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Volumn 199, Issue 1, 2004, Pages 89-97

Crosstalk of Hypoxia-Mediated Signaling Pathways in Upregulating Plasminogen Activator Inhibitor-1 Expression in Keloid Fibroblasts

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; GENISTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN KINASE B; PROTEIN TYROSINE KINASE;

EID: 1042291174     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10452     Document Type: Article
Times cited : (57)

References (43)
  • 1
    • 0031754373 scopus 로고    scopus 로고
    • Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor-1 activity
    • Agani F and Semenza GL. 1998. Mersalyl is a novel inducer of vascular endothelial growth factor gene expression and hypoxia-inducible factor-1 activity. Mol Pharmacol 54:749-754.
    • (1998) Mol Pharmacol , vol.54 , pp. 749-754
    • Agani, F.1    Semenza, G.L.2
  • 3
    • 0033981473 scopus 로고    scopus 로고
    • The plasminogen activation system in tumor growth, invasion, and metastasis
    • Andreasen PA, Egelund R, Petersen HH. 2000. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell Mol Life Sci 57:25-40.
    • (2000) Cell Mol Life Sci , vol.57 , pp. 25-40
    • Andreasen, P.A.1    Egelund, R.2    Petersen, H.H.3
  • 4
    • 0035107345 scopus 로고    scopus 로고
    • Hypoxia activates Akt and induces phosphorylation of GSK-1 in PC12 cells
    • Beitner-Johnson D, Rust RT, Hsieh TC, Millhorn DE. 2001. Hypoxia activates Akt and induces phosphorylation of GSK-1 in PC12 cells. Cell Signal 13:23-27.
    • (2001) Cell Signal , vol.13 , pp. 23-27
    • Beitner-Johnson, D.1    Rust, R.T.2    Hsieh, T.C.3    Millhorn, D.E.4
  • 5
    • 0035866784 scopus 로고    scopus 로고
    • Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation
    • Chen EY, Mazure NM, Cooper JA, Giacia AJ. 2001. Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation. Cancer Res 61:2429-2433.
    • (2001) Cancer Res , vol.61 , pp. 2429-2433
    • Chen, E.Y.1    Mazure, N.M.2    Cooper, J.A.3    Giacia, A.J.4
  • 6
    • 0033664260 scopus 로고    scopus 로고
    • Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblast
    • Chin GS, Liu W, Steinbrech D, Hsu M, Levinson H, Longaker MT. 2000. Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblast. Plast Reconstr Surg 106:1532-1540.
    • (2000) Plast Reconstr Surg , vol.106 , pp. 1532-1540
    • Chin, G.S.1    Liu, W.2    Steinbrech, D.3    Hsu, M.4    Levinson, H.5    Longaker, M.T.6
  • 8
    • 0031057091 scopus 로고    scopus 로고
    • Hypoxia regulates the expression of vascular permiability factor/ vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin
    • Detmar M, Brown LF, Berse B, Jackman RW, Elicker BM, Dvorak. 1997. Hypoxia regulates the expression of vascular permiability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin. J Invest Dermatol 108:263-268.
    • (1997) J Invest Dermatol , vol.108 , pp. 263-268
    • Detmar, M.1    Brown, L.F.2    Berse, B.3    Jackman, R.W.4    Elicker, B.M.5    Dvorak6
  • 9
    • 0038757584 scopus 로고    scopus 로고
    • Akt activation by reactive oxygen species is independent from tyrosine kinase receptor phosphorylation and requires Src activity
    • Esposito F, Chirico G, Gesualdi NM, Posadas I, Ammendola R, Russo T, Cirino G and Cimino F. 2003. Akt activation by reactive oxygen species is independent from tyrosine kinase receptor phosphorylation and requires Src activity. J Biol Chem 278:20828-20834.
    • (2003) J Biol Chem , vol.278 , pp. 20828-20834
    • Esposito, F.1    Chirico, G.2    Gesualdi, N.M.3    Posadas, I.4    Ammendola, R.5    Russo, T.6    Cirino, G.7    Cimino, F.8
  • 10
    • 0035087539 scopus 로고    scopus 로고
    • Quantitative gene expression profiles of human liver-derived cell lines exposed to moderate hypoxia
    • Fink T, Ebbesen P, Zachar V. 2001. Quantitative gene expression profiles of human liver-derived cell lines exposed to moderate hypoxia. Cell Physiol Biochem. 11:105-114.
