-
1
-
-
0347598336
-
"371 Biotechnology medicines in testing promise to bolster the arsenal against disease"
-
47, PhRMA Survey
-
PhRMA Survey. "371 Biotechnology medicines in testing promise to bolster the arsenal against disease". New Medicines in Development Biotechnology 1-47 (2002).
-
(2002)
New Medicines in Development Biotechnology
, vol.1
-
-
-
2
-
-
0038957346
-
Proteomics: New tools for a new era
-
Edwards, A.M., Arrowsmith, C.H., des Pallieres, B. Proteomics: new tools for a new era. Mod. Drug Discov. 3, 35-44 (2000).
-
(2000)
Mod. Drug Discov.
, vol.3
, pp. 35-44
-
-
Edwards, A.M.1
Arrowsmith, C.H.2
des Pallieres, B.3
-
3
-
-
0346967489
-
Peptides and proteins as parenteral solutions
-
Eds. Frokjaer, S., Hovgaard, L., Taylor & Francis, London
-
Akers, M.J., DeFelippis, M.R. Peptides and proteins as parenteral solutions. In Pharmaceutical Formulation Development of Peptides and Proteins. Eds. Frokjaer, S., Hovgaard, L., Taylor & Francis, London, 145-177 (2000).
-
(2000)
Pharmaceutical Formulation Development of Peptides and Proteins
, pp. 145-177
-
-
Akers, M.J.1
DeFelippis, M.R.2
-
4
-
-
0032851914
-
Future challenges for drug delivery
-
Breimer, D.D. Future challenges for drug delivery. J. Control. Rel. 62, 3-6 (1999).
-
(1999)
J. Control. Rel.
, vol.62
, pp. 3-6
-
-
Breimer, D.D.1
-
5
-
-
0025078913
-
Monomeric insulins and their experimental and clinical implications
-
Brange, J., Owens, D.R., Kang, S., Vølund, A. Monomeric insulins and their experimental and clinical implications. Diabetes Care 13, 923-954 (1990).
-
(1990)
Diabetes Care
, vol.13
, pp. 923-954
-
-
Brange, J.1
Owens, D.R.2
Kang, S.3
Vølund, A.4
-
6
-
-
0035032976
-
Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics
-
DeFelippis, M.R., Chance, R.E., Frank, B.H. Insulin self-association and the relationship to pharmacokinetics and pharmacodynamics. Crit. Rev. Ther. Drug Carrier Syst. 18, 201-264 (2001).
-
(2001)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.18
, pp. 201-264
-
-
DeFelippis, M.R.1
Chance, R.E.2
Frank, B.H.3
-
7
-
-
0027729733
-
The development of stable protein formulations: A close look at protein aggregation, deamidation, and oxidation
-
Cleland, J.L., Powell, M.F., Shire, S.J. The development of stable protein formulations: a close look at protein aggregation, deamidation, and oxidation. Crit. Rev. Ther. Drug Carrier Syst. 10, 307-377 (1993).
-
(1993)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.10
, pp. 307-377
-
-
Cleland, J.L.1
Powell, M.F.2
Shire, S.J.3
-
8
-
-
0033641042
-
The latest developments in insulin injection devices
-
Robertson, K.E., Glazer, N.B., Campbell, R.K. The latest developments in insulin injection devices. Diabetes Educr. 26, 135-152 (2000).
-
(2000)
Diabetes Educr.
, vol.26
, pp. 135-152
-
-
Robertson, K.E.1
Glazer, N.B.2
Campbell, R.K.3
-
9
-
-
0032863151
-
Transdermal and transmucosal powdered drug delivery
-
Burkoth, T.L., Bellhouse, B.J., Hewson, G. Transdermal and transmucosal powdered drug delivery. Crit. Rev. Ther. Drug Carrier Syst. 16, 331-384 (1999).
-
(1999)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.16
, pp. 331-384
-
-
Burkoth, T.L.1
Bellhouse, B.J.2
Hewson, G.3
-
10
-
-
0037795752
-
Crystalline monoclonal antibodies for subcutaneous delivery
-
Yang, M.X., Shenoy, B., Disttler, M, Patel, R., McGrath, M., Pechenov, S., Margolin, A.L. Crystalline monoclonal antibodies for subcutaneous delivery. Proc. Natl. Acad. Sci. 100, 6934-6939 (2003).
