A general method for relieving substrate inhibition in lactate dehydrogenases

Protein Engineering

Volumn 12, Issue 6, 1999, Pages 491-496

  Hewitt, C O ^b   Eszes, C M ^b   Sessions, R B ^b   Moreton, K M ^b   Dafforn, T R ^a   Takei, J ^b   Dempsey, C E ^b   Clarke, A R ^b   Holbrook, J J ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b SCHOOL OF MEDICAL SCIENCES   (United Kingdom)

Author keywords

Lactate dehydrogenase; Mutagenesis; Protein engineering; Substrate inhibition

Indexed keywords

LACTATE DEHYDROGENASE; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVIC ACID;

ARTICLE; CONTROLLED STUDY; COVALENT BOND; ENANTIOMER; ENZYME BINDING; ENZYME INHIBITION; GENETIC ENGINEERING; MICHAELIS CONSTANT; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL;

EID: 0033001020     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/12.6.491     Document Type: Article

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