Expression of epidermal keratins and the cornified envelope protein involucrin is influenced by permeability barrier disruption

Journal of Investigative Dermatology

Volumn 111, Issue 3, 1998, Pages 517-523

  Ekanayake Mudiyanselage, Swarna ^a   Aschauer, Heinrich ^b   Schmook, Fritz P ^b   Jensen, Jens Michael ^a   Meingassner, Josef G ^b   Proksch, Ehrhardt ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b NOVARTIS RESEARCH INSTITUTE   (Austria)

Author keywords

Loricrin

Indexed keywords

ACETONE; DODECYL SULFATE SODIUM; ENVELOPE PROTEIN; INVOLUCRIN; KERATIN; KERATIN ANTIBODY; LORICRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA SYNTHESIS; EPIDERMIS; ESSENTIAL FATTY ACID DEFICIENCY; FEMALE; KERATINOCYTE; MOUSE; NONHUMAN; NUDE MOUSE; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SKIN BIOPSY; SKIN PERMEABILITY;

EID: 0031687883     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00318.x     Document Type: Article

References (56)

1. R), cyclosporin H and FK506. Exp Dermatol 1:199-205, 1992
2. Bickenbach JR, Greer JM, Bundman DS, Rothnagel JA, Roop DK: Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development. J Invest Dermatol 104:405-410, 1995
3. Cheng J, Syder AJ, Yu QC, Letai A, Paller AS, Fuchs E: The genetic basis of epidermolytic hyperkeratosis: a disorder of differentiation-specific epidermal keratin genes. Cell 70:811-819, 1992
4. Chipev CC, Korge BP, Markova N, Bale SJ, DiGiovanna JJ, Compton JG, Steinert PM: A leucine-proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis. Cell 70:821-828, 1992
5. Choi JS, Jackson SM, Elias PM, Feingold KR: The role of protein synthesis in permeability barrier homeostasis. In: Ohkawa A, McGuire J (eds). The Biology of the Epidermis. Amsterdam: Elsivier Science, 1992, pp. 11-19
6. Downing DT: Lipid and protein structures in the permeability barrier of mammalian epidermis. J Lipid Res 33:301-313, 1992
7. Elias PM: Epidermal lipids, barrier function, and desquamation. J Invest Dermatol 80:44-49, 1983
8. Frost P, Weinstein GD, Bothwell JW, Wildnauer R: Ichthyosiform dermatoses: III. studies of transepidermal water loss. Arch Dermatol 98:230-233, 1968
9. Fuchs E: Keratins and the skin. Annu Rev Cell Dev Biol 11:123-155, 1995
10. Grubauer G, Feingold KR, Elias PM: The relationship of epidermal lipogenesis. J Lipid Res 28:746-752, 1987
11. Grubauer G, Elias PM, Feingold KR: Transepidermal water loss: the signal for recovery of barrier structure and function. J Lipid Res 30:323-333, 1989
12. Hagemann I, Proksch E: Topical treatment by urea reduces epidermal hyperproliferation and induces differentiation in psoriasis. Acta Derm Venereol (Stockh) 76:353-6, 1996
13. Hazelbag HM, van der Broek LJCM, van Dorst EBL, Offerhaus GJA, Fleuren GJ, Hogendoorn PCW: Immunostaining of chain-specific keratins on formalin-fixed, paraffin-embedded tissues: A comparison of various antigen retrieval systems using microwave heating and proteolytic pre-treatments. J Histochem Cytochem 43:429-437, 1995
14. Hohl D: Cornified cell envelope. Dermatologica 180-201, 1990
15. Hohl D: Expression patterns of loricrin in dermatological disorders. Am J Dermatopath 15:20-27, 1993
16. Hohl D, Olano RB, de Viragh PA, Huber M, Detrisac CJ, Schnyder UW, Roop DR: Expression patterns of loricrin in various species and tissues. Differentiation 54:25-34, 1993
17. Holleran WM, Feingold KR, Mao-Qiang M, Gao WN, Lee JM, Elias PM: Regulation of epidermal sphingolipid synthesis by permeability barrier function. J Lipid Res 32:1151-1158, 1991
18. Hou SYE, Mitra AK, White SH, Menon GK, Ghadially R, Elias PM: Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction. J Invest Dermatol 96:215-223, 1991
19. Jackson SM, Word LC, Luner S, Taylor JM, Cooper AD, Elias PM, Feingold KR: Effect of cutaneous permeability barrier disruption on HMG-CoA reductase, LDL receptor, and apolipoprotein E mRNA levels in the epidermis of hairless mice. J Lipid Res 33:1307-1314, 1992
20. Jiang CK, Magnaldo T, Ohtsuki M, Freedberg IM, Bernerd F, Blumenberg M: Epidermal growth factor and transforming growth factor α specifically induce the activation-and hyperproliferation-associated keratins 6 and 16. Proc Natl Acad Sci USA 90:6786-6790, 1993
21. Kanitakis J, Zambruno G, Viac J, Thivolet J: Involucrin expression in keratinization disorders of the skin - a preliminary study. Br J Dermatol 117:479-480, 1987
22. Kopan R, Fuchs E: The use of retinoic acid to probe the relation between hyperproliferation - associated keratins and cell proliferation in normal and malignant epidermal cells. J Cell Biol 109:295-307, 1989
23. Laemmli UK: Cleavage of structural proteins during the assembly of the head of Bacteriophage T4. Nature 227:680-685, 1970
24. Lane EB, Rugg EL, Navasaria H, Leigh IM, Heagerty AHM, Ishida-Yamamoto A, Eady RAJ: A mutation in the conserved helix termination peptide of Keratin 5 in hereditary skin blistering. Nature 356:244-246, 1992
25. Le TKM, van der Valk PGM, Schalkwijk J, van de Kerkhof PCM: Changes in epidermal proliferation and differentiation in allergic and irritant contact dermatitis reactions. Br J Dermatol 133:236-240, 1995
