Molecular mechanisms controlling the development of dopaminergic neurons

Seminars in Cell and Developmental Biology

Volumn 14, Issue 3, 2003, Pages 175-180

  Lin, John C ^a   Rosenthal, Arnon ^a  

^a Rinat Neuroscience Corporation   (United States)

Author keywords

Development; Dopamine; Neuron; Stem cells

Indexed keywords

CELL DIFFERENTIATION; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; FUNCTIONAL MORPHOLOGY; HUMAN; IN VITRO STUDY; MESENCEPHALON; MOLECULAR DYNAMICS; NERVE FIBER; NERVE GROWTH; NONHUMAN; REVIEW; STEM CELL;

EID: 0742305015     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1084-9521(03)00009-0     Document Type: Article

References (52)

1. Lang A.E., Lozano A.M. Parkinson's disease. Second of two parts. N. Engl. J. Med. 339:1998;1130-1143.
2. Dawson T.M., Dawson V.L. Neuroprotective and neurorestorative strategies for Parkinson's disease. Nat. Neurosci. 5:2002;1058-1061.
3. Hynes M., Porter J.A., Chiang C., Chang D., Tessier-Lavigne M., Beachy P.A.et al. Induction of midbrain dopaminergic neurons by Sonic hedgehog. Neuron. 15:1995;35-44.
4. Hynes M., Poulsen K., Tessier-Lavigne M., Rosenthal A. Control of neuronal diversity by the floor plate: contact-mediated induction of midbrain dopaminergic neurons. Cell. 80:1995;95-101.
5. Ye W., Shimamura K., Rubenstein J.L., Hynes M.A., Rosenthal A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell. 93:1998;755-766.
6. Hynes M., Stone D.M., Dowd M., Pitts-Meek S., Goddard A., Gurney A.et al. Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron. 19:1997;15-26.
7. Matise M.P., Epstein D.J., Park H.L., Platt K.A., Joyner A.L. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development. 125:1998;2759-2770.
8. Epstein D.J., McMahon A.P., Joyner A.L. Regionalization of Sonic hedgehog transcription along the anteroposterior axis of the mouse central nervous system is regulated by Hnf3-dependent and -independent mechanisms. Development. 126:1999;281-292.
9. Muller F., Chang B., Albert S., Fischer N., Tora L., Strahle U. Intronic enhancers control expression of zebrafish sonic hedgehog in floor plate and notochord. Development. 126:1999;2103-2116.
10. Epstein D.J., Martinu L., Michaud J.L., Losos K.M., Fan C., Joyner A.L. Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS. Development. 127:2000;4701-4709.
11. Muller F., Albert S., Blader P., Fischer N., Hallonet M., Strahle U. Direct action of the nodal-related signal cyclops in induction of sonic hedgehog in the ventral midline of the CNS. Development. 127:2000;3889-3897.
12. Ye W., Bouchard M., Stone D., Liu X., Vella F., Lee J.et al. Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8. Nat. Neurosci. 4:2001;1175-1181.
13. Rhinn M., Brand M. The midbrain-hindbrain boundary organizer. Curr. Opin. Neurobiol. 11:2001;34-42.
14. Joyner A.L., Liu A., Millet S. Otx2, Gbx2, and Fgf8 interact to position and maintain a mid-hindbrain organizer. Curr. Opin. Cell Biol. 12:2000;736-741.
15. Wurst W., Bally-Cuif L. Neural plate patterning: upstream and downstream of the isthmic organizer. Nat. Rev. Neurosci. 2:2001;99-108.
16. Guo S., Wilson S.W., Cooke S., Chitnis A.B., Driever W., Rosenthal A. Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons. Dev. Biol. (Orlando). 208:1999;473-487.
17. Smidt M.P., van Schaick H.S., Lanctot C., Tremblay J.J., Cox J.J., van der Kleij A.A.et al. A homeodomain gene Ptx3 has highly restricted brain expression in mesencephalic dopaminergic neurons. Proc. Natl. Acad. Sci. U.S.A. 94:1997;13305-13310.
18. Backman C., Perlmann T., Wallen A., Hoffer B.J., Morales M. A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain Res. 851:1999;125-132.
19. Wallen A., Zetterstrom R.H., Solomin L., Arvidsson M., Olson L., Perlmann T. Fate of mesencephalic AHD2-expressing dopamine progenitor cells in Nurr1 mutant mice. Exp. Cell Res. 253:1999;737-746.
20. Saucedo-Cardenas O., Quintana-Hau J.D., Le W.D., Smidt M.P., Cox J.J., De Mayo F.et al. Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc. Natl. Acad. Sci. U.S.A. 95:1998;4013-4018.
21. Witta J., Baffi J.S., Palkovits M., Mezey E., Castillo S.O., Nikodem V.M. Nigrostriatal innervation is preserved in Nurr1-null mice, although dopaminergic neuron precursors are arrested from terminal differentiation. Brain Res. Mol. Brain Res. 84:2000;67-78.
22. Zetterstrom R.H., Solomin L., Jansson L., Hoffer B.J., Olson L., Perlmann T. Dopamine neuron agenesis in Nurr1-deficient mice. Science. 276:1997;248-250.
23. Sakurada K., Ohshima-Sakurada M., Palmer T.D., Gage F.H. Nurr1, an orphan nuclear receptor, is a transcriptional activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain. Development. 126:1999;4017-4026.
24. Wagner J., Akerud P., Castro D.S., Holm P.C., Canals J.M., Snyder E.Y.et al. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat. Biotechnol. 17:1999;653-659.
