Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum

Molecular and Biochemical Parasitology

Volumn 90, Issue 1, 1997, Pages 235-246

  Gomez, Manuel S ^a   Piper, Robert C ^b   Hunsaker, Lucy A ^a   Royer, Robert E ^a   Deck, Lorraine M ^c   Makler, Michael T ^d   Vander Jagt, David L ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OREGON   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cofactor specificity; Inhibitors; Lactate dehydrogenase; Plasmodium falciparum; Substrate specificity

Indexed keywords

ENZYME INHIBITOR; LACTATE DEHYDROGENASE; PYRUVIC ACID;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; DISSOCIATION CONSTANT; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; ENZYME INHIBITORS; GOSSYPOL; HUMANS; ISOELECTRIC POINT; KINETICS; L-LACTATE DEHYDROGENASE; LACTIC ACID; MOLECULAR SEQUENCE DATA; NAD; PLASMODIUM FALCIPARUM; PYRUVIC ACID; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

FELIS CATUS; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0031453699     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00140-0     Document Type: Article

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