-
(2003)
Proc. Natl. Acad. Sci.
, vol.100
, pp. 6934-6939
-
-
Yang, M.X.1
Shenoy, B.2
Disttler, M.3
Patel, R.4
McGrath, M.5
Pechenov, S.6
Margolin, A.L.7
-
11
-
-
0029931545
-
Controlled release of a therapeutic protein
-
Langer, R. Controlled release of a therapeutic protein. Nature Med. 2, 742-743 (1996).
-
(1996)
Nature Med.
, vol.2
, pp. 742-743
-
-
Langer, R.1
-
12
-
-
0035211601
-
Darbepoetin Alfa
-
2001
-
Ibbotson, T., Goa, K.L. Darbepoetin Alfa. Drugs 2001 61, 2097-2104 (2001).
-
(2001)
Drugs
, vol.61
, pp. 2097-2104
-
-
Ibbotson, T.1
Goa, K.L.2
-
13
-
-
12244272391
-
Enhancement of therapeutic protein in vivo activities through glycoengineering
-
Elliott S., Lorenzini, T., Asher, S., Aoki, K., Brankow, D., Buck L., Busse, L., Chang, D., Fuller, J., Grant, J., Hernday, N., Hokum, M., Hu, S., Knudten, A., Levin, N., Komorowski, R., Martin, F., Navarro, R., Osslund, T., Rogers, G., Rogers, N., Trail, G., Egrie, J. Enhancement of therapeutic protein in vivo activities through glycoengineering. Nature Biotech. 21, 414-421 (2003).
-
(2003)
Nature Biotech.
, vol.21
, pp. 414-421
-
-
Elliott, S.1
Lorenzini, T.2
Asher, S.3
Aoki, K.4
Brankow, D.5
Buck, L.6
Busse, L.7
Chang, D.8
Fuller, J.9
Grant, J.10
Hernday, N.11
Hokum, M.12
Hu, S.13
Knudten, A.14
Levin, N.15
Komorowski, R.16
Martin, F.17
Navarro, R.18
Osslund, T.19
Rogers, G.20
Rogers, N.21
Trail, G.22
Egrie, J.23
more..
-
14
-
-
0037362655
-
Effect of pegylation on pharmaceuticals
-
Harris, J.M., Chess, R.B. Effect of pegylation on pharmaceuticals. Nature Rev. 2, 214-221 (2003).
-
(2003)
Nature Rev.
, vol.2
, pp. 214-221
-
-
Harris, J.M.1
Chess, R.B.2
-
15
-
-
0028239031
-
Overcoming enzymatic and absorption barriers to non-parenterally administered protein and peptide drugs
-
Zhou, X.H. Overcoming enzymatic and absorption barriers to non-parenterally administered protein and peptide drugs. J. Control. Rel. 29, 239-252 (1994).
-
(1994)
J. Control. Rel.
, vol.29
, pp. 239-252
-
-
Zhou, X.H.1
-
16
-
-
0024836302
-
Penetration and enzymatic barriers to peptide and protein absorption
-
Lee, V.H.L., Yamamoto, A. Penetration and enzymatic barriers to peptide and protein absorption. Adv. Drug Del. Rev. 4, 171-207 (1990).
-
(1990)
Adv. Drug Del. Rev.
, vol.4
, pp. 171-207
-
-
Lee, V.H.L.1
Yamamoto, A.2
-
17
-
-
0029757133
-
Systemic delivery of peptides and proteins across absorptive mucosae
-
Sayani, A.P., Chien, Y.W. Systemic delivery of peptides and proteins across absorptive mucosae. Crit. Rev. Ther. Drug Carrier Syst. 13, 85-184 (1996).
-
(1996)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.13
, pp. 85-184
-
-
Sayani, A.P.1
Chien, Y.W.2
-
18
-
-
0036803204
-
Mechanisms for absorption enhancement of inhaled insulin by sodium taurocholate
-
Johansson, F., Hjertberg, E., Eirefelt, S., Tronde, A., Bengtsson, U.H. Mechanisms for absorption enhancement of inhaled insulin by sodium taurocholate. Eur. J. Pharm. Sci. 17, 63-71 (2002).
-
(2002)
Eur. J. Pharm. Sci.
