Acute cutaneous barrier disruption activates epidermal p44/42 and p38 mitogen-activated protein kinases in human and hairless guinea pig skin

Experimental Dermatology

Volumn 12, Issue 6, 2003, Pages 734-746

  Kobayashi, Hiromi ^a   Aiba, Setsuya ^a   Yoshino, Yumiko ^a   Tagami, Hachiro ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Barrier disruption; Mitogen activated protein kinase (MAPK); p38 MAPK; p44 42 MAPK; Tape stripping; TNF ; Transepidermal water loss

Indexed keywords

BETA ACTIN; CALCIUM; ION; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; ORGANIC SOLVENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; POTASSIUM; PROTEIN P42; PROTEIN P44; PROTEIN SERINE THREONINE KINASE; SPHINGOMYELIN PHOSPHODIESTERASE; STRESS ACTIVATED PROTEIN KINASE; SUCROSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CORRELATION ANALYSIS; ENZYME ACTIVATION; EPIDERMIS; GUINEA PIG; HAIR; HOMEOSTASIS; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MALE; NONHUMAN; NORMAL HUMAN; PERMEABILITY BARRIER; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKIN; SKIN DEFECT; VOLUNTEER; WATER LOSS; WESTERN BLOTTING;

ADULT; ANIMALS; BLOTTING, WESTERN; CALCIUM; EPITOPES; GUINEA PIGS; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POTASSIUM; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; SKIN; SKIN PHYSIOLOGY; TIME FACTORS; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0346969838     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0906-6705.2003.00045.x     Document Type: Article

References (56)

