메뉴 건너뛰기




Volumn 17, Issue 6, 2004, Pages 663-673

Non-cytotoxic drugs as potential treatments for gliomas

Author keywords

Angiogenesis; Intratumoral therapy; Malignant gliomas; Targeted molecular therapy

Indexed keywords

4 (4 FLUORO 2 METHYL 5 INDOLYLOXY) 6 METHOXY 7 [3 (1 PYRROLIDINYL)PROPOXY]QUINAZOLINE; 5,6,7,13 TETRAHYDRO 12 (3 HYDROXYPROPYL) 9 ISOPROPOXYMETHYLINDENO[2,1 A]PYRROLO[3,4 C]CARBAZOL 5(12H) ONE DIMETHYLGLYCINE ESTER; 6 [4 (4 ETHYL 1 PIPERAZINYLMETHYL)PHENYL] 4 (ALPHA METHYLBENZYLAMINO) 7H PYRROLO[2,3 D]PYRIMIDINE; ANTINEOPLASTIC AGENT; AP 12009; AP 23573; CARMUSTINE; CILENGITIDE; DEPSIPEPTIDE; ENZASTAURIN; ERLOTINIB; EVEROLIMUS; GEFITINIB; HISTONE DEACETYLASE INHIBITOR; IMATINIB; LAPATINIB; LENALIDOMIDE; LOMUSTINE; LONAFARNIB; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR; RAPAMYCIN; RETINOID DERIVATIVE; SEMAXANIB; SI 27; SORAFENIB; SUNITINIB; TAMOXIFEN; TEMOZOLOMIDE; TEMSIROLIMUS; THALIDOMIDE; TIPIFARNIB; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VANDETANIB; VASCULOTROPIN INHIBITOR; VATALANIB; VORINOSTAT;

EID: 10044265497     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-200412000-00005     Document Type: Review
Times cited : (9)

References (99)
  • 1
    • 0037672568 scopus 로고    scopus 로고
    • Recent advances in the molecular genetics of primary gliomas
    • Kitange GJ, Templeton KL, Jenkins RB. Recent advances in the molecular genetics of primary gliomas. Curr Opin Oncol 2003; 15:197-203.
    • (2003) Curr Opin Oncol , vol.15 , pp. 197-203
    • Kitange, G.J.1    Templeton, K.L.2    Jenkins, R.B.3
  • 3
    • 0037302119 scopus 로고    scopus 로고
    • Signaling pathways regulating gliomagenesis
    • Konopka G, Bonni A. Signaling pathways regulating gliomagenesis. Curr Mol Med 2003; 3:73-84. A recent review of signaling pathways in gliomas.
    • (2003) Curr Mol Med , vol.3 , pp. 73-84
    • Konopka, G.1    Bonni, A.2
  • 5
    • 3042634240 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors in cancer therapy
    • Madhusudan S, Ganesan TS. Tyrosine kinase inhibitors in cancer therapy. Clin Biochem 2004; 7:618-635.
    • (2004) Clin Biochem , vol.7 , pp. 618-635
    • Madhusudan, S.1    Ganesan, T.S.2
  • 6
    • 2542515478 scopus 로고    scopus 로고
    • Epidermal growth factor receptor antagonists: Novel therapy for the treatment of high-grade gliomas
    • Nathoo N, Goldlust S, Vogelbaum MA. Epidermal growth factor receptor antagonists: novel therapy for the treatment of high-grade gliomas. Neurosurgery 2004; 54:1480-1488.
    • (2004) Neurosurgery , vol.54 , pp. 1480-1488
    • Nathoo, N.1    Goldlust, S.2    Vogelbaum, M.A.3
  • 7
    • 0003532553 scopus 로고    scopus 로고
    • Tumours of the central nervous system: World Health Organization Classification of Tumors
    • Lyon: IARC Press
    • Kleihues P, Cavenee WK. Tumours of the central nervous system: World Health Organization Classification of Tumors. In: Pathology and genetics. Lyon: IARC Press; 2000.
    • (2000) Pathology and Genetics
    • Kleihues, P.1    Cavenee, W.K.2
  • 8
    • 0034987702 scopus 로고    scopus 로고
    • Malignant glioma: Genetics and biology of a grave matter
    • Maher EA, Furnari FB, Bachoo RM, et al. Malignant glioma: genetics and biology of a grave matter. Genes Dev 2001; 15:1311-1333.
    • (2001) Genes Dev , vol.15 , pp. 1311-1333
    • Maher, E.A.1    Furnari, F.B.2    Bachoo, R.M.3
  • 9
    • 1242270613 scopus 로고    scopus 로고
    • The contribution of epidermal growth factor receptor (EGFR) signaling pathway to radioresistance in human gliomas: A review of preclinical and correlative clinical data
    • Chakravarti A, Dicker A, Mehta M. The contribution of epidermal growth factor receptor (EGFR) signaling pathway to radioresistance in human gliomas: a review of preclinical and correlative clinical data. Int J Radial Oncol Biol Phys 2004; 58:927-931. A recent review of the role of EGFR in radiation resistance in gliomas and potential therapeutic strategies.
    • (2004) Int J Radial Oncol Biol Phys , vol.58 , pp. 927-931
    • Chakravarti, A.1    Dicker, A.2    Mehta, M.3
  • 10
    • 10744229118 scopus 로고    scopus 로고
    • Inverse correlation of epidermal growth factor receptor (EGFR) mRNA induction and suppression of anchorage-independent growth by OSI-774, an EGFR tyrosine kinase inhibitor, in glioblastoma multiforme cell lines
    • Halatsch M-E, Gehrke EE, Vougioukas VI, et al. Inverse correlation of epidermal growth factor receptor (EGFR) mRNA induction and suppression of anchorage-independent growth by OSI-774, an EGFR tyrosine kinase inhibitor, in glioblastoma multiforme cell lines. J Neurosurg 2004; 100:523-533.