    • (2001) Cell Physiol Biochem , vol.11 , pp. 105-114
    • Fink, T.1    Ebbesen, P.2    Zachar, V.3
  • 11
    • 0037085780 scopus 로고    scopus 로고
    • Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1
    • Fink T, Kazlauskas A, Poellinger L, Ebbesen P, Zachar V. 2002. Identification of a tightly regulated hypoxia-response element in the promoter of human plasminogen activator inhibitor-1. Blood 99:2077-2083.
    • (2002) Blood , vol.99 , pp. 2077-2083
    • Fink, T.1    Kazlauskas, A.2    Poellinger, L.3    Ebbesen, P.4    Zachar, V.5
  • 12
    • 0031797364 scopus 로고    scopus 로고
    • Stimulation of plasminogen activator inhobitor-1 expression in immortalized human trophoblast cells cultured under low levels of oxygen
    • Fitzpatrick TE, Graham CH. 1998. Stimulation of plasminogen activator inhobitor-1 expression in immortalized human trophoblast cells cultured under low levels of oxygen. Exp Cell Res 245:155-162.
    • (1998) Exp Cell Res , vol.245 , pp. 155-162
    • Fitzpatrick, T.E.1    Graham, C.H.2
  • 13
    • 0037224827 scopus 로고    scopus 로고
    • Genistein activates p38 Map kinases, inactivates ERK1/2 and decreases Cdc25C expression in immortalized human mammary epithelial cells
    • Frey RS, Singletary KW. 2003. Genistein activates p38 Map kinases, inactivates ERK1/2 and decreases Cdc25C expression in immortalized human mammary epithelial cells. J Nutr 133:226-231.
    • (2003) J Nutr , vol.133 , pp. 226-231
    • Frey, R.S.1    Singletary, K.W.2
  • 14
    • 0033134112 scopus 로고    scopus 로고
    • Differential regulation of PAI-1 gene expression in human fibroblasts predisposed to a fibric phenotype
    • Higgins PJ, Slack JK, Diegelmann RF, Staiano-Coico L. 1999. Differential regulation of PAI-1 gene expression in human fibroblasts predisposed to a fibric phenotype. Exp Cell Res 248:634-642.
    • (1999) Exp Cell Res , vol.248 , pp. 634-642
    • Higgins, P.J.1    Slack, J.K.2    Diegelmann, R.F.3    Staiano-Coico, L.4
  • 18
    • 0037067454 scopus 로고    scopus 로고
    • Hypoxic induction of hypoxia inducible factor is mediated via the adaptor protein Sch in endothelial cells
    • Jung F, Haendeler J, Hoffmann J, Reissner A, Dernbach E, Zeiher AM, Dimmeler S. 2002. Hypoxic induction of hypoxia inducible factor is mediated via the adaptor protein Sch in endothelial cells. Cir Res 91:38-45.
    • (2002) Cir Res , vol.91 , pp. 38-45
    • Jung, F.1    Haendeler, J.2    Hoffmann, J.3    Reissner, A.4    Dernbach, E.5    Zeiher, A.M.6    Dimmeler, S.7
  • 19
    • 0032795850 scopus 로고    scopus 로고
    • Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes
    • Kietzmann T, Roth U, Jungermann K. 1999. Induction of the plasminogen activator inhibitor-1 gene expression by mild hypoxia via a hypoxia response element binding the hypoxia-inducible factor-1 in rat hepatocytes. Blood 94:4177-4185.
    • (1999) Blood , vol.94 , pp. 4177-4185
    • Kietzmann, T.1    Roth, U.2    Jungermann, K.3
  • 20
    • 0037391958 scopus 로고    scopus 로고
    • Regulation of the hypoxia-dependent Plasminogen activator inhibitor 1 expression by MAP kinases
    • Kietzmann T, Jungermann K, Görlach A. 2003. Regulation of the hypoxia-dependent Plasminogen activator inhibitor 1 expression by MAP kinases. Thromb Haemost 89:666-673.
