Diabetes mellitus in coronary artery surgery: Therapeutic strategies in the light of recent studies

Thoracic and Cardiovascular Surgeon

Volumn 52, Issue 6, 2004, Pages 349-355

  Lauruschkat, Achim Helmut ^a,b   Ennker, J ^a  

^a Heart Institute Lahr/Baden   (Germany)

^b Heart Institute Lahr/Baden   (Germany)

Author keywords

Coronary artery bypass grafting; Coronary artery disease; Diabetes mellitus; Mortality; Myocardial infarction; Risk factors

Indexed keywords

ABCIXIMAB; ANTICOAGULANT AGENT;

BLOOD CLOTTING; BLOOD PRESSURE REGULATION; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; CORONARY ARTERY SURGERY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; DIAGNOSTIC PROCEDURE; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; HEART MUSCLE REVASCULARIZATION; HEMODYNAMICS; HUMAN; ISCHEMIC HEART DISEASE; KIDNEY FAILURE; METABOLIC REGULATION; NEUROLOGIC DISEASE; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE; SURGICAL TECHNIQUE;

ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; BLOOD GLUCOSE; BLOOD PRESSURE; CLINICAL TRIALS; CORONARY ARTERY BYPASS; CORONARY DISEASE; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; DIABETIC NEUROPATHIES; FIBRINOLYTIC AGENTS; HUMANS; LIPID METABOLISM;

EID: 10844281848     PISSN: 01716425     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2004-821322     Document Type: Review

References (90)

1. Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12 year cardiovascular mortality for men screened in the multiple risk factor intervention trial. Diabetes Care 1993; 16: 434-444
2. Lowe LP, Liu K, Greenland O, Metzger BE, Dyer AR, Stamler J. Diabetes, asymptomatic hyperglycemia, and 22-year mortality in black and white men. Diabetes Care 1997; 20:163-169
3. Harris MI, Hadden WC, Knowler WC, Bennet PH. Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in US Population aged 20-74 years. Diabetes 1987; 36: 523-534
4. Kannel WB, McGee DL. Diabetes and cardiovascular risk factors: the Frarhingham Study. Circulation 1979; 59: 8-13
5. Cohen Y, Raz I, Merin G, Mozes B. Comparison of factors associated with 30-day mortality after coronary artery bypass grafting in patients with versus without diabetes mellitus. Am J Cardiol 1998; 81: 7-11
6. Morris JJ, Smith LR, Jones RH et al. Influence of diabetes and mammary artery grafting on survival after coronary bypass. Circulation 1991; 84: 275-284
7. Weintraub WS, Wenger NK, Jones EL, Craver JM, Guyton RA. Changing clinical characteristics of coronary surgery patients. Differences between men and women. Circulation 1993; 88: 79-86
8. Jacoby RM, Nesto RW. Acute myocardial infarction in the diabetic patient: pathophysiology, clinical course and prognosis. J Am Coll Cardiol 1992; 20: 736-744
9. Karlson BW, Herlitz J, Hjalmarson A. Prognosis of acute myocardial infarction in diabetic and non-diabetic patients. Diabet Med 1993; 10: 449-454
10. Zarich S, Waxman S, Freeman RT, Mittleman M, Hegarty P, Nesto RW. Effect of autonomic nervous system dysfunction on the circadian pattern of myocardial ischemia in diabetes mellitus. J Am Coll Cardiol 1994;24:956-962
11. Nasher PJ Jr, Brown RE, Oskarsson H, Winniford MD, Rossen JD. Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation 1995; 91: 635-640
12. Nitenberg A, Valensi P, Sachs R, Dali M, Aptecar E, Attali JR. Impairment of coronary vascular reserve and ACh-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function. Diabetes 1993; 42:1017-1025
13. Huszka M, Kaplar M, Rejto L et al. The association of reduced endothelium derived relaxing factor-NO production with endothelial damage and increased in-vivo platelet activation in patients with diabetes mellitus. Thromb Res 1997; 86:173-180
14. Diederich D, Skopec J, Diederich A, Dai FX. Endothelial dysfunction in mesenteric resistance arteries of diabetic rats: role of free radicals. Am J Physiol 1994; 266: H1153-1161
15. Mayhan WG. Impairment of endothelium-dependent dilatation of cerebral arterioles during diabetes mellitus. Am J Physiol 1989; 256: H621-625
16. 2. Am J Physiol 1989; 257: H1327-1333
17. Lee TS, Mac Gregor LC, Fluharty SJ, King GL. Differential regulation of protein kinase C and (Na,K)-adenosine triphosphatase activities by elevated glucose levels in retinal capillary endothelial cells. J Clin Invest 1989; 83: 90-94
18. Gawler D, Milligan G, Spiegel AM, Unson CG, Houslay MD. Abolition of the expression of inhibitory guanine nucleotide regulatory protein G1 activity in diabetes. Nature 1987; 327: 229-232
19. Abaci A, Oguzhan A, Kahraman S et al. Effect of diabetes mellitus on formation of coronary collateral vessels. Circulation 1999; 99: 2239-2242
20. Malmberg K, Norhammar A, Wedel H, Ryden L. Glycometabolic state at admission: important risk marker of mortality in conventionally treated patients with diabetes mellitus and acute myocardial infarction: long-term results from the Diabetes and Insulin-Glucose Infusion in Acute Myocardial Infarction (DIGAMI) study. Circulation 1999; 99: 2626-2632
21. Malmberg K, Herlitz J, Hjalmarsson A, Ryden L. Effects of metropolol on mortality and late infarction in diabetics with suspected acute myocardial infarction: retrospective data from two large scale studies: Eur Heart J 1989; 10: 423-428
22. The Bypass Angioplasty Revascularization Investigation (BARI) Investigators. Influence of diabetes on 5-year mortality and morbidity in a randomized trial comparing CABG and PTCA in patients with multi-vessel disease: the Bypass Angioplasty Revascularization Investigation. Circulation 1997; 96: 1761-1769
