Highly stereoselective Grignard addition to cis-substituted C-cyclopropylaldonitrones. The bisected s-trans transition state can be stabilized effectively by the Lewis acid-coordination

Journal of Organic Chemistry

Volumn 69, Issue 26, 2004, Pages 9143-9150

  Kazuta, Yuji ^a   Abe, Hiroshi ^a   Matsuda, Akira ^a   Shuto, Satoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITION REACTIONS; CHELATION; CHEMICAL BONDS; CONFORMATIONS; ELECTRONS; STEREOCHEMISTRY; SUBSTITUTION REACTIONS;

CONFORMATION-CONTROLLED PATHWAYS; GRIGNARD ADDITION; HYPERCONJUGATION; STEREOSELECTIVITY;

KETONES;

BENZYL DERIVATIVE; BIPHENYL DERIVATIVE; CYCLOPROPANE DERIVATIVE; LEWIS ACID; MAGNESIUM DERIVATIVE; NITRONE DERIVATIVE; SILANE DERIVATIVE;

ARTICLE; CHELATION; CHEMICAL BOND; CIS TRANS ISOMERISM; CONFORMATION; CONJUGATION; GRIGNARD REACTION; MOLECULAR STABILITY; REACTION ANALYSIS; STEREOCHEMISTRY; STEREOSPECIFICITY;

EID: 10844252307     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048637e     Document Type: Article

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