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2
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0013255608
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A cluster of cases of severe acute respiratory syndrome in Hong Kong
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Tsang KW, Ho PL, Ooi GC, et al.: A cluster of cases of severe acute respiratory syndrome in Hong Kong. N Engl J Med 2003, 348:1977-1985. One of two papers published simultaneously providing the first description of SARS. This paper from Hong Kong reviews 10 cases of SARS.
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N Engl J Med
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Tsang, K.W.1
Ho, P.L.2
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0013165966
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Identification of severe acute respiratory syndrome in Canada
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Poutanen SM, Low DE, Henry B, et al.: Identification of severe acute respiratory syndrome in Canada. N Engl J Med 2003, 348:1995-2005. This is one of two initial publications describing SARS, reviewing the initial 10 cases from Toronto, and suggesting an etiologic role of the coronavirus.
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N Engl J Med
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Poutanen, S.M.1
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A major outbreak of severe acute respiratory syndrome in Hong Kong
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Lee N, Hui D, Wu A, et al.: A major outbreak of severe acute respiratory syndrome in Hong Kong. N Engl J Med 2003, 348:1986-1994. A detailed description of the clinical characteristics of 138 patients with SARS from Hong Kong.
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N Engl J Med
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Lee, N.1
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1 November 2002-7 August 2003
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World Health Organization: Summary table of SARS cases by country, 1 November 2002-7 August 2003. http://www.who.int/csr/sars/ country/2003_08_15/en/ . Accessed September 4th, 2003.
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Summary Table of SARS Cases by Country
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A novel coronavirus associated with severe acute respiratory syndrome
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Ksiazek TG, Erdman D, Goldsmith CS, et al.: A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med 2003, 348:1953-1966. This is one of two papers identifying a novel coronavirus from clinical specimens of patients with SARS and demonstrating a lack of antibodies in a sample of control subjects from the United States.
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N Engl J Med
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Ksiazek, T.G.1
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Goldsmith, C.S.3
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Identification of a novel coronavirus in patients with severe acute respiratory syndrome
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Drosten C, Gunther S, Preiser W, et al.: Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N Engl J Med 2003, 348:1967-1976. This is one of two initial publications identifying a novel coronavirus from clinical specimens of SARS patients
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N Engl J Med
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Drosten, C.1
Gunther, S.2
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Coronavirus as a possible cause of severe acute respiratory syndrome
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Peiris JS, Lai ST, Poon LL, et al.: Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet 2003, 361:1319-1325. This study analyzed 50 patients with a clinical diagnosis of SARS and demonstrated evidence of infection with a novel coronavirus in clinical specimens of 45 patients.
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Peiris, J.S.1
Lai, S.T.2
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Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome
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Kuiken T, Fouchier RA, Schutten M, et al.: Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome. Lancet 2003, 362:263-270. An important study confirming SARS-CoV as the etiologic agent of SARS, by demonstrating the virus in clinical specimens and producing a SARS-syndrome in animals by inoculation of the virus.
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Lancet
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Kuiken, T.1
Fouchier, R.A.2
Schutten, M.3
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10
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The genome sequence of the SARS-associated coronavirus
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Marra MA, Jones SJ, Astell CR, et al.: The genome sequence of the SARS-associated coronavirus. Science 2003, 300:1399-1404. This is the first description of the full gene sequence of the newly identified SARS-CoV, demonstrating that this virus does not resemble previously described coronaviruses.
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Science
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Marra, M.A.1
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Severe acute respiratory syndrome: Singapore, 2003
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Severe acute respiratory syndrome: Singapore, 2003. MMWR Morb Mortal Wkly Rep 2003, 52:405-411
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MMWR Morb Mortal Wkly Rep
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Riley S, Fraser C, Donnelly CA, et al.: Transmission dynamics of the etiological agent. Science 2003, 300:1961-1966. This analysis of the first 10 weeks of the SARS outbreak in Hong Kong identifies the SARS-CoV as being moderately transmissible, with occasional "super-spreaders".