23. Abizaid A, Kornowski R, Mintz G et al. The influence of diabetes mellitus on acute and late clinical outcomes following coronary stent implantation. J Am Coll Cardiol 1998; 32: 584-589
24. Thourani VH, Weintraub WS, Stein B et al. Influence of diabetes mellitus on early and late outcome after coronary artery bypass grafting. Ann Thorac Surg 1999; 67: 1045-1052
25. The Bypass Angioplasty Revascularization Investigation (BARI) Investigators. Comparison of bypass surgery with angioplasty in patients with multivessel disease. N Engl J Med 1996; 335: 217-225
26. Lawrie GM, Morris GC Jr, Glaeser DH. Influence of diabetes mellitus on the results of coronary bypass surgery. Follow-up of 122 diabetic patients ten to 15 years after surgery. JAMA 1986; 256: 2967-2971
27. The Bypass Angioplasty Revascularization Investigation (BARI) Investigators. Protocoll for the bypass angioplasty revascularization investigation. Circulation 1991; 84: V1-V27
28. Brooks MM, Jones RH, Bach RG et al. Predictors of mortality and mortality from cardiac causes in the Bypass Angioplasty Revascularization Investigation (BARI) randomized trial and registry. Circulation 2000; 101: 2682-2689
29. The Bypass Angioplasty Revascularization Investigation (BARI) Investigators. Seven-year outcome in the Bypass Angioplasty Revascularization Investigation (BARI) by treatment and diabetic status. J Am Coll Cardiol 2000; 35: 1130-1133
30. Niles NW, McGrath PD, Malenka D et al. Northern New England Cardiovascular Disease Study Group. Survival of patients with diabetes and multivessel coronary artery disease after surgical or percutaneous revascularization: results of a large regional prospective study. J Am Coll Cardiol 2001; 37: 1016-1018
31. Abizaid A, Costa MA, Centemero M et al. Clinical and economic impact of diabetes mellitus on percutaneous and surgical treatment of multivessel coronary disease patients. Insights from the Arterial Revascularization Therapy Study (ARTS) trial. Circulation 2001; 104: 533-538
32. Serruys PW, Unger F, Sousa JE et al. Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N Engl J Med 2001; 344: 1117-1124
33. Marso SP, Lincoff AM, Ellis SG et al., for the EPISTENT Investigators. Optimizing the percutaneous interventional outcomes for patients with diabetes mellitus. Results of the EPISTENT (Evaluation of Platelet IIb/IIIa Inhibitor for Stenting Trial) diabetic substudy. Circulation 1999; 100: 2477-2484
34. Kuntz RE. Importance of considering atherosclerosis progression when choosing a coronary revascularization strategy: the diabetes-percutaneous transluminal coronary angioplasty dilemma. Circulation 1999; 99: 847-851
35. Detre KM, Lombardero MS, Brooks MM et al. The effect of previous coronary-artery bypass surgery on the prognosis of patients with diabetes who have acute myocardial infarction. N Engl J Med 2000; 342: 989-997
36. Alderman EL. Late benefit of coronary surgery on mortality from myocardial infarction. Circulation 1991; 83: 1087-1089
37. Peduzzi P, Detre K, Murphy ML, Thomsen J, Hultgren H, Takaro T. Ten-year incidence of myocardial infarction and prognosis after infarction. Department of Veterans Affairs Cooperative Study of Coronary Artery Bypass Surgery. Circulation 1991; 83: 747-755
38. Grossi EA, Esposito R, Harris LJ et al. Sternal wound infections and use of internal mammary artery grafts. J Thorac Cardiovasc Surg 1991; 102: 342-346; discussion 346-347
39. He GW, Ryan WH, Acuff TE et al. Risk factors for operative mortality and sternal wound infection in bilateral internal mammary artery grafting. J Thorac Cardiovasc Surg 1994; 107: 196-202
40. Calafiore AM, Vitolla G, laco AL et al. Bilateral internal mammary artery grafting: midterm results of pedicled versus skeletonized conduits. Ann Thorac Surg 1999; 67: 1637-1642
41. Wendler O, Hennen B, Demertzis S et al. Complete arterial revascularization in multivessel coronary artery disease with 2 conduits (skeletonized grafts and T grafts). Circulation 2000; 102: 79III-83III
42. Borger MA, Cohen G, Buth KJ et al. Multiple arterial grafts. Radial versus right internal thoracic arteries. Circulation 1998; 98:117-13; discussion II13-14
43. Stewart RD, Campos CT, Jennings B, Lollis SS, Levitsky S, Lahey SJ. Predictors of 30-day hospital readmission after coronary artery bypass. Ann Thorac Surg 2000; 70: 169-174