    • (2004) J Neurosurg , vol.100 , pp. 523-533
    • Halatsch, M.-E.1    Gehrke, E.E.2    Vougioukas, V.I.3
  • 11
    • 16844384784 scopus 로고    scopus 로고
    • A phase II trial of OSI-774 (Tarceva) in patients (pts) with recurrent malignant gliomas (MG) not on EIAEDs
    • New Orleans, 4-8 June Abstract 1502
    • Raizer JJ, Abrey L, Wen P, et al. A phase II trial of OSI-774 (Tarceva) in patients (pts) with recurrent malignant gliomas (MG) not on EIAEDs. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1502].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Raizer, J.J.1    Abrey, L.2    Wen, P.3
  • 12
    • 0242286359 scopus 로고    scopus 로고
    • Phase I study of OSI-774 alone or with temozolomide in patients with malignant glioma
    • Chicago, IL, 31 May-3 June Abstract 394
    • Prados M, Chang S, Burton E, et al. Phase I study of OSI-774 alone or with temozolomide in patients with malignant glioma. In: Proceedings of the American Society of Clinical Oncology. Chicago, IL, 31 May-3 June 2003 [Abstract 394].
    • (2003) Proceedings of the American Society of Clinical Oncology
    • Prados, M.1    Chang, S.2    Burton, E.3
  • 13
    • 16844383318 scopus 로고    scopus 로고
    • Phase II trial of the EGFR tyrosine kinase inhibitor erlotinib for single-agent therapy of recurrent glioblastoma multiforme: Interim results
    • New Orleans, 4-8 June Abstract 1558
    • Vogelbaum MA, Peereboom D, Stevens G, et al. Phase II trial of the EGFR tyrosine kinase inhibitor erlotinib for single-agent therapy of recurrent glioblastoma multiforme: interim results. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1558].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Vogelbaum, M.A.1    Peereboom, D.2    Stevens, G.3
  • 14
    • 1842500007 scopus 로고    scopus 로고
    • Phase II trial of gefitinib in recurrent glioblastoma
    • Rich JN, Reardon DA, Peery T, et al. Phase II trial of gefitinib in recurrent glioblastoma. J Clin Oncol 2004; 22:133-142.
    • (2004) J Clin Oncol , vol.22 , pp. 133-142
    • Rich, J.N.1    Reardon, D.A.2    Peery, T.3
  • 15
    • 0032767387 scopus 로고    scopus 로고
    • Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
    • Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol 1999; 17:2572-2578.
    • (1999) J Clin Oncol , vol.17 , pp. 2572-2578
    • Wong, E.T.1    Hess, K.R.2    Gleason, M.J.3
  • 16
    • 0032855728 scopus 로고    scopus 로고
    • Multicenter phase II trial of temozolomide in patients with anaplastic astrocytomas or anaplastic oligoastrocytoma at first relapse
    • Yung WYK, Prados MD, Yaya TR, et al. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytomas or anaplastic oligoastrocytoma at first relapse. J Clin Oncol 1999; 17:2762-2777.
    • (1999) J Clin Oncol , vol.17 , pp. 2762-2777
    • Yung, W.Y.K.1    Prados, M.D.2    Yaya, T.R.3
  • 17
    • 0242349431 scopus 로고    scopus 로고
    • Phase I-II study of ZD-1839 for recurrent malignant gliomas and meningiomas progressing after radiation therapy
    • New Orleans, 4-8 June Abstract 1510
    • Lieberman F, Cloughesy T, Deangelis LM, et al. Phase I-II study of ZD-1839 for recurrent malignant gliomas and meningiomas progressing after radiation therapy. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1510].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Lieberman, F.1    Cloughesy, T.2    Deangelis, L.M.3
  • 18
    • 23944478922 scopus 로고    scopus 로고
    • Phase II study of ZD1839/Iressa® in patients with newly diagnosed grade 4 astrocytoma
    • New Orleans, 4-8 June Abstract 1505
    • Uhm JH, Ballman KV, Giannini JC, et al. Phase II study of ZD1839/Iressa® in patients with newly diagnosed grade 4 astrocytoma. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1505].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Uhm, J.H.1    Ballman, K.V.2    Giannini, J.C.3
  • 19
    • 0036681993 scopus 로고    scopus 로고
    • The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner
    • Chakravarti A, Chakladar A, Delaney MA, et al. The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner. Cancer Res 2002; 62:4307-4315.
    • (2002) Cancer Res , vol.62 , pp. 4307-4315
    • Chakravarti, A.1    Chakladar, A.2    Delaney, M.A.3
  • 20
    • 0242276128 scopus 로고    scopus 로고
    • Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas
    • Krishnan S, Rao RD, James CD, Sarkaria JN. Combination of epidermal growth factor receptor targeted therapy with radiation therapy for malignant gliomas. Front Biosci 2003; 8:e1-e13.
    • (2003) Front Biosci , vol.8
    • Krishnan, S.1    Rao, R.D.2    James, C.D.3    Sarkaria, J.N.4
  • 21
    • 0347824669 scopus 로고    scopus 로고
    • Phase I results from RTOG BR-0211, a phase I/II study of an oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), ZD 1839 (Iressa), with radiation therapy in glioblastoma multiforme (GBM)
    • Chakravarti A, Seiferheld W, Robbins I, et al. Phase I results from RTOG BR-0211, a phase I/II study of an oral epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), ZD 1839 (Iressa), with radiation therapy in glioblastoma multiforme (GBM). Int J Radiat Oncol Biol Phys 2003; 57 (2 Suppl.):S329.
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , Issue.2 SUPPL.
