Synthesis of cinnamic acids and related isosteres as potent and selective αvβ3 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1471-1476

  Penning, Thomas D ^a,b   Russell, Mark A ^a   Chen, Barbara B ^a   Chen, Helen Y ^a   Desai, Bipin N ^a   Docter, Stephen H ^a   Edwards, David J ^a   Gesicki, Glen J ^a   Liang, Chi Dean ^a   Malecha, James W ^a   Yu, Stella S ^a   Engleman, V Wayne ^a   Freeman, Sandra K ^a   Hanneke, Melanie L ^a   Shannon, Kristen E ^a   Westlin, Marisa M ^a   Nickols, G Allen ^a  

^a PFIZER INC   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 3 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA3 INTEGRIN; CARBOXYLIC ACID DERIVATIVE; CINNAMIC ACID; HYDROCINNAMIC ACID DERIVATIVE; PHENOXYACETIC ACID DERIVATIVE; PHENYLALANINE; VITRONECTIN RECEPTOR;

ARTICLE; DRUG SELECTIVITY; DRUG SYNTHESIS; MITSUNOBU REACTION;

CINNAMATES; HUMANS; INTEGRIN ALPHAVBETA3; STEREOISOMERISM;

EID: 10744229258     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.01.015     Document Type: Article

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