Synthesis of a small library of 3-(carboranylalkyl)thymidines and their biological evaluation as substrates for human thymidine kinases 1 and 2

Journal of Medicinal Chemistry

Volumn 45, Issue 18, 2002, Pages 4018-4028

  Al Madhoun, Ashraf S ^a   Johnsamuel, Jayaseharan ^b   Yan, Junhua ^b   Ji, Weihua ^b   Wang, Jianghai ^a   Zhuo, Jin Cong ^b   Lunato, Anthony J ^b   Woollard, Jeffrey E ^c   Hawk, Andrew E ^c   Cosquer, Guirec Y ^b   Blue, Thomas E ^c   Eriksson, Staffan ^a   Tjarks, Werner ^b  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b OHIO STATE UNIVERSITY   (United States)

^c Ohio State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THYMIDINE DERIVATIVE; THYMIDINE KINASE; THYMIDINE KINASE 1; THYMIDINE KINASE 2; UNCLASSIFIED DRUG;

ARTICLE; DNA LIBRARY; ENZYME ACTIVITY; LINEAR ENERGY TRANSFER; PHOSPHORYLATION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SOLUBILITY;

BORON COMPOUNDS; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; THYMIDINE; THYMIDINE KINASE;

EID: 0037194616     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020047q     Document Type: Article

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