Presence of high levels of MT1-MMP protein in fibroblastic cells of human invasive carcinomas

International Journal of Cancer

Volumn 82, Issue 2, 1999, Pages 208-212

  Chenard, Marie Pierre ^a   Lutz, Yves ^b   Mechine Neuville, Agnés ^a   Stoll, Isabelle ^b   Bellocq, Jean Pierre ^a   Rio, Marie Christine ^b   Basset, Paul ^b  

^a HÔPITAL DE HAUTEPIERRE   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRIX METALLOPROTEINASE;

ARTICLE; CANCER GROWTH; CANCER INVASION; CARCINOMA; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES, MONOCLONAL; BREAST NEOPLASMS; CARCINOMA; CARCINOMA, DUCTAL, BREAST; CARCINOMA, LOBULAR; COS CELLS; ENZYME ACTIVATION; ENZYME INDUCTION; EPITOPES; FEMALE; FIBROBLASTS; HUMANS; IMMUNOENZYME TECHNIQUES; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASES, MEMBRANE-ASSOCIATED; METALLOENDOPEPTIDASES; MICE; MICE, INBRED BALB C; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; RECOMBINANT PROTEINS; STROMAL CELLS; TRANSFECTION;

EID: 0033052753     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19990719)82:2<208::AID-IJC10>3.0.CO;2-9     Document Type: Article

References (27)