    • (2003) Thromb Haemost , vol.89 , pp. 666-673
    • Kietzmann, T.1    Jungermann, K.2    Görlach, A.3
  • 21
    • 0026843757 scopus 로고
    • The microvessels in hypertrophic scars, keloids and related lesions: A review
    • Kischer CW. 1992. The microvessels in hypertrophic scars, keloids and related lesions: A review. J Submicrosc Cytol Pathol 24:281-296.
    • (1992) J Submicrosc Cytol Pathol , vol.24 , pp. 281-296
    • Kischer, C.W.1
  • 22
    • 0019939174 scopus 로고
    • Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids
    • Kischer CW, Thies AC, Chvapil M. 1982. Perivascular myofibroblasts and microvascular occlusion in hypertrophic scars and keloids. Human Pathol 13:819-824.
    • (1982) Human Pathol , vol.13 , pp. 819-824
    • Kischer, C.W.1    Thies, A.C.2    Chvapil, M.3
  • 24
    • 0030869787 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinas/Akt signaling pathway in Ha-rastransformed cells through a hypoxia inducible factor-1 transcriptional element
    • Mazure N, Chen Y, Laderoute K, Giaccia A. 1997. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinas/Akt signaling pathway in Ha-rastransformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 90:3322-3331.
    • (1997) Blood , vol.90 , pp. 3322-3331
    • Mazure, N.1    Chen, Y.2    Laderoute, K.3    Giaccia, A.4
  • 25
    • 0032541029 scopus 로고    scopus 로고
    • p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
    • Milanini J, Viñals F, Pouysségur J, Pagès G. 1998. p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts. J Biol Chem 273:18165-18172.
    • (1998) J Biol Chem , vol.273 , pp. 18165-18172
    • Milanini, J.1    Viñals, F.2    Pouysségur, J.3    Pagès, G.4
  • 27
    • 0035478294 scopus 로고    scopus 로고
    • Transduction pathways involved in hypoxia-inducible factor phosphorylation and activation
    • Minet E, Michel G, Mottet D, Raes M and Michiels C. 2001. Transduction pathways involved in hypoxia-inducible factor phosphorylation and activation. Free Radic Biol Med 31:847-855.
    • (2001) Free Radic Biol Med , vol.31 , pp. 847-855
    • Minet, E.1    Michel, G.2    Mottet, D.3    Raes, M.4    Michiels, C.5
  • 28
    • 0029068339 scopus 로고
    • Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
    • Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. 1995. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 375:577-581.
    • (1995) Nature , vol.375 , pp. 577-581
    • Mukhopadhyay, D.1    Tsiokas, L.2    Zhou, X.M.3    Foster, D.4    Brugge, J.S.5    Sukhatme, V.P.6
  • 30
    • 0032167429 scopus 로고    scopus 로고
    • Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition
    • Pinsky DJ, Liao H, Lawson CA, Yan SF, Chen JX, Carmeliet P, Loskutoff DJ. 1998. Coordinated induction of plasminogen activator inhibitor-1 (PAI-1) and inhibition of plasminogen activator gene expression by hypoxia promotes pulmonary vascular fibrin deposition. J Clin Invest 102:919-928.
    • (1998) J Clin Invest , vol.102 , pp. 919-928
    • Pinsky, D.J.1    Liao, H.2    Lawson, C.A.3    Yan, S.F.4    Chen, J.X.5    Carmeliet, P.6    Loskutoff, D.J.7
  • 31
    • 0030989114 scopus 로고    scopus 로고
    • Protein tyrosine kinases activity is required for oxidant-induced extracellular signal-regulated protein kinase activation and c-fos/c-jun expression
    • Rao GN. 1997. Protein tyrosine kinases activity is required for oxidant-induced extracellular signal-regulated protein kinase activation and c-fos/c-jun expression. Cell Signal 9:181-187.
    • (1997) Cell Signal , vol.9 , pp. 181-187
    • Rao, G.N.1
  • 32
    • 0032725554 scopus 로고    scopus 로고
    • p42/44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor-1alpha and enhance the transcriptional activity of HIF-1
    • Richard DE, Berra E, Gothie, Roux D, Pouyssegur J. 1999. p42/44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor-1alpha and enhance the transcriptional activity of HIF-1. J Biol Chem 274:32631-32637.