, vol.17
, pp. 63-71
-
-
Johansson, F.1
Hjertberg, E.2
Eirefelt, S.3
Tronde, A.4
Bengtsson, U.H.5
-
19
-
-
0032969698
-
Intranasal insulin delivery and therapy
-
Hinchcliffe, M., Illum, L. Intranasal insulin delivery and therapy. Adv. Drug Del. Rev. 35 199-234 (1999).
-
(1999)
Adv. Drug Del. Rev.
, vol.35
, pp. 199-234
-
-
Hinchcliffe, M.1
Illum, L.2
-
20
-
-
0025861067
-
Study of nasal enzyme activity towards insulin in vitro
-
Gizurarson, S., Bechgaard, E. Study of nasal enzyme activity towards insulin. in vitro. Chem. Pharm. Bull. 39, 2155-2157 (1991).
-
(1991)
Chem. Pharm. Bull.
, vol.39
, pp. 2155-2157
-
-
Gizurarson, S.1
Bechgaard, E.2
-
23
-
-
0034844734
-
Alternative routes of administration as an approach to improve insulin therapy: Update on dermal, oral, nasal, and pulmonary insulin delivery
-
Heinemann, L., Pfützner, A., Heise, T. Alternative routes of administration as an approach to improve insulin therapy: update on dermal, oral, nasal, and pulmonary insulin delivery. Curr. Pharm. Design 7, 1327-1351 (2001).
-
(2001)
Curr. Pharm. Design
, vol.7
, pp. 1327-1351
-
-
Heinemann, L.1
Pfützner, A.2
Heise, T.3
-
24
-
-
0036633358
-
New horizons - Alternative routes for insulin therapy
-
Owens, D.R. New horizons - alternative routes for insulin therapy. Nature Rev. 1, 529-540 (2002).
-
(2002)
Nature Rev.
, vol.1
, pp. 529-540
-
-
Owens, D.R.1
-
25
-
-
0025952084
-
Developments in buccal drug delivery
-
de Vries, M.E., Boddé, H.E., Verhoef, J.C., Junginger, H.E. Developments in buccal drug delivery. Crit. Rev. Ther. Drug Carrier Syst. 8, 217-303 (1991).
-
(1991)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.8
, pp. 217-303
-
-
de Vries, M.E.1
Boddé, H.E.2
Verhoef, J.C.3
Junginger, H.E.4
-
26
-
-
0035132416
-
Factors and strategies for improving buccal absorption of peptides
-
Veuillez, F., Kalia, Y.N., Jacques, Y., Deshusses, J., Buri, P. Factors and strategies for improving buccal absorption of peptides. Eur. J. Pharmaceut. Biopharm. 51, 93-109 (2001).
-
(2001)
Eur. J. Pharmaceut. Biopharm.
, vol.51
, pp. 93-109
-
-
Veuillez, F.1
Kalia, Y.N.2
Jacques, Y.3
Deshusses, J.4
Buri, P.5
-
27
-
-
0035019608
-
Delivery of bioactive peptides and proteins across oral (buccal) mucosa
-
Senel, S., Kremer, M., Nagy, K., Squier, C. Delivery of bioactive peptides and proteins across oral (buccal) mucosa. Curr. Pharm. Biotech. 2, 175-186 (2001).
-
(2001)
Curr. Pharm. Biotech.
, vol.2
, pp. 175-186
-
-
Senel, S.1
Kremer, M.2
Nagy, K.3
Squier, C.4
-
28
-
-
0037148692
-
Peptidase activity on the surface of porcine buccal mucosa
-
Walker, G.F, Langoth, N., Bernkop-Schnürch, A. Peptidase activity on the surface of porcine buccal mucosa. Int. J. Pharmceut. 233, 141-147 (2002).
-
(2002)
Int. J. Pharmceut.
, vol.233
, pp. 141-147
-
-
Walker, G.F.1
Langoth, N.2
Bernkop-Schnürch, A.3
-
29
-
-
0026564618
-
Drug delivery via the mucous membranes of the oral cavity
-
Harris, D., Robinson, J.R. Drug delivery via the mucous membranes of the oral cavity. J. Pharm. Sci. 81, 1-10 (1992).
