Synthesis and pharmacological assessment of derivatives of isoxazolo[4,5-d]pyrimidine

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 1, 2004, Pages 265-272

  Wagner, Edwin ^a   Becan, Lilianna ^a   Nowakowska, Elzbieta ^b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Anxiety; Anxiolytic compounds; Benzodiazepine receptors; Isoxazolo 4,5 d pyrimidinones

Indexed keywords

4 (4 CHLOROBENZOYLAMINO) 3 OXOISOXAZOLIDINE 5 CARBOXYLIC ACID AMIDE; 5 (2 HYDROXYPHENYL)TETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 (4 CHLOROPHENYL) 3A,7A DIHYDRO 6H ISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 (4 CHLOROPHENYL) 6H ISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 (4 CHLOROPHENYL)TETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 (4 FLUOROPHENYL)TETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 (4 METHOXYPHENYL)TETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 (4 NITROPHENYL)TETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 ETHYLTETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; 5 PHENYLTETRAHYDROISOXAZOLO[4,5 D]PYRIMIDINE 3,7 DIONE; ANXIOLYTIC AGENT; DIAZEPAM; FLUMAZENIL; ISOXAZOLIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; DRUG SYNTHESIS; MALE; NONHUMAN; RAT; TRANQUILIZING ACTIVITY;

EID: 0347301779     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2003.10.004     Document Type: Article

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