Comprehensive genomics linking between neural development and cancer: Neuroblastoma as a model

Cancer Letters

Volumn 204, Issue 2, 2004, Pages 213-224

  Nakagawara, Akira ^a   Ohira, Miki ^a  

^a CHIBA CANCER CENTER   (Japan)

Author keywords

Comprehensive genomics; Neural development; Neuroblastoma cDNA project

Indexed keywords

APOPTOSIS; CANCER; CANCER CELL; CELL MATURATION; GENETIC LINKAGE; HUMAN; INTESTINE INNERVATION; MOLECULAR BIOLOGY; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL CREST; NEUROBLASTOMA; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENSORY NERVE CELL; SOLID TUMOR; STEM CELL; SYMPATHETIC NERVE CELL;

EID: 0842330655     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(03)00457-9     Document Type: Article

References (70)

1. Bolande R.P. The neurocristopathies: a unifying concept of disease arising in neural crest maldevelopment. Human Pathol. 5:1974;409-429.
2. Brodeur G.M. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer. 3:2003;203-216.
3. Nakagawara A. Molecular basis of spontaneous regression of neuroblastoma: role of neurotrophic signals and genetic abnormalities. Human Cell. 11:1998;115-124.
4. Beckwith J.B., Perrin E.V. In situ neuroblastomas: a contribution to the natural history of neural crest tumors. Am. J. Pathol. 43:1963;1089-1101.
5. Sawada T., Hirayama M., Nakata T., Takeda T., Takasugi N., Mori T., Maeda K., Koide R., Hanawa Y., Tsunoda A., Shimizu K., Nagahara N., Yamamoto K. Mass screening for neuroblastoma in infants in Japan. Interim report of a mass screening study group. Lancet. 2:1984;271-273.
6. Bessho F. Where should neuroblastoma mass screening go? Lancet. 348:1996;1682-1687.
7. Woods W.G., Gao R.N., Shuster J.J., Robison L.L., Bernstein M., Weitzman S., Bunin G., Levy I., Brossard J., Dougherty G., Tuchman M., Lemieux B. Screening of infants and mortality due to neuroblastoma. N. Engl. J. Med. 346:2002;1041-1046.
8. Nakagawara A., Arima-Nakagawara M., Scavarda N.J., Azar C.G., Cantor A.B., Brodeur G.M. Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N. Engl. J. Med. 328:1993;847-854.
9. Nakagawara A. The NGF Story and Neuroblastoma. Med. Pediatr. Oncol. 31:1998;113-115.
10. Zimmerman K.A., Yancopoulos G.D., Collum R.G., Smith R.K., Kohl N.E., Denis K.A., Nau M.M., Witte O.N., Toran-Allerand D., Gee C.E., Minna J.D., Alt F.D. Differential expression of myc family genes during murine development. Nature. 319:1986;780-783.
11. Hallbook F., Backstrom A., Kullander K., Kylberg A., Williams R., Ebendal T. Neurotrophins and their receptors in chicken neuronal development. Int. J. Dev. Biol. 39:1995;855-868.
12. Shah N.M., Anderson D.J. Integration of multiple instructive cues by neural crest stem cells reveals cell-intrinsic biases in relative growth factor responsiveness. Proc. Natl Acad. Sci. USA. 94:1997;11369-11374.
13. Shah N.M., Groves A.K., Anderson D.J. Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members. Cell. 85:1996;331-343.
14. Huber K., Bruhl B., Guillemot F., Olson E.N., Ernsberger U., Unsicker K. Development of chromaffin cells depends on MASH1 function. Development. 129:2002;4729-4738.
15. Anderson D.J. Molecular control of cell fate in the neural crest: the sympathoadrenal lineage. Annu. Rev. Neurosci. 16:1993;129-158.
16. Stanke M., Junghans D., Geissen M., Goridis C., Ernsberger U., Rohrer H. The Phox2 homeodomain proteins are sufficient to promote the development of sympathetic neurons. Development. 129:1999;4087-4094.