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Science
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Riley, S.1
Fraser, C.2
Donnelly, C.A.3
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13
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Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: A prospective study
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Peiris JSM, Chu CM, Cheng VCC, et al.: Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet 2003, 361:1767-1772. A very valuable study from Hong Kong that prospectively followed 75 patients for 3 weeks, describing the pattern of viral shedding, usefulness of viral testing, and prognostic factors for poor outcome.
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Lancet
, vol.361
, pp. 1767-1772
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Peiris, J.S.M.1
Chu, C.M.2
Cheng, V.C.C.3
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Cluster of severe acute respiratory syndrome cases among protected healthcare workers: Toronto, Canada, April 2003
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Cluster of severe acute respiratory syndrome cases among protected healthcare workers: Toronto, Canada, April 2003. MMWR Morb Mortal Wkly Rep 2003, 52:433-436.
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MMWR Morb Mortal Wkly Rep
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Evaluation of WHO criteria for identifying patients with severe acute respiratory syndrome out of hospital: Prospective observational study
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Rainer TH, Cameron PA, Smit D, et al.: Evaluation of WHO criteria for identifying patients with severe acute respiratory syndrome out of hospital: prospective observational study. BMJ 2003, 326:1354-1358.
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BMJ
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Rainer, T.H.1
Cameron, P.A.2
Smit, D.3
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18
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0842321741
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World Health Organization: Use of laboratory tests for SARS diagnosis. Available at: http://www.who.int/csr/sars/labmethods/en/ Accessed September 4th, 2003.
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Use of Laboratory Tests for SARS Diagnosis
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19
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0037976821
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Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area
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Booth CM, Matukas LM, Tomlinson GA, et al.: Clinical features and short-term outcomes of 144 patients with SARS in the greater Toronto area. JAMA 2003, 289:2801-2809. The Toronto group provide a detailed review of 144 patients with SARS, in terms of the clinical features, diagnostic criteria, disease course, management, and factors affecting outcome.
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JAMA
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Booth, C.M.1
Matukas, L.M.2
Tomlinson, G.A.3
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20
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Severe acute respiratory syndrome: Clinical outcome and prognostic correlates
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Tsui PT, Kwok ML, Yuen H, Lai ST: Severe acute respiratory syndrome: clinical outcome and prognostic correlates. Emerging Infect Dis 2003, 9:1064-1069. This large retrospective analysis of 323 patients from Hong Kong characterizes the clinical course and identifies pretreatment prognostic factors.
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Emerging Infect Dis
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Tsui, P.T.1
Kwok, M.L.2
Yuen, H.3
Lai, S.T.4
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Critically ill patients with severe acute respiratory syndrome
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Fowler RA, Lapinsky SE, Hallett D, et al.: Critically ill patients with severe acute respiratory syndrome. JAMA 2003, 290:367-373. The Toronto group characterize the clinical features and course of 39 critically ill patients with SARS and the effect of the outbreak on critical resources in the city.
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JAMA
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Fowler, R.A.1
Lapinsky, S.E.2
Hallett, D.3
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Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome
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Lew TWK, Kwek TK, Tai D, et al.: Acute respiratory distress syndrome in critically ill patients with severe acute respiratory syndrome. JAMA 2003, 290:374-380. This study from Singapore describes the ICU course of 46 critically ill patients with SARS, including ventilatory parameters, complications, and outcome.
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JAMA
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Lew, T.W.K.1
Kwek, T.K.2
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Severe acute respiratory syndrome: Radiographic appearances and pattern of progression in 138 patients
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Wong KT, Antonio GE, Hui DS, et al.: Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients. Radiology 2003, 228:401-406. This paper describes the chest radiographic appearance and evolution in 138 patients with SARS.
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Radiology
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Wong, K.T.1
Antonio, G.E.2
Hui, D.S.3
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Severe acute respiratory syndrome: Radiographic review of 40 probable cases in Toronto, Canada
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Grinblat L, Shulman H, Glickman A, et al.: Severe acute respiratory syndrome: radiographic review of 40 probable cases in Toronto, Canada. Radiology 2003, 228:802-809. This study evaluated the chest radiographic progression of 40 patients with SARS.
