Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains

Carcinogenesis

Volumn 24, Issue 12, 2003, Pages 1913-1918

  Zsivkovits, Markus ^a   Fekadu, Kassie ^a   Sontag, Gerhard ^b   Nabinger, Ursula ^a   Huber, Wolfgang W ^a   Kundi, Michael ^c   Chakraborty, Asima ^a   Foissy, Helmuth ^d   Knasmüller, Siegfried ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b Institute of Organic Chemistry   (Austria)

^c Institute of Environmental Hygiene   (Austria)

^d Agricultural University   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; HETEROCYCLIC AMINE; INDOLE DERIVATIVE; QUINOXALINE DERIVATIVE; YOGHURT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COUNT; BACTERIAL KINETICS; BACTERIAL STRAIN; BACTERIUM; BIFIDOBACTERIUM LONGUM; CELL PROTECTION; CHEMICAL ANALYSIS; CHICKEN; COLON; COLON CANCER; COMET ASSAY; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DNA TRANSPOSITION; FECES ANALYSIS; FEEDING; FOOD INDUSTRY; FOOD INTAKE; GENDER; GENOTOXICITY; IN VITRO STUDY; INTERMETHOD COMPARISON; INTESTINE CELL; LACTOBACILLUS; LACTOBACILLUS BULGARICUS; LIVER; LIVER CELL; MALE; MEAT; NONHUMAN; PREVENTION; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; STRAIN DIFFERENCE; STREPTOCOCCUS THERMOPHILUS; SUSPENSION; TIME;

AMINES; ANIMALS; COLON; COLONIC NEOPLASMS; COMET ASSAY; DNA; DNA DAMAGE; LACTIC ACID; LACTOBACILLUS; LIVER; LIVER EXTRACTS; LIVER NEOPLASMS; MALE; RATS; RATS, INBRED F344; TIME FACTORS;

EID: 0346888661     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgg167     Document Type: Article

References (51)

