Essential Role for Vascular Gelatinase Activity in Relaxin-Induced Renal Vasodilation, Hyperfiltration, and Reduced Myogenic Reactivity of Small Arteries

Circulation Research

Volumn 93, Issue 12, 2003, Pages 1249-1257

  Jeyabalan, Arundhathi ^a   Novak, Jacqueline ^a   Danielson, Lee A ^b   Kerchner, Laurie J ^a   Opett, Shannon L ^a   Conrad, Kirk P ^a,c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelin B receptor; Matrix metalloproteinases; Nitric oxide; Pregnancy; Renal circulation

Indexed keywords

ENDOTHELIN B RECEPTOR; GELATINASE; GELATINASE A; GELATINASE B; ILOMASTAT; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; NEUTRALIZING ANTIBODY; NITRIC OXIDE; PHOSPHORAMIDON; RECOMBINANT RELAXIN; RELAXIN; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; KIDNEY ARTERY; KIDNEY BLOOD FLOW; KIDNEY CIRCULATION; KIDNEY FUNCTION; KIDNEY VASCULAR RESISTANCE; MEAN ARTERIAL PRESSURE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RAT; VASODILATATION;

ANIMALS; ASPARTIC ENDOPEPTIDASES; DIPEPTIDES; FEMALE; GELATINASES; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PREGNANCY; PROTEASE INHIBITORS; RATS; RATS, LONG-EVANS; RECOMBINANT PROTEINS; RELAXIN; RENAL ARTERY; VASODILATION;

EID: 0346120209     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000104086.43830.6C     Document Type: Article

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