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Radiology
, vol.228
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Grinblat, L.1
Shulman, H.2
Glickman, A.3
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Thin-section CT of severe acute respiratory syndrome: Evaluation of 73 patients exposed to or with the disease
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Wong KT, Antonio GE, Hui DS, et al.: Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the disease. Radiology 2003, 228:395-400. The first detailed description of the computed tomographic appearance of SARS, based on findings in 74 patients.
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Radiology
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Wong, K.T.1
Antonio, G.E.2
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Development of a standard treatment protocol for severe acute respiratory syndrome
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So LK, Lau ACW, Yam LYC, et al.: Development of a standard treatment protocol for severe acute respiratory syndrome. Lancet 2003, 361:1615-1617. This paper from Hong Kong, published early in the SARS outbreak, provided valuable information on treatment options and suggested an effective treatment protocol.
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Lancet
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So, L.K.1
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Ho JC, Ooi GC, Mok TY, et al.: High dose pulse versus non-pulse corticosteroid regimens in severe acute respiratory syndrome. Am J Respir Crit Care Med 2003. One of the first studies to compare treatment options in SARS, this paper demonstrates that high-dose pulse corticosteroids are as safe as and probably more effective than lower dose regimens.
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Am J Respir Crit Care Med
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Ho, J.C.1
Ooi, G.C.2
Mok, T.Y.3
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28
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Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China
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Zhao Z, Zhang F, Xu M, et al.: Description and clinical treatment of an early outbreak of severe acute respiratory syndrome (SARS) in Guangzhou, PR China. J Med Microbiol 2003, 52:715-720. This study of 190 patients from China compares the clinical response to four different treatment regimens, demonstrating a benefit of early administration of high-dose corticosteroids.
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J Med Microbiol
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Sung J: Clinical diagnosis and management of SARS. WHO Global Conference on Severe Acute Respiratory Syndrome (SARS). Available at: http://www.who.int/ csr/sars/conference/june_2003/materials/presentations/ en/clinical_diagnosis. pdf Accessed Sept 4th, 2003.
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WHO Global Conference on Severe Acute Respiratory Syndrome (SARS)
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Sung, J.1
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Wong VWS, Dai D, Wu AKL, Sung JJY: Treatment of severe acute respiratory syndrome with convalescent plasma. Hong Kong Med J 2003, 9:199-201.
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Hong Kong Med J
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Cinatl J, Morgenstern B, Bauer G, et al.: Treatment of SARS with human interferons. Lancet 2003, 362:293-294.
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Lancet
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Lapinsky SE, Hawryluck L: ICU management of severe acute respiratory syndrome. Intensive Care Med 2003, 29:870-875. This review presents an overview of the clinical features and management of critically ill patients with SARS.
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Intensive Care Med
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Lapinsky, S.E.1
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Franks TJ, Chong PY, Chui P, et al.: Lung pathology of severe acute respiratory syndrome (SARS): A study of 8 autopsy cases from Singapore. Hum Pathol 2003, 34:729.
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Hum Pathol
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Nicholls JM, Poon LL, Lee KC, et al.: Lung pathology of fatal severe acute respiratory syndrome. Lancet 2003, 361:1773-1778.
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Lancet
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Mazzulli T, Farcas GA, Poutanen SM, et al.: Severe acute respiratory syndrome-associated coronavirus in lung tissue. Emerg Infect Dis 2004. Available from www.cdc.gov/ncidod/EID/vol10no1/03-0404.htm
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Emerg Infect Dis
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Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS)
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Seto WH, Tsang D, Yung RW, et al.: Effectiveness of precautions against droplets and contact in prevention of nosocomial transmission of severe acute respiratory syndrome (SARS). Lancet 2003, 361:1519-1520. This case-control study from five hospitals in Hong Kong identified droplet spread as the predominant mechanism for disease transmission.
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Lancet
, vol.361
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Seto, W.H.1
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