17. Patzke H., Reissmann E., Stanke M., Bixby J.L., Ernsberger U. BMP growth factors and Phox2 transcription factors can induce synaptotagmin I and neurexin I during sympathetic neuron development. Mech. Dev. 108:2001;149-159.
18. Pattyn A., Morin X., Cremer H., Goridis C., Brunet J.F. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives. Nature. 399:1999;366-370.
19. Nakagawara A. Trk receptor tyrosine kinases: a bridge between cancer and neural development. Cancer Lett. 169:2001;107-114.
20. Okubo K., Hori N., Matoba R., Niiyama T., Fukushima A., Kojima Y., Matsubara K. Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression. Nat. Genet. 2:1992;173-179.
21. Ohira M., Shishikura T., Kawamoto T., Inuzuka H., Morohashi A., Takayasu H., Kageyama H., Takada N., Takahashi M., Sakiyama S., Suzuki Y., Sugano S., Kuma H., Nozawa I., Nakagawara A. Hunting the subset-specific genes of neuroblastoma: expression profiling and differential screening of the full-length-enriched oligo-capping cDNA libraries. Med. Pediatr. Oncol. 35:2000;547-549.
22. Ohira M., Morohashi A., Inuzuka H., Shishikura T., Kawamoto T., Kageyama H., Nakamura Y., Isogai E., Takayasu H., Sakiyama S., Suzuki Y., Sugano S., Goto T., Sato S., Nakagawara A. Expression profiling and characterization of 4,200 genes cloned from primary neuroblastomas: identification of 305 genes differentially expressed between favorable and unfavorable subsets. Oncogene. 22:2003;5525-5536.
23. White P.M., Morrison S.J., Orimoto K., Kubu C.J., Verdi J.M., Anderson D.J. Neural crest stem cells undergo cell-intrinsic developmental changes in sensitivity to instructive differentiation signals. Neuron. 29:2001;57-71.
24. Van Limpt V.A., Chan A.J., Van Sluis P.G., Caron H.N., Van Noesel C.J., Versteeg R. High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type. Int. J. Cancer. 105:2003;61-69.
25. Jogi A., Ora I., Nilsson H., Lindeheim A., Makino Y., Poellinger L., Axelson H., Pahlman S. Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype. Proc. Natl Acad. Sci. USA. 99:2002;7021-7026.
26. Soderholm H., Ortoft E., Johansson I., Ljungberg J., Larsson C., Axelson H., Pahlman S. Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells. Biochem. Biophys. Res. Commun. 256:1999;557-563.
27. Ichimiya S., Nimura Y., Seki N., Ozaki T., Nagase T., Nakagawara A. Downregulation of hASH1 is associated with the retinoic acid-induced differentiation of human neuroblastoma cell lines. Med. Pediatr. Oncol. 36:2001;132-134.
28. Anderson D.J., Groves A., Lo L., Ma Q., Rao M., Shah N.M., Sommer L. Cell lineage determination and the control of neuronal identity in the neural crest. Cold Spring Harb. Symp. Quant. Biol. 62:1997;493-504.
29. Guillemot F., Lo L.C., Johnson J.E., Auerbach A., Anderson D.J., Joyner A.L. Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell. 75:1993;463-476.
30. Yoshida I., Koide S., Hasegawa S.I., Nakagawara A., Tsuji A., Matsuda Y. Proprotein convertase PACE4 is down-regulated by the basic helix-loop-helix transcription factor hASH-1 and MASH-1. Biochem. J. 360:2001;683-689.
31. Grynfeld A., Pahlman S., Axelson H. Induced neuroblastoma cell differentiation, associated with transient HES-1 activity and reduced HASH-1 expression, is inhibited by Notch1. Int. J. Cancer. 88:2000;401-410.
32. Lasorella A., Noseda M., Beyna M., Iavarone A. Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature. 407:2000;592-598.
33. Brodeur G.M. Molecular basis for heterogeneity in human neuroblastomas. Eur. J. Cancer. 31:1995;505-510.
34. Westermann F., Schwab M. Genetic parameters of neuroblastomas. Cancer Lett. 184:2002;127-147.
