NSAID-related psychiatric adverse events: Who is at risk?

Drugs

Volumn 64, Issue 23, 2004, Pages 2619-2627

  Onder, Graziano ^a,b,d   Pellicciotti, Francesca ^a   Gambassi, Giovanni ^a,c   Bernabei, Roberto ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c BROWN UNIVERSITY   (United States)

^d FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; DICLOFENAC; DOPAMINE; IBUPROFEN; INDOMETACIN; NAPROXEN; NEUROTRANSMITTER; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PROSTAGLANDIN; ROFECOXIB; SULINDAC; TOLMETIN;

ADULT; AGED; AGITATION; AMNESIA; ANXIETY DISORDER; CELL SPECIFICITY; CENTRAL NERVOUS SYSTEM DISEASE; CHILDBIRTH; COGNITIVE DEFECT; CONFUSION; DELIRIUM; DENDRITE; DENDRITIC SPINE; DEPERSONALIZATION; DEPRESSION; DISEASE EXACERBATION; DISORIENTATION; DIZZINESS; DREAMING; DRUG SELECTIVITY; DYSPHORIA; DYSPNEA; EMOTIONAL DISORDER; ENZYME LOCALIZATION; FEAR; FEMALE; HALLUCINATION; HIGH RISK POPULATION; HUMAN; HYPOMANIA; INCIDENCE; INSOMNIA; IRRITABILITY; LETHARGY; MALAISE; MALE; MANIA; MENTAL DISEASE; MOOD DISORDER; MORBIDITY; MORTALITY; MOTOR DYSFUNCTION; NEUROTRANSMISSION; PANIC; PARANOIA; PROSTAGLANDIN SYNTHESIS; PSEUDODEMENTIA; PSYCHOSIS; PUERPERIUM; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; SLEEP DISORDER; SOMNOLENCE; SYMPTOMATOLOGY; SYNAPTIC TRANSMISSION; THOUGHT DISORDER;

ADULT; ADVERSE DRUG REACTION REPORTING SYSTEMS; AGE DISTRIBUTION; AGED; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOOXYGENASE INHIBITORS; FEMALE; HUMANS; INCIDENCE; MALE; MENTAL DISORDERS; MIDDLE AGED; RISK FACTORS; SEX DISTRIBUTION;

EID: 10344256153     PISSN: 00126667     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003495-200464230-00001     Document Type: Review

References (62)

