syndrome. Two patients treated with diazepam. JAMA, 195: 222-224.
12. Colombo, G., Agabio, R., Carai, M. A., Lobina, C., Pani, M., Reali, R., Addolorato, G. and Gessa, G. L. (2000) Ability of baclofen in reducing alcohol intake and withdrawal severity. I. Preclinical evidence. Alcohol Clin Exp Res, 24: 58-66.
13. B receptor agonists baclofen and CGP 44532 prevent acquisition of alcohol drinking behaviour in alcohol-preferring rats. Alcohol Alcohol, 37: 499-503.
14. Corrigall, W. A., Coen, K. M., Adamson, K. L., Chow, B. L. and Zhang, J. (2000) Response of nicotine self-administration in the rat to manipulations μ-opioid and γ-aminobutyric acid receptors in the ventral tegmental area. Psychopharmacology (Berl), 149: 107-114.
15. B receptor agonists for the treatment of drug addiction: A review of recent findings. Drug Alcohol Depend, 65: 209-220.
16. B) receptor positive modulator GS39783 (N,N′-dicyclopentyl-2-methylsulfanyl-5-nito-pyrimidine-4,6-diamine): Anxiolytic-like activity without side-effects associated with baclofen or benzodiazepines. J Pharmacol Exp Ther, 310: 952-963.
17. Daoust, M., Saligaut, C., Lhuintre, J. P., Moore, N., Flipo, J. L. and Boismare, F. (1987) GABA transmission, but not benzodiazepine receptor stimulation, modulates ethanol intake by rats. Alcohol, 4: 469-472.
18. A receptors in mediating the effects of alcohol in the central nervous system. J Psychiatry Neurosci, 28: 263-274.
19. A receptor subunit peptide levels in rat cortex during chronic ethanol consumption and withdrawal. J Neurochem, 69: 126-130.
20. Dinkel, K., Meinck, H. M., Jury, K. M., Karges, W. and Richter, W. (1998) Inhibition of γ-aminobutyric acid synthesis by glutamic acid decarboxylase autoantibodies in stiff-man syndrome. Ann Neurol, 44: 194-201.
21. B receptor agonist, is hedonically neutral and reduces cocaine-induced enhancement of reward. Neuropharmacology, 42: 626-632.
22. During, M. J., Ryder, K. M. and Spencer, D. D. (1995) Hippocampal GABA transporter function in temporal-lobe epilepsy. Nature, 376: 174-177.
23. Ellis, T. M. and Atkinson, M. A. (1996) The clinical significance of an autoimmune response against glutamic acid decarboxylase. Nat Med, 2: 148-153.
24. Gerner, R. and Hare, T. (1981) CSF GABA in normal subjects and patients with depression, schizophrenia, mania, and anorexia nervosa. Am J Psychiatry, 138: 1098-1101.
25. Gold, B. I., Bowers, M. B. Jr., Roth, R. H. and Sweeney, D. W. (1980) GABA levels in CSF of patients with psychiatric disorders. Am J Psychiatry, 137: 362-364.
26. A receptors in the acute and chronic effects of ethanol. Psychopharmacology (Berl), 139: 2-19.
27. Halbreich, U., Petty, F., Yonkers, K., Kramer, G. L., Rush, A. J. and Bibi, K. W. (1996) Low plasma γ-aminobutyric acid levels during the late luteal phase of women with premenstrual dysphoric disorder. Am J Psychiatry, 153: 718-720.
28. 3H]muscimol binding sites increased in autopsied brains of chronic schizophrenics. Life Sci, 40: 259-266.
29. Homanics, G. E., DeLorey, T. M., Firestone, L. L., Quinlan, J. J., Handforth, A., Harrison, N. L., Krasowski, M. D., Rick, C. E., Korpi, E. R., Makela, R., Brilliant, M. H., Hagiwara, N., Ferguson, C., Snyder, K. and Olsen, R. W. (1997) Mice devoid of γ-aminobutyrate type A receptor β3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Proc Natl Acad Sci USA, 94: 4143-4148.
30. Kaiya, H., Namba, M., Yoshida, H. and Nakamura, S. (1982) Plasma glutamate decarboxylase activity in neuropsychiatry. Psychiatry Res, 6: 335-343.