1. Augustsson,K. and Steineck,G. (2000) Cancer risk based on epidemiological studies, In Nagao,M. and Sugimura,T. (eds), Food Borne Carcinogenesis: Heterocyclic Amines. Wiley, New York, NY, pp. 332-347.
2. Sugimura,T., Nagao,M. and Wakabayashi,K. (2000) Complex factors pertinent to human hazard risks. In Nagao,M. and Sugimura,T. (eds), Food Borne Carcinogenesis: Heterocyclic Amines. Wiley, New York, NY, pp. 349-359.
3. Dashwood,L.H. (2002) Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters and transgenic models. Mutat. Res., 511, 89-112.
4. Schwab,C.E., Huber,W.W., Parzefall,W., Hietsch,G., Kassie,F., Schulte-Hermann,R. and Knasmüller,S. (2000) Search for compounds that inhibit the genotoxic and carcinogenic effects of heterocyclic aromatic amines. Crit. Rev. Toxicol., 30, 1-69.
5. Jacobs,D.R., Slavin,J. and Marquart,L. (1995) Whole grain intake and cancer: a review of the literature. Nutr. Cancer, 24, 221-229.
6. Steinmetz,K.A. and Potter,J.D. (1996) Vegetables, fruit and cancer prevention: a review. J. Am. Diet. Assoc., 96, 1027-1039.
7. Wollowski,I., Rechkemmer,G. and Pool-Zobel,B.L. (2001) Protective effects of probiotics and prebiotics in colon cancer. Am. J. Clin. Nutr., 73 (suppl.), 451S-455S.
8. Knasmüller,S., Steinkellner.,H, Majer,B.J., Nobis,E.C., Scharf,G. and Kassie,F. (2002) Search for dietary antimutagens and anticarcinogens: methodological aspects and extrapolation problems. Food Chem. Toxicol., 40, 1051-1062.
9. Zhang,X.B. and Ohta,Y. (1991) Binding of mutagens by fractions of the cell wall skeleton of lactic acid bacteria on mutagens. J. Dairy Sci., 74, 1477-1481.
10. Zhang,X.B. and Ohta,Y. (1993) Microorganisms in the gastrointestinal tract of the rat prevent absorption of the mutagen-carcinogen 3-amino-1, 4-dimethyl-5H-pyrido[4,3-b]indole. Can. J. Microbiol., 39, 841-845.
11. Reddy,B.S. and Rivenson A. (1993) Inhibitory effect of Bifidobacterium longum on colon, mammary and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline a food mutagen. Cancer Res., 53, 3914-3918.
12. Felton,J.S., Jägerstad,M., Knize,M.G., Skog,K. and Wakabayashi,K. (2000) Contents in foods, beverages and tobacco. Nagao,M. and Sugimura,T. (eds), Food Borne Carcinogenesis: Heterocyclic Amines. Wiley, New York, NY, pp. 5-29.
13. Tavan,E., Cayuela,C., Antoine,J.M., Trugnan,G., Chaugier,C. and Cassand,P. (2002) Effects of dairy products on heterocyclic aromatic amine-induced rat colon carcinogenesis. Carcinogenesis, 23, 477-483.
14. Orrhage,K.M., Annas,A., Nord,C.E., Brittebo,E.B. and Rafter,J.J. (2002) Effects of lactic acid bacteria on the uptake and distribution of the food mutagen Trp-P-2 in mice. Scand. J. Gastroenterol., 37, 215-221.
15. Keating,G.A. and Bogen,K.T. (2001) Methods for estimating heterocyclic amine concentrations in cooked meats in the US diet. Food Chem. Toxicol., 39, 29-43.
16. Ohgaki,H. (2000) Carcinogenicity in animals and specific organs, Rodents. In Nagao,M. and Sugimura,T. (eds), Food Borne Carcinogenesis: Heterocyclic Amines. Wiley, New York, NY, pp. 198-228.
17. Sekihashi,K., Yamamoto,A., Matsumura,Y., Ueno,S., Watanabe-Akanuma,M., Kassie,F., Knasmüller,S., Tsuda,S. and Sasaki,Y.F. (2002) Comparative investigation of multiple organs of mice and rats in the comet assay. Mutat. Res., 517, 53-75.
18. Kassie,F., Rabot,S., Uhl,M., Huber,W., Qin,H.M., Helma,C., Schulte-Hermann,R. and Knasmüller,S. (2002) Chemoprotective effect of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions. Carcinogenesis, 23, 1155-1161
19. Kassie,F., Uhl,M., Rabot,S., Grasl-Kraupp,B., Verkerk,R., Kundi,M., Chabicovsky,M., Schulte-Hermann,R. and Knasmüller,S. (2003) Chemoprevention of 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen. Carcinogenesis, 24, 255-261.
20. Uhl,M., Darroudi,F., Seybel,A., Steinkellner,H., Kassie,F., Grasl-Kraupp,B., Mersch-Sundermann,V. and Knasmüller,S. (2001) Development and use of new experimental models for the identification of DNA-protective and anticarcinogenic plant constituents. In Kreft,I. (ed.), Molecular and Genetic Interactions Involving Phytochemicals. COST-916 Action, Ljubljana, Slovenia, pp. 21-35.
21. Kassie,F., Mersch Sundermann,V., Edenharder,R. et al. (2003) Development and application of test methods for the detection of dietary constituents which protect against heterocyclic aromatic amines. Murat. Res., 523/524, 183-192.
22. Uhl,M. (2002) Einfluss von Inhaltsstoffen von Brassicacen auf DNA-schädigende und kanzerogene Effekte von heterozyklischen aromatischen Aminen. PhD thesis, University of Vienna.
23. Humblot,C., Kassie,F., Nugon-Baudon,L., Knasmüller,S. and Lhoste,E.F. (2003) Diet modulates the genotoxicity of IQ (2-amino-3-methylimidazo [4,5-f]quinoline) in rats associated with a human faecal flora. J. Chromatogr., in press.
24. Bast,E. (1999) Bestimmung der Zellzahl und Zellmasse einzelliger Mikroorganismen. In Bast,E. (ed.), Mikrobiologische Methoden: Eine Einführung in grundlegende Arbeitstechniken. Spektrum Akademischer Verlag, Heidelberg, Germany.
25. Gerten,B. (1993) Nährböden. In Gerten,B. (ed.), OXOID Handbuch 5. Aktualisierte Auflage. R. Meyer, Düsseldorf, Germany.
26. Kassie,F., Rabot,S., Kundi,M. Chabicovsky,M., Qin,H.-M. and Knasmüller,S. (2001) Intestinal flora plays a crucial role in the genotoxicity of the cooked food mutagen 2-amino-3-methylimidazo [4,5-f]quinoline (IQ). Carcinogenesis, 22, 1721-1725.
