-
1
-
-
0031754373
-
Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor-1 activity
-
Agani F and Semenza GL. 1998. Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor-1 activity. Mol Pharmacol 54:749-754.
-
(1998)
Mol Pharmacol
, vol.54
, pp. 749-754
-
-
Agani, F.1
Semenza, G.L.2
-
2
-
-
0029585109
-
The anoxic fibroblast response is an early-stage wound healing program
-
Anderson GR, Volpe CM, Russo CA, Stoler DL, Miloro SM. 1995. The anoxic fibroblast response is an early-stage wound healing program. J Surg Res 59:666-674.
-
(1995)
J Surg Res
, vol.59
, pp. 666-674
-
-
Anderson, G.R.1
Volpe, C.M.2
Russo, C.A.3
Stoler, D.L.4
Miloro, S.M.5
-
3
-
-
0033981473
-
The plasminogen activation system in tumor growth, invasion, and metastasis
-
Andreasen PA, Egelund R, Petersen HH. 2000. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 57:25-40.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 25-40
-
-
Andreasen, P.A.1
Egelund, R.2
Petersen, H.H.3
-
5
-
-
0035866784
-
Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation
-
Chen EY, Mazure NM, Cooper JA, Giacia AJ. 2001. Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer Res 61:2429-2433.
-
(2001)
Cancer Res
, vol.61
, pp. 2429-2433
-
-
Chen, E.Y.1
Mazure, N.M.2
Cooper, J.A.3
Giacia, A.J.4
-
6
-
-
0033664260
-
Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblast
-
Chin GS, Liu W, Steinbrech D, Hsu M, Levinson H, Longaker MT. 2000. Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblast. Plast Reconstr Surg 106:1532-1540.
-
(2000)
Plast Reconstr Surg
, vol.106
, pp. 1532-1540
-
-
Chin, G.S.1
Liu, W.2
Steinbrech, D.3
Hsu, M.4
Levinson, H.5
Longaker, M.T.6
-
8
-
-
0031057091
-
Hypoxia regulates the expression of vascular permiability factor/ vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin
-
Detmar M, Brown LF, Berse B, Jackman RW, Elicker BM, Dvorak. 1997. Hypoxia regulates the expression of vascular permiability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. J Invest Dermatol 108:263-268.
-
(1997)
J Invest Dermatol
, vol.108
, pp. 263-268
-
-
Detmar, M.1
Brown, L.F.2
Berse, B.3
Jackman, R.W.4
Elicker, B.M.5
Dvorak6
-
9
-
-
0038757584
-
Akt activation by reactive oxygen species is independent from tyrosine kinase receptor phosphorylation and requires Src activity
-
Esposito F, Chirico G, Gesualdi NM, Posadas I, Ammendola R, Russo T, Cirino G and Cimino F. 2003. Akt activation by reactive oxygen species is independent from tyrosine kinase receptor phosphorylation and requires Src activity. J Biol Chem 278:20828-20834.
-
(2003)
J Biol Chem
, vol.278
, pp. 20828-20834
-
-
Esposito, F.1
Chirico, G.2
Gesualdi, N.M.3
Posadas, I.4
Ammendola, R.5
Russo, T.6
Cirino, G.7
Cimino, F.8
-
10
-
-
0035087539
-
Quantitative gene expression profiles of human liver-derived cell lines exposed to moderate hypoxia
-
Fink T, Ebbesen P, Zachar V. 2001. Quantitative gene expression profiles of human liver-derived cell lines exposed to moderate hypoxia. Cell Physiol Biochem. 11:105-114.
-
(2001)
Cell Physiol Biochem
, vol.11
, pp. 105-114
-
-
Fink, T.1
Ebbesen, P.2
Zachar, V.3
-
11
-
-
0037085780
-
Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1
-
Fink T, Kazlauskas A, Poellinger L, Ebbesen P, Zachar V. 2002. Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1. Blood 99:2077-2083.
-
(2002)
Blood
, vol.99
, pp. 2077-2083
-
-
Fink, T.1
Kazlauskas, A.2
Poellinger, L.3
Ebbesen, P.4
Zachar, V.5
-
12
-
-
0031797364
-
Stimulation of plasminogen activator inhobitor-1 expression in immortalized human trophoblast cells cultured under low levels of oxygen
-
Fitzpatrick TE, Graham CH. 1998. Stimulation of plasminogen activator inhobitor-1 expression in immortalized human trophoblast cells cultured under low levels of oxygen. Exp Cell Res 245:155-162.
-
(1998)
Exp Cell Res
, vol.245
, pp. 155-162
-
-
Fitzpatrick, T.E.1
Graham, C.H.2
-
13
-
-
0037224827
-
Genistein activates p38 Map kinases, inactivates ERK1/2 and decreases Cdc25C expression in immortalized human mammary epithelial cells
-
Frey RS, Singletary KW. 2003. Genistein activates p38 Map kinases, inactivates ERK1/2 and decreases Cdc25C expression in immortalized human mammary epithelial cells. J Nutr 133:226-231.
