Induction of heme oxygenase-1 and dilatation of hepatic sinusoids by an administration of pyrrolidine dithiocarbamate in rat livers

Journal of Surgical Research

Volumn 115, Issue 2, 2003, Pages 310-317

  Hata, Koichiro ^a   Yamamoto, Yuzo ^a   Nakajima, Akio ^a   Taura, Kojiro ^a   Yonezawa, Kei ^a   Uchinami, Hiroshi ^a   Ikeda, Fusao ^a   Yamaoka, Yoshio ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Heme oxygenase 1; Hepatic microcirculation; Intravital microscopy; Pyrrolidine dithiocarbamate; Sinusoidal dilatation

Indexed keywords

HEME OXYGENASE 1; HEME OXYGENASE INHIBITOR; MESSENGER RNA; PROTOPORPHYRIN ZINC; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INDUCTION; ENZYME LOCALIZATION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; KUPFFER CELL; LIVER CELL; LIVER CIRCULATION; LIVER SINUSOID; LIVER SIZE; MALE; MICROCIRCULATION; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0345802681     PISSN: 00224804     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jss.2003.08.240     Document Type: Article

References (23)

1. Saad S., Kanai M., Awane M., Yamamoto Y., Morimoto T., Isselhard W., Minor T., Troidl H., Ozawa K., Yamaoka Y. Protective effect of heat shock pretreatment with heat shock protein induction before hepatic warm ischemic injury caused by Pringle's maneuver. Surgery. 118:1995;510.
2. Yamamoto Y., Kume M., Yamaoka Y. Implications of heat shock proteins during liver surgery and liver perfusion. Recent Results Cancer Res. 147:1998;157.
3. Hawaleshka A., Jacobsohn E. Ischaemic preconditioning Mechanisms and potential clinical applications. Can. J. Anaesth. 45:1998;670.
4. Peralta C., Bulbena O., Xaus C., Prats N., Cutrin J.C., Poli G., Gelpi E., Rosello-Catafau J. Ischemic preconditioning A defense mechanism against the reactive oxygen species generated after hepatic ischemia reperfusion. Transplantation. 73:2002;1203.
5. Kume M., Yamamoto Y., Yamagami K., Ishikawa Y., Uchinami H., Yamaoka Y. Pharmacological hepatic preconditioning Involvement of 70-kDa heat shock proteins (HSP72 and HSP73) in ischaemic tolerance after intravenous administration of doxorubicin. Br. J. Surg. 87:2000;1168.
6. Ito K., Ozasa H., Sanada K., Horikawa S. Doxorubicin preconditioning A protection against rat hepatic ischemia-reperfusion injury. Hepatology. 31:2000;416.
7. Terajima H., Enders G., Thiaener A., Hammer C., Kondo T., Thiery J., Yamamoto Y., Yamaoka Y., Messmer K. Impact of hyperthermic preconditioning on postischemic hepatic microcirculatory disturbances in an isolated perfusion model of the rat liver. Hepatology. 31:2000;407.
8. Redaelli C.A., Tian Y.H., Schaffner T., Ledermann M., Baer H.U., Dufour J.F. Extended preservation of rat liver graft by induction of heme oxygenase-1. Hepatology. 35:2002;1082.
9. Suematsu M., Ishimura Y. The heme oxygenase-carbon monoxide system A regulator of hepatobiliary function. Hepatology. 31:2000;3.
10. Stuhlmeier K.M. Activation and regulation of Hsp32 and Hsp70. Eur. J. Biochem. 267:2000;1161.
11. Hellmuth M., Wetzler C., Nold M., Chang J.H., Frank S., Pfeilschifter J., Muhl H. Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate. Carcinogenesis. 23:2002;1273.
12. Yonezawa K., Yamamoto Y., Yamamoto H., Ishikawa Y., Uchinami H., Taura K., Nakajima A., Yamaoka Y. Suppression of tumor necrosis factor-alpha production and neutrophil infiltration during ischemia-reperfusion injury of the liver after heat shock preconditioning. J. Hepatol. 35:2001;619.
13. Goda N., Suzuki K., Naito M., Takeoka S., Tsuchida E., Ishimura Y., Tamatani T., Suematsu M. Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation. J. Clin. Invest. 101:1998;604.
14. Suematsu M., Goda N., Sano T., Kashiwagi S., Egawa T., Shinoda Y., Ishimura Y. Carbon monoxide An endogenous modulator of sinusoidal tone in the perfused rat liver . J. Clin. Invest. 96:1995;2431.
15. Wakabayashi Y., Takamiya R., Mizuki A., Kyokane T., Goda N., Yamaguchi T., Takeoka S., Tsuchida E., Suematsu M., Ishimura Y. Carbon monoxide overproduced by heme oxygenase-1 causes a reduction of vascular resistance in perfused rat liver. Am. J. Physiol. 277:1999;G1088.
16. Rensing H., Bauer I., Zhang J.X., Paxian M., Pannen B.H., Yokoyama Y., Clemens M.G., Bauer M. Endothelin-1 and heme oxygenase-1 as modulators of sinusoidal tone in the stress-exposed rat liver. Hepatology. 36:2002;1453.
17. Serracino-Inglott F., Habib N.A., Mathie R.T. Hepatic ischemia-reperfusion injury. Am. J. Surg. 181:2001;160.
18. Pannen B.H., Bauer M. Differential regulation of hepatic arterial and portal venous vascular resistance by nitric oxide and carbon monoxide in rats. Life Sci. 62:1998;2025.
19. Maines M.D. Heme oxygenase Function, multiplicity, regulatory mechanisms, and clinical applications . FASEB J. 2:1988;2557.
20. Kim S.H., Han S.I., Oh S.Y., Chung H.Y., Kim H.D., Kang H.S. Activation of heat shock factor 1 by pyrrolidine dithiocarbamate is mediated by its activities as pro-oxidant and thiol modulator. Biochem. Biophys. Res. Commun. 281:2001;367.
21. Hartsfield C.L., Alam J., Choi A.M. Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate. FASEB J. 12:1998;1675.
22. Bauer I., Wanner G.A., Rensing H., Alte C., Miescher E.A., Wolf B., Pannen B.H., Clemens M.G., Bauer M. Expression pattern of heme oxygenase isoenzymes 1 and 2 in normal and stress-exposed rat liver. Hepatology. 27:1998;829.
23. Baranano D.E., Rao M., Ferris C.D., Snyder S.H. From the cover Biliverdin reductase: A major physiologic cytoprotectant. Proc. Natl. Acad. Sci. USA. 99:2002;16093.