27. Bradley,M.O., Dysart,G., Fitzsimmons,D., Harbach,P., Lewin,J. and Wolf,G. (1982) Measurement by filter elution of DNA single and double strand breaks in rat hepatocytes: effects of nitrosamines and γ-irradiation. Cancer Res., 42, 2592-2597.
28. Brendler,S., Tompa,A., Hutter,K.H., Preussmann,R. and Pool-Zobel,B.L. (1992) In vivo and in vitro gentoxicity of several N-nitrosamines in extrahepatic tissues of the rat. Carcinogenesis, 13, 2535-2441.
29. Lindl,T. and Bauer,J. (1994) Zell und Gewebekultur: Einführung in die Grundlagen sowie ausgewählte Methoden und Anwendungen. Gustav Fischer Verlag, Stuttgart, Germany.
30. Tice,R.R., Agurell,E., Anderson,D. et al. (2000) Single cell gel/comet assay: guidlines for in vivo and in vitro genetic toxicology testing. Environ. Mol. Mutagen., 35, 206-221.
31. Helma,C. and Uhl,M. (2000) A public domain image analysis program for the single cell gel electrophoresis (comet) assay. Mutat. Res., 446, 9-15.
32. Wollowski,I., Ji,S.T., Bakalinsky,A.T., Neudecker,C. and Pool-Zobel,B.L. (2001) Bacteria used for the production of yoghurt inactivate carcinogens and prevent DNA-damage in the colon cells. J. Nutr., 129, 77-82.
33. Bolognani,F., Rummey,C.J., Pool-Zobel,B.L. and Rowland,I.R. (2001) Effect of lactobacilli, bifidobacteria and inulin on the formation of aberrant crypt foci in rats. Eur. J. Nutr., 40, 293-300.
34. Zisvkovits,M (2002) Der Einfluss von Milchsäurebakterien auf die Genotoxizität von heterozyklischen aromatischen Aminen (HCAs). Thesis, Vienna, Austria.
35. Kailasapathy,K. and Chin,J. (2000) Survival and therapeutic potential of probiotic organisms with reference to Lactobacillus acidophilus and Bifidobacterium spp. Immunol. Cell Biol., 78, 80-88.
36. Orrhage,K., Sillerström,E., Gustafsson,J.-A., Nord,C.E. and Rafter,J. (1994) Binding of mutagenic heterocyclic amines by intestinal and lactic acid bacteria. Mutat. Res., 311, 239-248.
37. Knasmüller,S., Steinkellner,H., Hirschl,M.A., Rabot,S., Nobis,E.C. and Kassie,F. (2001) Impact of bacteria in dairy products and of the intestinal microflora on the genotoxic and carcinogenic effects of heterocyclic amines. Mutat. Res., 480, 129-138.
38. Muscettola,M., Massi,L., Tanganelli,C. and Grasso,G. (1994) Effects of lactobacilli on interferon production in young and aged mice. Ann. N. Y. Acad. Sci., 717, 226-232.
39. Coconnier,M.H., Klaenhammer,T.R., Kemeis,S., Bernet,M.F. and Servin,A.L. (1992) Protein mediated adhesion of Lactobacillus acidophilus BG2FO4 on human enterocyte and mucus secreting cell lines in culture. Appl. Environ. Microbiol., 58, 2034-2039.
40. Bernet,M.F., Brassart,D., Nesser,J.R. and Servin,A.L (1994) Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria. Gut, 35, 483-489.
41. Gerbl,U., Cichna,M., Zsivkovits,M., Knasmüller,S. and Sontag,G. (2003) Determination of heterocylcic aromatic amines in beef extract, cooked meat and rat urine by HPLC with coulometric eleectrode array detection, J. Chromatogr., in press.
42. Hayatsu,H. and Hayatsu,T. (1993) Suppressing effect of Lactobacillus casei administration on the urinary mutagenicity arising from fried ground beef in the human. Cancer Lett., 73, 173-179.
43. Lidbeck,A., Övervik,E., Rafter,J., Nard,C.E. and Gustafsson,J.A. (1992) Effects of Lactobacillus acidophilus supplements on mutagen excretion in feces and urine of humans. Microbiol. Environ. Health, 5, 59-67.
44. Greene,J.D. and Klaenhammer,T.R. (1994) Factors involved in the adherence of lactobacilli to human Caco-2 cells. Appl. Environ. Microbiol., 60, 4487-4494.
45. Sreekumar,O. and Hsono,A. (1998) The heterocyclic amine binding receptors of Lactobacillus gasseri. Mutat. Res., 421, 65-72.
46. Humblot,C., Combourieu,B., Väisanen,M.-L. et al. (2003) Metabolism of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) by the human digestive flora and by bacteria isolated from it. In 2nd International Workshop on Heterocyclic Aromatic Amines (abstract), Graz, Austria.
47. Lamb,J.G. and Franklin,M.R. (2000) Early events in the induction of rat hepatic UDP-glucuronosyltransferases, glutathione S-transferase and microsomal epoxide hydrolase by 1,7-phenanthroline: comparison with oltipraz, tert-butylhydroxyanisole and tert-butylhydroquinone. Drug. Metab. Dispos., 28, 1018-1023.
48. Kim,S.G., Nam,S.Y., Kim,C.W., Kim,J.H., Cho,C.K. and Yoo,S.Y. (1997) Enhancement of radiation-inducible hepatic glutathione-S-transferases Ya,Yb1,Yc1 and Yc2 gene expression by oltipraz: possible role in chemoprotection. Mol. Pharmacol., 51, 225-233.
49. Cho,M.C. and Kim,S.G. (1998) Differential induction of rat hepatic microsomal epoxide hydrolase and rGSTA2 by diazines: the role of cytochrome P450 2E1-mediated metabolic activation. Chem. Biol. Interact., 116, 229-245.
50. Siess,M.-H., Mas,J.-P., Canivence-Lavier,M.-C. and Suschetet,M. (1996) Time course of induction of rat hepatic drug metabolising enzyme activities following dietary administration of flavonoids. J. Toxicol. Environ. Health, 49, 481-496.
51. Stillwell,W.G., Skipper,P.L. and Tannenbaum,S.R. (2002) Biomonitoring: methods and analysis, In Nagao,M. and Sugimura,T. (eds), Food Borne Carcinogenesis: Heterocyclic Amines. Wiley, New York, NY, pp. 319-331.