    • Chakravarti, A.1    Seiferheld, W.2    Robbins, I.3
  • 22
    • 0036769168 scopus 로고    scopus 로고
    • Imatinib: A selective tyrosine kinase inhibitor
    • Manley PW, Cowan-Jacob SW, Buchdunger E, et al. Imatinib: a selective tyrosine kinase inhibitor. Eur J Cancer 2002; 38 (Suppl. 5):S19-S27.
    • (2002) Eur J Cancer , vol.38 , Issue.5 SUPPL.
    • Manley, P.W.1    Cowan-Jacob, S.W.2    Buchdunger, E.3
  • 23
    • 0036769158 scopus 로고    scopus 로고
    • Pharmacology of imatinib (STI571)
    • Buchdunger E, O'Reilly T, Wood J. Pharmacology of imatinib (STI571). Eur J Cancer 2002; 38 (Suppl. 5) S28-S36.
    • (2002) Eur J Cancer , vol.38 , Issue.5 SUPPL.
    • Buchdunger, E.1    O'Reilly, T.2    Wood, J.3
  • 25
    • 0034665138 scopus 로고    scopus 로고
    • Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class
    • Kilic T, Alberta JA, Zdunek PR, et al. Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. Cancer Res 2000; 60:5143-5150.
    • (2000) Cancer Res , vol.60 , pp. 5143-5150
    • Kilic, T.1    Alberta, J.A.2    Zdunek, P.R.3
  • 26
    • 21244488791 scopus 로고    scopus 로고
    • Phase I/II study of imatinib mesylate (STI571) for patients with recurrent malignant gliomas (NABTC 99-08)
    • Toronto, Canada, 18-21 November
    • Wen PY, Yung WKA, Lamborn K, et al. Phase I/II study of imatinib mesylate (STI571) for patients with recurrent malignant gliomas (NABTC 99-08). Society for Neuro-Oncology, 9th Annual Meeting. Toronto, Canada, 18-21 November 2004.
    • (2004) Society for Neuro-Oncology, 9th Annual Meeting
    • Wen, P.Y.1    Yung, W.K.A.2    Lamborn, K.3
  • 27
    • 16844382189 scopus 로고    scopus 로고
    • Multicentre phase II study of imatinib mesylate in patients with recurrent glioblastoma: An EORTC: NDDG/ BTG Intergroup Study
    • New Orleans, 4-8 June Abstract 1501
    • Raymond E, Brandes A, Van Oosterom A, et al. Multicentre phase II study of imatinib mesylate in patients with recurrent glioblastoma: an EORTC: NDDG/ BTG Intergroup Study. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1501].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Raymond, E.1    Brandes, A.2    Van Oosterom, A.3
  • 28
    • 0032927688 scopus 로고    scopus 로고
    • The p21-Ras-signal transduction pathway and growth regulation in human high-grade gliomas
    • Bredel M, Pollack IF. The p21-Ras-signal transduction pathway and growth regulation in human high-grade gliomas. Brain Res Brain Res Rev 1999; 29:232-249.
    • (1999) Brain Res Brain Res Rev , vol.29 , pp. 232-249
    • Bredel, M.1    Pollack, I.F.2
  • 29
    • 0242382624 scopus 로고    scopus 로고
    • Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways
    • Newton HB. Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways. Expert Rev Anticancer Ther 2003; 3:595-614. A detailed review of targeted molecular therapy for growth factor receptors and the Ras/MAP kinase pathway.
    • (2003) Expert Rev Anticancer Ther , vol.3 , pp. 595-614
    • Newton, H.B.1
  • 30
    • 3142548393 scopus 로고    scopus 로고
    • Two phase Il trials of R115777 (Zarnestra®) in patients with recurrent glioblastoma multiforme: A comparison of patients on enzyme-inducing anti-epileptic drugs (EIAED) and not on EIAED at maximum tolerated dose respectively, a North American Brain Tumor Consortium (NATC) Report
    • Abstract TA-10
    • Cloughesy TF, Kuhn J, Wen P, et al. Two phase Il trials of R115777 (Zarnestra®) in patients with recurrent glioblastoma multiforme: a comparison of patients on enzyme-inducing anti-epileptic drugs (EIAED) and not on EIAED at maximum tolerated dose respectively, a North American Brain Tumor Consortium (NATC) Report. Neuro-Oncology 2003; 5:349 [Abstract TA-10].
    • (2003) Neuro-Oncology , vol.5 , pp. 349
    • Cloughesy, T.F.1    Kuhn, J.2    Wen, P.3
  • 31
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat Rev Cancer 2002; 2:489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 32
    • 1142287357 scopus 로고    scopus 로고
    • Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/ PTCH, and angiogenesis
    • Newton HB. Molecular neuro-oncology and the development of "targeted" therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/ PTCH, and angiogenesis. Expert Rev Anticancer Ther 2004; 4:105-128. A detailed review of targeted molecular therapy for PI3K pathway and anti-angiogenesis.
    • (2004) Expert Rev Anticancer Ther , vol.4 , pp. 105-128
    • Newton, H.B.1
  • 33
    • 5444260577 scopus 로고    scopus 로고
    • Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs
    • Chang SM, Kuhn J, Wen P, et al. Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs. Invest New Drugs 2004; 22:427-435.
    • (2004) Invest New Drugs , vol.22 , pp. 427-435
    • Chang, S.M.1    Kuhn, J.2    Wen, P.3
  • 34
    • 1142281547 scopus 로고    scopus 로고
    • Phase II/pharmacokinetic study of CCI-779 in recurrent glioblastoma multiforme
    • Society For Neuro-Oncology, 8th Annual Meeting 2003 Abstract TA-09
    • Chang S, Kuhn J, Wen P, et al. Phase II/pharmacokinetic study of CCI-779 in recurrent glioblastoma multiforme. Society For Neuro-Oncology, 8th Annual Meeting 2003. Neuro-Oncology 2003; 5:349 [Abstract TA-09].
