Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme

Structure

Volumn 11, Issue 6, 2003, Pages 627-636

  Underwood, Kathryn W ^a   Parris, Kevin D ^a   Federico, Elizabeth ^a   Mosyak, Lidia ^a   Czerwinski, Robert M ^a   Shane, Tania ^a   Taylor, Meggin ^a   Svenson, Kristine ^a   Liu, Yan ^a   Hsiao, Chu Lai ^a   Wolfrom, Scott ^a   Maguire, Michelle ^a   Malakian, Karl ^a   Telliez, Jean Baptiste ^a   Lin, Lih Ling ^a   Kriz, Ronald W ^a   Seehra, Jasbir ^a   Somers, William S ^a   Stahl, Mark L ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE 1; PEPTIDE; PROTEIN SERINE KINASE; SERINE; STAUROSPORINE; THREONINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; GENE DELETION; KINETICS; MICHAELIS CONSTANT; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

EID: 10744225800     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(03)00092-3     Document Type: Article

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