Structural basis of substrate specificity in malate dehydrogenases: Crystal structure of a ternary complex of porcine cytoplasmic malate dehydrogenase, α-ketomalonate and tetrahydoNAD

Journal of Molecular Biology

Volumn 285, Issue 2, 1999, Pages 703-712

  Chapman, A D M ^a   Cortes A ^b   Dafforn, T R ^c   Clarke, A R ^a   Brady, R L ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Active site loop; Malate dehydrogenase; Protein crystallography; Reaction mechanism; Ternary complex

Indexed keywords

ARGININE; CYTOPLASM PROTEIN; MALATE DEHYDROGENASE; MALONIC ACID DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE DERIVATIVE;

ARTICLE; COENZYME; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL;

ESCHERICHIA COLI; PROKARYOTA; SUIDAE; THERMUS THERMOPHILUS;

EID: 0033555285     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2357     Document Type: Article

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