    • (2003) Neuro-Oncology , vol.5 , pp. 349
    • Chang, S.1    Kuhn, J.2    Wen, P.3
  • 35
    • 0035755974 scopus 로고    scopus 로고
    • Histone deacetylases and cancer: Causes and therapies
    • Marks PA, Rifkind RA, Richon VM, et al. Histone deacetylases and cancer: causes and therapies. Nat Cancer Rev 2001; 1:194-202.
    • (2001) Nat Cancer Rev , vol.1 , pp. 194-202
    • Marks, P.A.1    Rifkind, R.A.2    Richon, V.M.3
  • 36
    • 0242610850 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA
    • Kim MS, Blake M, Baek JH, et al. Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA. Cancer Res 2003; 63:7291-7300.
    • (2003) Cancer Res , vol.63 , pp. 7291-7300
    • Kim, M.S.1    Blake, M.2    Baek, J.H.3
  • 37
    • 2342611150 scopus 로고    scopus 로고
    • Emerging molecular therapies for brain tumors
    • Van Meir EG, Bellail A, Phuphanich S. Emerging molecular therapies for brain tumors. Semin Oncol 2004; 31 (2 Suppl.):38-46.
    • (2004) Semin Oncol , vol.31 , Issue.2 SUPPL. , pp. 38-46
    • Van Meir, E.G.1    Bellail, A.2    Phuphanich, S.3
  • 39
    • 3042634486 scopus 로고    scopus 로고
    • Development of new drugs in angiogenesis
    • Ziehe M, Donnini S, Morbidelli L. Development of new drugs in angiogenesis. Curr Drug Targets 2004; 5:485-493. A recent review of anti-angiogenic drugs under evaluation.
    • (2004) Curr Drug Targets , vol.5 , pp. 485-493
    • Ziehe, M.1    Donnini, S.2    Morbidelli, L.3
  • 40
    • 0642336106 scopus 로고    scopus 로고
    • Angiogenesis in glioma: Molecular mechanisms and roadblocks to translation
    • Bogler O, Mikkelsen T. Angiogenesis in glioma: molecular mechanisms and roadblocks to translation. Cancer J 2003; 9:205-213. A recent review of anti-angiogenic therapy for gliomas.
    • (2003) Cancer J , vol.9 , pp. 205-213
    • Bogler, O.1    Mikkelsen, T.2
  • 41
    • 3543028023 scopus 로고    scopus 로고
    • PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptor tyrosine kinases, decreases glioma growth and vascularization
    • Goldbrunner RH, Bendszus M, Wood J, et al. PTK787/ZK222584, an inhibitor of vascular endothelial growth factor receptor tyrosine kinases, decreases glioma growth and vascularization. Neurosurgery 2004; 55:426-432.
    • (2004) Neurosurgery , vol.55 , pp. 426-432
    • Goldbrunner, R.H.1    Bendszus, M.2    Wood, J.3
  • 42
    • 5444231926 scopus 로고    scopus 로고
    • A phase I trial of PTK787/ZK 222584 (PTK/ZK), an oral VEGF tyrosine kinase inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM)
    • New Orleans, 4-8 June Abstract 1513
    • Readon D, Friedman H, Yung WKA, et al. A phase I trial of PTK787/ZK 222584 (PTK/ZK), an oral VEGF tyrosine kinase inhibitor, in combination with either temozolomide or lomustine for patients with recurrent glioblastoma multiforme (GBM). In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1513].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Readon, D.1    Friedman, H.2    Yung, W.K.A.3
  • 43
    • 5044240201 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor ZD6474 inhibits tumour growth in an intracerebral rat glioma model
    • Epub ahead of print
    • Sandstrom M, Johansson M, Andersson U. The tyrosine kinase inhibitor ZD6474 inhibits tumour growth in an intracerebral rat glioma model. Br J Cancer 2004; (Epub ahead of print).
    • (2004) Br J Cancer
    • Sandstrom, M.1    Johansson, M.2    Andersson, U.3
  • 44
    • 0141842637 scopus 로고    scopus 로고
    • CEP-7055: A novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models
    • Ruggeri B, Singh J, Gingrich D, et al. CEP-7055: a novel, orally active pan inhibitor of vascular endothelial growth factor receptor tyrosine kinases with potent antiangiogenic activity and antitumor efficacy in preclinical models. Cancer Res 2003; 63:5978-5991.
    • (2003) Cancer Res , vol.63 , pp. 5978-5991
    • Ruggeri, B.1    Singh, J.2    Gingrich, D.3
  • 45
    • 3142774878 scopus 로고    scopus 로고
    • AEE788: A dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
    • Traxler P, Allegrini PR, Brandt R, et al. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res 2004; 64:4931-4941.
    • (2004) Cancer Res , vol.64 , pp. 4931-4941
    • Traxler, P.1    Allegrini, P.R.2    Brandt, R.3
  • 47
    • 3543132551 scopus 로고    scopus 로고
    • Thalidomide prolongs disease stabilization after conventional therapy in patients with recurrent glioblastoma
    • Morabito A, Fanelli M, Carillio G, et al. Thalidomide prolongs disease stabilization after conventional therapy in patients with recurrent glioblastoma. Oncol Rep 2004; 11:93-95.
    • (2004) Oncol Rep , vol.11 , pp. 93-95
    • Morabito, A.1    Fanelli, M.2    Carillio, G.3
  • 48
    • 0033954292 scopus 로고    scopus 로고
    • Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
    • Fine HA, Figg WD, Jaeckle K, et al. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol 2000; 18:708-715.
    • (2000) J Clin Oncol , vol.18 , pp. 708-715
    • Fine, H.A.1    Figg, W.D.2    Jaeckle, K.3
  • 49
    • 0035191268 scopus 로고    scopus 로고
    • Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme
    • Marx GM, Pavlakis N, McCowatt S, et al. Phase II study of thalidomide in the treatment of recurrent glioblastoma multiforme. J Neurooncol 2001; 54:31-38.