1. Hachem J, De Paepe K, Vanpee E, Kaufman L, Rogiers V, Rosseuw D. Combination therapy improves the recovery of the skin barrier function: An experimental model using a contact allergy patch test combined with TEWL measurements. Dermatology 2001: 202: 314-319.
2. Held E, Lund H, Agner T. Effect of different moisturizers on SLS-irritated human skin. Contact Dermatitis 2001: 44: 229-234.
3. Agner T. Nonivasive measuring methods for the investigation of irritant patch test reactions. A study of patients with hand eczema, atopic dermatitis and controls. Acta Dermato Venereol Suppl (Stockh) 1992: 173: 1-26.
4. Suetake T, Sasai S, Zhen Y, Ohi T, Tagami H. Functional analyses of the stratum corneum in scars. Sequential studies after injury and comparison among keloids, hypertrophic scars, and atrophic scars. Arch Dermatol 1996: 132: 1453-1458.
5. Berardesca E, Fideli D, Borroni G, Rabbiosi G, Maibach H. In vivo hydration and water-retention capacity of stratum corneum in clinically uninvolved skin in atopic and psoriatic patients. Acta Dermato Venereol 1990: 70: 400-404.
6. Loden M, Olsson H, Axell T, Linde Y W. Friction, capacitance and transepidermal water loss (TEWL) in dry atopic and normal skin. Br J Dermatol 1992: 126: 137-141.
7. Watanabe M, Tagami H, Horii I, Takahashi M, Kligman A M. Functional analyses of the superficial stratum corneum in atopic xerosis. Arch Dermatol 1991: 127: 1689-1692.
8. Werner Y, Lindberg M. Transepidermal water loss in dry and clinically normal skin in patients with atopic dermatitis. Acta Dermato-Venereologica 1985: 65: 102-105.
9. Ghadially R, Reed J T, Elias P M. Stratum corneum structure and function correlates with phenotype in psoriasis. J Invest Dermatol 1996: 107: 558-564.
10. Tagami H, Yoshikuni K. Interrelationship between water barrier and reservoir functions of pathologic stratum corneum. Arch Dermatol 1985: 121: 642-645.
11. Harris I R, Farrell A M, Grunfeld C, Holleran W M, Elias P M, Feingold K R. Permeability barrier disruption coordinately regulates mRNA levels for key enzymes of cholesterol, fatty acid, and ceramide synthesis in the epidermis. J Invest Dermatol 1997: 109: 783-787.
12. Holleran W M, Feingold K R, Man M Q, Gao W N, Lee J M, Elias P M. Regulation of epidermal sphingolipid synthesis by permeability barrier function. J Lipid Res 1991: 32: 1151-1158.
13. Menon G K, Feingold K R, Elias P M. Lamellar body secretory response to barrier disruption. J Invest Dermatol 1992: 98: 279-289.
14. Menon G K, Feingold K R, Moser Ah, Brown B E, Elias P M. De novo sterologenesis in the skin. II. Regulation by cutaneous barrier requirements. J Lipid Res 1985: 26: 418-427.
15. Ekanayake-Mudiyanselage S, Aschauer H, Schmook F P, Jensen J M, Meingassner J G, Proksch E. Expression of epidermal keratins and the cornified envelope protein involucrin is influenced by permeability barrier disruption. J Invest Dermatol 1998: 111: 517-523.
16. Denda M, Sato J, Tsuchiya T, Elias P M, Feingold K R. Low humidity stimulates epidermal DNA synthesis and amplifies the hyperproliferative response to barrier disruption: Implication for seasonal exacerbations for inflammatory dermatoses. J Invest Dermatol 1998: 111: 873-878.
17. Nickoloff B J & Naidu Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 1994: 30: 535-546.
18. Wood L C, Elias P M, Calhoun C, Tsai J C, Grunfeld C, Feingold K R. Barrier disruption stimulates interleukin-1 alpha expression and release from a pre-formed pool in murine epidermis. J Invest Dermatol 1996: 106: 397-403.
19. Wood L C, Jackson S M, Elias P M, Grunfeld C, Feingold K R. Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest 1992: 90: 482-487.
20. Wood L C, Stalder A K, Liou A, et al. Barrier disruption increases gene expression of cytokines and the 55 kD TNF receptor in murine skin. Exp Dermatol 1997: 6: 98-104.
21. Hardardottir I, Grunfeld C, Feingold K R. Effects of endotoxin and cytokines on lipid metabolism. Current Opinion Lipidol 1994: 5: 207-215.
22. Luger T A, Schwarz T. Evidence for an epidermal cytokine network. [Review]. J Invest Dermatol 1990: 95: 100S-104S.
23. Ristow H J. A major factor contributing to epidermal proliferation in inflammatory skin diseases appears to be interleukin 1 or a related protein. Proc Natl Acad Sci U S A 1987: 84: 1940-1944.
24. Man M Q, Wood L, Elias P M, Feingold K R. Cutaneous barrier repair and pathophysiology following barrier disruption in IL-1 and TNF type I receptor deficient mice. Exp Dermatol 1998: 8: 261-266.
25. Jensen J M, Schutze S, Forl M, Kronke M, Proksch E. Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier. J Clin Invest 1999: 104: 1761-1770.
26. Kreder D, Krut O, Adam-Klages S, et al. Impaired neutral sphingomyelinase activation and cutaneous barrier repair in FAN-deficient mice. EMBO J 1999: 18: 2472-2479.
27. + gradients in murine epidermis: Quantitative measurement using PIXE. J Invest Dermatol 1998: 111: 1198-1201.
28. Sturgill T W, Ray L B, Erikson E, Maller J L. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II. Nature 1988: 334: 715-718.
29. Marshall C J. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation. Cell 1995: 80: 179-185.