25. Adams K.A., Maida J.M., Golden J.A., Riddle R.D. The transcription factor Lmx1b maintains Wnt1 expression within the isthmic organizer. Development. 127:2000;1857-1867.
26. Smidt M.P., Asbreuk C.H., Cox J.J., Chen H., Johnson R.L., Burbach J.P. A second independent pathway for development of mesencephalic dopaminergic neurons requires Lmx1b. Nat. Neurosci. 3:2000;337-341.
27. Simon H.H., Saueressig H., Wurst W., Goulding M.D., O'Leary D.D. Fate of midbrain dopaminergic neurons controlled by the engrailed genes. J. Neurosci. 21:2001;3126-3134.
28. Abeliovich A., Schmitz Y., Farinas I., Choi-Lundberg D., Ho W.H., Castillo P.E.et al. Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron. 25:2000;239-252.
29. Moore M.W., Klein R.D., Farinas I., Sauer H., Armanini M., Phillips H.et al. Renal and neuronal abnormalities in mice lacking GDNF. Nature. 382:1996;76-79.
30. Granholm A.C., Reyland M., Albeck D., Sanders L., Gerhardt G., Hoernig G.et al. Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons. J. Neurosci. 20:2000;3182-3190.
31. Blum M. A null mutation in TGF-alpha leads to a reduction in midbrain dopaminergic neurons in the substantia nigra. Nat. Neurosci. 1:1998;374-377.
32. McCaffery P., Drager U.C. High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system. Proc. Natl. Acad. Sci. U.S.A. 91:1994;7772-7776.
33. Nakamura S., Ito Y., Shirasaki R., Murakami F. Local directional cues control growth polarity of dopaminergic axons along the rostrocaudal axis. J. Neurosci. 20:2000;4112-4119.
34. Vitalis T., Cases O., Engelkamp D., Verney C., Price D.J. Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. J. Neurosci. 20:2000;6501-6516.
35. Rajagopalan S., Vivancos V., Nicolas E., Dickson B.J. Selecting a longitudinal pathway: robo receptors specify the lateral position of axons in the Drosophila CNS. Cell. 103:2000;1033-1045.
36. Bagri A., Marin O., Plump A.S., Mak J., Pleasure S.J., Rubenstein J.L., Tessier-Lavigne M. Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron. 33:2002;233-248.
37. Yue Y., Widmer D.A., Halladay A.K., Cerretti D.P., Wagner G.C., Dreyer J.L.et al. Specification of distinct dopaminergic neural pathways: roles of the Eph family receptor EphB1 and ligand ephrin-B2. J. Neurosci. 19:1999;2090-2101.
38. Lee S.H., Lumelsky N., Studer L., Auerbach J.M., McKay R.D. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat. Biotechnol. 18:2000;675-679.
39. Wakayama T., Tabar V., Rodriguez I., Perry A.C., Studer L., Mombaerts P. Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science. 292:2001;740-743.
40. Kim J.H., Auerbach J.M., Rodriguez-Gomez J.A., Velasco I., Gavin D., Lumelsky N.et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature. 418:2002;50-56.
41. Bjorklund L.M., Sanchez-Pernaute R., Chung S., Andersson T., Chen I.Y., McNaught K.S.et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc. Natl. Acad. Sci. U.S.A. 99:2002;2344-2349.
42. Kawasaki H., Mizuseki K., Nishikawa S., Kaneko S., Kuwana Y., Nakanishi S.et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron. 28:2000;31-40.
43. Hynes M., Rosenthal A. Embryonic stem cells go dopaminergic. Neuron. 28:2000;11-14.
44. Kawasaki H., Suemori H., Mizuseki K., Watanabe K., Urano F., Ichinose H.et al. Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc. Natl. Acad. Sci. U.S.A. 99:2002;1580-1585.
45. Wichterle H., Lieberam I., Porter J.A., Jessell T.M. Directed differentiation of embryonic stem cells into motor neurons. Cell. 110:2002;385-397.
46. Lie D.C., Dziewczapolski G., Willhoite A.R., Kaspar B.K., Shults C.W., Gage F.H. The adult substantia nigra contains progenitor cells with neurogenic potential. J. Neurosci. 22:2002;6639-6649.
47. Sanchez-Pernaute R., Studer L., Bankiewicz K.S., Major E.O., McKay R.D. In vitro generation and transplantation of precursor-derived human dopamine neurons. J. Neurosci. Res. 65:2001;284-288.
48. Storch A., Paul G., Csete M., Boehm B.O., Carvey P.M., Kupsch A.et al. Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells. Exp. Neurol. 170:2001;317-325.
49. Sawamoto K., Nakao N., Kakishita K., Ogawa Y., Toyama Y., Yamamoto A.et al. Generation of dopaminergic neurons in the adult brain from mesencephalic precursor cells labeled with a nestin-GFP transgene. J. Neurosci. 21:2001;3895-3903.
50. Studer L., Csete M., Lee S.H., Kabbani N., Walikonis J., Wold B.et al. Enhanced proliferation, survival and dopaminergic differentiation of CNS precursors in lowered oxygen. J. Neurosci. 20:2000;7377-7383.
51. Morrison S.J., Csete M., Groves A.K., Melega W., Wold B., Anderson D.J. Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells. J. Neurosci. 20:2000;7370-7376.
52. Sawamoto K., Nakao N., Kobayashi K., Matsushita N., Takahashi H., Kakishita K.et al. Visualization direct isolation, and transplantation of midbrain dopaminergic neurons. Proc. Natl. Acad. Sci. U.S.A. 98:2001;6423-6428.