Molecular mechanism of ureteric bud development

Seminars in Cell and Developmental Biology

Volumn 14, Issue 4, 2003, Pages 217-224

  Sakurai, Hiroyuki ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Branching morphogenesis; Extracellular matrix; Glial cell line derived neurotrophic factor; Matrix metalloproteinases; Metanephric mesenchyme

Indexed keywords

EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR; FRIZZLED PROTEIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MATRIX METALLOPROTEINASE; PLEIOTROPHIN; PROTEINASE; SCATTER FACTOR; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN; CARRIER PROTEIN; CYTOKINE; GDNF PROTEIN, HUMAN; NERVE GROWTH FACTOR;

BRANCHING MORPHOGENESIS; EMBRYONIC STRUCTURES; EPITHELIUM; EXTRACELLULAR MATRIX; GENE MUTATION; HUMAN; IN VITRO STUDY; KIDNEY COLLECTING TUBULE; KIDNEY DEVELOPMENT; MESENCHYME; MOLECULAR MECHANICS; MORPHOGENESIS; NONHUMAN; REVIEW; SIGNAL TRANSDUCTION; URETER BUD; ANIMAL; BIOLOGICAL MODEL; MESODERM; METABOLISM; MUTATION; PHYSIOLOGY; PRENATAL DEVELOPMENT; URETER;

WOLFFIA;

ANIMALS; BODY PATTERNING; CARRIER PROTEINS; CYTOKINES; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HEPATOCYTE GROWTH FACTOR; HUMANS; MESODERM; MODELS, BIOLOGICAL; MUTATION; NERVE GROWTH FACTORS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; URETER;

EID: 0642343228     PISSN: 10849521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1084-9521(03)00024-7     Document Type: Article

References (75)

