Inhibition of activator protein 1 by barbiturates is mediated by differential effects on mitogen-activated protein kinases and the small G proteins ras and rac-1

Journal of Pharmacology and Experimental Therapeutics

Volumn 311, Issue 3, 2004, Pages 1232-1240

  Humar, Matjaz ^a   Andriopoulos, Nikolaos ^a   Pischke, Soeren E ^a   Loop, Torsten ^a   Schmidt, Rene ^a   Hoetzel, Alexander ^a   Roesslein, Martin ^a   Pahl, Heike L ^a   Geiger, Klaus K ^a   Pannen, Benedikt H J ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BARBITURIC ACID DERIVATIVE; CALCIUM; CD28 ANTIGEN; CD3 ANTIGEN; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; METHOHEXITAL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PENTOBARBITAL; PHORBOL 13 ACETATE 12 MYRISTATE; RAC1 PROTEIN; RAF PROTEIN; RAS PROTEIN; SECOBARBITAL; THIAMYLAL; THIOBARBITURIC ACID; THIOPENTAL; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NFAT;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG PROTEIN BINDING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HOSPITAL INFECTION; HUMAN; HUMAN CELL; IMMUNOREGULATION; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; T LYMPHOCYTE; TRANSCRIPTION REGULATION;

ANTIGENS, CD3; BARBITURATES; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENES, REPORTER; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUCIFERASES; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROPEPTIDES; NUCLEAR PROTEINS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-JUN; PROTO-ONCOGENE PROTEINS P21(RAS); RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN; RAS PROTEINS; T-LYMPHOCYTES; TRANSCRIPTION FACTOR AP-1;

EID: 10044287111     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.071332     Document Type: Article

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