The Crystal Structure of Gankyrin, an Oncoprotein Found in Complexes with Cyclin-dependent Kinase 4, a 19 S Proteasomal ATPase Regulator, and the Tumor Suppressors Rb and p53

Journal of Biological Chemistry

Volumn 279, Issue 2, 2004, Pages 1541-1545

  Krzywda, Szymon ^a   Brzozowski, Andrzej M ^a   Higashitsuji, Hiroaki ^c   Fujita, Jun ^c   Welchman, Rebecca ^b   Dawson, Simon ^b   Mayer, R John ^b   Wilkinson, Anthony J ^a  

^a UNIVERSITY OF YORK   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CRYSTAL STRUCTURE; DEGRADATION; ENZYMES; TUMORS;

CELL CYCLES;

BIOCHEMISTRY;

ADENOSINE TRIPHOSPHATASE; CYCLIN DEPENDENT KINASE 4; GANKYRIN; ONCOPROTEIN; PROTEASOME; PROTEIN P53; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE NEDD4; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA REPAIR; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIVER CARCINOMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CELL LINE, TUMOR; CRYSTALLOGRAPHY, X-RAY; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASES; CYSTEINE ENDOPEPTIDASES; ELECTRONS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; ONCOGENE PROTEINS; PEPTIDE HYDROLASES; PEPTIDES; PLASMIDS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTO-ONCOGENE PROTEINS; RETINOBLASTOMA PROTEIN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0347093301     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M310265200     Document Type: Article

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