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 1-10
-
-
Harris, D.1
Robinson, J.R.2
-
30
-
-
0030776130
-
GLP-1 tablet in type 2 diabetes in fasting and postprandial conditions
-
Gutniak, M.K., Larsson, H., Sanders, S.W., Juneskans, O., Holst, J.J., Ahrén, B. GLP-1 tablet in type 2 diabetes in fasting and postprandial conditions. Diabetes Care 20, 1874-1879 (1997).
-
(1997)
Diabetes Care
, vol.20
, pp. 1874-1879
-
-
Gutniak, M.K.1
Larsson, H.2
Sanders, S.W.3
Juneskans, O.4
Holst, J.J.5
Ahrén, B.6
-
31
-
-
0036103168
-
The evolving role of oral insulin in the treatment of diabetes using a novel RapidMist™ system
-
Modi, P., Mihic, M., Lewin, A. The evolving role of oral insulin in the treatment of diabetes using a novel RapidMist™ system. Diabetes Metab. Res. Rev. 18, S38-S42 (2002).
-
(2002)
Diabetes Metab. Res. Rev.
, vol.18
-
-
Modi, P.1
Mihic, M.2
Lewin, A.3
-
32
-
-
0034282141
-
Transdermal drug delivery: Overcoming the skin's barrier function
-
Naik, A., Kalia, Y.N., Guy, R.H. Transdermal drug delivery: overcoming the skin's barrier function. Pharm. Sci. Technol. Today. 3, 318-326 (2000).
-
(2000)
Pharm. Sci. Technol. Today
, vol.3
, pp. 318-326
-
-
Naik, A.1
Kalia, Y.N.2
Guy, R.H.3
-
33
-
-
0031214278
-
Transdermal therapy and diagnosis by iontophoresis
-
Merino, V., Kalia, Y.N., Guy, R.H. Transdermal therapy and diagnosis by iontophoresis. TIBTECH 15, 288-290 (1997).
-
(1997)
TIBTECH
, vol.15
, pp. 288-290
-
-
Merino, V.1
Kalia, Y.N.2
Guy, R.H.3
-
34
-
-
0031047867
-
Drug Reservoir Composition and Transport of Salmon Calcitonin in Transdermal Iontophoresis
-
Santi, P., Colombo, P., Bettini, R., Catellani, P.L., Minutello, A., Volpato, N.M., Drug Reservoir Composition and Transport of Salmon Calcitonin in Transdermal Iontophoresis. Pharm. Res. 14, 63-66 (1997).
-
(1997)
Pharm. Res.
, vol.14
, pp. 63-66
-
-
Santi, P.1
Colombo, P.2
Bettini, R.3
Catellani, P.L.4
Minutello, A.5
Volpato, N.M.6
-
35
-
-
0032559176
-
Iontophoresis of monomeric insulin analogues in vitro: Effects of insulin charge and skin pretreatment
-
Langkjœr, L., Brange, J., Grodsky, G.M., Guy, R.H. Iontophoresis of monomeric insulin analogues in vitro: effects of insulin charge and skin pretreatment. J. Control. Rel. 51, 47-56 (1998).
-
(1998)
J. Control. Rel.
, vol.51
, pp. 47-56
-
-
Langkjœr, L.1
Brange, J.2
Grodsky, G.M.3
Guy, R.H.4
-
36
-
-
0029125922
-
Ultrasound-mediated transdermal protein delivery
-
Mitragotri, S., Blankschtein, D., Langer R. Ultrasound-mediated transdermal protein delivery. Science 269, 850-853 (1995).
-
(1995)
Science
, vol.269
, pp. 850-853
-
-
Mitragotri, S.1
Blankschtein, D.2
Langer, R.3
-
37
-
-
0030470587
-
Transfersomes, liposomes and other lipid suspensions on the skin: Permeation enhancement, vesicle penetration, and transdermal drug delivery
-
Cevc, G. Transfersomes, liposomes and other lipid suspensions on the skin: permeation enhancement, vesicle penetration, and transdermal drug delivery. Crit. Rev. Ther. Drug Carrier Syst. 13, 257-388 (1996).
-
(1996)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.13
, pp. 257-388
-
-
Cevc, G.1
-
38
-
-
24544464769
-
Transdermal insulin infusion through thermally created micropores in humans
-
Smith, A.M., Eppstein, J.A., Delcher, H.K., McRae, M.S., Woods, T.J., Williams, D.J., Hatch, M.R. Transdermal insulin infusion through thermally created micropores in humans. Diabetes 50, A132 (2001).