    • (2001) J Neurooncol , vol.54 , pp. 31-38
    • Marx, G.M.1    Pavlakis, N.2    McCowatt, S.3
  • 50
    • 0037811745 scopus 로고    scopus 로고
    • Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas
    • Fine HA, Wen PY, Maher EA, et al. Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas. J Clin Oncol 2003; 21:2299-2304.
    • (2003) J Clin Oncol , vol.21 , pp. 2299-2304
    • Fine, H.A.1    Wen, P.Y.2    Maher, E.A.3
  • 51
    • 1842536794 scopus 로고    scopus 로고
    • Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme
    • Baumann F, Bjeljac M, Kollias SS, et al. Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme. J Neurooncol 2004; 67:191-200.
    • (2004) J Neurooncol , vol.67 , pp. 191-200
    • Baumann, F.1    Bjeljac, M.2    Kollias, S.S.3
  • 52
    • 5444251630 scopus 로고    scopus 로고
    • A phase II trial of temozolomide plus thalidomide (NABTC 99-04) for recurrent malignant glioma
    • Proceedings of the 5th Congress of the European Association for Neuro-Oncology
    • Groves MD, Tremont-Lukats IW, Conrad C, et al. A phase II trial of temozolomide plus thalidomide (NABTC 99-04) for recurrent malignant glioma. Proceedings of the 5th Congress of the European Association for Neuro-Oncology. Neuro-Oncology 2002; 4:341.
    • (2002) Neuro-Oncology , vol.4 , pp. 341
    • Groves, M.D.1    Tremont-Lukats, I.W.2    Conrad, C.3
  • 53
    • 2342634443 scopus 로고    scopus 로고
    • Inhibition of glioma angiogenesis and invasion by SI-27, an anti-matrix metalloproteinase agent in a rat brain tumor model
    • Yoshida D, Takahashi H, Teramoto A. Inhibition of glioma angiogenesis and invasion by SI-27, an anti-matrix metalloproteinase agent in a rat brain tumor model. Neurosurgery 2004; 54:1213-1220.
    • (2004) Neurosurgery , vol.54 , pp. 1213-1220
    • Yoshida, D.1    Takahashi, H.2    Teramoto, A.3
  • 54
    • 5444266690 scopus 로고    scopus 로고
    • A phase II trial of LY317615 in patients with recurrent high grade gliomas
    • New Orleans, 4-8 June Abstract 1511
    • Fine HA, Kim L, Royce C, et al. A phase II trial of LY317615 in patients with recurrent high grade gliomas. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1511].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Fine, H.A.1    Kim, L.2    Royce, C.3
  • 55
    • 0034161878 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activities of cyclooxygenaase-2 inhibitors
    • Masferrer JL, Leahy KM, Koki AT, et al. Antiangiogenic and antitumor activities of cyclooxygenaase-2 inhibitors. Cancer Res 2000; 60:1306-1311.
    • (2000) Cancer Res , vol.60 , pp. 1306-1311
    • Masferrer, J.L.1    Leahy, K.M.2    Koki, A.T.3
  • 56
    • 0034282530 scopus 로고    scopus 로고
    • Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398
    • Joki T, Heese O, Nikas DC, et al. Expression of cyclooxygenase 2 (COX-2) in human glioma and in vitro inhibition by a specific COX-2 inhibitor, NS-398. Cancer Res 2000; 60:4926-4931.
    • (2000) Cancer Res , vol.60 , pp. 4926-4931
    • Joki, T.1    Heese, O.2    Nikas, D.C.3
  • 57
    • 0035360795 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human gliomas: Prognostic significance and molecular correlations
    • Shono T, Tofilon PJ, Bruner JM, et al. Cyclooxygenase-2 expression in human gliomas: prognostic significance and molecular correlations. Cancer Res 2001; 61:4375-4381.
    • (2001) Cancer Res , vol.61 , pp. 4375-4381
    • Shono, T.1    Tofilon, P.J.2    Bruner, J.M.3
  • 58
    • 2942513159 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors in glioma therapy
    • Giglio P, Levin V. Cyclooxygenase-2 inhibitors in glioma therapy. Am J Ther 2004; 11:141-143.
    • (2004) Am J Ther , vol.11 , pp. 141-143
    • Giglio, P.1    Levin, V.2
  • 59
    • 0037312539 scopus 로고    scopus 로고
    • Microglia cyclooxygenase-2 activity in experimental gliomas: Possible role in cerebral edema formation
    • Badie B, Schartner JM, Hagar AR, et al. Microglia cyclooxygenase-2 activity in experimental gliomas: possible role in cerebral edema formation. Clin Cancer Res 2003; 9:872-877.
    • (2003) Clin Cancer Res , vol.9 , pp. 872-877
    • Badie, B.1    Schartner, J.M.2    Hagar, A.R.3
  • 60
    • 0142166330 scopus 로고    scopus 로고
    • Cannabinoids: Potential anticancer agents
    • Guzman M. Cannabinoids: potential anticancer agents. Nat Rev Cancer 2003; 3:745-755.
    • (2003) Nat Rev Cancer , vol.3 , pp. 745-755
    • Guzman, M.1
  • 61
    • 0035422139 scopus 로고    scopus 로고
    • Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor
    • Sanchez C, de Ceballos ML, del Pulgar TG, et al. Inhibition of glioma growth in vivo by selective activation of the CB(2) cannabinoid receptor. Cancer Res 2001; 61:5784-5789.
    • (2001) Cancer Res , vol.61 , pp. 5784-5789
    • Sanchez, C.1    De Ceballos, M.L.2    Del Pulgar, T.G.3
  • 62
    • 4143086166 scopus 로고    scopus 로고
    • Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas
    • Blazquez C, Gonzalez-Feria L, Alvarez L, et al. Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas. Cancer Res 2004; 64:5617-5623.