1. Kamba T., Higashi S., Kamoto T., Shisa H., Yamada Y., Ogawa O.et al. Failure of ureteric bud invasion: a new model of renal agenesis in mice. Am. J. Pathol. 159:2001;2347-2353.
2. Maas R., Elfering S., Glaser T., Jepeal L. Deficient outgrowth of the ureteric bud underlies the renal agenesis phenotype in mice manifesting the limb deformity (ld) mutation. Dev. Dyn. 199:1994;214-228.
3. Wynshaw-Boris A., Ryan G., Deng C.X., Chan D.C., Jackson-Grusby L., Larson D.et al. The role of a single formin isoform in the limb and renal phenotypes of limb deformity. Mol. Med. 3:1997;372-384.
4. Kreidberg J.A., Sariola H., Loring J.M., Maeda M., Pelletier J., Housman D.et al. WT-1 is required for early kidney development. Cell. 74:1993;679-691.
5. Donovan M.J., Natoli T.A., Sainio K., Amstutz A., Jaenisch R., Sariola H.et al. Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud. Dev. Genet. 24:1999;252-262.
6. Durbec P., Marcos-Gutierrez C.V., Kilkenny C., Grigoriou M., Wartiowaara K., Suvanto P.et al. GDNF signalling through the Ret receptor tyrosine kinase. Nature. 381:1996;789-793.
7. Enomoto H., Araki T., Jackman A., Heuckeroth R.O., Snider W.D., Johnson E.M. Jr.et al. GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. Neuron. 21:1998;317-324.
8. Moore M.W., Klein R.D., Farinas I., Sauer H., Armanini M., Phillips H.et al. Renal and neuronal abnormalities in mice lacking GDNF. Nature. 382:1996;76-79.
9. Pichel J.G., Shen L., Sheng H.Z., Granholm A.C., Drago J., Grinberg A.et al. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. 382:1996;73-76.
10. Sanchez M.P., Silos-Santiago I., Frisen J., He B., Lira S.A., Barbacid M. Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature. 382:1996;70-73.
11. Schuchardt A., D'Agati V.D., Pachnis V., Costantini F. Renal agenesis and hypodysplasia in ret-k-mutant mice result from defects in ureteric bud development. Development. 122:1996;1919-1929.
12. Vega Q.C., Worby C.A., Lechner M.S., Dixon J.E., Dressler G.R. Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc. Natl. Acad. Sci. U.S.A. 93:1996;10657-10661.
13. Sainio K., Suvanto P., Davies J., Wartiovaara J., Wartiovaara K., Saarma M.et al. Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development. 124:1997;4077-4087.
14. Kume T., Deng K., Hogan B.L. Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract. Development. 127:2000;1387-1395.
15. Xu P.X., Adams J., Peters H., Brown M.C., Heaney S., Maas R. Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia. Nat. Genet. 23:1999;113-117.
16. Torres M., Gomez-Pardo E., Dressler G.R., Gruss P. Pax-2 controls multiple steps of urogenital development. Development. 121:1995;4057-4065.
17. Brophy P.D., Ostrom L., Lang K.M., Dressler G.R. Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene. Development. 128:2001;4747-4756.
18. Wellik D.M., Hawkes P.J., Capecchi M.R. Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev. 16:2002;1423-1432.
19. Nishinakamura R., Matsumoto Y., Nakao K., Nakamura K., Sato A., Copeland N.G.et al. Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development. 128:2001;3105-3115.
20. Miyamoto N., Yoshida M., Kuratani S., Matsuo I., Aizawa S. Defects of urogenital development in mice lacking Emx2. Development. 124:1997;1653-1664.
21. Torban E., Eccles M.R., Favor J., Goodyer P.R. PAX2 suppresses apoptosis in renal collecting duct cells. Am. J. Pathol. 157:2000;833-842.
22. Miyazaki Y., Oshima K., Fogo A., Hogan B.L., Ichikawa I. Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter. J. Clin. Invest. 105:2000;863-873.
23. Qiao J., Sakurai H., Nigam S.K. Branching morphogenesis independent of mesenchymal-epithelial contact in the developing kidney. Proc. Natl. Acad. Sci. U.S.A. 96:1999;7330-7335.
24. Sakurai H., Barros E.J., Tsukamoto T., Barasch J., Nigam S.K. An in vitro tubulogenesis system using cell lines derived from the embryonic kidney shows dependence on multiple soluble growth factors. Proc. Natl. Acad. Sci. U.S.A. 94:1997;6279-6284.
25. Patterson L.T., Pembaur M., Potter S.S. Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney. Development. 128:2001;2153-2161.
26. Sakurai H., Bush K.T., Nigam S.K. Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis. Development. 128:2001;3283-3293.
27. Rauvala H., Vanhala A., Castren E., Nolo R., Raulo E., Merenmies J.et al. Expression of HB-GAM (heparin-binding growth-associated molecules) in the pathways of developing axonal processes in vivo and neurite outgrowth in vitro induced by HB-GAM. Brain Res. Dev. Brain Res. 79:1994;157-176.