-
(2003)
J Nutr
, vol.133
, pp. 226-231
-
-
Frey, R.S.1
Singletary, K.W.2
-
14
-
-
0033134112
-
Differential regulation of PAI-1 gene expression in human fibroblasts predisposed to a fibric phenotype
-
Higgins PJ, Slack JK, Diegelmann RF, Staiano-Coico L. 1999. Differential regulation of PAI-1 gene expression in human fibroblasts predisposed to a fibric phenotype. Exp Cell Res 248:634-642.
-
(1999)
Exp Cell Res
, vol.248
, pp. 634-642
-
-
Higgins, P.J.1
Slack, J.K.2
Diegelmann, R.F.3
Staiano-Coico, L.4
-
15
-
-
0033213996
-
The plasminogen activator system: Biology and regulation
-
Irigoyen JP, Mun̂oz-Cánoves P, Montero J, Koziczak M, Nagamine Y. 1999. The plasminogen activator system: Biology and regulation. Cell Mol Life Sci 56:104-132.
-
(1999)
Cell Mol Life Sci
, vol.56
, pp. 104-132
-
-
Irigoyen, J.P.1
Mun̂oz-Cánoves, P.2
Montero, J.3
Koziczak, M.4
Nagamine, Y.5
-
16
-
-
0035917313
-
2 sensing
-
2 sensing. Science 292:464-468.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr., W.G.10
-
17
-
-
0034925041
-
Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1
-
Jiang BH, Jiang GQ, Zheng JZ, Lu ZM, Hunter T, Vogt PK. 2000. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1. Cell Growth Differ 12:363-369.
-
(2000)
Cell Growth Differ
, vol.12
, pp. 363-369
-
-
Jiang, B.H.1
Jiang, G.Q.2
Zheng, J.Z.3
Lu, Z.M.4
Hunter, T.5
Vogt, P.K.6
-
18
-
-
0037067454
-
Hypoxic induction of hypoxia inducible factor is mediated via the adaptor protein Sch in endothelial cells
-
Jung F, Haendeler J, Hoffmann J, Reissner A, Dernbach E, Zeiher AM, Dimmeler S. 2002. Hypoxic induction of hypoxia inducible factor is mediated via the adaptor protein Sch in endothelial cells. Cir Res 91:38-45.
-
(2002)
Cir Res
, vol.91
, pp. 38-45
-
-
Jung, F.1
Haendeler, J.2
Hoffmann, J.3
Reissner, A.4
Dernbach, E.5
Zeiher, A.M.6
Dimmeler, S.7
-
19
-
-
0032795850
-
Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes
-
Kietzmann T, Roth U, Jungermann K. 1999. Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes. Blood 94:4177-4185.
-
(1999)
Blood
, vol.94
, pp. 4177-4185
-
-
Kietzmann, T.1
Roth, U.2
Jungermann, K.3
-
20
-
-
0037391958
-
Regulation of the hypoxia-dependent Plasminogen activator inhibitor 1 expression by MAP kinases
-
Kietzmann T, Jungermann K, Görlach A. 2003. Regulation of the hypoxia-dependent Plasminogen activator inhibitor 1 expression by MAP kinases. Thromb Haemost 89:666-673.
-
(2003)
Thromb Haemost
, vol.89
, pp. 666-673
-
-
Kietzmann, T.1
Jungermann, K.2
Görlach, A.3
-
21
-
-
0026843757
-
The microvessels in hypertrophic scars, keloids and related lesions: A review
-
Kischer CW. 1992. The microvessels in hypertrophic scars, keloids and related lesions: A review. J Submicrosc Cytol Pathol 24:281-296.
-
(1992)
J Submicrosc Cytol Pathol
, vol.24
, pp. 281-296
-
-
Kischer, C.W.1
-
22
-
-
0019939174
-
Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids
-
Kischer CW, Thies AC, Chvapil M. 1982. Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids. Human Pathol 13:819-824.
-
(1982)
Human Pathol
, vol.13
, pp. 819-824
-
-
Kischer, C.W.1
Thies, A.C.2
Chvapil, M.3
-
23
-
-
0034652779
-
Candidate genes for hypoxic tumor phenotype
-
Koong AC, Denko NC, Hudson KM, Schindler C, Swiersz L, Koch C, Evans S, Ibrahim H, Le QT, Terris DJ, Giaccia AJ. 2000. Candidate genes for hypoxic tumor phenotype. Cancer Res 60:883-887.