-
(2001)
Diabetes
, vol.50
-
-
Smith, A.M.1
Eppstein, J.A.2
Delcher, H.K.3
McRae, M.S.4
Woods, T.J.5
Williams, D.J.6
Hatch, M.R.7
-
39
-
-
0034578084
-
Microfabricated microneedles for gene and drug delivery
-
McAllister, D.V., Allen, M.G., Prausnitz, M.R. Microfabricated microneedles for gene and drug delivery. Annu. Rev. Biomed. Eng. 2, 289-313 (2000).
-
(2000)
Annu. Rev. Biomed. Eng.
, vol.2
, pp. 289-313
-
-
McAllister, D.V.1
Allen, M.G.2
Prausnitz, M.R.3
-
40
-
-
0032404493
-
The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals
-
Pettit, D.K., Gombotz, W.R. The development of site-specific drug-delivery systems for protein and peptide biopharmaceuticals. TIBTECH 16, 343-349 (1998).
-
(1998)
TIBTECH
, vol.16
, pp. 343-349
-
-
Pettit, D.K.1
Gombotz, W.R.2
-
41
-
-
0033394538
-
rhDNase therapy for the treatment of cystic fibrosis patients with mild to moderate lung disease
-
Christopher, F., Chase, D., Stein, K., Milne, R. rhDNase therapy for the treatment of cystic fibrosis patients with mild to moderate lung disease. J. Clin. Pharmacy Therapeut. 24, 415-426 (1999).
-
(1999)
J. Clin. Pharmacy Therapeut.
, vol.24
, pp. 415-426
-
-
Christopher, F.1
Chase, D.2
Stein, K.3
Milne, R.4
-
42
-
-
0343058935
-
Mechanisms of macromolecule absorption by the lungs
-
Patton, J.S. Mechanisms of macromolecule absorption by the lungs. Adv. Drug Del. Rev. 19, 3-36 (1996).
-
(1996)
Adv. Drug Del. Rev.
, vol.19
, pp. 3-36
-
-
Patton, J.S.1
-
43
-
-
0022539757
-
Prediction of drug residence times in regions of the human respiratory tract following aerosol inhalation
-
Byron, P.R. Prediction of drug residence times in regions of the human respiratory tract following aerosol inhalation. J. Pharm. Sci. 75, 433-438 (1986).
-
(1986)
J. Pharm. Sci.
, vol.75
, pp. 433-438
-
-
Byron, P.R.1
-
44
-
-
0034918105
-
2001: An odyssey in inhaler formulation and design
-
Crowder, T.M., Louey, M.D., Sethuraman, V.V., Smyth, H.D.C., Hickey, A.J. 2001: an odyssey in inhaler formulation and design. Pharm. Tech. 25, 99-113 (2001).
-
(2001)
Pharm. Tech.
, vol.25
, pp. 99-113
-
-
Crowder, T.M.1
Louey, M.D.2
Sethuraman, V.V.3
Smyth, H.D.C.4
Hickey, A.J.5
-
45
-
-
10744227569
-
Large porous particles for pulmonary drug delivery
-
Edwards, D.A., Hanes, J., Caponetti, G., Hrkach, J., Ben-Jebria, A., Eskew, M.L., Mintzes, J., Deaver, D., Lotan, X., Langer, R. Large porous particles for pulmonary drug delivery. Science 276, 1868-1871 (1997).
-
(1997)
Science
, vol.276
, pp. 1868-1871
-
-
Edwards, D.A.1
Hanes, J.2
Caponetti, G.3
Hrkach, J.4
Ben-Jebria, A.5
Eskew, M.L.6
Mintzes, J.7
Deaver, D.8
Lotan, X.9
Langer, R.10
-
46
-
-
0031904113
-
Recent advances in pulmonary drug delivery using large, porous inhaled particles
-
Edwards, D.A., Ben-Jebria, A., Langer, R. Recent advances in pulmonary drug delivery using large, porous inhaled particles. J. Appl. Physiol. 84, 379-385 (1998).
