Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use

Biochemistry

Volumn 43, Issue 4, 2004, Pages 879-889

  Kavanagh, Kathryn L ^a   Elling, Robert A ^a   Wilson, David K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYMES; FLUORESCENCE; ISOMERIZATION; PH EFFECTS; QUENCHING;

GLYCOLYSIS; TOXOPLASMIC ENCEPHALITIS;

BIOCHEMISTRY;

3 ACETYLPYRIDINE ADENINE DINUCLEOTIDE; DINUCLEOTIDE; ENZYME INHIBITOR; LACTATE DEHYDROGENASE 1; LACTATE DEHYDROGENASE INHIBITOR; LACTATE DEHYDROGENASE ISOENZYME; LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE; SERINE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; DEVELOPMENTAL STAGE; DRUG DESIGN; ENCEPHALITIS; ENERGY RESOURCE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME ISOLATION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; FLUORESCENCE; GLYCOLYSIS; IMMUNE DEFICIENCY; ISOMERIZATION; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; PARASITE DEVELOPMENT; PH; PRIORITY JOURNAL; PROTEIN TARGETING; TOXOPLASMA GONDII;

PROTOZOA; TOXOPLASMA GONDII;

EID: 0942268914     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035108g     Document Type: Article

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