    • (2004) Cancer Res , vol.64 , pp. 5617-5623
    • Blazquez, C.1    Gonzalez-Feria, L.2    Alvarez, L.3
  • 63
    • 9144265679 scopus 로고    scopus 로고
    • Combined therapy with direct and indirect angiogenesis inhibition results in enhanced antiangiogenic and antitumor effects
    • Abdollahi A, Lipson KE, Sckell A, et al. Combined therapy with direct and indirect angiogenesis inhibition results in enhanced antiangiogenic and antitumor effects. Cancer Res 2003; 63:8890-8898.
    • (2003) Cancer Res , vol.63 , pp. 8890-8898
    • Abdollahi, A.1    Lipson, K.E.2    Sckell, A.3
  • 64
    • 2442457534 scopus 로고    scopus 로고
    • Targeted radiotherapy of brain tumors
    • Zalutsky MR. Targeted radiotherapy of brain tumors. Br J Cancer 2004; 90:1469-1473. A recent review of targeted radiotherapy for brain tumors.
    • (2004) Br J Cancer , vol.90 , pp. 1469-1473
    • Zalutsky, M.R.1
  • 65
    • 0036498790 scopus 로고    scopus 로고
    • Phase II trial of murine 131 I-labelled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
    • Reardon DA, Akabani G, Coleman R, et al. Phase II trial of murine 131 I-labelled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol 2002; 20:1389-1397.
    • (2002) J Clin Oncol , vol.20 , pp. 1389-1397
    • Reardon, D.A.1    Akabani, G.2    Coleman, R.3
  • 66
    • 0038737151 scopus 로고    scopus 로고
    • Locoregional radioimmunotherapy in selected patients with malignant glioma: Experiences, side effects and survival times
    • Goetz C, Riva P, Poepperl G, et al. Locoregional radioimmunotherapy in selected patients with malignant glioma: experiences, side effects and survival times. J Neurooncol 2003; 62:321-328.
    • (2003) J Neurooncol , vol.62 , pp. 321-328
    • Goetz, C.1    Riva, P.2    Poepperl, G.3
  • 67
    • 1242293091 scopus 로고    scopus 로고
    • Radioimmunotherapy as a novel treatment regimen: 1251-labelled monoclonal antibody 425 in the treatment of high-grade brain gliomas
    • Quang TS, Brady LW. Radioimmunotherapy as a novel treatment regimen: 1251-labelled monoclonal antibody 425 in the treatment of high-grade brain gliomas. Int J Radiat Oncol Biol Phys 2004; 58:972-975.
    • (2004) Int J Radiat Oncol Biol Phys , vol.58 , pp. 972-975
    • Quang, T.S.1    Brady, L.W.2
  • 68
    • 0031801502 scopus 로고    scopus 로고
    • Iodine-131-labelled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: Phase I trial results
    • Bigner D, Brown M, Friedman AH, et al. Iodine-131-labelled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: phase I trial results. J Clin Oncol 1998; 16:2202-2212.
    • (1998) J Clin Oncol , vol.16 , pp. 2202-2212
    • Bigner, D.1    Brown, M.2    Friedman, A.H.3
  • 69
    • 23444437213 scopus 로고
    • Convection-enhanced delivery of macromolecules in the brain
    • Bobo, RH, Laske, DW, Akbasak A, et al. Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A 1994; 91:2076-2080.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 2076-2080
    • Bobo, R.H.1    Laske, D.W.2    Akbasak, A.3
  • 70
    • 0028144703 scopus 로고
    • High-flow microinfusion: Tissue penetration and pharmacodynamics
    • Morrison PF, Laske DW, Bobo H, et al. High-flow microinfusion: tissue penetration and pharmacodynamics. Am J Physiol 1994; 266:R292-R305.
    • (1994) Am J Physiol , vol.266
    • Morrison, P.F.1    Laske, D.W.2    Bobo, H.3
  • 71
    • 0028067301 scopus 로고
    • Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein
    • Puri RK, Leland P, Kreitman RJ, Pastan I. Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein. Int J Cancer 1994; 58:574-581.
    • (1994) Int J Cancer , vol.58 , pp. 574-581
    • Puri, R.K.1    Leland, P.2    Kreitman, R.J.3    Pastan, I.4
  • 72
    • 0344444830 scopus 로고    scopus 로고
    • Interleukin-4-Pseudomonas exotoxin chimeric fusion protein for malignant glioma therapy
    • Kawakami M, Kawakami K, Puri RK. Interleukin-4-Pseudomonas exotoxin chimeric fusion protein for malignant glioma therapy. J Neurooncol 2003; 65:15-25.
    • (2003) J Neurooncol , vol.65 , pp. 15-25
    • Kawakami, M.1    Kawakami, K.2    Puri, R.K.3
  • 73
    • 1542787924 scopus 로고    scopus 로고
    • Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma
    • Weber FW, Floeth F, Asher A, et al. Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma. Acta Neurochir Suppl 2003; 88:93-103.
    • (2003) Acta Neurochir Suppl , vol.88 , pp. 93-103
    • Weber, F.W.1    Floeth, F.2    Asher, A.3
  • 74
    • 1342287143 scopus 로고    scopus 로고
    • Long term survival in a patient with recurrent malignant glioma treated with intratumora/ infusion of an IL4-targeted toxin (NBI-3001)
    • Rainov NG, Heidecke V. Long term survival in a patient with recurrent malignant glioma treated with intratumora/ infusion of an IL4-targeted toxin (NBI-3001). J Neurooncol 2004; 66:197-201.
    • (2004) J Neurooncol , vol.66 , pp. 197-201
    • Rainov, N.G.1    Heidecke, V.2
  • 75
    • 3142515610 scopus 로고    scopus 로고
    • Peritumoral convection-enhanced delivery of IL-13-PE38QQR in patients with recurrent malignant glioma-phase I interim results
    • Abstract TA-15
    • Kunwar S, Prados M, Chang S, et al. Peritumoral convection-enhanced delivery of IL-13-PE38QQR in patients with recurrent malignant glioma-phase I interim results. Neuro-Oncology 2003; 5:350 [Abstract TA-15].
