Nanomolar concentrations of epothilone D inhibit the proliferation of glioma cells and severely affect their tubulin cytoskeleton

Journal of Neuro-Oncology

Volumn 65, Issue 2, 2003, Pages 99-106

  Dietzmann, A ^a   Kanakis, D ^a   Kirches, Elmar ^a   Kropf, S ^a   Mawrin, C ^a   Dietzmann, K ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Actin; Epo D epothilone; Glioblastoma; Microtubules; MTT assay

Indexed keywords

ACTIN; CYTOTOXIC AGENT; DIMETHYL SULFOXIDE; EPOTHILONE D; MITOXANTRONE; NIMUSTINE; TENIPOSIDE; TETRAZOLIUM; TUBULIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ARTICLE; BIOASSAY; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOMA CELL; CELL COUNT; CELL PROLIFERATION; CELL SHAPE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; DOSE RESPONSE; DRUG CLASSIFICATION; DRUG EFFECT; DRUG EXPOSURE; DRUG POTENCY; GLIOBLASTOMA; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INHIBITION KINETICS; MICROSCOPY; MICROTUBULE; MORPHOLOGY; RECURRENT CANCER; THERAPY RESISTANCE; TREATMENT FAILURE;

ACTINS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL DIVISION; CELL SURVIVAL; CYTOSKELETON; EPOTHILONES; GLIOMA; HUMANS; MICROFILAMENTS; MICROSCOPY, CONFOCAL; MICROTUBULES; TUBULIN; TUMOR CELLS, CULTURED;

EID: 0348135043     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NEON.0000003679.40609.63     Document Type: Article

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