Viral delivery of P450 reductase recapitulates the ability of constitutive overexpression of reductase enzymes to potentiate the activity of mitomycin C in human breast cancer xenografts

Molecular Cancer Therapeutics

Volumn 2, Issue 9, 2003, Pages 901-909

  Cowen, Rachel L ^a   Patterson, Adam V ^a,b   Telfer, Brian A ^a   Airley, Rachel E ^c   Hobbs, Steve ^d   Phillips, Roger M ^e   Jaffar, Mohammed ^a   Stratford, Ian J ^a   Williams, Kaye J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^e UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DNA; MITOMYCIN; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE;

ADENOVIRUS; ANIMAL; ARTICLE; BIOSYNTHESIS; CELL CULTURE; DRUG DELIVERY SYSTEM; DRUG POTENTIATION; DRUG RESISTANCE; DRUG SCREENING; ENZYME IMMUNOASSAY; ENZYMOLOGY; EXPERIMENTAL NEOPLASM; FEMALE; GENE VECTOR; GENETICS; HUMAN; METABOLISM; MOUSE; NUDE MOUSE; TRANSPLANTATION; XENOGRAFT;

ADENOVIRIDAE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DNA, NEOPLASM; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; FEMALE; GENETIC VECTORS; HUMANS; IMMUNOENZYME TECHNIQUES; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; MITOMYCIN; NAD(P)H DEHYDROGENASE (QUINONE); NADPH-FERRIHEMOPROTEIN REDUCTASE; OXYGEN; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0642379637     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: None     Document Type: Article

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