Retinoic acid receptor α and retinoid-X receptor-specific agonists synergistically target telomerase expression and induce tumor cell death

Oncogene

Volumn 22, Issue 57, 2003, Pages 9142-9150

  Pendino, Frédéric ^a   Dudognon, Charles ^a   Delhommeau, Francois ^b   Sahraoui, Tewfik ^a,c   Flexor, Maria ^a   Bennaceur Griscelli, Annelise ^b   Lanotte, Michel ^a   Ségal Bendirdjian, Evelyne ^a  

^a SAINT LOUIS HOSPITAL   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UNIVERSITY OF ORAN   (Algeria)

Author keywords

hTERT; Nuclear receptors; RAR; Retinoids; RXR; Telomerase

Indexed keywords

LIGAND; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; RETINOID X RECEPTOR; TELOMERASE;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CANCER THERAPY; CELL DEATH; CELL DIFFERENTIATION; CELL MATURATION; CONCENTRATION (PARAMETERS); DOWN REGULATION; DRUG TARGETING; ENZYME INACTIVATION; ENZYME REPRESSION; GENETIC TRANSCRIPTION; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; SIDE EFFECT; SIGNAL TRANSDUCTION; TELOMERE; TISSUE SPECIFICITY; TUMOR CELL;

CELL DEATH; CELL DIVISION; DNA-BINDING PROTEINS; DRUG SYNERGISM; GENETIC VECTORS; HUMANS; KINETICS; LEUKEMIA, PROMYELOCYTIC, ACUTE; PLASMIDS; RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; RETINOID X RECEPTORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TELOMERASE; TELOMERE; TRANSCRIPTION FACTORS; TRANSFECTION; TRETINOIN; TUMOR CELLS, CULTURED;

ATRA;

EID: 0346688563     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207093     Document Type: Article

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