A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits

Free Radical Biology and Medicine

Volumn 35, Issue 1, 2003, Pages 102-113

  Pi, Jingbo ^a,b,f   Horiguchi, Satomi ^a   Sun, Yang ^a   Nikaido, Masatoshi ^a   Shimojo, Nobuhiro ^a   Hayashi, Toshio ^c   Yamauchi, Hiroshi ^d   Itoh, Ken ^a   Yamamoto, Masayuki ^a   Sun, Guifan ^b   Waalkes, Michael P ^e   Kumagai, Yoshito ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b CHINA MEDICAL UNIVERSITY   (China)

^c NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^f Lab of Molecular Carcinogenesis   (United States)

Author keywords

Arsenate; Free radicals; Nitric oxide; Oral exposure; Rabbit; Superoxide; Tetrahydrobiopterin; Vasoconstriction

Indexed keywords

ACETYLCHOLINE; ALLOPURINOL; ARSENIC ACID; CALCIMYCIN; CALCIUM IONOPHORE; CYCLIC GMP; DIPHENYLIODONIUM SALT; DRINKING WATER; HYDROGEN PEROXIDE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; PTERIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE; TETRAHYDROBIOPTERIN; XANTHINE OXIDASE INHIBITOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTERY CONSTRICTION; ARTERY TONE; ARTICLE; BIOAVAILABILITY; BLOOD LEVEL; CONTROLLED STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; URINE LEVEL;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 10744228609     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(03)00269-7     Document Type: Article

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