Microbial/enzymatic synthesis of chiral intermediates for pharmaceuticals

Enzyme and Microbial Technology

Volumn 31, Issue 6, 2002, Pages 804-826

  Patel, Ramesh N ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

3 Receptors agonists; Anti Alzheimers; Anticancer; Anticholesterol; Antihypertensive; Antiviral; Biocatalysis; Chiral intermediates; Melatonin receptor agonists

Indexed keywords

AGRICULTURAL PRODUCTS; BIOSYNTHESIS; DRUG PRODUCTS; ENZYMES; TUMORS;

AGROCHEMICAL INDUSTRIES;

MICROORGANISMS;

15 DEOXYSPERGUALIN; 3 (ACETOXY) 1 [2 (DIMETHYLAMINO)ETHYL] 1,3,4,5 TETRAHYDRO 4 (4 METHOXYPHENYL) 6 (TRIFLUOROMETHYL) 2H 1 BENZAZEPIN 2 ONE; [1 (ACETOXYL) 4 (3 PHENYL)BUTYL]PHOSPHONIC ACID; [1 [1ALPHA,2ALPHA,3ALPHA,4ALPHA [7 [3 (1 OXOHEPTYL)AMINE]ACETYL]METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTANOIC ACID; ABACAVIR; ALPHA [(ACETYLTHIO)METHYL]BENZENEPROPANOIC ACID; BETA 3 ADRENERGIC RECEPTOR STIMULATING AGENT; CAPTOPRIL; DILTIAZEM; ESTER DERIVATIVE; FOSINOPRIL; GUANINE ARABINOSIDE; GUANINE DERIVATIVE; HORMONE RECEPTOR STIMULATING AGENT; HYPOCHOLESTEROLEMIC AGENT; INDINAVIR; KETONE DERIVATIVE; LOBUCAVIR; MELATONIN RECEPTOR; METHYL 4 CHLORO 3 OXOBUTANOATE; OMAPATRILAT; PACLITAXEL; POTASSIUM CHANNEL STIMULATING AGENT; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEINASE INHIBITOR; SUCCINIC ANHYDRIDE; TAXUS BREVIFOLIA EXTRACT; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZIAZEN; ZOFENOPRIL;

ALZHEIMER DISEASE; ANGINA PECTORIS; ANTIHYPERTENSIVE ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; BARK; BIOCATALYST; BREAST CARCINOMA; BREAST METASTASIS; CHIRALITY; DRUG BINDING; DRUG SYNTHESIS; ENANTIOSELECTIVITY; ENZYME ACTIVITY; GASTROINTESTINAL DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYDROLYSIS; HYPERCHOLESTEROLEMIA; HYPERTENSION; KINETICS; LEUKEMIA; MEDICINAL PLANT; MOLECULAR DYNAMICS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; OVARY CARCINOMA; OXYGENATION; POLYMERIZATION; REDUCTION; STRUCTURE ACTIVITY RELATION; TAXUS BREVIFOLIA; THROMBOSIS;

EID: 0036843758     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0141-0229(02)00186-2     Document Type: Article

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