44. Ennker J, Rehm I, Horst P, Hausmann H, Hetzer R. HbA1c als Infektions-Prädiktor in der Koronarchirurgie bei Patienten mit Diabetes mellitus. Thorac Cardiovasc Surg 1994; 42: 50
45. Braxton JH, Marrin CAS, McGrath PD et al. Mediastinitis and long-term survival after coronary artery bypass graft surgery. Ann Thorac Surg 2000; 70: 2004-2007
46. Zerr KJ, Furnary AP, Grunkemeier GL et al. Glucose control lowers the risk of wound infection in diabetics after open heart operation. Ann Thorac Surg 1997; 63: 356-361
47. Furnary AP, Zerr KJ, Grunkemeier GL, Starr A. Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures. Ann Thorac Surg 1999; 67: 352-360
48. Hennessey PJ, Black CT, Andrassy RJ. Nonenzymatic glycosylation of immunoglobulin G impairs complement fixation. J Parenter Enter Nutr 1991; 15: 60-64
49. Black CT, Hennessey PJ, Andrassy RJ. Short-term hyperglycemia depresses immunity through nonenzymatic glycosylation of circulating immunoglobulin. J Trauma 1990; 30: 830-833
50. Bagdade JD, Root RK, Bulger RJ. Impaired leukocyte function in patients with poorly controlled diabetes. Diabetes 1974; 23: 9-15
51. Bagdade JD, Stewart M, Walters E. Impaired granulocyte adherence: a reversible defect in host defence in patients with poorly controlled diabetes. Diabetes 1978; 27: 677-681
52. Sima AA, O'Neil SJ, Naimark D et al. Bacterial phagocytosis and intracellular killing by alveolar macrophages in BB rats. Diabetes 1988; 37: 544-549
53. Mowat A, Baum J. Chemotaxis of polymorphonuclear leukocytes from patients with diabetes mellitus. N Engl J Med 1971; 284: 621-627
54. Nolan CM, Beaty HN, Bagdade JD. Further characterization of the impaired bactericidal function of granulocytes in patients with poorly controlled diabetes. Diabetes 1978; 27: 889-894
55. Davidson NJ, Sowden JM, Fletcher J. Defective phagocytosis in insulin controlled diabetics: evidence for a reaction between glucose and opsonising proteins. J Clin Pathol 1984; 37: 783-786
56. Drachman RH, Root RK, Wood WB Jr. Studies on the effect of experimental nonketotic diabetes mellitus on antibacterial defence. I. Demonstration of a defect in phagocytosis. J Exp Med 1966; 124: 227-240
57. Garcia MJ, McNamara PM, Gordon T, Kannel WB. Morbidity and mortality in diabetics in the Framingham population. Sixteen year follow-up. Diabetes 1974; 23: 105-111
58. Hypertension in Diabetes Study Group. HDS 2: Increased risk of cardio-vascular complications in hypertensive type 2 diabetic patients. J Hypertens 1993; 11: 319-325
59. Hanefeld M, Fischer S, Julius U, Schulze J et al. Risk factors for myocardial infarction and death in newly detected NIDDM: the diabetes intervention study, 11-year follow-up. Diabetologia 1996; 39: 1577-1583
60. Hansson L, Zanchetti A, Carruthers SG et al. Effect of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomised trial. Lancet 1998; 351: 1755-1762
61. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998; 317: 703-713
62. Adler AI, Stratton IM, Neil HA et al. Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study. BMJ 2000; 321: 412-419
63. Haffner SM, Letho S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in non-diabetic subjects with and without prior myocardial infarction. N Engl J Med 1998; 339: 229-234
64. Pyörälä K, Pedersen TR, Kjeksus J, Faergeman O, Olsson AG, Thorgeirsson G. Cholesterol lowering with simvastatin improves prognosis of diabetic patients with coronary heart disease: a subgroup analysis of the Scandinavian Simvastatin Survival Study (4S). Diabetes Care 1997; 20: 614-620
65. Goldberg RB, Mellies MJ, Sacks FM et al. Cardiovascular events and their reduction with Pravastatin in diabetic and glucose-intolerant myocardial infarction survivors with average cholesterol levels: sub-group analyses in the Cholesterol And Recurrent Events (CARE) trial. Circulation 1998; 98: 2513-2519
66. Sacks FM, Pfeffer MA, Moyé LA et al. The effect of Pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels: Cholesterol And Recurrent Events Trial Investigators. N Engl J Med 1996; 335: 1001-1009