-
(2000)
Cancer Res
, vol.60
, pp. 883-887
-
-
Koong, A.C.1
Denko, N.C.2
Hudson, K.M.3
Schindler, C.4
Swiersz, L.5
Koch, C.6
Evans, S.7
Ibrahim, H.8
Le, Q.T.9
Terris, D.J.10
Giaccia, A.J.11
-
24
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinas/Akt signaling pathway in Ha-rastransformed cells through a hypoxia inducible factor-1 transcriptional element
-
Mazure N, Chen Y, Laderoute K, Giaccia A. 1997. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinas/Akt signaling pathway in Ha-rastransformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 90:3322-3331.
-
(1997)
Blood
, vol.90
, pp. 3322-3331
-
-
Mazure, N.1
Chen, Y.2
Laderoute, K.3
Giaccia, A.4
-
25
-
-
0032541029
-
p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
-
Milanini J, Viñals F, Pouysségur J, Pagès G. 1998. p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts. J Biol Chem 273:18165-18172.
-
(1998)
J Biol Chem
, vol.273
, pp. 18165-18172
-
-
Milanini, J.1
Viñals, F.2
Pouysségur, J.3
Pagès, G.4
-
26
-
-
0033981845
-
ERK activation upon hypoxia: Involvement in HIF-1 activation
-
Minet E, Arnould T, Michel G, Roland I, Mottet D, Raes M, Remacle J, Michieles C. 2000. ERK activation upon hypoxia: Involvement in HIF-1 activation. FEBS Lett 468:53-58.
-
(2000)
FEBS Lett
, vol.468
, pp. 53-58
-
-
Minet, E.1
Arnould, T.2
Michel, G.3
Roland, I.4
Mottet, D.5
Raes, M.6
Remacle, J.7
Michieles, C.8
-
27
-
-
0035478294
-
Transduction pathways involved in hypoxia-inducible factor phosphorylation and activation
-
Minet E, Michel G, Mottet D, Raes M and Michiels C. 2001. Transduction pathways involved in hypoxia-inducible factor phosphorylation and activation. Free Radic Biol Med 31:847-855.
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 847-855
-
-
Minet, E.1
Michel, G.2
Mottet, D.3
Raes, M.4
Michiels, C.5
-
28
-
-
0029068339
-
Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
-
Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. 1995. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 375:577-581.
-
(1995)
Nature
, vol.375
, pp. 577-581
-
-
Mukhopadhyay, D.1
Tsiokas, L.2
Zhou, X.M.3
Foster, D.4
Brugge, J.S.5
Sukhatme, V.P.6
-
30
-
-
0032167429
-
Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition
-
Pinsky DJ, Liao H, Lawson CA, Yan SF, Chen JX, Carmeliet P, Loskutoff DJ. 1998. Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition. J Clin Invest 102:919-928.
-
(1998)
J Clin Invest
, vol.102
, pp. 919-928
-
-
Pinsky, D.J.1
Liao, H.2
Lawson, C.A.3
Yan, S.F.4
Chen, J.X.5
Carmeliet, P.6
Loskutoff, D.J.7
-
31
-
-
0030989114
-
Protein tyrosine kinases activity is required for oxidant-induced extracellular signal-regulated protein kinase activation and c-fos/c-jun expression
-
Rao GN. 1997. Protein tyrosine kinases activity is required for oxidant-induced extracellular signal-regulated protein kinase activation and c-fos/c-jun expression. Cell Signal 9:181-187.
-
(1997)
Cell Signal
, vol.9
, pp. 181-187
-
-
Rao, G.N.1
-
32
-
-
0032725554
-
p42/44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor-1alpha and enhance the transcriptional activity of HIF-1
-
Richard DE, Berra E, Gothie, Roux D, Pouyssegur J. 1999. p42/44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor-1alpha and enhance the transcriptional activity of HIF-1. J Biol Chem 274:32631-32637.
-
(1999)
J Biol Chem
, vol.274
, pp. 32631-32637
-
-
Richard, D.E.1
Berra, E.2
Gothie3
Roux, D.4
Pouyssegur, J.5
-
33
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells
-
Richard DE, Berra E, and Pouyssegur J. 2000. Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells. J Biol Chem 275:26765-26771.
-
(2000)
J Biol Chem
, vol.275
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
34
-
-
0037227385
-
Modulation of the expression of tissue Plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts
-
Saed GM, Diamond MP. 2003. Modulation of the expression of tissue Plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts. Fert Steril 79:164-168.
-
(2003)
Fert Steril
, vol.79
, pp. 164-168
-
-
Saed, G.M.1
Diamond, M.P.2
-
35
-
-
0031038419
-
Complex role of protein phosphorylation in gene activation by hypoxia
-
Salceda S, Beck I, Srinivas V and Caro J. 1997. Complex role of protein phosphorylation in gene activation by hypoxia. Kidney Int 51:556-559.