26. Leigh IM, Navsaria H, Purkis PE, McKay IA, Bowden PE, Riddle PN: Keratins (K16 and K17) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro. Br J Dermatol 133:501-511, 1995
27. Mansbridge JN, Knapp AM: Changes in keratinocyte maturation during wound healing. J Invest Dermatol 89:253-263, 1987
28. McKay IA, Leigh IM: Altered keratinocyte growth and differentiation in psoriasis. Clinics Dermatol 13:105-114, 1995
29. Menon GK, Feingold KR, Elias PM: Lamellar body secretory response to barrier disruption. J Invest Dermatol 98:279-289, 1992
30. Ming ME, Daryanani HA, Roberts LP, Baden HP, Kvedar JC: Binding of keratin intermediate filaments (K10) to the cornified envelope in mouse epidermis: implications for barrier function. J Invest Dermatol 103:780-784, 1994
31. Moll I: Cytokeratine. Hautarzt 44:491-500, 1993
32. O'Farell PZ, Goodman HM, O'Farell PH: High resolution two-dimensional electrophoresis of basic as wells as acid proteins. Cell 12:1133-1142, 1977
33. Ottey KA, Wood LC, Grunfeld C, Elias PM, Feingold KR: Cutaneous permeability barrier disruption increases fatty acid synthetic enzyme activity in the epidermis of hairless mice. J Invest Dermatol 104:401-404, 1995
34. Paladini RD, Takahashi K, Bravo NS, Coulombe PA: Onset of reepithelization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16. J Cell Biol 381-397, 1996
35. Proksch E, Hagemann I: Topical treatment by urea reduces epidermal hyperproliferation and induces differentiation in psoriasis. Acta Derm Venereol (Stockh) 76:353-356, 1996
36. Proksch E, Elias PM, Feingold KR: Regulation of 3-hydroxy-3-methylglutaryl- coenzyme a reductase activity in murine epidermis. J Clin Invest 85:874-882, 1990
37. Proksch E, Feingold KR, Elias PM: Barrier function regulates epidermal DNA- synthesis. J Clin Invest 87:1668-1673, 1991
38. Proksch E, Feingold KR, Elias PM: Epidermal HMG CoA reductase activity in essential fatty acid deficiency: barrier requirements rather than eicosanoid generation regulate cholesterol synthesis. J Invest Dermatol 99:216-220, 1992
39. Proksch E, Brasch J, Sterry W: Integrity of the permeability barrier regulates epidermal Langerhans cell density. Br J Dermatol 134:630-638, 1996
40. Rice RH, Green H: Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. Cell 18:681-694, 1979
41. Robinson NA, Latell PT, Eckert RL: Involucrin is a covalently cross-linked consistent of highly purified epidermal corneocytes: evidence for a common pattern of involucrin cross-linked in vivo and in vitro. J Invest Dermatol 107:101-107, 1996
42. Roop D: Defects in the barrier. Science 267:474-476, 1995
43. Rosenthal DS, Griffiths CEM, Yuspa SH, Roop DR, Voorhees JJ: Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin and keratins 6 and 13 but not keratins 1, 10, and 14. J Invest Dermatol 98:343-349, 1992
44. Rothnagel JA, Dominey AM, Dempsey LD, et al: Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis. Science 257:1128-1130, 1992
45. Schweizer J: Murine epidermal keratins. In: Darmon M, Blumenberg M (eds). Molecular Biology of the Skin: The Keratinocyte. San Diego: Academic Press, 1993, pp. 33-78
46. Smack PD, Korge BP, James WD: Keratin and keratinization. J Am Acad Dermatol 30:85-102, 1994
47. Steinert PM, Marekov LN: The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross- linked components of the human epidermal cornified cell envelope. J Biol Chem 270:17702-17711, 1995
48. Steinert PM, Marekov LN: Direct evidence that involucrin is a major early isopeptide cross-linked of the keratinocyte cornified cell envelope. J Biol Chem 272:2021-2030, 1997
49. Thewes M, Stadler R, Korge B, Mischke D: Normal psoriatic epidermis expression of hyperproliferation-associated keratins. Arch Dermatol Res 283:465-471, 1991
50. Welzel J, Wilhelm KP, Wolff HH: Skin permeability barrier and occlusion: no delay of repair in irritated human skin. Contact Dermatitis 35:163-168, 1996
51. Wertz PW, Swartzendruber DC, Abraham WH, Madison KL, Downing DT: Essential fatty acids and epidermal integrity. Arch Dermatol 123:1381-1384, 1987
52. Wertz PW, Madison KC, Downing DT: Covalently bound lipids of human stratum corneum. J Invest Dermatol 92:109-111, 1989
53. Wild G, Mischke D: Variation and frequency of cytokeratine polypeptide patterns in human squamous non-keratinizing epithelium. Exp Cell Res 102:114-126, 1986
54. Wilson AK, Coulombe PA, Fuchs E: The roles of K5 and K14 head tail and R/KLLEGE domains in keratin filament assembly in vitro. J Cell Biol 119:401-414, 1992
55. Yoshikawa K, Katagata Y, Kondo S: Relative amounts of keratin 17 are higher than those of keratin 16 in hair-follicle-derived tumors in comparison with nonfollicular epithelial skin tumors. J Invest Dermatol 104:396-400, 1995
56. Zouboulis CC, Korge BP, Mischke D, Orfanos CE: Altered proliferation, synthetic activity, and differentiation of cultured human sebocytes in the absence of vitamin A and their modulation by synthetic retinoids. J Invest Dermatol 101:628-633, 1993