    • (2003) Neuro-Oncology , vol.5 , pp. 350
    • Kunwar, S.1    Prados, M.2    Chang, S.3
  • 76
    • 77952461038 scopus 로고    scopus 로고
    • Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: Presentation of interim findings from ongoing phase 1 studies
    • Kunwar S. Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies. Acta Neurochir Suppl 2003; 88:105-111.
    • (2003) Acta Neurochir Suppl , vol.88 , pp. 105-111
    • Kunwar, S.1
  • 77
    • 10744219583 scopus 로고    scopus 로고
    • Progress report of a phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors
    • Sampson JH, Akabani G, Archer GE, et al. Progress report of a phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol 2003; 65:27-35.
    • (2003) J Neurooncol , vol.65 , pp. 27-35
    • Sampson, J.H.1    Akabani, G.2    Archer, G.E.3
  • 78
    • 0037295311 scopus 로고    scopus 로고
    • DAB389EGF fusion protein therapy of refractory glioblastoma multiforme
    • Cohen KA, Liu T, Bissonette R, et al. DAB389EGF fusion protein therapy of refractory glioblastoma multiforme. Curr Pharm Biotechnol 2003; 4:39-49.
    • (2003) Curr Pharm Biotechnol , vol.4 , pp. 39-49
    • Cohen, K.A.1    Liu, T.2    Bissonette, R.3
  • 79
    • 3142597453 scopus 로고    scopus 로고
    • A phase I/II trail of intracavitary 131I-TM-601 in adult patients with recurrent high-grade-glioma
    • Abstract RA-19
    • Mamelak AN, Raubitschek A, Morgan R, et al. A phase I/II trail of intracavitary 131I-TM-601 in adult patients with recurrent high-grade-glioma. Neuro-Oncology 2003; 6:340 [Abstract RA-19].
    • (2003) Neuro-Oncology , vol.6 , pp. 340
    • Mamelak, A.N.1    Raubitschek, A.2    Morgan, R.3
  • 80
    • 0345307772 scopus 로고    scopus 로고
    • Targeting the over-expressed urokinase-type plasminogen activator receptor on glioblastoma multiforme
    • Rustamzadeh E, Li C, Doumbia S, Hall WA, Vallera DA. Targeting the over-expressed urokinase-type plasminogen activator receptor on glioblastoma multiforme. J Neurooncol 2003; 65:63-75.
    • (2003) J Neurooncol , vol.65 , pp. 63-75
    • Rustamzadeh, E.1    Li, C.2    Doumbia, S.3    Hall, W.A.4    Vallera, D.A.5
  • 81
    • 4444341835 scopus 로고    scopus 로고
    • SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility
    • Hjelmeland MD, Hjelmeland AB, Sathornsumetee S, et al. SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. Mol Cancer Ther 2004; 3:737-745.
    • (2004) Mol Cancer Ther , vol.3 , pp. 737-745
    • Hjelmeland, M.D.1    Hjelmeland, A.B.2    Sathornsumetee, S.3
  • 82
    • 25444491540 scopus 로고    scopus 로고
    • Specific therapy for high-grade glioma by convection-enhanced delivery of the TGF-β2 specific antisense oligonucleotide AP 12009
    • New Orleans, 4-8 June Abstract 1514
    • Bogdahn U, Hau P, Brawanski A, et al. Specific therapy for high-grade glioma by convection-enhanced delivery of the TGF-β2 specific antisense oligonucleotide AP 12009. In: Proceedings of the American Society of Clinical Oncology. New Orleans, 4-8 June 2004 [Abstract 1514].
    • (2004) Proceedings of the American Society of Clinical Oncology
    • Bogdahn, U.1    Hau, P.2    Brawanski, A.3
  • 83
    • 0041333077 scopus 로고    scopus 로고
    • Polilactofate microspheres for Paclitaxel delivery to central nervous system malignancies
    • Li KW, Dang W, Tyler BM, Troiano G, et al. Polilactofate microspheres for Paclitaxel delivery to central nervous system malignancies. Clin Cancer Res 2003; 9:3441-3447.
    • (2003) Clin Cancer Res , vol.9 , pp. 3441-3447
    • Li, K.W.1    Dang, W.2    Tyler, B.M.3    Troiano, G.4
  • 84
    • 1542682660 scopus 로고    scopus 로고
    • Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma
    • Menei P, Benoit JP. Implantable drug-releasing biodegradable microspheres for local treatment of brain glioma. Acta Neurochir Suppl 2003; 88:51-55.
    • (2003) Acta Neurochir Suppl , vol.88 , pp. 51-55
    • Menei, P.1    Benoit, J.P.2
  • 85
    • 0346093900 scopus 로고    scopus 로고
    • Stereotaxic implantation of 5-fluorouracil-releasing microspheres in malignant glioma
    • Menei P, Jadaud E, Faisant N, et al. Stereotaxic implantation of 5-fluorouracil-releasing microspheres in malignant glioma. Cancer 2004; 100:405-410.
    • (2004) Cancer , vol.100 , pp. 405-410
    • Menei, P.1    Jadaud, E.2    Faisant, N.3
  • 87
    • 0346252644 scopus 로고    scopus 로고
    • Novel chemotherapeutic agents for the treatment of glioblastoma multiforme
    • Jendrossek V; Belka C; Bamberg M. Novel chemotherapeutic agents for the treatment of glioblastoma multiforme. Exp Opin Invest Drugs 2003; 12:1899-1924.