1. Jones R. Nonsteroidal anti-inflammatory drug prescribing: past, present, and future. Am J Med 2001 Jan 8; 110 (1A): 4S-7S
2. Paulose-Ram R, Hirsch R. Dillon C, et al. Prescription and nonprescription analgesic use among the US adult population: results from the third National Health and Nutrition Examination Survey (NHANES III). Pharmacoepidemiol Drug Saf 2003 Jun; 12 (4): 315-26
3. Lipsky PE. The role of COX-2-specific inhibitors in clinical practice. Am J Med 2001 Feb 19; 110 Suppl. 3A: 1S-2S
4. Vane JR, Bolting RM. Mechanism of action of antiinflammatory drugs. Int J Tissue React 1998; 20 (1): 3-15
5. Konstan MW, Byard PJ, Hoppel CL, et al. Effect of high-dose ibuprofen in patients with cystic fibrosis. N Engl J Med 1995 Mar 30; 332 (13): 848-54
6. Langman MJ, Cheng KK, Oilman EA, et al. Effect of antiinflammatory drugs on overall risk of common cancer: case-control study in general practice research database. BMJ 2000 Jun 17; 320 (7250): 1642-6
7. Onder G, Penninx BW, Landi F, et al. Depression and adverse drug reactions among hospitalized older adults. Arch Intern Med 2003 Feb 10; 163 (3): 301-5
8. Onder G, Pedone C, Landi F, et al. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 2002 Dec; 50 (12): 1962-8
9. Rodriguez-Monguio R, Otero M, Rovira J. Assessing the economic impact of adverse drug effects. Pharmacoeconomics 2003; 21 (9): 623-50
10. Johnson AG, Day RO. The problems and pitfalls of NSAID therapy in the elderly (Pt I). Drugs Aging 1991 Mar; 1 (2): 130-43
11. Pilotto A, Franceschi M, Leandro G, et al. NSAID and aspirin use by the elderly in general practice: effect on gastrointestinal symptoms and therapies. Drugs Aging 2003; 20 (9): 701-10
12. Griffin MR, Yared A, Ray WA. Nonsteroidal antiinflammatory drugs and acute renal failure in elderly persons. Am J Epidemiol 2000 Mar 1; 151 (5): 488-96
13. Bleumink GS, Feenstra J, Sturkenboom MC, et al. Nonsteroidal anti-inflammatory drugs and heart failure. Drugs 2003; 63 (6): 525-34
14. Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 2001 Aug 22-29; 286 (8): 954-9
15. Jiang HK, Chang DM. Non-steroidal anti-inflammatory drugs with adverse psychiatric reactions: five case reports. Clin Rheumatol 1999; 18 (4): 339-45
16. Clark DW, Ghose K. Neuropsychiatric reactions to nonsteroidal anti-inflammatory drugs (NSAIDs): the New Zealand experience. Drug Saf 1992 Nov-Dec; 7 (6): 460-5
17. Clunie M, Crone LA, Klassen L, et al. Psychiatric side effects of indomethacin in parturients. Can J Anaesth 2003 Jun-Jul; 50 (6): 586-8
18. Celecoxib (Celebrex™): 1 year later. Canadian ADR Newsletter 2000 Apr; 10 (2): 1-3
19. Coulter D. Acute psychiatric reactions with cox-2 inhibitors. Prescriber Update 2002 Jul; 23 (2): 21
20. Acute neuropsychiatric events with celecoxib and rofecoxib. Aust Adv Drug Reactions Bull 2003; 22 (1): 3
21. Boyle AC. Indomethacin and peptic ulcer [letter], BMJ 1965 May 1; 5443: 1191
22. Rothermich NO. An extended study of indomethacin. I: clinical pharmacology. JAMA 1966 Feb 14; 195 (7): 531-6
23. Thompson M, Percy JS. Further experience with indomethacin in the treatment of rheumatic disorders. BMJ 1966 Jan 8; 5479: 80-3
24. Carney MW. Paranoid psychosis with indomethacin. BMJ 1977 Oct 15; 2 (6093): 994-5
25. Gotz V. Paranoid psychosis with indomethacin [letter], BMJ 1978 Jan 7; 1 (6104): 49
26. Kruis R, Barger R. Paranoid psychosis with sulindac [letter]. JAMA 1980 Apr 11; 243 (14): 1420
27. Thornton TL. Delirium associated with sulindac [letter], JAMA 1980 Apr 25; 243 (16): 1630-1
28. Goodwin JS, Regan M. Cognitive dysfunction associated with naproxen and ibuprofen in the elderly. Arthritis Rheum 1982 Aug; 25 (8): 1013-5
29. Griffith JD, Smith CH, Smith RC. Paranoid psychosis in a patient receiving ibuprofen, a prostaglandin synthesis inhibitor: case report. J Clin Psychiatry 1982 Dec; 43 (12): 499-500
30. Schwartz JI, Moura RJ. Severe depersonalization and anxiety associated with indomethacin. South Med J 1983 May; 76 (5): 679-80
31. Sotsky SM, Tossell JW. Tolmetin induction of mania. Psychosomatics 1984 Aug; 25 (8): 626-8
32. Browning CH. Nonsteroidal anti-inflammatory drugs and severe psychiatric side effects. Int J Psychiatry Med 1996; 26 (1): 25-34
33. Mallet L, Kuyumjian J. Indomethacin-induced behavioral changes in an elderly patient with dementia. Ann Pharmacother 1998 Feb; 32 (2): 201-3