35. Hirsch M.R., Tiveron M.C., Guillemot F., Brunet J.F., Goridis C. Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 125:1998;599-608.
36. Wakamatsu Y., Watanabe Y., Nakamura H., Kondoh H. Regulation of the neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation. Development. 124:1997;1953-1962.
37. Yin Z., Haynie J., Yang X., Han B., Kiatchoosakun S., Restivo J., Yuan S., Prabhakar N.R., Herrup K., Conlon R.A., Hoit B.D., Watanabe M., Yang Y.C. The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc. Natl Acad. Sci. USA. 99:2002;10488-10493.
38. Aloyz R.S., Bamji S.X., Pozniak C.D., Toma J.G., Atwal J., Kaplan D.R., Miller F.D. p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. J. Cell Biol. 143:1998;1691-1703.
39. Kaghad M., Bonnet H., Yang A., Creancier L., Biscan J.C., Valent A., Minty A., Chalon P., Lelias J.M., Dumont X., Ferrara P., McKeon F., Caput D. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell. 90:1997;809-819.
40. Schwab M., Varmus H.E., Bishop J.M., Grzeschik K.H., Naylor S.L., Sakaguchi A.Y., Brodeur G., Trent J. Chromosome localization in normal human cells and neuroblastomas of a gene related to c-myc. Nature. 308:1984;288-291.
41. Brodeur G.M., Seeger R.C., Schwab M., Varmus H.E., Bishop J.M. Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science. 224:1984;1121-1124.
42. Nakagawara A., Arima M., Azar C.G., Scavarda N.J., Brodeur G.M. Inverse relationship between trk expression and N-myc amplification in human neuroblastomas. Cancer Res. 52:1992;1364-1368.
43. Suzuki T., Bogenmann E., Shimada H., Stram D., Seeger R.C. Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas. J. Natl Cancer Inst. 85:1993;377-384.
44. Kogner P., Barbany G., Dominici C., Castello M.A., Raschella G., Persson H. Coexpression of messenger RNA for TRK protooncogene and low affinity nerve growth factor receptor in neuroblastoma with favorable prognosis. Cancer Res. 53:1993;2044-2050.
45. Nakagawara A., Azar C.G., Scavarda N.J., Brodeur G.M. Expression and function of TRK-B and BDNF in human neuroblastomas. Mol. Cell Biol. 14:1994;759-767.
46. TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells. Cancer Res. 55:1995;1798-1806.
47. Pozniak C.D., Radinovic S., Yang A., McKeon F., Kaplan D.R., Miller F.D. An anti-apoptotic role for the p53 family member, p73, during developmental neuron death. Science. 289:2000;304-306.
48. Yang A., Walker N., Bronson R., Kaghad M., Oosterwegel M., Bonnin J., Vagner C., Bonnet H., Dikkes P., Sharpe A., McKeon F., Caput D. p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature. 404:2000;99-103.
49. Nakagawa T., Takahashi M., Ozaki T., Watanabe K., Todo S., Mizuguchi H., Hayakawa T., Nakagawara A. Autoinhibitory regulation of p73 by Delta Np73 to modulate cell survival and death through a p73-specific target element within the Delta Np73 promoter. Mol. Cell Biol. 22:2002;2575-2585.
50. Grob T.J., Novak U., Maisse C., Barcaroli D., Luthi A.U., Pirnia F., Hugli B., Graber H.U., De Laurenzi V., Fey M.F., Melino G., Tobler A. Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53. Cell Death Differ. 8:2001;1213-1223.
51. Watanabe K., Ozaki T., Nakagawa T., Miyazaki K., Takahashi M., Hosoda M., Hayashi S., Todo S., Nakagawara A. Physical interaction of p73 with c-Myc and MM1, a c-Myc-binding protein, and modulation of the p73 function. J. Biol. Chem. 277:2002;15113-15123.
52. Casciano I., Mazzocco K., Boni L., Pagnan G., Banelli B., Allemanni G., Ponzoni M., Tonini G.P., Romani M. Expression of DeltaNp73 is a molecular marker for adverse outcome in neuroblastoma patients. Cell Death Differ. 9:2002;246-251.
