The association of reduced endothelium derived relaxing factor-no production with endothelial damage and increased in vivo platelet activation in patients with diabetes mellitus

Thrombosis Research

Volumn 86, Issue 2, 1997, Pages 173-180

  Huszka, Marianna ^a   Kaplar, Miklos ^a   Rejto, Laszlo ^a   Tornai, Istvan ^a   Palatka, Karoly ^a   Laszlo, Pal ^a   Udvardy, Miklos ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Beta thromboglobulin; Diabetic angiopathy; EDRF NO; Lipid peroxidation; Soluble thrombomodulin; Von Willebrand factor

Indexed keywords

ENDOTHELIUM DERIVED RELAXING FACTOR; THROMBOMODULIN; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DIABETIC ANGIOPATHY; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION;

ADULT; BLOOD GLUCOSE; DIABETES COMPLICATIONS; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; LIPID PEROXIDATION; MALE; MIDDLE AGED; NITRATES; NITRIC OXIDE; NITRITES; PLATELET ACTIVATION;

EID: 0030911304     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(97)00060-1     Document Type: Article

References (21)

1. COLWELL, J.A., WINOCOUR, E.D., LOPEZ-VIRELLA, E.: New concepts about the pathogenesis of atherosclerosis in diabetes mellitus. Scand J Haematol 27,65-91, 1990
2. GLASSER, S.P., SELWYN, A.P., GANZ, P.: Atherosclerosis: risk factors and the vascular endothelium. Am Heart J 131,379-84, 1996
3. UDVARDY M., TOROK I., RAK K.: Plasma thromboxane and prostacyclin metabolite ratio in atherosclerosis and diabetes mellitus. Thromb Res 47,479-84, 1987
4. ANGGARD, E.E.: Nitric oxide: mediator, murderer and medicine. Lancet 343,1199-1206, 1994
5. FURCHGOTT, R.F.: Introduction to EDRF-NO research. J Cardiovasc Pharmacol 22, Suppl. 7,1-2, 1993
6. DELONCA, J., BALTEUX, V., GIRAUD, T., SANCHEZ, R.Y.: EDRF/NO and endothelial functions. Arch Mal Coeur Vaiss 86,1617-1624, 1993
7. ANGGARD, E.E.: Endogeneous and exogeneous nitrates. Acta Anaesthesiol Scand Suppl. 97P,7-10, 1992
8. SIKORSKI, B.W., HODGSON, W.C., KING, R.: Effects of haemoglobin and N-nitro-L-arginine on constrictor and dilator responses of aortic rings from streptozotocin diabetic rats. Eur J Pharmacol 242,275-282, 1995
9. STEVENS, M.J., DANANBERG, J., FELDMAN, E.L., LATTIMER, S.A., KAMIJO, M., THOMAS, T.P., SHINDO, H., SIMA, A.A., GREENE, D:A.: The linked roles of nitric oxide, aldose reductase and Na-K ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat. J Clin Invest 94,853-859, 1994
10. BANK, N., AYNEDJIAN, H.S.: Role of EDRF in diabetic renal hyperfiltration. Kidney Int 43,1306-12, 1993
11. YAMADA, K., NAKANO, H., NAKAYAMA, M., MIURA, Y., NISHIMURA M., TSUCHIDA, H., MIMURA, N.: Endothelium dependent relaxation in peripheral vasculature and kidney of non insulin dependent diabetes mellitus. J Diabetes Compl 9,203-7, 1995
12. JOHNSTONE, M.J., CREAGER, S.J., SCALES, K.M., CUSCO, J.A., LEE B.K., CREAGER, M.A.: Impaired endothelium dependent vasodilation in patients with insulin dependent diabetes mellitus. Circulation 88,2510-6, 1993
13. ELLIOTT, T.G., COCKCROFT, J.R., GROOP, P.H., VIBERTI, G.C., RITTER, J.M.: Inhibition of nitric oxide synthesis in the forearm vasculature of insulin dependent diabetic patients: blunted vasoconstriction in patients with microalbuminuria. Clin Sci 55,687-93, 1993
14. LOSKOVE, J.A., FRISHMAN, W.H.: Nitric oxide donors in the treatment of cardiovascular and pulmonary diseases. Amer Heart J 129,604-13, 1995
15. SUNDARAM, R.K., BHASKAR, A., VIJAYALINGAM, S., VISWANATHAN, M., MOHAN, R., SHANMUGASUNDARAM, K.R,: Antioxidant status and lipid peroxidation in type II diabetes mellitus with and without complications. Clin Sci 90,255-60, 1996
16. PIEPER, G.M., PELTIER, B.A.: Amelioration by L-arginine of a dysfunctional arginine/nitric oxide pathway in diabetic endothelium. J Cardiovasc Pharmacol 25,397-403, 1995
17. VERDON, C.P. BURTON, J.A., PRIOR, R.L.: Sample pretreatment with nitrate reductase and glucose-6-phosphate dehydrogenase quantitatively reduces nitrate while avoiding interference by NADP+ when the Griess reaction is used to assay for nitrite. Anal Biochem 224,502-508, 1995
18. ANDO, Y., YAMASHITA, T., TANAKA, Y., TASHIMA, K., YONEHARA, T., GOTOH, T., SAKASHITA, N., UCHIDO, M., ANDO, M.: Role of nitric oxide in the peripheral vessels of patients familial amyloidotic polyneuropathy type I. J Auton Nerv Syst 50,79-85, 1994
19. WENNALM, A., BENTHIN, G., EDLUND, A., JUNGERSTEN, L., KIELER-JENSEN, N., LUNDIN, S., WESTFELT, U.N., PETERSSON, A.S., WAAGSTEIN, F.: Metabolism and excretion of nitric oxide in humans. An experimental and clinical study. Circ Res 73, 1121-1127, 1993
20. KANNO, K., HIRATA, Y., EMORI, T., OHTA, K., EGUCHI, S., MAI, T., MARUMO, F.: L-arginine infusion induces hypotension and diuresis/natriuresis with concomitant increased urinary excretion of nitrite/nitrate and cyclic GMP in humans. Clin Exp Pharmacol Physiol 79,619-625, 1992
21. MILLER, N.J., RICE-EVANS, C., DAVIE, M.J., GOPINATHAN, V., MILNER, A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clinical Science 84,407-412, 1993