34. Ritter A, Eskin B. Ibuprofen overdose presenting with severe agitation and hypothermia. Am J Emerg Med 1998 Sep; 16 (5): 549-50
35. Nassif JM, Ritter MA. Indomethacin-induced postoperative psychosis. J Arthroplasty 1999 Sep; 14 (6): 769-70
36. Tharumaratnam D, Bashford S, Khan SA. Indomethacin induced psychosis. Postgrad Med J 2000 Nov; 76 (901): 736-7
37. Lantz MS, Giambanco V. Acute onset of auditory hallucinations after initiation of celecoxib therapy. Am J Psychiatry 2000 Jun; 157 (6): 1022-3
38. Macknight C, Rojas-Fernandez CH. Celecoxib- and rofecoxib-induced delirium. J Neuropsychiatry Clin Neurosci 2001 Spring; 13 (2): 305-6
39. Katz N, Zemishlany Z, Weizman A. Ibuprofen and psychotic exacerbation. Am J Psychiatry 2002 Sep 1; 159 (9): 1606-7
40. Bernstein AL, Werlin A. Pseudodementia associated with use of ibuprofen. Ann Pharmacother 2003 Jan; 37 (1): 80-2
41. Eser D, Zwanzger P, Rupprecht R. Carbamazepine treatment of adverse psychiatric effects after treatment with the nonsteroidal anti-inflammatory drug piroxicam. J Clin Psychiatry 2003 Jul; 64 (7): 852-4
42. Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 and 2. Annu Rev Pharmacol Toxicol 1998; 38: 97-120
43. Kaufmann WE, Andreasson KI, Isakson PC, et al. Cyclooxygenases and the central nervous system. Prostaglandins 1997 Sep; 54 (3): 601-24
44. Horrobin DF. The roles of prostaglandins and prolactin in depression, mania and schizophrenia. Postgrad Med J 1977; 53 Suppl. 4: 160-5
45. Horrobin DF, Manku MS. Possible role of prostaglandin El in the affective disorders and in alcoholism. BMJ 1980 Jun 7; 280 (6228): 1363-6
46. Laruelle M, Abi-Dargham A, Gil R, et al. Increased dopamine transmission in schizophrenia: relationship to illness phases. Biol Psychiatry 1999 Jul 1; 46 (1): 56-72
47. Ellison G. Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula. Brain Res Brain Res Rev 1994 May; 19 (2): 223-39
48. Ross BM, Brooks RJ, Lee M, et al. Cyclooxygenase inhibitor modulation of dopamine-related behaviours. Eur J Pharmacol 2002 Aug 23; 450 (2): 141-51
49. van Kammen DP, Yao JK, Goetz K. Polyunsaturated fatty acids, prostaglandins, and schizophrenia. Ann N Y Acad Sci 1989; 559: 411-23
50. Kaiya H, Imai H, Muramatsu Y, et al. Platelet aggregation response in schizophrenia and prostaglandin E1. Psychiatry Res 1983 Aug; 9 (4); 309-18
51. Vaddadi K. Dyskinesias and their treatment with essential fatty acids: a review. Prostaglandins Leukot Essent Fatty Acids 1996 Aug; 55 (1-2): 89-94
52. Kanof PD, Davidson M, Johns CA, et al. Clinical correlates of platelet prostaglandin receptor subsensitivity in schizophrenia. Am J Psychiatry 1987 Dec; 144 (12): 1556-60
53. Vinogradov S, Csernansky JG. Postpartum psychosis with abnormal movements: dopamine supersensitivity unmasked by withdrawal of endogenous estrogens? J Clin Psychiatry 1990 Sep; 51 (9): 365-6
54. Fink G, Sumner BE, Rosie R, et al. Estrogen control of central neurotransmission: effect on mood, mental state, and memory. Cell Mol Neurobiol 1996 Jun; 16 (3): 325-44
55. Haag M. Essential fatty acids and the brain. Can J Psychiatry 2003 Apr; 48 (3): 195-203
56. Hoppmann RA, Peden JG, Ober SK. Central nervous system side effects of nonsteroidal anti-inflammatory drugs: aseptic meningitis, psychosis, and cognitive dysfunction. Arch Intern Med 1991 Jul; 151 (7): 1309-13
57. Seideman P, von Arbin M. Cerebral blood flow and indomethacin drug levels in subjects with and without central nervous side effects. Br J Clin Pharmacol 1991 Apr; 31 (4): 429-32
58. Onder G, Gambassi G, Scales CJ, et al. Adverse drug reactions and cognitive function among hospitalized older adults. Eur J Clin Pharmacol 2002 Aug; 58 (5): 371-7
59. Beers MH. Explicit criteria for determining potentially inappropriate medication use by the elderly: an update. Arch Intern Med 1997 Jul 28; 157 (14): 1531-6
60. Onder G, Landi F, Cesari M, et al. Inappropriate medication use among hospitalized older adults in Italy: results from the Italian Group of Pharmacoepidemiology in the Elderly. Eur J Clin Pharmacol 2003 Jun; 59 (2): 157-62
61. Warner TD, Giuliano F, Vojnovic I, et al. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci U S A 1999 Jun 22; 96 (13): 7563-8
62. Muller N, Riedel M, Scheppach C, et al. Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia. Am J Psychiatry 2002 Jun; 159 (6): 1029-34