Certification assays for HIV-1-based vectors: Frequent passage of gag sequences without evidence of replication-competent viruses

Molecular Therapy

Volumn 8, Issue 5, 2003, Pages 830-839

  Sastry, Lakshmi ^a   Xu, Yi ^a   Johnson, Terry ^a   Desai, Kunal ^a   Rissing, David ^a   Marsh, Jonathan ^a   Cornetta, Kenneth ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Lentivirus; p24 ELISA; PCR; Psi gag; RCL; Recombination; Safety; VSVG

Indexed keywords

ANTIGEN P24; GAG PROTEIN; GREEN FLUORESCENT PROTEIN; LENTIVIRUS VECTOR; VIRUS DNA; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN;

ARTICLE; CELL CULTURE; CELL LINE; CELL SCREENING; CONTROLLED STUDY; CULTURE MEDIUM; CYTOMEGALOVIRUS; DNA PACKAGING; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE AMPLIFICATION; GENE CONSTRUCT; GENE SEQUENCE; GENE TARGETING; GENE TRANSFER; GENETIC ANALYSIS; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; POLYMERASE CHAIN REACTION; PROMOTER REGION; SENSITIVITY ANALYSIS; VESICULAR STOMATITIS VIRUS; VIRAL GENE DELIVERY SYSTEM; VIRUS ENVELOPE; VIRUS RECOMBINATION; VIRUS REPLICATION;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; DNA VIRUSES; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; LENTIVIRUS; VESICULAR STOMATITIS VIRUS;

EID: 0346242699     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2003.08.003     Document Type: Article

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