Synthesis and structure-activity relationships of oxime neurokinin antagonists: Discovery of potent arylamides

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 2, 2002, Pages 141-145

  Shih, Neng Yang ^a   Albanese, Margaret ^a   Anthes, John C ^a   Carruthers, Nicholas I ^b   Grice, Cheryl A ^b   Lin, Ling ^a   Mangiaracina, Pietro ^a   Reichard, Gregory A ^a   Schwerdt, John ^a   Seidl, Vera ^a   Wong, Shing Chung ^a   Piwinski, John J ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; BENZILIC ACID; ETHER; NEUROKININ 1 RECEPTOR ANTAGONIST; NEUROKININ 2 RECEPTOR ANTAGONIST; OXIME;

ALKYLATION; AMINATION; ARTICLE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

OXIMES; RECEPTORS, NEUROKININ-1; RECEPTORS, NEUROKININ-2; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 18244363925     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00709-0     Document Type: Article

References (8)