    • (2003) Exp Opin Invest Drugs , vol.12 , pp. 1899-1924
    • Jendrossek, V.1    Belka, C.2    Bamberg, M.3
  • 88
    • 2442495498 scopus 로고    scopus 로고
    • Development of novel targeted therapies in the treatment of malignant glioma
    • Rich JN, Bigner DD. Development of novel targeted therapies in the treatment of malignant glioma. Nat Rev Drug Discov 2004; 3;430-446. A recent review of targeted molecular therapies for malignant gliomas.
    • (2004) Nat Rev Drug Discov , vol.3 , pp. 430-446
    • Rich, J.N.1    Bigner, D.D.2
  • 89
    • 0027469702 scopus 로고
    • Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen
    • Couldwell WT, Weiss MH, DeGiorgio CM, et al. Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen. Neurosurgery 1993; 32:485-489.
    • (1993) Neurosurgery , vol.32 , pp. 485-489
    • Couldwell, W.T.1    Weiss, M.H.2    Degiorgio, C.M.3
  • 90
    • 0033036888 scopus 로고    scopus 로고
    • Salvage chemotherapy with tamoxifen for recurrent anaplastic astrocytomas
    • Chamberlain MC, Kormanik PA. Salvage chemotherapy with tamoxifen for recurrent anaplastic astrocytomas. Arch Neurol 1999; 56:703-708.
    • (1999) Arch Neurol , vol.56 , pp. 703-708
    • Chamberlain, M.C.1    Kormanik, P.A.2
  • 91
    • 0037235850 scopus 로고    scopus 로고
    • Propylthiouracil-induced chemical hypothyroidism with high-dose tamoxifen prolongs survival in recurrent high grade glioma: A phase I/II study
    • Hercbergs AA, Goyal LK, Suh JH, et al. Propylthiouracil-induced chemical hypothyroidism with high-dose tamoxifen prolongs survival in recurrent high grade glioma: a phase I/II study. Anticancer Res 2003; 23:617-626.
    • (2003) Anticancer Res , vol.23 , pp. 617-626
    • Hercbergs, A.A.1    Goyal, L.K.2    Suh, J.H.3
  • 92
    • 4344688936 scopus 로고    scopus 로고
    • Retinoic acid in the treatment of recurrent glioblastoma multiforme
    • See S-J, Levin VA, Yung WKA, et al. 13-cis-Retinoic acid in the treatment of recurrent glioblastoma multiforme. Neuro-Oncology 2004; 6:253-258.
    • (2004) Neuro-Oncology , vol.6 , pp. 253-258
    • See, S.-J.1    Levin, V.A.2    Yung, W.K.A.3
  • 93
    • 2942750165 scopus 로고    scopus 로고
    • Maintenance therapy with 13-cis retinoid acid in high-grade glioma at complete response after first-line multimodal therapy - A phase-II study
    • Wismeth C, Hau P, Fabel K, et al. Maintenance therapy with 13-cis retinoid acid in high-grade glioma at complete response after first-line multimodal therapy - a phase-II study. J Neurooncol 2004; 68:79-86.
    • (2004) J Neurooncol , vol.68 , pp. 79-86
    • Wismeth, C.1    Hau, P.2    Fabel, K.3
  • 94
    • 14944353655 scopus 로고    scopus 로고
    • A phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: A North American Brain Tumor Consortium (NABTC) Study
    • in press
    • Puduvalli VK, Yung WKA, Hess KR, et al. A phase II study of fenretinide (NSC 374551) in adults with recurrent malignant gliomas: a North American Brain Tumor Consortium (NABTC) Study. J Clin Oncol 2004; in press.
    • (2004) J Clin Oncol
    • Puduvalli, V.K.1    Yung, W.K.A.2    Hess, K.R.3
  • 96
    • 2442505874 scopus 로고    scopus 로고
    • Treatment of glioblastoma with intravenous taurolidine. First clinical experience
    • Stendel R, Picht T, Schilling A. Treatment of glioblastoma with intravenous taurolidine. First clinical experience. Anticancer Res 2004; 24:1143-1147.
    • (2004) Anticancer Res , vol.24 , pp. 1143-1147
    • Stendel, R.1    Picht, T.2    Schilling, A.3
  • 97
    • 0035398022 scopus 로고    scopus 로고
    • New Approaches to Brain Tumor Therapy CNS Consortium. Toxicity, efficacy, and pharmacology of suramin in adults with recurrent high-grade gliomas
    • Grossman SA, Phuphanich S, Lesser G, et al. New Approaches to Brain Tumor Therapy CNS Consortium. Toxicity, efficacy, and pharmacology of suramin in adults with recurrent high-grade gliomas. J Clin Oncol 2001; 19:3260-3266.
    • (2001) J Clin Oncol , vol.19 , pp. 3260-3266
    • Grossman, S.A.1    Phuphanich, S.2    Lesser, G.3
  • 98
    • 0942277090 scopus 로고    scopus 로고
    • NABTT CNS Consortium study. Suramin and radiotherapy in newly diagnosed glioblastoma: Phase 2 NABTT CNS Consortium study
    • Laterra JJ, Grossman SA, Carson KA, et al., NABTT CNS Consortium study. Suramin and radiotherapy in newly diagnosed glioblastoma: phase 2 NABTT CNS Consortium study. Neuro-oncol 2004; 6:15-20.
    • (2004) Neuro-oncol , vol.6 , pp. 15-20
    • Laterra, J.J.1    Grossman, S.A.2    Carson, K.A.3
  • 99
    • 4143071413 scopus 로고    scopus 로고
    • In vitro and in vivo activity of the nuclear factor-{kappa}B inhibitor sulfasalazine in human glioblastomas
    • Robe PA, Bentires-Alj M, Bonif M, et al. In vitro and in vivo activity of the nuclear factor-{kappa}B inhibitor sulfasalazine in human glioblastomas. Clin Cancer Res 2004; 10:5595-5603.
    • (2004) Clin Cancer Res , vol.10 , pp. 5595-5603
    • Robe, P.A.1    Bentires-Alj, M.2    Bonif, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.