α-Tocopherol influences the lipid membrane affinity of desipramine in a pH-dependent manner

European Journal of Pharmaceutical Sciences

Volumn 21, Issue 2-3, 2004, Pages 313-321

  Marenchino, Marco ^a   Alpstäg Wöhrle, Andrea L ^a   Christen, Barbara ^a   Wunderli Allenspach, Heidi ^a   Krämer, Stefanie D ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

Desipramine; Hydrogen bonding; Liposomes; Partitioning; Phospholipidosis; Tocopherol

Indexed keywords

6 HYDROXY 2,2,5,7,8 PENTAMETHYLCHROMAN; ACETIC ACID; ALPHA TOCOPHEROL; BUFFER; CHOLESTEROL; DESIPRAMINE; LIPOSOME; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROPRANOLOL;

ACIDITY; ALKALINITY; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION COEFFICIENT; DIALYSIS; DRUG EFFECT; EGG; IONIZATION; LIPID COMPOSITION; LIPID MEMBRANE; MEMBRANE PERMEABILITY; NONHUMAN; PARTITION CHROMATOGRAPHY; PRIORITY JOURNAL; SYSTEM ANALYSIS; WHEAT;

EID: 0742287064     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2003.10.022     Document Type: Article

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