Killing efficacy of a new silicon phthalocyanine in human melanoma cells treated with photodynamic therapy by early activation of mitochondrion-mediated apoptosis

Experimental Dermatology

Volumn 13, Issue 1, 2004, Pages 33-44

  Barge, J́rôme ^a   Decréau, Richard ^a   Julliard, Michel ^a   Hubaud, Jean Claude ^b   Sabatier, Anne Sophie ^a,b   Grob, Jean Jacques ^a   Verrando, Patrick ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b Devmt Pour les Technol Avancees   (France)

Author keywords

Apoptosis; Melanoma cells; Mitochondrion; PDT; Phthalocyanine

Indexed keywords

BIS(CHOLESTERYLOXYDIPHENYLSILOXY)SILICON PHTHALOCYANINE; BIS(DIHYDROXY)SILICON PHTHALOCYANINE; BIS(TRI N HEXYLSILOXY)SILICON PHTHALOCYANINE; CASPASE 9; CHLOROALUMINUM PHTHALOCYANINE; CYTOCHROME C; DICHOLESTERYLOXYSILICON PHTHALOCYANINE; DIEPIGLOBULOXYSILICON PHTHALOCYANINE; DIOCTYLOXYSILICON PHTHALOCYANINE; ONCOPROTEIN; PHOTOSENSITIZING AGENT; PROTEIN BCL 2; SILICON PHTHALOCYANINE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASSAY; CELL DAMAGE; CELL DEATH; CELL KILLING; CELL KINETICS; CELL PERMEABILIZATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; LD 50; MELANOMA; MELANOMA CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PHOTODYNAMIC THERAPY; PHOTOOXIDATION; PROTEIN SECRETION;

APOPTOSIS; CASPASE 9; CASPASES; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; HUMANS; INDOLES; MELANOMA; MITOCHONDRIA; ORGANOSILICON COMPOUNDS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0842286516     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2004.00147.x     Document Type: Article

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