-
(1998)
J. Appl. Physiol.
, vol.84
, pp. 379-385
-
-
Edwards, D.A.1
Ben-Jebria, A.2
Langer, R.3
-
47
-
-
0032734092
-
Formulation and physical characterization of large porous particles for inhalation
-
Vanbever, R., Mintzes, J.D., Wang, J., Nice J,. Chen, D., Batycky, R., Langer, R., Edwards, D.A. Formulation and physical characterization of large porous particles for inhalation. Pharm. Res. 16, 1735-1742 (1999).
-
(1999)
Pharm. Res.
, vol.16
, pp. 1735-1742
-
-
Vanbever, R.1
Mintzes, J.D.2
Wang, J.3
Nice, J.4
Chen, D.5
Batycky, R.6
Langer, R.7
Edwards, D.A.8
-
48
-
-
0011828819
-
Pulmonary bioavailability of LH-RH analogs: Some biopharmaceutical guidelines
-
Adjei, A.L., Carrigan, P.J. Pulmonary bioavailability of LH-RH analogs: some biopharmaceutical guidelines. J. Biopharm. Sci. 3, 247-254 (1992).
-
(1992)
J. Biopharm. Sci.
, vol.3
, pp. 247-254
-
-
Adjei, A.L.1
Carrigan, P.J.2
-
49
-
-
0028087664
-
Drug delivery via the respiratory tract
-
Byron, P.R., Patton, J.S. Drug delivery via the respiratory tract. J. Aerosol Med. 7, 49-75 (1994).
-
(1994)
J. Aerosol Med.
, vol.7
, pp. 49-75
-
-
Byron, P.R.1
Patton, J.S.2
-
50
-
-
0032969699
-
Inhaled insulin
-
Patton, J.S., Bukar, J., Nagarajan, S. Inhaled insulin. Adv. Drug Del. Rev. 35, 235-247 (1999).
-
(1999)
Adv. Drug Del. Rev.
, vol.35
, pp. 235-247
-
-
Patton, J.S.1
Bukar, J.2
Nagarajan, S.3
-
51
-
-
0030614874
-
Time-action profile of inhaled insulin
-
Heinemann, L., Traut, T., Heise, T. Time-action profile of inhaled insulin. Diabetic Med. 14, 63-72 (1997).
-
(1997)
Diabetic Med.
, vol.14
, pp. 63-72
-
-
Heinemann, L.1
Traut, T.2
Heise, T.3
-
52
-
-
0035798916
-
Efficacy of inhaled human insulin in type 1 diabetes mellitus: A randomized proof-of-concept study
-
Skyler J.S., Cefalu, W.T., Kourides, I.A., Landschulz, W.H., Balagtas, C.C., Cheng, S.-L., Gelfand, R.A. Efficacy of inhaled human insulin in type 1 diabetes mellitus: a randomized proof-of-concept study. Lancet 357, 331-335 (2001).
-
(2001)
Lancet
, vol.357
, pp. 331-335
-
-
Skyler, J.S.1
Cefalu, W.T.2
Kourides, I.A.3
Landschulz, W.H.4
Balagtas, C.C.5
Cheng, S.-L.6
Gelfand, R.A.7
-
53
-
-
0346967486
-
TECHNOS-PHERES™ for pulmonary and nasal applications. Respiratory
-
May 12-16
-
Wilson, B.R., Grant, M.L., Steiner, S.S., Pohl, R. TECHNOS-PHERES™ for pulmonary and nasal applications. Respiratory. Drug Del. VIII May 12-16 (2002).
-
(2002)
Drug Del.
, vol.8
-
-
Wilson, B.R.1
Grant, M.L.2
Steiner, S.S.3
Pohl, R.4
-
54
-
-
0033493161
-
Sustained release of insulin from insoluble inhaled particles
-
Vanbever, R., Ben-Jebria, A., Mintzes, J.D., Langer, R., Edwards, D.A. Sustained release of insulin from insoluble inhaled particles. Drug Dev. Res. 48, 178-185 (1999).
-
(1999)
Drug Dev. Res.
, vol.48
, pp. 178-185
-
-
Vanbever, R.1
Ben-Jebria, A.2
Mintzes, J.D.3
Langer, R.4
Edwards, D.A.5
-
55
-
-
0033925098
-
Sustained release drug delivery to the lungs
-
Hardy, J.G., Chadwick, T.S. Sustained release drug delivery to the lungs. Clin. Pharmacokinet. 39, 1-4 (2000).