30. Lee J C, Laydon J T, McDonnell P, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994: 372: 739-746.
31. Xia Z, Dickens M, Raingeaud J, Davis R J, Greenberg M E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995: 270: 1326-1331.
32. Berl T, Siriwardana G, Ao L, Butterfield L M, Heasley L E. Multiple mitogen-activated protein kinases are regulated by hyperosmolality in mouse IMCD cells. Am J Physiol 1997: 272: F305-F311.
33. Galcheva-Gargova Z, Derijard B, Wu I H, Davis R J. An osmosensing signal transduction pathway in mammalian cells. Science 1994: 265: 806-808.
34. Itoh T, Yamauchi A, Miyai A, et al. Mitogen-activated protein kinase and its activator are regulated by hypertonic stress in Madin-Darby canine kidney cells. J Clin Invest 1994: 93: 2387-2392.
35. Rosette C, Karin M. Ultraviolet light and osmotic stress. Activation of the JNK cascade multiple growth factor and cytokine receptors. Science 1996: 274: 1194-1197.
36. Terada Y, Tomita K, Homma M K, et al. Sequential activation of Raf-1 kinase, mitogen-activated protein (MAP) kinase kinase, MAP kinase, and S6 kinase by hyperosmolality in renal cells. J Biol Chem 1994: 269: 31296-31301.
37. Zhang Z, Cohen D M. NaCl but not urea activates p38 and jun kinase in mIMCD3 murine inner medullary cells. Am J Physiol 1996: 271: F1234-F1238.
38. Lee Sh, Elias P M, Proksch E, Menon G K, Mao Quiang M, Feingold K R. Calcium and potassium are important regulators of barrier homeostasis in murine epidermis. J Clin Invest 1992: 89: 530-538.
39. Menon G K, Elias P M. Ultrastructural localization of calcium in psoriatic and normal human epidermis. Arch Dermatol 1991: 127: 57-63.
40. Menon G K, Grayson S, Elias P M. Ionic calcium reservoirs in mammalian epidermis: Ultrastructural localization by ion-capture cytochemistry. J Invest Dermatol 1985: 84: 508-512.
41. Mao-Qiang M, Mauro T, Bench G, Warren R, Elias P M, Feingold K R. Calcium and potassium inhibit barrier recovery after disruption, independent of the type of insult in hairless mice. Exp Dermatol 1997: 6: 36-40.
42. Menon G K, Elias P M, Lee S H, Feingold K R. Localization of calcium in murine epidermis following disruption and repair of the permeability barrier. Cell Tissue Res 1992; 270: 503-512.
43. Medema J P, Sark M W, Backendorf C, Bos J L. Calcium inhibits epidermal growth factor-induced activation of p21ras in human primary keratinocytes. Mol Cellular Biol 1994: 14: 7078-7085.
44. Dong Z, Qi X, Fidler I J. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. J Exp Med 1993: 177: 1071-1077.
45. Hambleton J, McMahon M, DeFranco A L. Activation of Raf-1 and mitogen-activated protein kinase in murine macrophages partially mimics lipopolysaccharide-induced signaling events. J Exp Med 1995: 182: 147-154.
46. Liu M K, Herrera-Velit P, Brownsey R W, Reiner N E. CD14-dependent activation of protein kinase C and mitogen-activated protein kinases (p42 and p44) in human monocytes treated with bacterial lipopolysaccharide. J Immunol 1994: 153: 2642-2652.
47. Reimann T, Buscher D, Hipskind R A, Krautwald S, Lohmann-Matthes M L, Baccarini M. Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes. J Immunol 1994: 153: 5740-5749.
48. Swantek J L, Cobb M H, Geppert T D. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-alpha) translation: Glucocorticoids inhibit TNF-alpha translation by blocking JNK/SAPK. Mol Cellular Biol 1997: 17: 6274-6282.
49. Bhat N R, Zhang P, Lee J C, Hogan E L. Extracellular signal-regulated kinase and p38 subgroups of mitogen-activated protein kinases regulate inducible nitric oxide synthase and tumor necrosis factor-alpha gene expression in endotoxin-stimulated primary glial cultures. J Neuroscience 1998: 18: 1633-1641.
50. Chan E D, Winston B W, Uh S T, Wynes M W, Rose D M, Riches D W. Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages. J Immunol 1999: 162: 415-422.
51. Rafiee P, Lee J K, Leung C C, Raffin T A. TNF-alpha induces tyrosine phosphorylation of mitogen-activated protein kinase in adherent human neutrophils. J Immunol 1995: 154: 4785-4792.
52. Raines M A, Kolesnick R N, Golde D W. Sphingo-myelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells. J Biol Chem 1993: 268: 14572-14575.
53. Vietor I, Schwenger P, Li W, Schlessinger J, Vilcek J. Tumor necrosis factor-induced activation and increased tyrosine phosphorylation of mitogen-activated protein (MAP) kinase in human fibroblasts. J Biol Chem 1993: 268: 18994-18999.
54. Winston B W, Chan E D, Johnson G L, Riches D W. Activation of p38mapk, MKK3, and MKK4 by TNF-alpha in mouse bone marrow-derived macrophages. J Immunol 1997: 159: 4491-4497.
55. Winston B W, Lange-Carter C A, Gardner A M, Johnson G L, Riches D W. Tumor necrosis factor alpha rapidly activates the mitogen-activated protein kinase (MAPK) cascade in a MAPK kinase kinase-dependent, c-Raf-1-independent fashion in mouse macrophages. Proc Natl Acad Sci U S A 1995: 92: 1614-1618.
56. Haase I, Hobbs R M, Romero M R, Broad S, Watt F M. A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis. J Clin Invest 2001: 108: 527-536.