28. Li Y.S., Milner P.G., Chauhan A.K., Watson M.A., Hoffman R.M., Kodner C.M.et al. Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science. 250:1990;1690-1694.
29. Mitsiadis T.A., Salmivirta M., Muramatsu T., Muramatsu H., Rauvala H., Lehtonen E.et al. Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. Development. 121:1995;37-51.
30. Szabat E., Rauvala H. Role of HB-GAM (heparin-binding growth-associated molecule) in proliferation arrest in cells of the developing rat limb and its expression in the differentiating neuromuscular system. Dev. Biol. 178:1996;77-89.
31. Souttou B., Ahmad S., Riegel A.T., Wellstein A. Signal transduction pathways involved in the mitogenic activity of pleiotrophin. Implication of mitogen-activated protein kinase and phosphoinositide 3-kinase pathways. J. Biol. Chem. 272:1997;19588-19593.
32. Amet L.E., Lauri S.E., Hienola A., Croll S.D., Lu Y., Levorse J.M.et al. Enhanced hippocampal long-term potentiation in mice lacking heparin-binding growth-associated molecule. Mol. Cell Neurosci. 17:2001;1014-1024.
33. Wodarz A., Nusse R. Mechanisms of Wnt signaling in development. Annu. Rev. Cell Dev. Biol. 14:1998;59-88.
34. Cadigan K.M., Nusse R. Wnt signaling: a common theme in animal development. Genes Dev. 11:1997;3286-3305.
35. Kispert A., Vainio S., Shen L., Rowitch D.H., McMahon A.P. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development. 122:1996;3627-3637.
36. Stark K., Vainio S., Vassileva G., McMahon A.P. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature (London). 372:1994;679-683.
37. Lin Y., Liu A., Zhang S., Ruusunen T., Kreidberg J.A., Peltoketo H.et al. Induction of ureter branching as a response to Wnt-2b signaling during early kidney organogenesis. Dev. Dyn. 222:2001;26-39.
38. Jones S.E., Jomary C. Secreted Frizzled-related proteins: searching for relationships and patterns. Bioessays. 24:2002;811-820.
39. Lescher B., Haenig B., Kispert A. sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney. Dev. Dyn. 213:1998;440-451.
40. Yoshino K., Rubin J.S., Higinbotham K.G., Uren A., Anest V., Plisov S.Y.et al. Secreted Frizzled-related proteins can regulate metanephric development. Mech. Dev. 102:2001;45-55.
41. Cancilla B., Ford-Perriss M.D., Bertram J.F. Expression and localization of fibroblast growth factors and fibroblast growth factor receptors in the developing rat kidney. Kidney Int. 56:1999;2025-2039.
42. Qiao J., Uzzo R., Obara-Ishihara T., Degenstein L., Fuchs E., Herzlinger D. FGF-7 modulates ureteric bud growth and nephron number in the developing kidney. Development. 126:1999;547-554.
43. Ohuchi H., Hori Y., Yamasaki M., Harada H., Sekine K., Kato S.et al. FGF10 acts as a major ligand for FGF receptor 2 IIIb in mouse multi-organ development. Biochem. Biophys. Res. Commun. 277:2000;643-649.
44. Hatini V., Huh S.O., Herzlinger D., Soares V.C., Lai E. Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. Genes Dev. 10:1996;1467-1478.
45. Qiao J., Bush K.T., Steer D.L., Stuart R.O., Sakurai H., Wachsman W.et al. Multiple fibroblast growth factors support growth of the ureteric bud but have different effects on branching morphogenesis. Mech. Dev. 109:2001;123-135.
46. Cardoso W.V., Itoh A., Nogawa H., Mason I., Brody J.S. FGF-1 and FGF-7 induce distinct patterns of growth and differentiation in embryonic lung epithelium. Dev. Dyn. 208:1997;398-405.
47. Rogers S.A., Ryan G., Purchio A.F., Hammerman M.R. Metanephric transforming growth factor-beta 1 regulates nephrogenesis in vitro. Am. J. Physiol. 264:1993;F996-1002.
48. Ritvos O., Tuuri T., Eramaa M., Sainio K., Hilden K., Saxen L.et al. Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse. Mech. Dev. 50:1995;229-245.
49. Piscione T.D., Yager T.D., Gupta I.R., Grinfeld B., Pei Y., Attisano L. et al. BMP-2 and OP-1 exert direct and opposite effects on renal branching morphogenesis. Am. J. Physiol. 273:1997;F961-75.
50. Sakurai H., Nigam S.K. Transforming growth factor-beta selectively inhibits branching morphogenesis but not tubulogenesis. Am. J. Physiol. 272:1997;F139-46.
51. Montesano R., Matsumoto K., Nakamura T., Orci L. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell. 67:1991;901-908.