31. Kasa, K., Otsuki, S., Yamamoto, M., Sato, M., Kuroda, H. and Ogawa, N. (1982) Cerebrospinal fluid γ-aminobutyric acid and homovanillic acid in depressive disorders. Biol Psychiatry, 17: 877-883.
32. Levy, L. M., Dalakas, M. C. and Floeter, M. K. (1999) The stiffperson syndrome: An autoimmune disorder affecting neurotransmission of γ-aminobutyric acid. Ann Intern Med, 13: 522-530.
33. Ling, W., Shoptaw, S. and Majewska, D. (1998) Baclofen as a cocaine anti-craving medication: A preliminary clinical study. Neuropsychopharmacology, 18: 403-404.
34. B agonist baclofen in patients with major depression. Psychoneuroendocrinology, 16: 475-479.
35. A receptor gene expression by ethanol in the rat hippocampus versus cerebral cortex. J Neurochem, 70: 1160-1166.
36. Mhatre, M. C. and Ticku, M. K. (1992) Chronic ethanol administration alters γ-aminobutyric acid A receptor gene expression. Mol Pharmacol, 42: 415-422.
37. A receptor a subunits reveal that chronic alcohol treatment down-regulates a-subunit expression in rat brain regions. J Neurochem, 61: 1620-1625.
38. Mizukami, K., Sasaki, M., Ishikawa, M., Iwakiri, M., Hidaka, S., Shiraishi, H. and Iritani, S. (2000) Immunohistochemical localization of γ-aminobutyric acid B receptor in the hippocampus of subjects with schizophrenia. Neurosci Lett, 283: 101-104.
39. B receptor in the entorhinal cortex and inferior temporal cortex of schizophrenic brain. Prog Neuropsychopharmacol Biol Psychiatry, 26: 393-396.
40. Petty, F. and Sherman, A. D. (1984) Plasma GABA levels in psychiatric illness. J Affect Disord, 6: 131-138.
41. Petty, F., Fulton, M., Moeller, F. G., Kramer, G., Wilson, L., Fraser, K. and Isbell, P. (1993) Plasma γ-aminobutyric acid (GABA) is low in alcoholics. Psychopharmacol Bull, 29: 277-281.
42. Petty, F., Trivedi, M. H., Fulton, M. and Rush, A. J. (1995) Benzodiazepines as antidepressants: Does GABA play a role in depression? Biol Psychiatry, 38: 578-591.
43. Prevett, M. C., Brown, P. and Duncan, J. S. (1997) Improvement of stiff-man syndrome with vigabatrin. Neurology, 48: 1133-1134.
44. Roberts, E., and Frankel, S. (1950) γ-Aminobutyric acid in brain: Its formation from glutamic acid. J Biol Chem, 187: 55-63.
45. Solimena, M. and De Camilli, P. (1991) Autoimmunity to glutamic acid decarboxylase (GAD) in Stiff-Man syndrome and insulin-dependent diabetes mellitus. Trends Neurosci, 14: 452-457.
46. Stork, O., Ji, F. Y., Kaneko, K., Stork, S., Yoshinobu, Y., Moriya, T., Shibata, S. and Obata K. (2000) Postnatal development of a GABA deficit and disturbance of neural functions in mice lacking GAD65. Brain Res, 865: 45-58.
47. B receptor function. J Pharmacol Exp Ther, 307: 322-330.
48. Volk, D. W., Austin, M. C., Pierri, J. N., Sampson, A. R. and Lewis, D. A. (2000) Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical γ-aminobutyric acid neurons in subjects with schizophrenia. Arch Gen Psychiatry, 57: 237-245.
49. A receptor β3 subunit in primary cultured rat hippocampus cells. Neuropsychopharmacology, 26: 415-421.
50. 6. Nat Gene, 11: 45-51.
51. Xi, Z. X. and Stein, E. A. (1999) Baclofen inhibits heroin self-administration behavior and mesolimbic dopamine release. J Pharmacol Exp Ther, 290: 1369-1374.
52. Xi, Z. X. and Stein, E. A. (2000) Increased mesolimbic GABA concentration blocks heroin self-administration in the rat. J Pharmacol Exp Ther, 294: 613-619.