-
(2000)
Clin. Pharmacokinet.
, vol.39
, pp. 1-4
-
-
Hardy, J.G.1
Chadwick, T.S.2
-
56
-
-
0028657017
-
Enzymatic barriers for GI peptide and protein delivery
-
Woodley, J.F. Enzymatic barriers for GI peptide and protein delivery. Crit. Rev. Ther. Drug Carrier Syst. 11, 61-95 (1994).
-
(1994)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.11
, pp. 61-95
-
-
Woodley, J.F.1
-
57
-
-
0031791711
-
Novel approaches for oral delivery of macromolecules
-
Fasano, A. Novel approaches for oral delivery of macromolecules. J. Pharm. Sci. 87, 1351-1356 (1998).
-
(1998)
J. Pharm. Sci.
, vol.87
, pp. 1351-1356
-
-
Fasano, A.1
-
58
-
-
0035498328
-
Peroral route: An opportunity for protein and peptide drug delivery
-
Sood, A., Panchagnula, R. Peroral route: an opportunity for protein and peptide drug delivery. Chem. Rev. 101, 3275-3303 (2001).
-
(2001)
Chem. Rev.
, vol.101
, pp. 3275-3303
-
-
Sood, A.1
Panchagnula, R.2
-
59
-
-
0036779424
-
Protein drug oral delivery: The recent progress
-
Lee, H.J. Protein drug oral delivery: the recent progress. Arch. Pharm. Res. 25, 572-584 (2002).
-
(2002)
Arch. Pharm. Res.
, vol.25
, pp. 572-584
-
-
Lee, H.J.1
-
60
-
-
0036391194
-
Oral delivery of proteins: Progress and prognostication
-
Shah, R.B., Ahsan, F., Khan, M.A. Oral delivery of proteins: progress and prognostication. Crit. Rev. Ther. Drug Carrier Syst. 19, 135-169 (2002).
-
(2002)
Crit. Rev. Ther. Drug Carrier Syst.
, vol.19
, pp. 135-169
-
-
Shah, R.B.1
Ahsan, F.2
Khan, M.A.3
-
61
-
-
0037393955
-
Challenges for the oral delivery of macromolecules
-
Goldberg, M., Gomez-Orellana, I. Challenges for the oral delivery of macromolecules. Nature Rev. 2, 289-295 (2003).
-
(2003)
Nature Rev.
, vol.2
, pp. 289-295
-
-
Goldberg, M.1
Gomez-Orellana, I.2
-
63
-
-
0033995073
-
Nanosphere based oral insulin delivery
-
Carino, G.P., Jacob, J.S., Mathiowitz, E. Nanosphere based oral insulin delivery. J. Control. Rel. 65, 261-269 (2000).
-
(2000)
J. Control. Rel.
, vol.65
, pp. 261-269
-
-
Carino, G.P.1
Jacob, J.S.2
Mathiowitz, E.3
-
65
-
-
0141830659
-
Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics
-
Allémann, E., Leroux, J.-C., Gurney, R. Polymeric nano- and microparticles for the oral delivery of peptides and peptidomimetics. Adv. Drug Del. Rev. 34, 171-189 (1998).
-
(1998)
Adv. Drug Del. Rev.
, vol.34
, pp. 171-189
-
-
Allémann, E.1
Leroux, J.-C.2
Gurney, R.3
-
66
-
-
0032853619
-
Intestinal peptide transport systems and oral drug availability
-
Yang, C.Y., Dantzig, A.H., Pidgeon, C. Intestinal peptide transport systems and oral drug availability. Pharm. Res. 16, 1331-1343 (1999).
-
(1999)
Pharm. Res.
, vol.16
, pp. 1331-1343
-
-
Yang, C.Y.1
Dantzig, A.H.2
Pidgeon, C.3
-
67
-
-
0034091858
-
The development of delivery agents that facilitate the oral absorption of macromolecular drugs
-
Leone-Bay, A., Paton, D.R., Weidner, J.J. The development of delivery agents that facilitate the oral absorption of macromolecular drugs. Med. Res. Rev. 20, 169-186 (2000).
-
(2000)
Med. Res. Rev.