52. Santos O.F., Barros E.J., Yang X.M., Matsumoto K., Nakamura T., Park M. et al. Involvement of hepatocyte growth factor in kidney development. Dev. Biol. 163:1994;525-529.
53. Woolf A.S., Kolatsi-Joannou M., Hardman P., Andermarcher E., Moorby C., Fine L.G.et al. Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J. Cell Biol. 128:1995;171-184.
54. Schmidt C., Bladt F., Goedecke S., Brinkmann V., Zschiesche W., Sharpe M.et al. Scatter factor/hepatocyte growth factor is essential for liver development. Nature (London). 373:1995;699-702.
55. Bladt F., Riethmacher D., Isenmann S., Aguzzi A., Birchmeier C. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature. 376:1995;768-771.
56. Sakurai H., Tsukamoto T., Kjelsberg C.A., Cantley L.G., Nigam S.K. EGF receptor ligands are a large fraction of in vitro branching morphogens secreted by embryonic kidney. Am. J. Physiol. 273:1997;F463-72.
57. Threadgill D.W., Dlugosz A.A., Hansen L.A., Tennenbaum T., Lichti U., Yee D.et al. Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science. 269:1995;230-234.
58. Takemura T., Hino S., Okada M., Murata Y., Yanagida H., Ikeda M.et al. Role of membrane-bound heparin-binding epidermal growth factor-like growth factor (HB-EGF) in renal epithelial cell branching. Kidney Int. 61:2002;1968-1979.
59. Santos O.F., Nigam S.K. HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-beta. Dev. Biol. 160:1993;293-302.
60. Pohl M., Sakurai H., Stuart R.O., Nigam S.K. Role of hyaluronan and CD44 in in vitro branching morphogenesis of ureteric bud cells. Dev. Biol. 224:2000;312-325.
61. Zent R., Bush K.T., Pohl M.L., Quaranta V., Koshikawa N., Wang Z.et al. Involvement of laminin binding integrins and laminin-5 in branching morphogenesis of the ureteric bud during kidney development. Dev. Biol. 238:2001;289-302.
62. Georges-Labouesse E., Messaddeq N., Yehia G., Cadalbert L., Dierich A., Le Meur M. Absence of integrin alpha 6 leads to epidermolysis bullosa and neonatal death in mice. Nat. Genet. 13:1996;370-373.
63. Kreidberg J.A., Donovan M.J., Goldstein S.L., Rennke H., Shepherd K., Jones R.C.et al. Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis. Development. 122:1996;3537-3547.
64. Karihaloo A., Karumanchi S.A., Barasch J., Jha V., Nickel C.H., Yang J. et al. Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud. Proc. Natl. Acad. Sci. U.S.A. 98:2001;12509-12514.
65. Schlessinger J., Lax I., Lemmon M. Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors? Cell. 83:1995;357-360.
66. Maeda N., Noda M. Involvement of receptor-like protein tyrosine phosphatase zeta/RPTPbeta and its ligand pleiotrophin/heparin-binding growth-associated molecule (HB-GAM) in neuronal migration. J. Cell Biol. 142:1998;203-216.
67. Meng K., Rodriguez-Pena A., Dimitrov T., Chen W., Yamin M., Noda M.et al. Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta. Proc. Natl. Acad. Sci. U.S.A. 97:2000;2603-2608.
68. Cano-Gauci D.F., Song H.H., Yang H., McKerlie C., Choo B., Shi W.et al. Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome. J. Cell Biol. 146:1999;255-264.
69. Davies J., Lyon M., Gallagher J., Garrod D. Sulphated proteoglycan is required for collecting duct growth and branching but not nephron formation during kidney development. Development. 121:1995;1507-1517.
70. Bullock S.L., Fletcher J.M., Beddington R.S., Wilson V.A. Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 12:1998;1894-1906.
71. Pohl M., Sakurai H., Bush K.T., Nigam S.K. Matrix metalloproteinases and their inhibitors regulate in vitro ureteric bud branching morphogenesis. Am. J. Physiol. 279:2000;F891-900.
72. Lelongt B., Trugnan G., Murphy G., Ronco P.M. Matrix metalloproteinases MMP2 and MMP9 are produced in early stages of kidney morphogenesis but only MMP9 is required for renal organogenesis in vitro. J. Cell Biol. 136:1997;1363-1373.
73. Ota K., Stetler-Stevenson W.G., Yang Q., Kumar A., Wada J., Kashihara N.et al. Cloning of murine membrane-type-1-matrix metalloproteinase (MT-1-MMP) and its metanephric developmental regulation with respect to MMP-2 and its inhibitor. Kidney Int. 54:1998;131-142.
74. al-Awqati Q., Goldberg M.R. Architectural patterns in branching morphogenesis in the kidney. Kidney Int. 54:1998;1832-1842.
75. Lin Y., Zhang S., Rehn M., Itaranta P., Tuukkanen J., Heljasvaara R.et al. Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung type: association with sonic hedgehog and ectopic surfactant protein C. Development. 128:2001;1573-1585.