-
(1997)
Kidney Int
, vol.51
, pp. 556-559
-
-
Salceda, S.1
Beck, I.2
Srinivas, V.3
Caro, J.4
-
36
-
-
0036710591
-
Signal transduction to hypoxia-inducible factor 1
-
Semenza GL. 2002. Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol 64:993-998.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 993-998
-
-
Semenza, G.L.1
-
37
-
-
0035860246
-
MAPK and Akt act cooperatively but independently on hypoxia inducible factor 1alpha in rasV12 upregulation of VEGF
-
Sodhi A, Montaner S, Miyazaki H, Gutkind JS. 2001. MAPK and Akt act cooperatively but independently on hypoxia inducible factor 1alpha in rasV12 upregulation of VEGF. Biochem Biophys Res Commun 287:292-300.
-
(2001)
Biochem Biophys Res Commun
, vol.287
, pp. 292-300
-
-
Sodhi, A.1
Montaner, S.2
Miyazaki, H.3
Gutkind, J.S.4
-
38
-
-
0033563711
-
Fibroblast response to hypoxia: The relationship between angiogenesis and matrix regulation
-
Steinberg DS, Longaker MT, Mehrara BJ, Saadeh PB, Chin GS, Gerrets RP, Chau DC, Rowe NM, Gittes GK. 1999. Fibroblast response to hypoxia: The relationship between angiogenesis and matrix regulation. J Surg Res 84:127-133.
-
(1999)
J Surg Res
, vol.84
, pp. 127-133
-
-
Steinberg, D.S.1
Longaker, M.T.2
Mehrara, B.J.3
Saadeh, P.B.4
Chin, G.S.5
Gerrets, R.P.6
Chau, D.C.7
Rowe, N.M.8
Gittes, G.K.9
-
39
-
-
0029916476
-
Increased PAI-1 may account for the altered fibrinolysis by keloid fibroblasts
-
Tuan TL, Zhu JY, Sun B, Nichter LS, Nimni ME, Laug WE. 1996. Increased PAI-1 may account for the altered fibrinolysis by keloid fibroblasts. J Invest Dermatol 106:1007-1011.
-
(1996)
J Invest Dermatol
, vol.106
, pp. 1007-1011
-
-
Tuan, T.L.1
Zhu, J.Y.2
Sun, B.3
Nichter, L.S.4
Nimni, M.E.5
Laug, W.E.6
-
40
-
-
0037408433
-
Increased plasminogen activator inhibitor-1 in keloid fibroblasts may account for their elevated collagen accumulation in fibrin gel cultures
-
Tuan TL, Wu HY, Hang EY, Chong SN, Laug W, Messadi D, Kelley P, and Le A. 2003. Increased plasminogen activator inhibitor-1 in keloid fibroblasts may account for their elevated collagen accumulation in fibrin gel cultures. Am J Patholol 162:1579-1589.
-
(2003)
Am J Patholol
, vol.162
, pp. 1579-1589
-
-
Tuan, T.L.1
Wu, H.Y.2
Hang, E.Y.3
Chong, S.N.4
Laug, W.5
Messadi, D.6
Kelley, P.7
Le, A.8
-
41
-
-
0034032489
-
Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through genistein-sensitive tyrosine kinase pathways in vascular endothelial cells
-
Uchiyama T, Kurabayashi M, Ohyama Y, Utsugi T, Akuzawa N, Sato M, Tomono S, Kawazu S, Nagai R. 2000. Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through genistein-sensitive tyrosine kinase pathways in vascular endothelial cells. Arterioscler Thromb Vasc Biol 20:1155-1161.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1155-1161
-
-
Uchiyama, T.1
Kurabayashi, M.2
Ohyama, Y.3
Utsugi, T.4
Akuzawa, N.5
Sato, M.6
Tomono, S.7
Kawazu, S.8
Nagai, R.9
-
42
-
-
0242406744
-
Mechanisms of Hypoxic Regulation of Plasminogen Activator Inhibitor-1 Gene Expression in Keloid Fibroblasts
-
in press
-
Zhang QZ, Wu YD, Ann DK, Messadi DV, Tuan TL, Kelly AP, Bertolami CN and Le AD. 2003. Mechanisms of Hypoxic Regulation of Plasminogen Activator Inhibitor-1 Gene Expression in Keloid Fibroblasts. J Invest Dermatol, in press.
-
(2003)
J Invest Dermatol
-
-
Zhang, Q.Z.1
Wu, Y.D.2
Ann, D.K.3
Messadi, D.V.4
Tuan, T.L.5
Kelly, A.P.6
Bertolami, C.N.7
Le, A.D.8
-
43
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. 2000. Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541-1545.
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
|