The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells

British Journal of Pharmacology

Volumn 143, Issue 7, 2004, Pages 890-898

  Mühl, Heiko ^a   Paulukat, Jens ^a   Höfler, Sonja ^a   Hellmuth, Markus ^a   Franzen, Rochus ^a   Pfeilschifter, Josef ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Apoptosis; Butyrate; Colon carcinoma cells; Heme oxygenase 1; Ritonavir

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BUTYRIC ACID; CASPASE 3; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA INHIBITOR; MESSENGER RNA; PROTEIN C FOS; PROTEIN C JUN; PROTEINASE INHIBITOR; RITONAVIR; SHORT CHAIN FATTY ACID; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL GROWTH; COLITIS; COLON CARCINOGENESIS; COLON CARCINOMA; CONTROLLED STUDY; DRUG POTENCY; DRUG POTENTIATION; ELECTROPHORETIC MOBILITY; ENZYME ANALYSIS; ENZYME INDUCTION; GROWTH INHIBITION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNOMODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEINASE INHIBITION; REGULATORY MECHANISM; TRANSCRIPTION REGULATION;

APOPTOSIS; BUTYRATES; CASPASE 3; CASPASES; CELL LINE, TUMOR; COLONIC NEOPLASMS; DNA; DNA FRAGMENTATION; DRUG SYNERGISM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HEME OXYGENASE (DECYCLIZING); HEME OXYGENASE-1; HIV PROTEASE INHIBITORS; HUMANS; IMMUNOBLOTTING; MEMBRANE PROTEINS; NUCLEASE PROTECTION ASSAYS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RITONAVIR; RNA, MESSENGER;

EID: 10844266510     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706023     Document Type: Article

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