, vol.20
, pp. 169-186
-
-
Leone-Bay, A.1
Paton, D.R.2
Weidner, J.J.3
-
68
-
-
0030446611
-
Oral delivery of rhGH: Preliminary mechanistic considerations
-
Leone-Bay, A., Leipold, H., Paton, D.R., Milstein, S.J., Baughman, R.A. Oral delivery of rhGH: preliminary mechanistic considerations. DN&P 9, 586-591 (1996).
-
(1996)
DN&P
, vol.9
, pp. 586-591
-
-
Leone-Bay, A.1
Leipold, H.2
Paton, D.R.3
Milstein, S.J.4
Baughman, R.A.5
-
69
-
-
0032580536
-
Partially unfolded proteins efficiently penetrate cell membranes - Implications for oral drug delivery
-
Milstein, S.J., Leipold, H., Sarubbi, D., Leone-Bay, A., Mlynek, G.M., Robinson, J.R., Kasimova, M., Freire, E. Partially unfolded proteins efficiently penetrate cell membranes - implications for oral drug delivery. J. Control. Rel. 53, 259-267 (1998).
-
(1998)
J. Control. Rel.
, vol.53
, pp. 259-267
-
-
Milstein, S.J.1
Leipold, H.2
Sarubbi, D.3
Leone-Bay, A.4
Mlynek, G.M.5
Robinson, J.R.6
Kasimova, M.7
Freire, E.8
-
70
-
-
0036676004
-
Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers
-
Buclin, T., Rochat, M.C., Burckhardt, P., Azria, M., Attinger, M. Bioavailability and biological efficacy of a new oral formulation of salmon calcitonin in healthy volunteers. J. Bone Mineral Res. 17, 1478-1485 (2002).
-
(2002)
J. Bone Mineral Res.
, vol.17
, pp. 1478-1485
-
-
Buclin, T.1
Rochat, M.C.2
Burckhardt, P.3
Azria, M.4
Attinger, M.5
-
71
-
-
0034865283
-
Oral delivery of biologically active parathyroid hormone
-
Leone-Bay, A., Sato, M., Paton, D., Hunt, A.H., Sarubbi, D., Carozza, M., Chou, J., McDonough, J., Baughman, R.A. Oral delivery of biologically active parathyroid hormone. Pharm. Res. 18, 964-970 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 964-970
-
-
Leone-Bay, A.1
Sato, M.2
Paton, D.3
Hunt, A.H.4
Sarubbi, D.5
Carozza, M.6
Chou, J.7
McDonough, J.8
Baughman, R.A.9
-
72
-
-
0036105205
-
Development of oral insulin: Progress and current status
-
Still, J.G. Development of oral insulin: progress and current status. Diabetes Metab. Res. Rev. 18, S29-S37 (2002).
-
(2002)
Diabetes Metab. Res. Rev.
, vol.18
-
-
Still, J.G.1
-
73
-
-
0036379293
-
Oral insulin product hexyl-insulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: The glucose stabilization effects of HIM2
-
Clement, S., Still, J.G., Kosutic, G., McAllister R.G. Oral insulin product hexyl-insulin monoconjugate 2 (HIM2) in type 1 diabetes mellitus: the glucose stabilization effects of HIM2. Diabetes Tech. Therapeut. 4, 459-466 (2002).
-
(2002)
Diabetes Tech. Therapeut.
, vol.4
, pp. 459-466
-
-
Clement, S.1
Still, J.G.2
Kosutic, G.3
McAllister, R.G.4
-
74
-
-
0038390434
-
Control of postprandial plasma glucose by an oral insulin product (HIM2) inpatients with type 2 diabetes
-
Kipnes, M., Dandona, P., Tripathy, D., Still, J.G., Kosutic, G. Control of postprandial plasma glucose by an oral insulin product (HIM2) inpatients with type 2 diabetes. Diabetes Care 26, 421-426 (2003).
-
(2003)
Diabetes Care
, vol.26
, pp. 421-426
-
-
Kipnes, M.1
Dandona, P.2
Tripathy, D.3
Still, J.G.4
Kosutic, G.5
-
75
-
-
0041319394
-
Emerging research opportunities in oral inhalation technology
-
Rios, M. Emerging research opportunities in oral inhalation technology. Pharm. Tech. 27, 42-49 (2003).
-
(2003)
Pharm. Tech.
, vol.27
, pp. 42-49
-
-
Rios, M.1
|