67. Sacks FM, Tonkin AM, Craven T et al. Coronary heart disease in patients with low LDL-cholesterol. Benefit of Pravastatin in diabetics and enhanced role for HDL-cholesterol and triglyerides as risk factors. Circulation 2002; 105: 1424-1428
68. Foody JM, Ferdinand FD, Pearce GL, Lytle BW, Cosgrove DM, Sprecher DL. HDL cholesterol level predicts survival in men after coronary artery bypass graft surgery: 20-year experience From The Cleveland Clinic Foundation. Circulation 2000; 102: 90III-94III
69. Campeau L, Hunninghake DB, Knatterud GL et al. Aggressive cholesterol lowering delays saphenous vein graft atherosclerosis in women, the elderly, and patients with associated risk factors: NHLBI Post Coronary Artery Bypass Graft Clinical Trial. Circulation 1999; 99: 3241-3247
70. American Diabetes Association. Position statement: management of dyslipidemia in adults with diabetes. Diabetes Care 2001; 23: 558-561
71. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol. Executive summary of the third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001; 285: 2486-2497
72. Tschoepe D, Roesen P. Heart disease in diabetes mellitus: a challenge for early diagnosis and intervention. Exp Clin Endocrinol Diabetes 1998; 106: 16-24
73. Kalter R, Saul C, Weinstein J. Cardiopulmonary bypass. Associated hemostatic abnormalities. J Thorac Cardiovasc Surg 1979; 77: 428
74. Zilla P, Fasol R, Groscurth et al. Blood platelets in cardiopulmonary bypass operations. J Thorac: Cardiovasc Surg 1989; 97: 379-388
75. Mangos GJ, Brown MA, Chan WY, Horton D, Trew P, Withwoth JA. Acute renal failure following cardiac surgery: incidences, outcomes and risk factors. Aust N Z J Med 1995; 25: 284-289
76. Suen WS, Mok CK, Chiu SW et al. Risk factors for angiology development of acute renal failure (ARF) requiring dialysis in patients undergoing cardiac surgery. Angiology 1998; 49: 789-800
77. Ostermann ME, Taube D, Morgan CJ, Evans TW. Acute renal failure following cardiopulmonary bypass: a changing picture. Intensive Care Med 2000; 26: 565-571
78. Brezis M, Rosen S, Epstein FH. The pathophysiological implications of medullary hypoxia. Am J Kidney Dis 1989; 13: 253-258
79. Bryan AG, Bolsin SN, Viana PT, Haloush H. Modification of the diuretic and natriuretic effect of a dopamine infusion by fluid loading in preoperative cardiac surgical patients. J Cardiothorac Vasc Anes 1995; 9: 158-163
80. Baudouin SV, Wiggins J, Keogh BF, Morgan CJ, Evans TW. Continuous veno-venous haemofiltration following cardio-pulmonary bypass. Intensive Care Med 1993; 19: 290-293
81. Bellomo R, Ronco C. Continuous hemofiltration in acute renal failure. Curr Op Anaest 1996; 9: 166-170
82. Pozzessere G, Valle E, De Crignis S et al. Abnormalities of cognitive function in IDDM revealed by P300 event-related potential analysis. Diabetes 1991; 40: 952-958
83. Kramer L, Fasching P, Madl C et al. Previous episodes of hypoglycemic coma are not associated with permanent cognitive brain dysfunction in IDDM patients on intensive insulin treatment. Diabetes 1998; 47: 1909-1914
84. Mochizuki Y, Oishi M, Hayakawa Yet al. Improvement of P300 latency by treatment in non-insulin-dependent diabetes mellitus. Clin Electroencephalogr 1998; 29: 194-196
85. Lynn GM, Stefanko K, Reed JF III, Gee W, Nicholas G. Risk factors for stroke after coronary artery bypass. J Thorac Cardiovasc Surg 1992; 104: 1518-1523
86. Newman MF, Wolman R, Kanchuger M et al. Multicenter preoperative stroke risk index for patients undergoing coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Circulation 1996; 94: 1174-80
87. Roach GW, Kanchuger M, Mangano CM et al. Adverse cerebral outcomes after coronary bypass surgery. N Engl J Med 1996; 335: 1: 857-1863
88. Smith P, Treasure T, Newman S, Joseph P, Ell P, Schneidau A, Harrison M. Cerebral consequences of cardiopulmonary bypass. Lancet 1986; 1: 823-825
89. Jorgenson HS, Reith J, Nakayama H et al. Copenhagen Stroke Study. Potentially reversible factors during the very acute phase of stroke and their impact on the prognosis: is there a large therapeutic potential to be explored? Cerebrovasc Dis 2001; 11: 207-211
90. Weir CJ, Murray GD, Dyker AG, Lees KR. Is hyperglycaemia an independent predictor of poor outcome after acute stroke? Results of a long-term follow up study. BMJ 1997; 314: 1303-1306