    • (1999) J Biol Chem , vol.274 , pp. 32631-32637
    • Richard, D.E.1    Berra, E.2    Gothie3    Roux, D.4    Pouyssegur, J.5
  • 33
    • 0034282388 scopus 로고    scopus 로고
    • Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells
    • Richard DE, Berra E, and Pouyssegur J. 2000. Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells. J Biol Chem 275:26765-26771.
    • (2000) J Biol Chem , vol.275 , pp. 26765-26771
    • Richard, D.E.1    Berra, E.2    Pouyssegur, J.3
  • 34
    • 0037227385 scopus 로고    scopus 로고
    • Modulation of the expression of tissue Plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts
    • Saed GM, Diamond MP. 2003. Modulation of the expression of tissue Plasminogen activator and its inhibitor by hypoxia in human peritoneal and adhesion fibroblasts. Fert Steril 79:164-168.
    • (2003) Fert Steril , vol.79 , pp. 164-168
    • Saed, G.M.1    Diamond, M.P.2
  • 35
    • 0031038419 scopus 로고    scopus 로고
    • Complex role of protein phosphorylation in gene activation by hypoxia
    • Salceda S, Beck I, Srinivas V and Caro J. 1997. Complex role of protein phosphorylation in gene activation by hypoxia. Kidney Int 51:556-559.
    • (1997) Kidney Int , vol.51 , pp. 556-559
    • Salceda, S.1    Beck, I.2    Srinivas, V.3    Caro, J.4
  • 36
    • 0036710591 scopus 로고    scopus 로고
    • Signal transduction to hypoxia-inducible factor 1
    • Semenza GL. 2002. Signal transduction to hypoxia-inducible factor 1. Biochem Pharmacol 64:993-998.
    • (2002) Biochem Pharmacol , vol.64 , pp. 993-998
    • Semenza, G.L.1
  • 37
    • 0035860246 scopus 로고    scopus 로고
    • MAPK and Akt act cooperatively but independently on hypoxia inducible factor 1alpha in rasV12 upregulation of VEGF
    • Sodhi A, Montaner S, Miyazaki H, Gutkind JS. 2001. MAPK and Akt act cooperatively but independently on hypoxia inducible factor 1alpha in rasV12 upregulation of VEGF. Biochem Biophys Res Commun 287:292-300.
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 292-300
    • Sodhi, A.1    Montaner, S.2    Miyazaki, H.3    Gutkind, J.S.4
  • 40
    • 0037408433 scopus 로고    scopus 로고
    • Increased plasminogen activator inhibitor-1 in keloid fibroblasts may account for their elevated collagen accumulation in fibrin gel cultures
    • Tuan TL, Wu HY, Hang EY, Chong SN, Laug W, Messadi D, Kelley P, and Le A. 2003. Increased plasminogen activator inhibitor-1 in keloid fibroblasts may account for their elevated collagen accumulation in fibrin gel cultures. Am J Patholol 162:1579-1589.
    • (2003) Am J Patholol , vol.162 , pp. 1579-1589
    • Tuan, T.L.1    Wu, H.Y.2    Hang, E.Y.3    Chong, S.N.4    Laug, W.5    Messadi, D.6    Kelley, P.7    Le, A.8
  • 41
    • 0034032489 scopus 로고    scopus 로고
    • Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through genistein-sensitive tyrosine kinase pathways in vascular endothelial cells
    • Uchiyama T, Kurabayashi M, Ohyama Y, Utsugi T, Akuzawa N, Sato M, Tomono S, Kawazu S, Nagai R. 2000. Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through genistein-sensitive tyrosine kinase pathways in vascular endothelial cells. Arterioscler Thromb Vasc Biol 20:1155-1161.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1155-1161
    • Uchiyama, T.1    Kurabayashi, M.2    Ohyama, Y.3    Utsugi, T.4    Akuzawa, N.5    Sato, M.6    Tomono, S.7    Kawazu, S.8    Nagai, R.9
  • 43
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL. 2000. Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541-1545.
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3    Laughner, E.4    Hanrahan, C.5    Georgescu, M.M.6    Simons, J.W.7    Semenza, G.L.8


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