53. van Limpt V., Chan A., Caron H., Sluis P.V., Boon K., Hermus M.C., Versteeg R. SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene. Med. Pediatr. Oncol. 35:2000;554-558.
54. Spieker N., van Sluis P., Beitsma M., Boon K., van Schaik B.D., van Kampen A.H., Caron H., Versteeg R. The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32. Genomics. 71:2001;214-221.
55. Nakagawara A., Ikeda K., Higashi K., Sasazuki T. Inverse correlation between N-myc amplification and catecholamine metabolism in children with advanced neuroblastoma. Surgery. 107:1990;43-49.
56. Easton R.M., Deckwerth T.L., Parsadanian A.S., Johnson E.M. Jr. Analysis of the mechanism of loss of trophic factor dependence associated with neuronal maturation: a phenotype indistinguishable from Bax deletion. J. Neurosci. 17:1997;9656-9666.
57. Albertson D.G., Ylstra B., Segraves R., Collins C., Dairkee S.H., Kowbel D., Kuo W.L., Gray J.W., Pinkel D. Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nat. Genet. 25:2000;144-146.
58. Imai Y., Soda M., Hatakeyama S., Akagi T., Hashikawa T., Nakayama K.I., Takahashi R., is C.H.I.P. associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol. Cell. 10:2002;55-67.
59. Chen M.S., Huber A.B., van der Haar M.E., Frank M., Schnell L., Spillmann A.A., Christ F., Schwab M.E. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature. 403:2000;434-439.
60. Crispino J.D., Lodish M.B., Thurberg B.L., Litovsky S.H., Collins T., Molkentin J.D., Orkin S.H. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev. 15:2001;839-844.
61. Opdam F.J., Kamps G., Croes H., van Bokhoven H., Ginsel L.A., Fransen J.A. Expression of Rab small GTPases in epithelial Caco-2 cells: Rab21 is an apically located GTP-binding protein in polarised intestinal epithelial cells. Eur. J. Cell Biol. 79:2000;308-316.
62. Tateno M., Fukunishi Y., Komatsu S., Okazaki Y., Kawai J., Shibata K., Itoh M., Muramatsu M., Held W.A., Hayashizaki Y. Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice. Cancer Res. 61:2001;1144-1153.
63. Margolis R.L., Stine O.C., Ward C.M., Franz M.L., Rosenblatt A., Callahan C., Sherr M., Ross C.A., Potter N.T. Unstable expansion of the CAG trinucleotide repeat in MAB21L1: report of a second pedigree and effect on protein expression. J. Med. Genet. 36:1999;62-64.
64. Wada M., Nakanishi H., Satoh A., Hirano H., Obaishi H., Matsuura Y., Takai Y. Isolation and characterization of a GDP/GTP exchange protein specific for the Rab3 subfamily small G proteins. J. Biol. Chem. 272:1997;3875-3878.
65. Missler M., Hammer R.E., Sudhof T.C. Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit. J. Biol. Chem. 273:1998;34716-34723.
66. Wang Y., Sugita S., Sudhof T.C. The RIM/NIM family of neuronal C2 domain proteins. Interactions with Rab3 and a new class of Src homology 3 domain proteins. J. Biol. Chem. 275:2000;20033-20044.
67. Poliak S., Gollan L., Martinez R., Custer A., Einheber S., Salzer J.L., Trimmer J.S., Shrager P., Peles E. Caspr2, a new member of the neurexin superfamily, is localized at the juxtaparanodes of myelinated axons and associates with K+ channels. Neuron. 24:1999;1037-1047.
68. Valdenaire O., Richards J.G., Faull R.L., Schweizer X.C.E. new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS. Brain Res. Mol. Brain Res. 64:1999;211-221.
69. Lin P.T., Gleeson J.G., Corbo J.C., Flanagan L., Walsh C.A. DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization. J. Neurosci. 20:2000;9152-9161.
70. Wang X., Kibschull M., Laue M.M., Lichte B., Petrasch-Parwez E., Kilimann M.W. Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin. J. Cell Biol. 147:1999;151-162.