Is hyperglycaemia an independent predictor of poor outcome after acute stroke? Results of a long term follow up study

BMJ

Volumn 314, Issue 7090, 1997, Pages 1303-

  Weir, Christopher J ^a   Murray, Gordon D ^b   Dyker, Alexander G ^a   Lees, Kennedy R ^a  

^a WESTERN INFIRMARY   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ARTICLE; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; HYPERGLYCEMIA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; STROKE; SURVIVAL TIME;

EID: 0030966075     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.314.7090.1303     Document Type: Article

References (26)

1. O'Neill PA, Davies I, Fullerton KJ, Bennett D. Stress hormone and blood glucose response following acute stroke in the elderly. Stroke 1991; 22: 842–847.
2. Murros K, Fogelholm R, Kettunen S, Vuorela AL, Valve J. Blood glucose, glycosylated hemoglobin, and outcome of ischemic brain infarction. J Neurol Sci 1992; 111: 59–64.
3. Murros K, Fogelholm R, Kettunen S, Vuorela AL. Serum cortisol and outcome in ischemic brain infarction. J Neurol Sci 1993; 116: 12–17.
4. Woo J, Lam CWK, Kay R, Wong AHY, Teoh R, Nicholls MG. The influence of hyperglycemia and diabetes mellitus on immediate and 3-month morbidity and mortality after acute stroke. Arch Neurol 1990; 47: 1174–1177.
5. Woo E, Chan YW, Yu YL, Huan CY. Admission glucose level in relation to mortality and morbidity outcome in 252 stroke patients. Stroke 1988; 19: 185–91.
6. Candelise L, Landi G, Orazio EN, Boccardi E. Prognostic significance of hyperglycemia in acute stroke. Arch Neurol 1985; 42: 661–663.
7. Melamed E. Reactive hyperglycemia in patients with acute stroke. J Neurol Sci 1976; 29: 267–75.
8. Toni D, Sacchetti ML, Argentino C, Gentile M, Cavalletti C, Frontoni M, et al. Does hyperglycemia play a role on the outcome of acute ischemic stroke patients J Neurol 1992; 239: 382–386.
9. Jorgensen HS, Nakayama H, Raaschou HO, Olsen TS. Stroke in patients with diabetes: the Copenhagen stroke study. Stroke 1994; 25: 1977–84.
10. van Kooten F, Hoogerbrugge N, Naarding P, Koudstaal PJ. Hyperglycemia in the acute phase of stroke is not caused by stress. Stroke 1993; 24: 1129–32.
11. Kiers L, Davis SM, Larkins R, Hopper J, Tress B, Rossiter SC, et al. Stroke topography and outcome in relation to hyperglycaemia and diabetes. J Neurol Neurosurg Psychiatry 1992; 55: 263–70.
12. Bamford JM, Sandercock PAG, Dennis MS, Burn J, Warlow CP. Classification and natural-history of clinically identifiable subtypes of cerebral infarction. Lancet 1991; 337: 1521–1526.
13. Kendrick S, Clarke J. The Scottish record linkage system. Health Bull (Edinb) 1993; 51: 1–15.
14. Isles CG, Walker LM, Beevers GD, Brown I, Cameron HL, Clarke J, et al. Mortality in patients of the Glasgow blood pressure clinic. J Hypertens 1986; 4: 141–56.
15. West of Scotland Coronary Prevention Study Group. Computerised record linkage: compared with traditional patient follow-up methods in clinical trials and illustrated in a prospective epidemiological study. J Clin Epidemiol 1995; 48: 1441–52.
16. Cox DR. Regression models and life tables. J R Stat Soc B 1972; 34: 187–220.
17. Engelman L. Stepwise logistic regression. In: Dixon WJ, Brown MB, Engelman L, Jennrich RI, eds. BMDP statistical software manual. Berkeley: University of California Press, 1990: 1013–46.
18. Carlberg B, Asplund K, Hagg E. Course of blood pressure in different subsets of patients after acute stroke. Cerebrovasc Dis 1991; 1: 281–287.
19. Carlberg B, Asplund K, Hagg E. Factors influencing admission blood pressure levels in patients with acute stroke. Stroke 1991; 22: 527–30.
20. Helgason CM. Blood glucose and stroke. Stroke 1988; 19: 1049–53.
21. De Chiara S, Mancini M, Vaccaro O, Riccardi G, Ferrara LA, Gallotta G, et al. Cerebrovascular reactivity by transcranial Doppler ultrasonography in insulin-dependent diabetic patients. Cerebrovasc Dis 1993; 3: 111–115.
22. Rehncrona S, Rosen I, Siesjo BK. Brain lactic acidosis and ischemic damage. I: Biochemistry and neurophysiology. J Cereb Blood Flow Metab 1981; 1: 297–311.
23. Chew W, Kucharczyk J, Moseley M, Derugin N, Norman D. Hyperglycemia augments ischemic brain injury: in vivo MR imaging/spectroscopic study with nicardipine in cats with occluded middle cerebral arteries. Am J Neuroradiol 1991; 12: 603–609.
24. Pulsinelli WA, Waldman S, Rawlinson D, Plum F. Moderate hyperglycemia augments ischemic brain damage: a neuropathologic study in the rat. Neurology 1982; 32: 1239–46.
25. National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333: 1581–1587.
26. Mohr JP, Orgogozo JM, Harrison MJG, Hennerici M, Wahlgren NG, Gelmers JH, et al. Meta-analysis of oral nimodipine trials in acute ischaemic stroke. Cerebrovasc Dis 1994; 4: 197–203.