Hypoxic inhibition of 3-methylcholanthrene-induced CYP1A1 expression is independent of HIF-1alpha

Toxicology Letters

Volumn 155, Issue 1, 2005, Pages 151-159

  Allen, Jared W ^a   Johnson, Randall S ^a   Bhatia, Sangeeta N ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Aryl hydrocarbon receptor (AhR); Aryl hydrocarbon receptor nuclear translocator (ARNT); Cytochrome P450 1A1 (CYP1A1); Hypoxia; Hypoxia inducible factor (HIF); Primary hepatocytes

Indexed keywords

3 METHYLCHOLANTHRENE; AROMATIC HYDROCARBON; CYTOCHROME P450 1A1; GLUCOSE TRANSPORTER 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LIGAND; OXYGEN; PHOSPHOGLYCERATE KINASE; VASCULOTROPIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE TARGETING; HYPOXIA; INHIBITION KINETICS; LIVER CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

ADENOVIRIDAE; ANIMALS; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR; CELL HYPOXIA; CELL SEPARATION; CELLS, CULTURED; CYTOCHROME P-450 CYP1A1; DNA-BINDING PROTEINS; ENZYME INHIBITORS; GLUCOSE TRANSPORTER TYPE 1; HEPATOCYTES; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MALE; METHYLCHOLANTHRENE; MICE; MICE, INBRED C57BL; MONOSACCHARIDE TRANSPORT PROTEINS; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 10044250078     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2004.09.006     Document Type: Article

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