1. ALI, S., LUTZ, Y., BELLOCQ, J.P., CHENARD, M.P., ROUYER, N. and METZGER, D., Production and characterization of monoclonal antibodies recognizing defined regions of the human oestrogen receptor. Hybridoma, 12, 391-405 (1993).
2. BASSET, P., OKADA, A., CHENARD, M.P., KANNAN, R., STOLL, I., ANGLARD, P., BELLOCQ, J.P. and RIO, M.C., Matrix metalloproteinases as stromal effectors of human carcinoma progression: therapeutical implications. Matrix Biol., 15, 534-541 (1997).
3. BROOKS, P., STRÖMBLAD, S., SANDERS, L.C., VON SCHALSCHA, T., AIMES, R., STETLER-STEVENSON, W., QUIGLEY, J. and CHERESH, D., Localization of matrix metalloproteinase MMP2 to the surface of invasive cells by interaction with integrin αvβ3. Cell, 85, 683-693 (1996).
4. BUTLER, G.S., BUTLER, M.J., ATKINSON, S.J., WILL, H., TAMURA, T., SCADE VAN WESTRUM, S., CRABBE, T., CLEMENTS, J., D'ORTHO, M.P. and MURPHY, G., The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. J. biol. Chem., 273, 871-880 (1998).
5. CAO, J., SATO, H., TAKINO, T. and SEIKI, M., The C-terminal region of membrane type matrix metalloproteinase is a functional transmembrane domain required for progelatinase A activation. J. biol. Chem., 270, 801-805 (1995).
6. COUSSENS, L.M. and WERB, Z., Matrix metalloproteinases and the development of cancer. Chem. Biol., 3, 895-904 (1996).
7. EMONARD, H.P., REMACLE, A.G., NOÈL, A., GRIMAUD, J.A., STETLER-STEVENSON, W.G. and FOIDART, J.M., Tumor cell surface-associated binding site for the 72,000 type IV collagenase. Cancer Res., 52, 5845-5848 (1992).
8. GOMEZ, D.E., ALONSO, D.F., YOSHIJI, H. and THORGEIRSSON, U.P., Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Europ. J. Cell Biol., 74, 111-122 (1997).
9. HEPPNER, K.J., MATRISIAN, L.M., JENSEN, R.A. and RODGERS, W.H., Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response. Amer. J. Pathol., 149, 273-282 (1996).
10. MASSON, R., LEFEBVRE, O., NOÈL, A., EL FAHIME, M., CHENARD, M.P., WENDLING, C., KEBERS, F., LEMEUR, M., DIERICH, A., FOIDART, J.M., BASSET, P. and RIO, M.C., In vivo evidence that the stromelysin-3 metalloproteinase contributes in a paracrine manner to epithelial cell malignancy. J. Cell Biol., 140, 1535-1541 (1998).
11. OHUCHI, E., IMAI, K., FUJII, Y., SATO, H., SEIKI, M. and OKADA, Y., Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules. J. biol. Chem., 272, 2446-2451 (1997).
12. OKADA, A., BELLOCQ, J.P., ROUYER, N., CHENARD, M.P., RIO, M.C., CHAMBON, P. and BASSET, P., Membrane-type matrix metalloproteinase (MT1-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas. Proc. nat. Acad. Sci. (Wash.), 92, 2730-2734 (1995).
13. PEI, D. and WEISS, S.J., Transmembrane-deletion mutants of the membrane-type matrix metalloproteinase 1 process progelatinase A and express intrinsic matrix-degrading activity. J. biol Chem., 271, 9135-9140 (1996).
14. POLETTE, M., NAWROCKI, B., GILLES, C., SATO, H., SEIKI, M., TOURNIER, J.M. and BIREMBAUT, P., MT-MMP expression and localisation in human lung and breast cancers. Virchows Arch., 428, 29-35 (1996).
15. PUENTE, X.S., PENDAS, A.M., LIANO, E., VELASCO, G. and LOPEZ-OTIN, C., Molecular cloning of a novel membrane-type matrix metalloproteinase from a human breast carcinoma. Cancer Res., 56, 944-949 (1996).
16. SANTAVICCA, M., NOÈL, A., CHENARD, M.P., LUTZ, Y., STOLL, I., SEGAIN, J.P., ROUYER, N., RIO, M.C., BELLOCQ, J.P. and BASSET, P., Characterization of monoclonal antibodies against stromelysin-3 and their use to evaluate sytromelysin-3 levels in breast carcinoma by semi-quantitative immunohistochemistry. Int. J. Cancer, 64, 336-341 (1995).
17. SATO, H. and SEIKI, M., Membrane-type matrix metalloproteinases (MT-MMPs) in tumor metastasis. J. Biochem., 119, 209-215 (1996).
18. SHOFUDA, K., YASUMITSU, H., NISHIHASHI, A., MIKI, K. and MIYAZAKI, K., Expression of three membrane-type matrix metalloproteinases (MT-MMPs) in rat vascular smooth muscle cells and characterization of MT3-MMPs with and without transmembrane domain. J. biol. Chem., 272, 9749-9754 (1997).
19. STETLER-STEVENSON, W.G., HEWITT, R. and CORCORAN, M., Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic. Semin. Cancer Biol., 7, 147-154 (1996).
20. STRONGIN, A., COLLIER, I., BANNIKOV, G., MARMER, B., GRANT, G. and GOLDBERG, G., Mechanism of cell surface activation of 72 kDa type IV collagenase. J. biol. Chem., 270, 5331-5338 (1995).
21. TAKINO, T., SATO, H., SHINAGAWA, A. and SEIKI, M., Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library: MT-MMPs form a unique membrane-type subclass in the MMP family. J. biol. Chem., 270, 23013-23020 (1995).
22. TRYGGVASON, K., HOYHTYA, M. and PIKE, C., Type IV collagenases in invasive tumors. Breast Cancer Res. Treat., 24, 209-218 (1993).
23. UENO, H., NAKAMURA, H., INOUE, M., IMAI, K., NOGUCHI, M., SATO, H., SEIKI, M. and OKADA, Y., Expression and tissue localization of membrane-type 1, 2, and 3 matrix metalloproteinases in human invasive breast carcinomas. Cancer Res., 57, 2055-2060 (1997).
24. WILL, H., ATKINSON, S., BUTLER, G., SMITH, B. and MURPHY, G., The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autocatalytic activation. J. biol. Chem., 271, 17119-17123 (1996).
25. WILL, H. and HINZMAN, B., cDNA sequence and mRNA tissue distribution of a novel human matrix metalloproteinase with a potential transmembrane segment. Europ. J. Biochem., 231, 602-608 (1995).
26. WILSON, C.L., HEPPNER, K.J., LABOSKY, P.A., HOGAN, B.L.M. and MATRISIAN, L., Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin. Proc. nat. Acad. Sci. (Wash.), 94, 1402-1407 (1997).
27. ZUCKER, S., DREWS, M., CONNER, C., FODA, H.D., DECLERCK, Y.A., LANGLEY, K.E., BAHOU, W.F., DOCHERTY, A.J.P. and CAO, J., Tissue inhibitor of metalloproteinase-2 (TIMP2) binds to the catalytic domain of the cell surface receptor membrane type 1-matrix metalloproteinase 1 (MT1-MMP). J. biol. Chem., 273, 1216-1222 (1998).